The U.S. dental bone graft substitute (DBGS) and biomaterials market was valued at $650 million in 2024 and is projected to grow at a CAGR of 6.8%, reaching over $1.0 billion by 2031.
Market growth is driven by:
Advancements in regenerative dental treatments.
Increasing demand for dental implants and periodontal procedures.
Growing adoption of dental biomaterials for tissue regeneration.
The 2025 report suite covers:
Dental Bone Graft Substitutes
Dental Growth Factors
Dental Barrier Membranes
Local Antimicrobial Periodontal Treatments
Dental Soft Tissue Regeneration
Collectively, these segments make up the dental biomaterials market.
Market Report Data Types Included
Unit Sales & Average Selling Prices (ASP)
Market Size & Growth Trends
Procedure Numbers
Market Drivers & Limiters
Market Forecasts Until 2031
Historical Data (2021-2023)
Competitive Analysis with Market Shares for Each Segment
Recent Mergers & Acquisitions
Company Profiles & Product Portfolios
Leading Competitors
U.S. Dental Bone Graft Substitute Market Trends
Limited Insurance Coverage Restricts Market Growth:
Most dental insurance plans do not cover implant and bone grafting procedures, leading to high out-of-pocket costs for patients.
Economic disparities limit access to advanced periodontal treatments.
Expanding insurance coverage could significantly increase procedural volume and drive market demand.
Market Growth Linked to Dental Implant Demand:
Bone graft substitutes are widely used in dental implant procedures.
As dental implant adoption rises, so does demand for regenerative materials.
U.S. Dental Bone Graft Substitute Market Share Insights (2024)
1 Geistlich – Market Leader
Dominant player in the DBGS and biomaterials market.
Strong presence in the dental bone graft substitute, dental barrier membrane, and soft tissue regeneration segments.
Key products include Bio-Oss®, Bio-Gide®, and Mucograft®.
Acquisition of Lynch Biologics in 2022 expanded its portfolio with GEM 21S®, reinforcing its leadership in dental growth factors.
2 ZimVie – Second-Largest Competitor
Broad portfolio across multiple dental biomaterial segments.
Key products include Puros® Allograft, Regeneross® line, and IngeniOs® synthetics.
Offers high-quality alternatives competing with top DBGS brands.
3 OraPharma – Third-Largest Competitor
Leader in the local antimicrobial periodontal treatment segment.
Flagship product ARESTIN® (minocycline HCl) Microspheres, 1 mg enhances periodontal treatment effectiveness.
Strong presence in periodontal disease management.
Market Segmentation Summary
Dental Bone Graft Substitute Market – Further segmented into:
Mineralized Allograft
Demineralized Bone Matrix (DMB) Allograft
Xenograft
Synthetics
Dental Growth Factor Market – Further segmented into:
Emdogain
GEM 21S®
Infuse
Osteocel®
Dental Barrier Membrane Market – Further segmented into:
Resorbable Membranes
Non-Resorbable Membranes
Local Antimicrobial Periodontal Treatment Market
Dental Soft Tissue Regeneration Market – Further segmented into:
Regeneration
Wound Care
Research Scope Summary
Regions Covered
United States
Base Year: 2024
Forecast Period: 2025-2031
Historical Data: 2021-2023
Quantitative Coverage
Market Size & Growth Rates
Procedure Numbers
Unit Sales & ASP
Market Shares & Forecasts through 2031
Qualitative Coverage
Market Growth Trends & Limiters
Competitive Analysis & SWOT for Top Competitors
Mergers & Acquisitions
Company Profiles & Product Portfolios
FDA Recalls & Regulatory Developments
