Viscosupplementation Market Forecasts to 2030 – Global Analysis By Product Type (Hyaluronic Acid (HA) Injections, Non-Hyaluronic Acid Products and Other Product Types), Source, Distribution Channel, Application and By Geography

According to Stratistics MRC, the Global Viscosupplementation Market is accounted for $5.4 billion in 2024 and is expected to reach $10.5 billion by 2030 growing at a CAGR of 11.5% during the forecast period. Viscosupplementation is a medical treatment for osteoarthritis (OA), primarily in the knee that involves injecting a gel-like substance, typically hyaluronic acid (HA), into the affected joint to supplement the natural synovial fluid. HA helps reduce pain and improve mobility by restoring the fluid's lubricating properties. This treatment is often used when conservative measures like pain medications or physical therapy have not provided sufficient relief. The procedure is minimally invasive, requiring just a few injections spaced over several weeks.

According to an article published by the Centers for Disease Control and Prevention in April 2020, titled ""Osteoarthritis"", about 32.5 million people in the United States are suffering from osteoarthritis. In addition to this, 62% of women suffer from osteoarthritis.

Market Dynamics:

Driver:

Rising incidence of osteoarthritis

Osteoarthritis is becoming more prevalent, especially in weight-bearing joints like the knee. The increasing number of people suffering from this condition is creating a growing demand for effective treatment options. Viscosupplementation, offering a non-invasive alternative to surgery, has gained popularity as an option to alleviate symptoms and improve joint mobility. With osteoarthritis affecting millions, the need for reliable therapies, such as viscosupplementation, will continue to expand during the forecast period.

Restraint:

Lack of reimbursement policies

The high cost of the treatment and limited insurance coverage can hinder patient access to viscosupplementation injections. The absence of comprehensive reimbursement options may deter patients from opting for the procedure, especially in areas with stricter healthcare policies. This cost-related barrier can slow the widespread adoption of viscosupplementation as a treatment for osteoarthritis. Overcoming these reimbursement challenges will be crucial to ensuring broader market penetration.

Opportunity:

Increasing adoption of minimally invasive procedures

As patients and healthcare providers prioritize less invasive treatment options with quicker recovery times, viscosupplementation offers a compelling alternative to traditional surgical interventions. The procedure’s non-invasive nature, coupled with its potential to reduce pain and improve mobility, positions it as a favorable choice for managing osteoarthritis. With the growing trend toward outpatient, minimally invasive procedures, viscosupplementation is expected to gain further traction, expanding its market share.

Threat:

Potential for adverse reactions

Viscosupplementation procedure can lead to side effects such as joint pain, swelling, or infection. The risk of these reactions may discourage some patients from choosing viscosupplementation as a treatment option. Additionally, adverse reactions, if not properly managed, could negatively impact the reputation of the treatment, creating hesitancy among both patients and healthcare providers. Addressing safety concerns and improving patient education is essential for minimizing this threat.

Covid-19 Impact

The Covid-19 pandemic had a mixed impact on the viscosupplementation market. On one hand, lockdowns and healthcare resource reallocations slowed elective procedures, including viscosupplementation injections, due to restricted access to clinics. On the other hand, the pandemic highlighted the importance of non-surgical treatments for managing chronic conditions like osteoarthritis, leading to a rebound in demand as healthcare systems adapted. With a growing focus on reducing hospital visits and promoting outpatient care, viscosupplementation may see sustained growth as a preferred treatment in the post-pandemic era.

The hyaluronic acid (HA) injections segment is expected to be the largest during the forecast period

The hyaluronic acid (HA) injections segment is expected to account for the largest market share during the forecast period owing to its ability to restore synovial fluid, providing lubrication and reducing inflammation in osteoarthritis -affected joints. Its proven effectiveness and long-standing use in viscosupplementation have made it the preferred choice for both patients and healthcare providers. As the most established and widely used form of viscosupplementation, the HA injections segment is anticipated to dominate the market in the coming years.

The non-animal source segment is expected to have the highest CAGR during the forecast period

Over the forecast period, the non-animal source segment is predicted to witness the highest growth rate due to increasing concerns over the potential risks of animal-derived products, non-animal-based hyaluronic acid offers a more attractive option for patients. These products cater to individuals who may have allergies or ethical concerns related to animal-based treatments. The demand for non-animal sourced viscosupplementation products is rising as they are perceived to be safer and more sustainable, offering manufacturers a growing opportunity to expand their market reach and meet consumer preferences.

