Market Research

Primary Cell Culture Market Forecasts to 2030 – Global Analysis By Product (Primary Cells, Reagents and Supplements and Other Products), Cell Type (Human Cells and Animal Cells), Separation Method, Application, End User and By Geography

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from $4,150 200 Pages Stratistics Market Research Consulting July, 2024 SMR19043967
Best Price Guarantee
Price from $4,150
Length 200 Pages
Publisher Stratistics Market Research Consulting
Published Date July, 2024
SKU SMR19043967

Primary Cell Culture Market Forecasts to 2030 – Global Analysis By Product (Primary Cells, Reagents and Supplements and Other Products), Cell Type (Human Cells and Animal Cells), Separation Method, Application, End User and By Geography


According to Stratistics MRC, the Global Primary Cell Culture Market is accounted for $5.62 billion in 2024 and is expected to reach $13.19 billion by 2030 growing at a CAGR of 15.3% during the forecast period. Primary cell culture refers to the process of isolating cells directly from a tissue or organism and growing them in vitro under controlled conditions. This method provides a culture that closely mimics the in vivo state of the cells, retaining most of their physiological, biochemical, and genetic characteristics. However, primary cultures have a limited lifespan and usually undergo senescence after a finite number of divisions.

According to WHO projections, the number of cancer deaths worldwide will continue to climb and will reach over 17 million by 2030.

Market Dynamics:

Driver:

Growing pharmaceutical and biotech sectors

The growing pharmaceutical and biotech sectors are driving the primary cell culture market by fueling the demand for innovative and reliable cell-based models. These sectors require high-quality primary cells for drug discovery, development, and testing, as they provide more physiologically relevant data compared to immortalized cell lines. Advances in personalized medicine and regenerative therapies further amplify the need for specific primary cells. Additionally, the increasing focus on biologics and biosimilars necessitates the use of primary cells to evaluate drug efficacy and safety.

Restraint:

Limited availability

The limited availability restraint in the Primary Cell Culture Market refers to the challenges in sourcing and obtaining primary cells for research and production. Primary cells are derived directly from tissues and have a finite lifespan, making them scarce and expensive. Isolation processes can be technically demanding and may yield limited quantities of viable cells. Additionally, donor variability, ethical considerations, and stringent regulatory requirements further restrict their availability.

Opportunity:

Advancements in 3D cell culture

Advancements in 3D cell culture technology are significantly enhancing the primary cell culture market. These technologies provide more physiologically relevant models by better mimicking the in vivo environment compared to traditional 2D cultures. Innovations such as scaffold-based systems, spheroids, and organoids allow for more accurate cell-cell and cell-matrix interactions. This leads to improved disease modeling, drug screening, and tissue engineering applications. Moreover, 3D cultures support the growth of primary cells that retain their differentiated state and functionality, making them valuable for personalized medicine and regenerative therapies.

Threat:

Reproducibility and standardization issues

In the primary cell culture market, reproducibility and standardization are critical challenges. Primary cells, derived directly from tissues, exhibit inherent biological variability, leading to inconsistent experimental outcomes. Standardization issues arise due to the lack of uniform protocols and quality controls, making it difficult to ensure consistency across different labs and experiments. Such challenges can hinder the reliability of research findings, affect the development of cell-based assays, and complicate regulatory approvals.

Covid-19 Impact:

The COVID-19 pandemic significantly impacted the primary cell culture market, primarily through disruptions in supply chains and operational delays in laboratories. Increased demand for research related to SARS-CoV-2 spurred growth in the market, as primary cell cultures became crucial for studying virus behavior, developing vaccines, and testing antiviral drugs. Laboratories pivoted to COVID-19 research, which accelerated innovation and funding in cell culture technologies. However, the focus on pandemic-related studies also caused delays in non-COVID-19 research, affecting the overall research pipeline and project timelines.

The primary cells segment is expected to be the largest during the forecast period

The growth of the primary cells segment in the primary cell culture market can be attributed to several factors. There is increasing demand for more physiologically relevant cellular models for drug development and testing, which primary cells provide due to their direct extraction from tissues. This segment benefits from advancements in isolation techniques that preserve cellular integrity and function, enhancing their utility in research and clinical applications. Additionally, primary cells offer researchers the ability to study complex cellular interactions and disease mechanisms more accurately compared to immortalized cell lines.

The enzymatic degradation segment is expected to have the highest CAGR during the forecast period

Enzymatic degradation in the primary cell culture market is the process of using enzymes to dissociate cells from tissues or to degrade unwanted cellular components during cell culture. This segment's growth is driven by the increasing demand for efficient and gentle methods of cell isolation and maintenance. Enzymes such as trypsin, collagenase, and dispase are crucial in achieving high cell yields with minimal damage, thereby supporting various applications in research, drug development, and regenerative medicine. Advancements in enzyme technology, including the development of recombinant enzymes and improved formulations, further enhance the reliability and specificity of enzymatic degradation methods.

Region with largest share:

The North American region has experienced significant growth in the primary cell culture market due to several factors. First, there is increasing research and development activity in the biotechnology and pharmaceutical sectors, driving demand for primary cell culture techniques for drug discovery and development. The rising prevalence of chronic diseases and the need for personalized medicine have emphasized the importance of primary cell cultures in studying disease mechanisms and developing targeted therapies. Moreover, collaborations between academic institutions, research organizations, and industry players have contributed to the region's growth by facilitating knowledge exchange.

Region with highest CAGR:

The Asia-Pacific region has witnessed significant growth in the primary cell culture market due to several factors. Increasing investments in the biotechnology and pharmaceutical industries across countries like China, India, Japan, and South Korea have driven demand. These nations are expanding their research capabilities and infrastructure, fostering a conducive environment for cell culture technologies. Additionally, the rising prevalence of chronic diseases has fuelled the need for advanced research in drug development, further boosting the market.

Key players in the market

Some of the key players in Primary Cell Culture market include American Type Culture Collection, Axol Bioscience Ltd., BioIVT, CGT Global, Corning Incorporated, Creative Bioarray, Cyagen , Danaher, Epithelix Sàrl, FUJIFILM Wako Pure Chemical Corporation, HemaCare Corporation, Lonza Bioscience, Mattek, Merck KGaA, Neuromics, PPA Research Group, Inc., ReachBio LLC, STEMCELL Technologies, Thermo Fisher Scientific Inc. and XenoTech, LLC.

Key Developments:

In February 2024, BioIVT announced it has increased its capacity to deliver readily-available fresh, standard and mobilized, human leukopaks. Building on decades of human derived cell collection expertise, this additional capability enables BioIVT to further scale its world-class network of diverse, highly characterized donors and makes the company a leading provider of fresh leukopaks in the UK and mainland Europe.

In June 2024, Danaher Corporation has launched a strategic collaboration with Cincinnati Children's Hospital Medical Center, with the goal of improving patient safety by addressing a leading cause of failure in clinical trials. As part of the Danaher Beacons program, the multi-year collaboration aims to improve liver organoid technology as a drug toxicity screening solution for safeguarding patients.

Products Covered:
• Primary Cells
• Reagents and Supplements
• Media
• Other Products

Cell Types Covered:
• Human Cells
• Animal Cells

Separation Methods Covered:
• Enzymatic Degradation
• Explant Method
• Mechanical Separation
• Other Separation Methods

Applications Covered:
• Vaccine Production
• Virology
• Cell & Gene Therapy Development
• Model System
• Stem Cell Therapy
• Cancer Research
• Prenatal Diagnosis
• Other Applications

End Users Covered:
• Academic and Research Institutions
• Contract Research Organizations (CROs)
• Pharmaceutical and Biotechnology Companies
• Other End Users

Regions Covered:
• North America
US
Canada
Mexico
• Europe
Germany
UK
Italy
France
Spain
Rest of Europe
• Asia Pacific
Japan
China
India
Australia
New Zealand
South Korea
Rest of Asia Pacific
• South America
Argentina
Brazil
Chile
Rest of South America
• Middle East & Africa
Saudi Arabia
UAE
Qatar
South Africa
Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2022, 2023, 2024, 2026, and 2030
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements


1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Primary Cell Culture Market, By Product
5.1 Introduction
5.2 Primary Cells
5.2.1 Blood Cells
5.2.2 Bone Cells
5.2.3 Endothelial Cells
5.2.4 Fat Cells
5.2.5 Muscle Cells
5.2.6 Nerve Cells
5.2.7 Skin Cells
5.2.8 Other Cells
5.3 Reagents and Supplements
5.3.1 Sera
5.3.2 Growth Factors and Cytokines
5.3.3 Buffers and Salts
5.3.4 Attachment Solutions
5.3.5 Other Reagents and Supplements
5.4 Media
5.5 Other Products
6 Global Primary Cell Culture Market, By Cell Type
6.1 Introduction
6.2 Human Cells
6.3 Animal Cells
7 Global Primary Cell Culture Market, By Separation Method
7.1 Introduction
7.2 Enzymatic Degradation
7.2.1 Trypsin
7.2.2 Protease
7.2.3 Pronase
7.2.4 Papain
7.2.5 Neuraminidase
7.2.6 Hyaluronidase
7.2.7 Elastase
7.2.8 DNase
7.2.9 Dispane
7.2.10 Collagenase
7.2.11 Accutase
7.2.12 Other Enzymatic Degradations
7.3 Explant Method
7.4 Mechanical Separation
7.5 Other Separation Methods
8 Global Primary Cell Culture Market, By Application
8.1 Introduction
8.2 Vaccine Production
8.3 Virology
8.4 Cell & Gene Therapy Development
8.5 Model System
8.6 Stem Cell Therapy
8.7 Cancer Research
8.8 Prenatal Diagnosis
8.9 Other Applications
9 Global Primary Cell Culture Market, By End User
9.1 Introduction
9.2 Academic and Research Institutions
9.3 Contract Research Organizations (CROs)
9.4 Pharmaceutical and Biotechnology Companies
9.5 Other End Users
10 Global Primary Cell Culture Market, By Geography
10.1 Introduction
10.2 North America
10.2.1 US
10.2.2 Canada
10.2.3 Mexico
10.3 Europe
10.3.1 Germany
10.3.2 UK
10.3.3 Italy
10.3.4 France
10.3.5 Spain
10.3.6 Rest of Europe
10.4 Asia Pacific
10.4.1 Japan
10.4.2 China
10.4.3 India
10.4.4 Australia
10.4.5 New Zealand
10.4.6 South Korea
10.4.7 Rest of Asia Pacific
10.5 South America
10.5.1 Argentina
10.5.2 Brazil
10.5.3 Chile
10.5.4 Rest of South America
10.6 Middle East & Africa
10.6.1 Saudi Arabia
10.6.2 UAE
10.6.3 Qatar
10.6.4 South Africa
10.6.5 Rest of Middle East & Africa
11 Key Developments
11.1 Agreements, Partnerships, Collaborations and Joint Ventures
11.2 Acquisitions & Mergers
11.3 New Product Launch
11.4 Expansions
11.5 Other Key Strategies
12 Company Profiling
12.1 American Type Culture Collection
12.2 Axol Bioscience Ltd.
12.3 BioIVT
12.4 CGT Global
12.5 Corning Incorporated
12.6 Creative Bioarray
12.7 Cyagen
12.8 Danaher
12.9 Epithelix Sàrl
12.10 FUJIFILM Wako Pure Chemical Corporation
12.11 HemaCare Corporation
12.12 Lonza Bioscience
12.13 Mattek
12.14 Merck KGaA
12.15 Neuromics
12.16 PPA Research Group, Inc.
12.17 ReachBio LLC
12.18 STEMCELL Technologies
12.19 Thermo Fisher Scientific Inc.
12.20 XenoTech, LLC
List of Tables
Table 1 Global Primary Cell Culture Market Outlook, By Region (2022-2030) ($MN)
Table 2 Global Primary Cell Culture Market Outlook, By Product (2022-2030) ($MN)
Table 3 Global Primary Cell Culture Market Outlook, By Primary Cells (2022-2030) ($MN)
Table 4 Global Primary Cell Culture Market Outlook, By Blood Cells (2022-2030) ($MN)
Table 5 Global Primary Cell Culture Market Outlook, By Bone Cells (2022-2030) ($MN)
Table 6 Global Primary Cell Culture Market Outlook, By Endothelial Cells (2022-2030) ($MN)
Table 7 Global Primary Cell Culture Market Outlook, By Fat Cells (2022-2030) ($MN)
Table 8 Global Primary Cell Culture Market Outlook, By Muscle Cells (2022-2030) ($MN)
Table 9 Global Primary Cell Culture Market Outlook, By Nerve Cells (2022-2030) ($MN)
Table 10 Global Primary Cell Culture Market Outlook, By Skin Cells (2022-2030) ($MN)
Table 11 Global Primary Cell Culture Market Outlook, By Other Cells (2022-2030) ($MN)
Table 12 Global Primary Cell Culture Market Outlook, By Reagents and Supplements (2022-2030) ($MN)
Table 13 Global Primary Cell Culture Market Outlook, By Sera (2022-2030) ($MN)