Disruptive Technologies & Emerging Innovations
Disease Overviews
Data Sources
Primary Interviews with Industry Leaders
Government Physician Data
Regulatory Data
Hospital Private Data
Import & Export Data
iData Research Internal Database
- executive summary
- U.S. Dental Bone Graft Substitute and Other Biomaterials Market Overview
- Competitive Analysis
- Emerging Markets and Technologies
- Market Developments
- Market Trends
- Procedure Segmentation
- Market Segmentation
- Key Report Updates
- Version History
- research methodology
- Step 1: Project Initiation & Team Selection
- Step 2: Prepare Data Systems and Perform Secondary Research
- Step 3: Preparation for Interviews & Questionnaire Design
- Step 4: Performing Primary Research
- Step 5: Research Analysis: Establishing Baseline Estimates
- Step 6: Market Forecast and Analysis
- Step 7: Identify Strategic Opportunities
- Step 8: Final Review and Market Release
- Step 9: Customer Feedback and Market Monitoring
- U.S. Dental Bone Graft Substitute and Other Biomaterials Market Overview
- 2.1 Introduction
- 2.1.1 Applications of Dental Bone Graft Substitutes
- 2.1.1.1 Dental Implant Procedures
- 2.1.1.2 Periodontal Procedures
- 2.1.2 Types of Dental Bone Graft Substitutes
- 2.1.2.1 Autografts
- 2.1.2.2 Allografts
- 2.1.2.3 Demineralized Bone Matrix Allografts
- 2.1.2.4 Xenografts
- 2.1.2.5 Synthetics
- 2.1.3 Dental Growth Factor Products
- 2.1.4 Dental Membranes
- 2.1.5 Market Penetration and End Users
- 2.2 Market Overview & Trend Analysis
- 2.3 Drivers and Limiters
- 2.3.1 Market Drivers
- 2.3.2 Market Limiters
- 2.4 Competitive Market Share Analysis
- 2.5 Mergers and Acquisitions
- DENTAL BONE GRAFT SUBSTITUTE Market
- 3.1 Introduction
- 3.1.1 Autografts
- 3.1.2 Allografts
- 3.1.2.1 Mineralized Allografts
- 3.1.2.2 Demineralized Bone Matrix
- 3.1.3 Xenografts
- 3.1.4 Synthetics
- 3.2 Market Overview
- 3.2.1 Dental Bone Graft Substitute Market by Material
- 3.2.2 Dental Bone Graft Substitute Market by Care Setting
- 3.3 Market Analysis and Forecast
- 3.3.1 Dental Bone Graft Substitute Market
- 3.3.2 Dental Bone Graft Substitute Market by Material
- 3.3.2.1 Allograft Market by Material
- 3.3.2.1.1 Mineralized Allograft Market
- 3.3.2.1.2 Demineralized Bone Matrix Allograft Market
- 3.3.2.2 Xenograft Market
- 3.3.2.3 Synthetic Market
- 3.3.3 Dental Bone Graft Substitute Market by Care Setting
- 3.3.3.1 Dental Practice Market
- 3.3.3.2 Hospital Market
- 3.4 Unit Analysis
- 3.4.1 Dental Bone Graft and Substitute Units Placed by Material
- 3.4.2 Dental Bone Graft Substitute Units Sold by Procedure Type
- 3.5 Drivers and Limiters
- 3.5.1 Market Drivers
- 3.5.2 Market Limiters
- 3.6 Competitive Market Share Analysis
- Dental Growth Factor Market
- 4.1 Introduction
- 4.2 Market Overview
- 4.3 Market Analysis and Forecast
- 4.3.1 Emdogain® Market
- 4.3.2 GEM 21S® Market
- 4.3.3 Infuse® Market
- 4.3.4 Osteocel® Market
- 4.4 Drivers and Limiters
- 4.4.1 Market Drivers
- 4.4.2 Market Limiters
- 4.5 Competitive Market Share Analysis
- DENTAL Barrier Membrane Market
- 5.1 Introduction
- 5.2 Market Overview
- 5.2.1 Dental Barrier Membrane Market by Type
- 5.2.2 Dental Barrier Membrane Market by Material
- 5.3 Market Analysis and Forecast
- 5.3.1 Dental Barrier Membrane Market
- 5.3.2 Dental Barrier Membrane Market by Type
- 5.3.2.1 Resorbable Dental Barrier Membrane Market
- 5.3.2.2 Non-Resorbable Dental Barrier Membrane Market by Type
- 5.3.2.2.1 Non-Reinforced Non-Resorbable Dental Barrier Membrane Market
