Chromatography Columns

Chromatography Columns

The chromatography columns market is expected to register a CAGR of approx. 6% over the period of 2023-2030. The global industry that revolves around the manufacturing, distribution, and sale of chromatography columns is referred to as the chromatography columns market. Chromatography columns are critical components in chromatography, a laboratory technique used to separate, identify, and analyze chemical compounds in a sample. Chromatography columns are typically cylindrical tubes filled with a stationary phase material that interacts with the components of a mixture as it goes through the column. The various chemicals in the sample separate due to their distinct affinities and interactions with the stationary phase, allowing for their isolation and analysis. The growing demand for chromatography columns can be attributed to the growing need for advanced analytical instruments in various industries, including pharmaceuticals, biotechnology, and environmental analysis are the key factors that boost the adoption of inorganic growth strategies among key industry players around the globe. For instance, In November 2021, Thermo Fisher Scientific, the industry leader in providing services to the scientific community, announced the acquisition of PharmaFluidics, a company established in Belgium and the developer of the PAC line of micro-chip-based chromatography columns. Owing to the glaring statistics increasing demand for analytical instruments across the globe would contribute to the growth of the market in the forthcoming period as well. Furthermore, the chromatography columns market is anticipated to grow on account of Continuous advancements in column materials, design, and packing techniques. Moreover, the rising demand for pharmaceuticals, along with the need for precise analysis and purification of drugs and biomolecules has led to a growing demand for chromatography columns in techniques. However, some of the restraints in the market including the high cost of chromatography columns and lack of expertise and training are impeding the growth of this market all over the world.

• Based on type, the market is segmented into high-performance liquid chromatography column, gas chromatographic column, and SPE solid phase extraction column. Among them, the high-performance liquid chromatography column segment captured a significant share of the market in 2021. HPLC is one of the most widely adopted chromatography techniques in various industries, including pharmaceuticals, biotechnology, environmental analysis, and food and beverage. Its versatility and broad applicability make HPLC columns in high demand.
• Based on column type, the market is segmented into normal phase chromatography columns, pre-packed chromatography columns, and automated chromatography columns. Among them, the automated chromatography columns segment captured a significant share of the market in 2021. Industries such as pharmaceuticals, biotechnology, and environmental analysis require high-throughput analysis capabilities to handle large sample volumes efficiently. Automated chromatography systems, including automated column switching and sample handling, enable faster and simultaneous analysis of multiple samples, improving productivity and efficiency.
• Based on the chromatography, the market is bifurcated into ion exchange chromatography, affinity chromatography, multimodal chromatography, gel filtration, and others. Among them, the ion exchange chromatography segment is expected to grow at a higher CAGR in the market. Ion exchange chromatography offers a unique separation mechanism based on the reversible exchange of ions between the sample components and the stationary phase. It enables the separation and purification of charged compounds, including proteins, peptides, nucleic acids, and small molecules, based on their ionic properties.
• Based on the capacity, the market is bifurcated into 1-100 Ml, 100-1000 Ml, and More Than 1L. Among them, the 100-1000 Ml segment is expected to grow at a higher CAGR in the market. Certain applications in industries such as pharmaceuticals, biotechnology, and food and beverage require larger sample volumes for analysis. The 100-1000 mL segment caters to these applications by providing columns with higher capacity and accommodating larger sample volumes.
• Based on the application, the market is bifurcated into sample preparation, resin screening, protein purification, anion and cation exchange, and desalting. Among them, the sample preparation segment is expected to grow at a higher CAGR in the market. Certain applications in industries such as pharmaceuticals, biotechnology, and food and beverage require larger sample volumes for analysis. The 100-1000 mL segment caters to these applications by providing columns with higher capacity and accommodating larger sample volumes.
• Based on the industry, the market is bifurcated into nutraceuticals, academics, food and beverages, pharmaceuticals, environmental biotechnology, cosmetics, and others. Among them, the pharmaceuticals segment is expected to grow at a higher CAGR in the market. The pharmaceutical industry is continually introducing new drugs to the market. Before these drugs can be approved and released, extensive analysis and testing are required to ensure their safety, efficacy, and quality. Chromatography columns play a crucial role in drug testing and quality assurance, driving their demand in the pharmaceutical segment.
• Based on the end-user, the chromatography columns market has been classified into analytical laboratories and research institutes. Among them, the analytical laboratories category grabbed a considerable market share, and it is expected to grow at a significant CAGR during the forecast period. the increased research and development operations conducted by such corporations for the discovery of innovative medicines and vaccines. Such investments are likely to increase the use of molecular biology techniques such as chromatography columns, which will benefit the market.
• For a better understanding of the market adoption of transfer membrane, the market is analyzed based on its worldwide presence in the countries such as North America (U.S., Canada, and the Rest of North America), Europe (Germany, France, Italy, Spain, U.K., and Rest of Europe), Asia-Pacific (China, Japan, India, and Rest of APAC), and Rest of World. North America, particularly the United States, is a hub for biotechnology and pharmaceutical research. The increasing demand for biopharmaceuticals in North America is a significant driver of the chromatography columns market. Biopharmaceuticals, such as monoclonal antibodies, vaccines, and cell therapies, require advanced chromatography techniques for purification and analysis, driving the demand for high-quality chromatography columns. For instance, in 2021, Agilent Technologies introduced the InfinityLab Bio Columns for Size Exclusion Chromatography (SEC) applications. These new columns are designed specifically for the analysis of biomolecules, including proteins and monoclonal antibodies. The InfinityLab Bio Columns offer high resolution and excellent reproducibility, catering to the growing demand for efficient biopharmaceutical analysis in the North America region and beyond. Moreover, North America is known for its significant contributions to scientific research and technological innovations. Advances in analytical technologies, including chromatography, drive the demand for high-quality chromatography columns in the region. Researchers and industries in North America often seek cutting-edge chromatography solutions to enhance their analytical capabilities, leading to increased adoption of advanced chromatography columns. For instance, in 2021, Waters Corporation announced the launch of the BioResolve RP mAb Polyphenyl 450 Å column. This innovative chromatography column is specifically designed for the analysis of monoclonal antibodies (mAbs) and other large biomolecules. The column's unique polyphenyl stationary phase offers excellent selectivity and resolution, enabling researchers in the North America region to achieve accurate and reliable results in biopharmaceutical analysis.
• Some of the major players operating in Merck KGaA, Luminex Corporation, Thermo Fisher Scientific, Agilent Technologies, Inc., Daicel Corporation, Shimadzu Corporation., PerkinElmer Inc., Bio-Rad Laboratories, Inc., Tosoh Corporation., Waters Corporation among others. Several M&A’s along with partnerships have been undertaken.