Lyophilization Equipment and Services

Lyophilization Equipment and Services

The lyophilization process provides preservation properties and is widely used in multiple industries throughout the world including, the food industry and pharmaceutical industry. It is a process in which an entirely frozen sample is placed under a vacuum with the purpose of removing water molecules or other solvents from the sample, allowing the ice to sublimate and transform directly from a solid to a vapor without passing through a liquid phase. The lyophilization equipment and services market has seen a potential rise in gaining the inclination of the pharmaceutical and food industries in the market. Apart from this many factors are responsible for propelling this market, like the surge in healthcare expenditure, growing demand and approvals for lyophilized drugs, and continuous investment by leading companies in research and development activities. The rising prevalence of biopharmaceuticals being manufactured globally represents one of the key factors driving the market. For instance, in June 2021, the U.S.-based SP Scientific Products launched its SP Hull LyoStar 4.0 R&D pilot-scale lyophilizer equipped with Process Analytical Technology tools and provides improved shelf mapping, reliability, process accuracy, and superior shelf freezing. Such factors have helped lyophilization equipment and services substantially gain prevalence in the market.

The Lyophilization Equipment and Services Market is expected to grow at a strong CAGR of 8.1% during the forecast period due to the rising pharmaceutical investment in the development of lyophilization equipment and services owing to which pharmaceutical companies are deeply engrossed in developing efficient lyophilization tools to maintain a competitive edge in the global market. For instance, in April 2022, NJM launched Dara Pharma Group's Coolvacuum freeze-drying equipment in the U.S. and Canada at the Interphex booth. The Coolvacuum product line includes a variety of lyophilization solutions, from small, standalone freeze dryers for research and development labs to large, fully integrated systems for commercial fill-finish packaging lines. Several other factors, initiatives for research and development activities, promising product pipeline and technological advancements, and increased demand for lyophilized products are driving the growth of the market during the forecast period. For instance, according to an article published in the Pharmaceutics Journal in July 2021, lyophilization is the most employed process for producing pharmaceutical products that are unstable and thermosensitive in an aqueous medium in order to ensure stability and long-term storage in the dried state.

• Based on procedures, the market is bifurcated into dryers and accessories. The accessories segment held the dominant share of the market in the year 2022 owing to the increased usage of accessories equipment to manufacture active pharmaceutical ingredients(AIP). Accessories include vacuum systems, clean-in-place systems, drying chambers, and other accessories including loading and unloading systems, control and monitoring systems, freeze drying, trays/shelves, manifolds, and others. They are easy to use and pocket-friendly for the consumers. An increasing demand for precision medicine and diagnostic tests is supposed to drive the dominance of accessories in the lyophilization equipment and services market. For instance, Telstar expanded the process laboratory service for freeze-drying and sterilization by incorporating cold sterilization methods for non-compatible medical and pharmaceutical products with conventional high-temperature sterilization in November 2022. Thus, the accessories segment held the dominant share of the market in the year 2022.
• By scope of operation, the market is segmented into industrial-scale, pilot-scale, and laboratory-scale. The laboratory-scale segment is anticipated to grow with significant CAGR during the forecast period majorly due to the rising prevalence of pharmaceutical products, and increasing clinical research. For instance, in February 2022, Interprotein Corporation and SPERA PHARMA Inc. entered into a strategic collaboration that aims at the various major health diseases through research & development and commercial manufacturing of peptide and novel molecules pharmaceutical products. Increased discovery of effective treatment options for trending diseases is also driving the growth of this segment. Thus, amongst the scope of operation, the laboratory-scale segment is expected to grow with a high CAGR during the forecast period.
• On the basis of application, the market is segmented into x, pharmaceutical and biotech manufacturing, medical applications, and others. The food processing and packaging segment held a significant share of the market in 2022 attributed to the advancements in food processing and storage infrastructure in food industries and increased usage and demand of packed food. For instance, in July 2022, Germany-based Leybold launched the NDi vacuum system for food packaging applications. This dry-running Novadry screw pump is reliable across the whole pressure range, and the integrated VA Control CAB controller for smart control forms the basis of the system. Thus, the food processing and packaging segment held a significant share of the market in 2022.
• For a better understanding of the market adoption of gynecological cancers therapeutics, the market is analyzed based on its worldwide presence in countries such as North America (U.S., Canada, and Rest of North America), Europe (Germany, U.K., France, Spain, Italy, Rest of Europe), Asia-Pacific (China, Japan, India, Rest of Asia-Pacific), Rest of World. APAC is expected to grow with the highest CAGR during the forecast period. Several factors, such as rising research and development activities, and a rising demand for pharmaceutical products in Southeast Asian countries are driving the regional market growth. For instance, in April 2023, PharmaJet Partner Gennova Biopharmaceuticals sought emergency use authorization in India for the use of GEMCOVAC-OM, the First Needle-Free mRNA Vaccine Omicron Booster. Countries such as India and China offer attractive investment opportunities for the lyophilization equipment and services market and are anticipated to positively drive demand prospects for the market. There are bulky investments and collaborations in the APAC region’s orthopedic treatment market. These factors would further boost the production of lyophilization equipment and services in the APAC region. Thus, APAC is anticipated to grow with a high CAGR during the forecast period.
• Some of the major players operating in the market include ATS Corporation; Azbil Corporation; Baxter; Coriolis Pharma; GEA Group Aktiengesellschaft; Labconco; Lyophilization Technology, Inc.; Martin Christ Gefriertrocknungsanlagen GmbH; MechaTech Systems Ltd.; Millrock Technology, Inc.