Bone Void Fillers

Bone Void Fillers

Bone void fillers are medical devices designed to provide an appropriate medium for patient recovery by addressing defects as a result of injury, illness, or surgery. These materials offer capacity, which is enhanced by offering support for the skeletal structures, healing of the bones as well as the provision of functional support for the affected area. The bioactive materials can be derived from ceramics, calcium phosphate, silicate bioglasses, polymers, and natural products such as collagen. The rising prevalence of orthopedic disorders, such as fractures, osteoporosis, and arthritis, contributes significantly to the demand for bone void fillers. As the global population ages, there is an increase in musculoskeletal injuries and diseases that require surgical intervention. According to the NHS, in 2022, around 69% of people aged 75 and over were estimated to be living with a musculoskeletal condition, compared with 23% of people aged 25–44. females, compared with males, were 5 times as likely to be living with osteoporosis and 1.4 times as likely to be living with arthritis.

The Bone Void Fillers Market is expected to grow with a significant CAGR of 6.8% during the forecast period (2024-2032). This can be attributed to the continued investment in research and development, which is crucial to developing innovative bone void fillers that enhance biocompatibility, durability, and effectiveness in promoting bone healing. This includes exploring new biomaterials, such as synthetic polymers and bioceramics, that mimic natural bone properties. In September 2021, Orthofix Medical Inc., a global medical device company with a spine and orthopedics focus, announced the full market launch of the Opus Mg Set osteoconductive scaffold, a synthetic magnesium-based bone void filler for orthopedic procedures.

• Based on the type, the market has been divided into demineralized bone, collagen matrix, matrix calcium sulfate, and tri-calcium phosphate. The demineralized bone held a dominant market share in 2023. This is mainly due to its unique biological properties and versatile orthopedic and spinal surgery applications. As demand for minimally invasive procedures and biocompatible materials grows, demineralized bone remains a cornerstone in the expanding bone void fillers market. For instance, in October 2022, Orthofix Medical Inc. announced the full market release and first implants of Legacy Demineralized Bone Matrix (DBM), a putty for filling voids or gaps in bony defects or traumatic injuries of the spine, pelvis, or extremities. Moreover, surgeons prefer demineralized bone due to its osteoconductive and osteoinductive properties, which provide structural support and stimulate new bone growth.
• Based on the form, the market is segmented into gel granules, paste putty, and others. The gel granules are expected to grow with a significant CAGR in the forecast period (2024-2032). These granules include ongoing hyaluronic acid or synthetic polymers that naturally resemble the bone extracellular matrix. They support cell attachment and growth while at the same time are hydrogel in nature to assume complex bone defects. New opportunities for gel granules are anticipated to emerge as biomaterials advance; applicants value their ability to adapt to patient’s requirements in regard to bone restoration during orthopedic and reconstructive operations.
• Based on the end-user, the market is segmented into hospitals, specialty clinics, and others. Hospitals held a dominant share of the market in 2023. Osteoporosis, fracture syndromes, and other orthopedic diseases also become more frequent, requiring effective remedies for their treatment, for example, the filling of bone defects. For instance, from 2019 to 2021 in the United States (NHIS), around 5.4% of adults 18 to 44 years old reported arthritis, and Among adults aged 45 to 64 years, one-in-four (26.0%) reported doctor-diagnosed arthritis. Moreover, hospitals are essential players in the clinical research of new technologies and materials for fillers, assessments of their effectiveness, and identification of possible negative consequences. The use of sophisticated instruments in surgeries and their focus on patients’ outcomes are other factors that will help expand the market.
• For a better understanding of the market adoption of bone void fillers, the market is analyzed based on its worldwide presence in countries such as North America (U.S., Canada, and the Rest of North America), Europe (Germany, France, U.K., Spain, Italy, Rest of Europe), Asia-Pacific (China, Japan, India, Rest of Asia-Pacific), Rest of World. Asia-Pacific is expected to grow with a significant CAGR in the forecast period (2024-2032). The region is experiencing rapid economic growth, and the healthcare sector expenditures continue to rise with improved admission to sophisticated medical procedures for patients with diseases such as arthritis and other orthopedic problems. An older population base in Asia-Pacific countries results in an emerging concern of orthopedics, which comprises osteoporosis, bone fractures, and degenerative arthritis. Furthermore, techniques like 3D printed implants and biodegradable neuroanatomy fillings are emerging trends for the services as they provide the exact fit of the human anatomy and give less chance of post-surgery infection.
• Some of the major players operating in the market include Stryker, Medical Device Business Services, Inc. (Johnson & Johnson), Medtronic, Zimmer Biomet, Smith+Nephew, Globus Medical, Orthofix Medical Inc., Baxter Arthrex, Inc., SeaSpine.