- 5.3.2.2.2 Titanium-Reinforced Non-Resorbable Dental Barrier Membrane Market
- 5.3.3 Dental Barrier Membrane Market by Material
- 5.3.3.1 Allograft Dental Barrier Membrane Market
- 5.3.3.2 Xenograft Dental Barrier Membrane Market
- 5.3.3.3 Synthetic Dental Barrier Membrane Market
- 5.4 Unit Analysis
- 5.4.1 Dental Barrier Membrane Units Sold by Size
- 5.4.1.1 Resorbable Dental Barrier Membrane Units Sold by Size
- 5.4.1.2 Non-Resorbable Dental Barrier Membrane Units Sold by Size
- 5.4.2 Dental Barrier Membrane Units Sold by Material
- 5.4.2.1 Xenograft Dental Barrier Membrane Units Sold by Type
- 5.4.2.2 Synthetic Dental Barrier Membrane Units Sold by Type
- 5.5 Drivers and Limiters
- 5.5.1 Market Drivers
- 5.5.2 Market Limiters
- 5.6 Competitive Market Share Analysis
- local Antimicrobial Periodontal Treatment Market
- 6.1 Introduction
- 6.2 Market Analysis and Forecast
- 6.3 Drivers and Limiters
- 6.3.1 Market Drivers
- 6.3.2 Market Limiters
- 6.4 Competitive Market Share Analysis
- Dental Soft Tissue Regeneration Market
- 7.1 Introduction
- 7.2 Market Overview
- 7.3 Market Analysis and Forecast
- 7.3.1 Total Dental Soft Tissue Regeneration Market
- 7.3.1.1 Allograft Dental Soft Tissue Regeneration Market
- 7.3.1.2 Xenograft Dental Soft Tissue Regeneration Market
- 7.3.2 Dental Soft Tissue Wound Care Market
- 7.3.2.1 Plug Dental Soft Tissue Wound Care Market
- 7.3.2.2 Tape Dental Soft Tissue Wound Care Market
- 7.3.2.3 Foam Dental Soft Tissue Wound Care Market
- 7.4 Drivers and Limiters
- 7.4.1 Market Drivers
- 7.4.2 Market Limiters
- 7.5 Competitive Market Share Analysis
- Abbreviations
- Chart 1-1: Dental Bone Graft Substitute and Other Biomaterials Market by Segment, U.S., 2024 – 2031
- Chart 1-2: Dental Bone Graft Substitute and Other Biomaterials Market Overview, U.S.,2024 & 2031
- Chart 2-1: Dental Bone Graft Substitute and Other Biomaterials Market by Segment, U.S., 2021 – 2031
- Chart 2-2: Leading Competitors, Dental Bone Graft Substitute and Other Biomaterials Market, U.S., 2024
- Chart 3-1: Dental Bone Graft Substitute Market by Material, U.S., 2021 – 2031
- Chart 3-2: Dental Bone Graft Substitute Market by Care Setting, U.S., 2021 – 2031
- Chart 3-3: Leading Competitors, Dental Bone Graft Substitute Market, U.S., 2024
- Chart 4-1: Dental Growth Factors Market by Segment, U.S., 2021 – 2031
- Chart 4-2: Leading Competitors, Dental Growth Factor Market, U.S., 2024
- Chart 5-1: Dental Barrier Membranes Market by Type, U.S., 2021 – 2031
- Chart 5-2: Dental Barrier Membranes Market by Material, U.S., 2021 – 2031
- Chart 5-3: Leading Competitors, Dental Barrier Membrane Market, U.S., 2024
- Chart 6-1: Local Antimicrobial Periodontal Treatment Market, U.S., 2021 – 2031
- Chart 6-2: Leading Competitors, Local Antimicrobial Periodontal Treatment Market, U.S., 2024
- Chart 7-1: Dental Soft Tissue Regeneration Market by Segment, U.S., 2021 – 2031
- Chart 7-2: Leading Competitors, Dental Soft Tissue Regeneration Market, U.S., 2024
- Figure 1-1: Dental Bone Graft Substitute and Other Biomaterials Market Share Ranking by Segment, U.S., 2024
- Figure 1-2: Companies Researched in This Report
- Figure 1-3: Recent Events in the Dental Bone Graft Substitute and Other Biomaterials Market, U.S., 2021 – 2025 (1 of 2)
- Figure 1-4: Recent Events in the Dental Bone Graft Substitute and Other Biomaterials Market, U.S., 2021 – 2025 (2 of 2)
- Figure 1-5: Factors Impacting the Dental Bone Graft Substitute and Other Biomaterials Market by Segment, U.S.