Region with largest share:

During the forecast period, the North America region is expected to hold the largest market share owing to high awareness of osteoarthritis treatments, and significant healthcare spending. With a strong preference for non-invasive treatments like viscosupplementation, North America’s large aging population will drive continued demand. Furthermore, the presence of leading manufacturers and research institutions in the United States and Canada will support innovation and the growth of the viscosupplementation market throughout the forecast period.

Region with highest CAGR:

Over the forecast period, the Asia Pacific region is anticipated to exhibit the highest CAGR driven by rapid urbanization, increasing healthcare access, and a growing elderly population are contributing to the rising prevalence of osteoarthritis in this region. Countries like China, India, and Japan are seeing greater adoption of viscosupplementation due to rising healthcare awareness and improved medical facilities.

Key players in the market

Some of the key players in Viscosupplementation market include Anika Therapeutics, Inc., Aptissen, Bioventus LLC, Chugai Pharmaceuticals Co., Ltd., DePuy Synthes, F.Hoffmann-La Roche Ltd., Ferring Pharmaceuticals B.V., Fidia Farmaceutici S.p.A, Johnson & Johnson Services, Inc., LG Life Sciences Ltd., Lifecore Biomedical, OrthogenRx Inc., Sanofi, Seikagaku Corp., Smith & Nephew PLC and Zimmer Biomet.

Key Developments:

In November 2024, Roche announced that it has entered into a definitive merger agreement to acquire Poseida Therapeutics, Inc. a public clinical-stage biopharmaceutical company pioneering donor-derived CAR-T cell therapies.

In December 2024, Smith+Nephew announced its CORIOGRAPH Pre-Op Planning and Modeling Services are now cleared for total hip arthroplasty (THA) by the United States Food and Drug Administration.

Product Types Covered:
• Hyaluronic Acid (HA) Injections
• Non-Hyaluronic Acid Products
• Other Product Types

Sources Covered:
• Animal Source
• Non-Animal Source

Distribution Channels Covered:
• Direct Sales
• Clinics
• Retail Pharmacies & Drugstores
• Online Pharmacies & E-commerce Platforms
• Other Distribution Channels

Applications Covered:
• Osteoarthritis
• Post-Traumatic Arthritis
• Rheumatoid Arthritis
• Knee Osteoarthritis
• Other Applications

Regions Covered:
• North America
US
Canada
Mexico
• Europe
Germany
UK
Italy
France
Spain
Rest of Europe
• Asia Pacific
Japan
China
India
Australia
New Zealand
South Korea
Rest of Asia Pacific
• South America
Argentina
Brazil
Chile
Rest of South America
• Middle East & Africa
Saudi Arabia
UAE
Qatar
South Africa
Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2022, 2023, 2024, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements


1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 Emerging Markets
3.9 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Viscosupplementation Market, By Product Type
5.1 Introduction
5.2 Hyaluronic Acid (HA) Injections
5.2.1 Single-Injection Products
5.2.2 Multiple-Injection Products
5.2.3 Five-Injection Products
5.3 Non-Hyaluronic Acid Products
5.3.1 Collagen-Based Injections
5.3.2 Platelet-Rich Plasma
5.3.3 Stem Cell-Based Injections
5.4 Other Product Types
6 Global Viscosupplementation Market, By Source
6.1 Introduction
6.2 Animal Source
6.3 Non-Animal Source
7 Global Viscosupplementation Market, By Distribution Channel
7.1 Introduction
7.2 Direct Sales
7.3 Clinics
7.4 Retail Pharmacies & Drugstores
7.5 Online Pharmacies & E-commerce Platforms
7.6 Other Distribution Channels
8 Global Viscosupplementation Market, By Application
8.1 Introduction
8.2 Osteoarthritis
8.3 Post-Traumatic Arthritis
8.4 Rheumatoid Arthritis
8.5 Knee Osteoarthritis
8.6 Other Applications
9 Global Viscosupplementation Market, By Geography
9.1 Introduction
9.2 North America
9.2.1 US
9.2.2 Canada
9.2.3 Mexico
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 Italy
9.3.4 France
9.3.5 Spain
9.3.6 Rest of Europe
9.4 Asia Pacific
9.4.1 Japan
9.4.2 China
9.4.3 India
9.4.4 Australia
9.4.5 New Zealand
9.4.6 South Korea
9.4.7 Rest of Asia Pacific
9.5 South America
9.5.1 Argentina
9.5.2 Brazil
9.5.3 Chile
9.5.4 Rest of South America
9.6 Middle East & Africa
9.6.1 Saudi Arabia
9.6.2 UAE
9.6.3 Qatar
9.6.4 South Africa
9.6.5 Rest of Middle East & Africa
10 Key Developments
10.1 Agreements, Partnerships, Collaborations and Joint Ventures
10.2 Acquisitions & Mergers
10.3 New Product Launch
10.4 Expansions
10.5 Other Key Strategies
11 Company Profiling
11.1 Anika Therapeutics, Inc.
11.2 Aptissen
11.3 Bioventus LLC
11.4 Chugai Pharmaceuticals Co., Ltd.
11.5 DePuy Synthes
11.6 F.Hoffmann-La Roche Ltd.
11.7 Ferring Pharmaceuticals B.V.
11.8 Fidia Farmaceutici S.p.A
11.9 Johnson & Johnson Services, Inc.
11.10 LG Life Sciences Ltd.
11.11 Lifecore Biomedical
11.12 OrthogenRx Inc.
11.13 Sanofi
11.14 Seikagaku Corp.
11.15 Smith & Nephew PLC
11.16 Zimmer Biomet
List of Tables
Table 1 Global Viscosupplementation Market Outlook, By Region (2022-2030) ($MN)
Table 2 Global Viscosupplementation Market Outlook, By Product Type (2022-2030) ($MN)
Table 3 Global Viscosupplementation Market Outlook, By Hyaluronic Acid (HA) Injections (2022-2030) ($MN)
Table 4 Global Viscosupplementation Market Outlook, By Single-Injection Products (2022-2030) ($MN)
Table 5 Global Viscosupplementation Market Outlook, By Multiple-Injection Products (2022-2030) ($MN)
Table 6 Global Viscosupplementation Market Outlook, By Five-Injection Products (2022-2030) ($MN)
Table 7 Global Viscosupplementation Market Outlook, By Non-Hyaluronic Acid Products (2022-2030) ($MN)
Table 8 Global Viscosupplementation Market Outlook, By Collagen-Based Injections (2022-2030) ($MN)
Table 9 Global Viscosupplementation Market Outlook, By Platelet-Rich Plasma (2022-2030) ($MN)
Table 10 Global Viscosupplementation Market Outlook, By Stem Cell-Based Injections (2022-2030) ($MN)
Table 11 Global Viscosupplementation Market Outlook, By Other Product Types (2022-2030) ($MN)
Table 12 Global Viscosupplementation Market Outlook, By Source (2022-2030) ($MN)
Table 13 Global Viscosupplementation Market Outlook, By Animal Source (2022-2030) ($MN)
Table 14 Global Viscosupplementation Market Outlook, By Non-Animal Source (2022-2030) ($MN)
Table 15 Global Viscosupplementation Market Outlook, By Distribution Channel (2022-2030) ($MN)
Table 16 Global Viscosupplementation Market Outlook, By Direct Sales (2022-2030) ($MN)
Table 17 Global Viscosupplementation Market Outlook, By Clinics (2022-2030) ($MN)
Table 18 Global Viscosupplementation Market Outlook, By Retail Pharmacies & Drugstores (2022-2030) ($MN)
Table 19 Global Viscosupplementation Market Outlook, By Online Pharmacies & E-commerce Platforms (2022-2030) ($MN)
Table 20 Global Viscosupplementation Market Outlook, By Other Distribution Channels (2022-2030) ($MN)
Table 21 Global Viscosupplementation Market Outlook, By Application (2022-2030) ($MN)
Table 22 Global Viscosupplementation Market Outlook, By Osteoarthritis (2022-2030) ($MN)
Table 23 Global Viscosupplementation Market Outlook, By Post-Traumatic Arthritis (2022-2030) ($MN)
Table 24 Global Viscosupplementation Market Outlook, By Rheumatoid Arthritis (2022-2030) ($MN)
Table 25 Global Viscosupplementation Market Outlook, By Knee Osteoarthritis (2022-2030) ($MN)
Table 26 Global Viscosupplementation Market Outlook, By Other Applications (2022-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

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