Table 14 Global Primary Cell Culture Market Outlook, By Growth Factors and Cytokines (2022-2030) ($MN)
Table 15 Global Primary Cell Culture Market Outlook, By Buffers and Salts (2022-2030) ($MN)
Table 16 Global Primary Cell Culture Market Outlook, By Attachment Solutions (2022-2030) ($MN)
Table 17 Global Primary Cell Culture Market Outlook, By Other Reagents and Supplements (2022-2030) ($MN)
Table 18 Global Primary Cell Culture Market Outlook, By Media (2022-2030) ($MN)
Table 19 Global Primary Cell Culture Market Outlook, By Other Products (2022-2030) ($MN)
Table 20 Global Primary Cell Culture Market Outlook, By Cell Type (2022-2030) ($MN)
Table 21 Global Primary Cell Culture Market Outlook, By Human Cells (2022-2030) ($MN)
Table 22 Global Primary Cell Culture Market Outlook, By Animal Cells (2022-2030) ($MN)
Table 23 Global Primary Cell Culture Market Outlook, By Separation Method (2022-2030) ($MN)
Table 24 Global Primary Cell Culture Market Outlook, By Enzymatic Degradation (2022-2030) ($MN)
Table 25 Global Primary Cell Culture Market Outlook, By Trypsin (2022-2030) ($MN)
Table 26 Global Primary Cell Culture Market Outlook, By Protease (2022-2030) ($MN)
Table 27 Global Primary Cell Culture Market Outlook, By Pronase (2022-2030) ($MN)
Table 28 Global Primary Cell Culture Market Outlook, By Papain (2022-2030) ($MN)
Table 29 Global Primary Cell Culture Market Outlook, By Neuraminidase (2022-2030) ($MN)
Table 30 Global Primary Cell Culture Market Outlook, By Hyaluronidase (2022-2030) ($MN)
Table 31 Global Primary Cell Culture Market Outlook, By Elastase (2022-2030) ($MN)
Table 32 Global Primary Cell Culture Market Outlook, By DNase (2022-2030) ($MN)
Table 33 Global Primary Cell Culture Market Outlook, By Dispane (2022-2030) ($MN)
Table 34 Global Primary Cell Culture Market Outlook, By Collagenase (2022-2030) ($MN)
Table 35 Global Primary Cell Culture Market Outlook, By Accutase (2022-2030) ($MN)
Table 36 Global Primary Cell Culture Market Outlook, By Other Enzymatic Degradations (2022-2030) ($MN)
Table 37 Global Primary Cell Culture Market Outlook, By Explant Method (2022-2030) ($MN)
Table 38 Global Primary Cell Culture Market Outlook, By Mechanical Separation (2022-2030) ($MN)
Table 39 Global Primary Cell Culture Market Outlook, By Other Separation Methods (2022-2030) ($MN)
Table 40 Global Primary Cell Culture Market Outlook, By Application (2022-2030) ($MN)
Table 41 Global Primary Cell Culture Market Outlook, By Vaccine Production (2022-2030) ($MN)
Table 42 Global Primary Cell Culture Market Outlook, By Virology (2022-2030) ($MN)
Table 43 Global Primary Cell Culture Market Outlook, By Cell & Gene Therapy Development (2022-2030) ($MN)
Table 44 Global Primary Cell Culture Market Outlook, By Model System (2022-2030) ($MN)
Table 45 Global Primary Cell Culture Market Outlook, By Stem Cell Therapy (2022-2030) ($MN)
Table 46 Global Primary Cell Culture Market Outlook, By Cancer Research (2022-2030) ($MN)
Table 47 Global Primary Cell Culture Market Outlook, By Prenatal Diagnosis (2022-2030) ($MN)
Table 48 Global Primary Cell Culture Market Outlook, By Other Applications (2022-2030) ($MN)
Table 49 Global Primary Cell Culture Market Outlook, By End User (2022-2030) ($MN)
Table 50 Global Primary Cell Culture Market Outlook, By Academic and Research Institutions (2022-2030) ($MN)
Table 51 Global Primary Cell Culture Market Outlook, By Contract Research Organizations (CROs) (2022-2030) ($MN)
Table 52 Global Primary Cell Culture Market Outlook, By Pharmaceutical and Biotechnology Companies (2022-2030) ($MN)
Table 53 Global Primary Cell Culture Market Outlook, By Other End Users (2022-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

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