Huntington’s Disease Treatment Market Forecasts to 2028 – Global Analysis By Treatment (Disease-modifying therapies and Symptomatic treatment), Drug, End User and By Geography
According tStratistics MRC, the Global Huntington’s Disease Treatment Market is accounted for $8.5 billion in 2022 and is expected treach $18.7 billion by 2028 growing at a CAGR of 14.1% during the forecast period. Huntington’s disease is a rare inherited disease that causes progressive breakdown of nerve cells in the brain, mainly affecting physical movements, emotions and cognitive abilities. It is a condition in which the nerve cells of the brain malfunction and create clumps of a protein called neurofibrillary tangles that affect movement, thinking, reasoning, moods, and more. It can cause uncontrolled movements or muscle twitches (chorea), changes in speech patterns, depression, anxiety, and personality changes.
According tthe Huntington’s disease Society of America (HDSA), there were approximately 41,000 symptomatic Americans in 2021, with over 200,000 individuals at risk of inheriting the disease.
Market Dynamics:
Driver:
The rising incidence of Huntington's disease
The rising incidence of Huntington's disease across the globe is one of the primary factors driving the market growth. The procedure is frequently used tstop uncontrollable jerking and writhing motion, which enhances quality of life. In addition, clinical trials, strong drug type pipeline and growing adoption of improved medical treatments and therapies are expected tfuel the market growth.
Restraint:
Lack of approved drugs and stringent regulatory policies
Currently, there are only twdrugs approved for the treatment of chorea associated with this condition and these drugs can only manage or control the symptoms but cannot cure the disease. Companies across the globe need tclear strict regulatory hurdles for the approval of drugs. Such regulatory limits may impact market participants' preferences, resulting in slower market growth during the projection period.
Opportunity:
Growing research and development activities
There is a vast area of research and development for Huntington's disease treatment approaches because there is neffective treatment or medication. This is expected tsignificantly boost market growth during the forecast period. Moreover, the promising government initiatives that promote the development of new drugs are estimated tbe another factor supporting the market growth.
Threat:
Limited availability of drugs
The number of licensed pharmaceuticals is limited due ttight policies and restrictions. It is anticipated that the market's expansion will be constrained by the lack of knowledge about this illness in many regions of the world. Many medications have failed tshow efficacy or have been linked tsignificant toxicity, which has presented significant challenges for the discovery of drugs ttreat the disease. This is expected thamper the market growth.
Covid-19 Impact
The COVID-19 outbreak is projected thave a detrimental effect on the size of the market for treating Huntington's disease. Taccommodate more patients with COVID-19, a sizable number of clinics and hospitals around the world underwent restructuring. Because of the sharp increase in patients, non-essential operations could be delayed. Production and delivery of supplies for healthcare were halted as a result of the lockdown. Lack of access thealthcare, a staffing deficit in the medical field, and an increase in COVID-19-related hospitalisation are some additional variables that have an impact on the market.
The disease-modifying therapies segment is expected tbe the largest during the forecast period
The disease-modifying therapies segment is estimated thave a lucrative growth, due tan increase in disease-modifying therapy R&D. They can be administered intravenously or orally tlessen current symptoms or slow their progression. Disease-modifying therapies can help with problems like psychological illnesses and depression linked tthis condition, but they have not been found tchange patient mortality rates.
The antidepressants segment is expected thave the highest CAGR during the forecast period
The antidepressants segment is anticipated twitness the fastest CAGR growth during the forecast period, due tthey are intended trestore the mental stability. Antidepressants are prescription medications that can help with symptoms of clinical depression, dysthymia, social anxiety, anxiety, and other conditions. Treatment with antidepressants focuses primarily on reducing the symptoms of severe depression. These are driving the segment growth.
Region with Largest share:
Asia Pacific is projected thold the largest market share during the forecast period owing tthe comparatively lower prevalence rate of this condition amongst the population. However, increasing awareness among the patient population toward available treatment along with improving reimbursement policies in these regions during the forecast period will contribute ttheir growth prospects.
Region with highest CAGR:
North America is projected thave the highest CAGR over the forecast period, owing tthe increasing product penetration. A high level of public awareness about the condition, as well as growing support from numerous public and private organisations through research funding, texpedite the study of this disease. As governments take more initiatives timprove the health status of the populations, the market in the region is expected tgrow.
Key players in the market
Some of the key players profiled in the Huntington’s Disease Treatment Market include Novartis AG, Teva Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Sun Pharmaceutical Industries, Inc., Lupin, Hetero, Hikma Pharmaceuticals PLC, Bausch Health Companies Inc., Alterity Therapeutics, H. Lundbeck A/S, Neurocrine Biosciences, Inc., Annexon Biosciences, PTC Therapeutics, Prilenia Therapeutics, Amneal Pharmaceuticals LLC., SOM BIOTECH and Vertex Pharmaceuticals Incorporated.
Key Developments:
In December 2021, Novartis AG received Fast Track designation for Branaplam from the FDA for Huntington’s disease treatment. Branaplam is an mRNA splicing modulator that targets the HTT protein responsible for causing the degeneration of nerve cells leading tHuntington’s disease.
In October 2021, Teva Pharmaceutical Industries Ltd. received marketing approval for the treatment of chorea associated with Huntington’s disease treatment and for the treatment of tardive dyskinesia in Brazil.
Treatments Covered:
• Disease-modifying therapies
• Symptomatic treatment
Drugs Covered:
• Antidepressants
• Antipsychotic Drugs
• Tranquilizers
• Tetrabenazine
• Other Drugs
End Users Covered:
• Clinics
• Hospital
• Retail Pharmacies
• Online Pharmacies
• Other End Users
Regions Covered:
• North America
US
Canada
Mexico
• Europe
Germany
UK
Italy
France
Spain
Rest of Europe
• Asia Pacific
Japan
China
India
Australia
New Zealand
South Korea
Rest of Asia Pacific
• South America
Argentina
Brazil
Chile
Rest of South America
• Middle East & Africa
Saudi Arabia
UAE
Qatar
South Africa
Rest of Middle East & Africa
What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2020, 2021, 2022, 2025, and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements
Learn how to effectively navigate the market research process to help guide your organization on the journey to success.
Download eBook