Protein Purification and Isolation Market Forecasts to 2028 – Global Analysis By Product (Instruments and Consumables), Technology (Ultrafiltration, Precipitation, Preparative Chromatography, Electrophoresis, Western Blotting, Dialysis & Diafiltration and

Protein Purification and Isolation Market Forecasts to 2028 – Global Analysis By Product (Instruments and Consumables), Technology (Ultrafiltration, Precipitation, Preparative Chromatography, Electrophoresis, Western Blotting, Dialysis & Diafiltration and Centrifugation), Application (Biomarker Discovery, Disease Diagnostics & Monitoring, Drug Screening and Other Applications), End User and By Geography

According to Stratistics MRC, the Global Protein Purification and Isolation Market is accounted for $8.24 billion in 2022 and is expected to reach $17.40 billion by 2028 growing at a CAGR of 13.26% during the forecast period. Protein purification is the process of removing proteins using physical differences from complex mixtures of cells, tissues, or organisms. Large amounts of functional protein with few impurities are sought after by the protein purification procedure. In order to obtain the desired protein, the process separates proteins from non-protein components in a mixture. They are primarily used to categorize the protein's structure, function, and interactions. Affinity chromatography, immunoprecipitation, proteomics, or enzyme assays are a few of the frequently employed techniques for protein purification and isolation.

According to the report published by the Research America in January 2022, the biopharmaceutical companies invested around USD 122,204 million in 2020, wheras in 2019 the investment was around USD 110,932 million in R&D. Therefore, such fact is anticipated to drive the growth of the market in the country.

Market Dynamics:

Driver:

Increasing demand for rapid purification kits

One of the main factors fueling market expansion is the growing importance of discovering novel ligands, such as protein-based therapeutic compounds. The global protein purification and isolation market is being driven by the increasing demand for rapid purification kits to quickly screen, prepare, purify, and concentrate protein samples. The market is also expected to grow as a result of a number of factors, including increased funding from both public and private research organizations for R&D and expanding research in structure-based drug design.

Restraint:

High costs and time consuming process

Techniques for protein purification and isolation frequently require specialized tools, reagents, and personnel, which raises the overall cost. For researchers and institutions with limited resources, this may limit their access to these techniques. Additionally, the process of purifying and isolating proteins can be time-consuming and involve numerous steps, including cell lysis, chromatography, and filtration. Protein purification may be less effective and less scalable as a result of the drawn-out processes.

Opportunity:

Rising investments by governments

Increased government investments in R&D and programs fostering their growth and expansion benefit the pharmaceutical and biotechnology industries. Additionally, they offer benefits in the form of grants, regulations, and tax breaks. Due to the significant investments made in studying and creating molecules specific to biomarkers, the pharmaceutical industry is a very lucrative market for goods involving protein purification and isolation.

Threat:

Lack of universal purification techniques and regulatory requirements

Regulatory requirements and quality standards may apply to the protein purification and isolation process, particularly when it is used in biotechnology or pharmaceutical applications. The process as a whole may become more complicated and expensive due to compliance with these requirements. Additionally, there isn't a purification technique that can successfully isolate and purify every kind of protein. The process becomes more complex and variable as a result of the potential need for different proteins to be purified using specific methods tailored to their individual characteristics.

Covid-19 Impact

The protein purification and isolation market was negatively impacted by the supply chain disruption caused by COVID-19 and the delay in the delivery of crucial goods needed for the production of the kits, reagents, and consumables used in protein purification and isolation. A pandemic presents the market with a number of significant challenges, such as trucking bottlenecks and port checkpoints that slow down deliveries of essential supplies, export bans imposed in many nations, a dearth of operational manufacturing facilities, and a shortage of healthcare workers to transport and produce goods. As a result, this situation initially prevented market growth. The use of protein purification and isolation techniques for analysis and research involving the ever-emerging acute respiratory syndrome coronavirus (SARS-CoV-2) has, however, led to an increase in demand in recent years.