- Figure 1-6: Dental Bone Graft Substitute and Other Biomaterials Procedure Segmentation
- Figure 1-7: Dental Bone Graft Substitute and Other Biomaterials Market Segmentation (1 of 2)
- Figure 1-8: Dental Bone Graft Substitute and Other Biomaterials Market Segmentation (2 of 2)
- Figure 1-9: Key Report Updates
- Figure 1-10: Version History
- Figure 2-1: Dental Bone Graft Substitute and Other Biomaterials Market by Segment, U.S., 2021 – 2031 (US$M)
- Figure 2-2: Leading Competitors, Dental Bone Graft Substitute and Other Biomaterials Market, U.S., 2024
- Figure 3-1: Dental Bone Graft Substitute Market by Material, U.S., 2021 – 2031 (US$M)
- Figure 3-2: Dental Bone Graft Substitute Market by Care Setting, U.S., 2021 – 2031 (US$M)
- Figure 3-3: Total Dental Bone Graft Substitute Market by Type, U.S., 2021 – 2031
- Figure 3-4: Allograft Market by Material, U.S., 2021 – 2031 (US$M)
- Figure 3-5: Total Allograft Market, U.S., 2021 – 2031
- Figure 3-6: Mineralized Allograft Market, U.S., 2021 – 2031
- Figure 3-7: Demineralized Bone Matrix Allograft Market, U.S., 2021 – 2031
- Figure 3-8: Xenograft Market, U.S., 2021 – 2031
- Figure 3-9: Synthetic Market, U.S., 2021 – 2031
- Figure 3-10: Dental Practice Market, U.S., 2021 – 2031
- Figure 3-11: Hospital Market, U.S., 2021 – 2031
- Figure 3-12: Dental Bone Graft and Substitute Units Placed by Material, U.S., 2021 – 2031
- Figure 3-13: Bone Graft Substitute Units Sold by Procedure Type, U.S., 2021 – 2031
- Figure 3-14: Leading Competitors, Dental Bone Graft Substitute Market, U.S., 2024
- Figure 4-1: Dental Growth Factor Market by Segment, U.S., 2021 – 2031 (US$M)
- Figure 4-2: Emdogain® Market, U.S., 2021 – 2031
- Figure 4-3: GEM 21S® Market, U.S., 2021 – 2031
- Figure 4-4: Infuse® Market, U.S., 2021 – 2031
- Figure 4-5: Osteocel® Market, U.S., 2021 – 2031
- Figure 4-6: Leading Competitors, Dental Growth Factor Market, U.S., 2022
- Figure 5-1: Dental Barrier Membrane Market by Type, U.S., 2021 – 2031 (US$M)
- Figure 5-2: Dental Barrier Membrane Market by Material, U.S., 2021 – 2031 (US$M)
- Figure 5-3: Total Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-4: Resorbable Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-5: Dental Barrier Membrane Market by Material by Segment, U.S., 2021 – 2031 (US$M)
- Figure 5-6: Non-Resorbable Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-7: Non-Reinforced Non-Resorbable Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-8: Titanium-Reinforced Non-Resorbable Dental Barrier Membrane Market, U.S.,2021 – 2031
- Figure 5-9: Allograft Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-10: Xenograft Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-11: Synthetic Dental Barrier Membrane Market, U.S., 2021 – 2031
- Figure 5-12: Resorbable Dental Barrier Membrane Units Sold by Size, U.S., 2021 – 2031
- Figure 5-13: Non-Resorbable Dental Barrier Membrane Units Sold by Size, U.S., 2021 – 2031
- Figure 5-14: Dental Barrier Membrane Units Sold by Type, U.S., 2021 – 2031
- Figure 5-15: Xenograft Dental Barrier Membrane Units Sold by Type, U.S., 2021 – 2031
- Figure 5-16: Synthetic Dental Barrier Membrane Units Sold by Type, U.S., 2021 – 2031
- Figure 5-17: Leading Competitors, Dental Barrier Membrane Market, U.S., 2024
- Figure 6-1: Local Antimicrobial Periodontal Treatment Market, U.S., 2021 – 2031
- Figure 6-2: Leading Competitors, Local Antimicrobial Periodontal Treatment Market, U.S., 2024
- Figure 7-1: Dental Soft Tissue Regeneration Market by Segment, U.S., 2021 – 2031 (US$M)
- Figure 7-2: Dental Soft Tissue Regeneration Market by Segment, U.S., 2021 – 2031 (US$M)
- Figure 7-3: Total Dental Soft Tissue Regeneration Market, U.S., 2021 – 2031
- Figure 7-4: Allograft Dental Soft Tissue Regeneration Market, U.S., 2021 – 2031
- Figure 7-5: Xenograft Dental Soft Tissue Regeneration Market, U.S., 2021 – 2031
- Figure 7-6: Dental Soft Tissue Wound Care Market by Segment, U.S., 2021 – 2031 (US$M)
- Figure 7-7: Total Dental Soft Tissue Wound Care Market, U.S., 2021 – 2031
- Figure 7-8: Plug Dental Soft Tissue Wound Care Market, U.S., 2021 – 2031
- Figure 7-9: Tape Dental Soft Tissue Wound Care Market, U.S., 2021 – 2031
- Figure 7-10: Foam Dental Soft Tissue Wound Care Market, U.S., 2021 – 2031
- Figure 7-11: Leading Competitors, Dental Soft Tissue Regeneration Market, U.S., 2024
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