The consumables segment is expected to be the largest during the forecast period

During the forecast period, the consumables segment is anticipated to hold the largest market share for protein purification and isolation. The significant market share of this sector is primarily attributable to the frequent use of consumables for protein purification and the attention paid to the development of biopharmaceuticals by a variety of end users, including academic and medical research institutions and pharmaceutical firms.

The ultrafiltration segment is expected to have the highest CAGR during the forecast period

Over the forecast period, the ultrafiltration segment is anticipated to grow at the highest rate. Ultrafiltration is a technique used to remove dissolved molecules and incredibly small particles from liquids. The size of the molecules serves as the main basis for separation, though the sample's chemical, molecular, or electrostatic properties may also have an impact on the filter's permeability. Proteins and buffer components are typically separated using ultrafiltration for buffer exchange, concentration, or desalination. Ultrafiltration's benefits and widespread use in protein purification and isolation are the primary factors driving the segment's growth over the forecast period.

Region with largest share:

The presence of numerous protein purification market players, a developed research and development infrastructure, and technological developments in the proteomics sector all contribute to North America's continued dominance of the global protein purification market over the forecast period. The demand for technologically advanced protein isolation technologies in the North American market is also being driven by improved application fields like protein-protein interaction studies, target identification, drug screening, protein therapeutics, biomarker discovery, disease monitoring, and diagnostic tests.

Region with highest CAGR:

Over the forecast period, Asia-Pacific is anticipated to experience lucrative growth. The demand for protein purification and isolation solutions in this region is expected to be driven by government initiatives for the development of healthcare infrastructure in developing nations like China and India. Moreover, these governments are funding the creation of cutting-edge purification and isolation techniques. Additionally, initiatives promoting domestic pharmaceutical production and the high volume of biosimilar production contribute to the market's expansion.

Key players in the market

Some of the key players profiled in the Protein Purification and Isolation Market include Abcam plc, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Danaher, G.E. Healthcare Life Sciences, Kamada Ltd., Lanleys International Inc., Leaf Expression Systems, Major Science, Merck KGaA, MNPHARM, Mtibio, Noble Life Sciences, Inc., Norgen Biotek Corporation, Promega Corporation, Qiagen N.V., Sigma-Aldrich Corporation, Takara Bio Inc and Thermo Fischer Scientific, Inc.

Key Developments:

In June 2022, Merck and Mulliken Center for Theoretical Chemistry Collaborated in Machine Learning Project. The three-year collaboration will focus on developing new tools for computational chemistry modeling and new molecular representations.

In April 2022, Thermo Fisher Scientific Enhanced Clinical Research Solutions in Collaboration with Matrix Clinical Trials. The PPD clinical research business of Thermo Fisher Scientific Inc., the world leader in serving science, and Matrix Clinical Trials, a Matrix Medical Network offering, collaborated to bring clinical trials to patients with an innovative decentralized clinical trial (DCT) solution.

Products Covered:
• Instruments
• Consumables

Technologies Covered:
• Ultrafiltration
• Precipitation
• Preparative Chromatography
• Electrophoresis
• Western Blotting
• Dialysis & Diafiltration
• Centrifugation

Applications Covered:
• Biomarker Discovery
• Disease Diagnostics & Monitoring
• Drug Screening
• Protein Therapeutics
• Protein-Protein Interaction Studies
• Target Identification

End Users Covered:
• Academic Medical Institutes
• Hospitals & Diagnostics Centers
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations (CROs)

Regions Covered:
• North America
o US
o Canada
o Mexico
• Europe
o Germany
o UK
o Italy
o France
o Spain
o Rest of Europe
• Asia Pacific
o Japan
o China
o India
o Australia
o New Zealand
o South Korea
o Rest of Asia Pacific
• South America
o Argentina
o Brazil
o Chile
o Rest of South America
• Middle East & Africa
o Saudi Arabia
o UAE
o Qatar
o South Africa
o Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements