mRNA Vaccine and Therapeutics Market by Application Area (Covid-19 and Other Indications), Target Disease Indication (Influenza, Respiratory Syncytial Virus Infection and Cytomegalovirus Diseases) and Geographical Regions (North America, Europe, Asia-Pacific, Latin America and Rest of the World): Industry Trends and Global Forecasts, Till 2035
mRNA Vaccine And Therapeutics Market: Overview
As per Roots Analysis, the global mRNA vaccine and therapeutics market is estimated to be worth USD 1.99 billion by 2035, primarily driven by the anticipated approval of mRNA vaccines and therapeutics intended for the treatment of infectious diseases.
The market sizing and opportunity analysis has been segmented across the following parameters:
Application Area
- COVID-19
- Other Indications
Target Disease Indication
- Influenza
- Respiratory Syncytial Virus Infection
- Cytomegalovirus Diseases
Key Geographical Regions
- North America
- Europe
- Asia-Pacific
- Latin America
- Rest of the World
MRNA VACCINE AND THERAPEUTICS MARKET: GROWTH AND TRENDS
Messenger ribonucleic acid (mRNA) is a form of single-stranded ribonucleic acid (RNA) that is crucial role in transferring genetic information for protein production. The mRNA carries the coding instructions for protein synthesis from a DNA strand to the ribosomes, where these instructions are translated and processed into functional proteins.
In recent years, mRNA technology has revolutionized the pharmaceutical industry to prevent and treat a wide array of diseases and disorders. The success of COVID-19 vaccines has paved the path for mRNA vaccines and therapeutics. It is worth highlighting that, in the past few years, more than 170 clinical trials related to mRNA-based therapeutics / vaccines have been registered. Multiple preclinical and clinical studies show the efficacy of these platforms which have been published in the last two years across different research articles. This demonstrates the extensive development efforts being undertaken by stakeholders in this domain. At present, over 45 industry players are engaged in the development of mRNA drug candidates for a wide range of disease indications.
The success of COVID-19 vaccines, growing research activity and the rich pipeline of mRNA drug candidates is likely to drive the global mRNA vaccine and therapeutics market in the coming decade.
MRNA VACCINE AND THERAPEUTICS MARKET: KEY INSIGHTS
The report delves into the current state of the mRNA vaccine and therapeutics market and identifies potential growth opportunities within the industry. Some key findings from the report include:
1. Presently, over 235 mRNA drug candidates are available in the market or under development; majority of these drug candidates are vaccines using lipid nanoparticles as delivery systems.
2. The pipeline features several drugs, which are being investigated across different phases of development; 60% of the drug candidates are designed to be administered via intramuscular routes.
3. The current market landscape of mRNA vaccine and therapeutics developers is fragmented, featuring the presence of both new entrants and established players; majority of these players are based in the US.
4. Stakeholders are actively upgrading their existing capabilities to further enhance their respective product pipeline and comply with the evolving industry benchmarks.
5. The growing interest of stakeholders is evident from the surge in partnership activity; clinical trial agreements emerged as the most prevalent partnership model adopted by drug developers.
6. Several investors, having realized the opportunity within this upcoming segment, have invested over USD 11 billion across various funding rounds.
7. More than 345,000 patients have been recruited / enrolled in clinical trials registered for various mRNA-based therapies, across different geographies.
8. Over 430 patents related to mRNA vaccine and therapeutics have been filed / granted by industry and non-industry stakeholders, indicating the growing intellectual capital in this domain.
9. Big pharma players have undertaken several initiatives, ranging from proprietary product development to strategic investments, to tap the lucrative opportunity in this rapidly growing market.
10. The projected opportunity for mRNA vaccine and therapeutics market is likely to be driven by the increasing research and development for mRNA-based drugs focused on non-COVID indications.
MRNA VACCINE AND THERAPEUTICS MARKET: KEY SEGMENTS
Several indications, such as Influenza, Respiratory Syncytial Virus, Cytomegalovirus, are the Expected to Drive the mRNA Vaccine and Therapeutics Market
Based on the application area, the market is segmented into COVID-19 and other indications. Owing to their proven efficacy against the COVID-19 infection, the vaccines and therapeutics developed for COVID-19 infection have captured the majority of the market share. However, the anticipated approval of mRNA vaccines for other indications is likely to drive the market in the coming decade.
Currently, Influenza Segment Occupies the Largest Share of the mRNA Vaccine and Therapeutics Market
Based on the target disease indication, the market is segmented into influenza, respiratory syncytial virus infection and cytomegalovirus diseases. It is worth highlighting that the vaccines and therapeutics developed for influenza are likely to drive the market in the coming decade. This can be attributed to the rise in investment in the research and development of influenza vaccines, along with growing awareness among governments and non-profit organizations about the importance of influenza prevention and control.
North America Accounts for the Largest Share of the Market
Based on key geographical regions, the market is segmented into North America, Europe, Asia-Pacific, Latin America and Rest of the World. It is worth highlighting that the market for North America holds the maximum share of the mRNA vaccines and therapeutics market. This trend is likely to remain the same in the coming decade.
Example Players in the mRNA Vaccine and Therapeutics Market
- Arcturus Therapeutics
- BioNTech
- CureVac
- Ethris
- IMMORNA
- Moderna
- Providence Therapeutics
- RNACure
- Suzhou Abogen Biosciences
- Turn Biotechnologies
- Gennova
- Innovac Therapeutics
- Kernal Biologics
- Pantherna Therapeutics
- pHion Therapeutics
- Recode Therapeutics
- Rejuvenation Technologies
- RNAimmune
- Strand Therapeutics
- Walvax
- Ziphius Vaccines
Primary Research Overview
The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders. The research report features detailed transcripts of interviews held with the following industry stakeholders:
- Business Development Manager, Canvax
- Senior Director, Business Development, eTheRNA
- Team Leader, GC Biopharma
MRNA VACCINE AND THERAPEUTICS MARKET: RESEARCH COVERAGE
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the mRNA vaccine and therapeutics market, focusing on key market segments, including [A] application area, [B] target disease indication and [C] key geographical regions.
- Market Landscape (Drug Therapies): A comprehensive evaluation of mRNA therapeutics and vaccines, considering various parameters, such as [A] phase of development, [B] type of drug candidate, [C] therapeutic area, [D] type of delivery system, [E] type of molecule encoded and [F] route of administration.
- Market Landscape (Drug Developers): A comprehensive evaluation of companies involved in the development of mRNA vaccine and therapeutics, considering various parameters, such as [A] year of establishment, [B] company size (in terms of number of employees), [C] location of headquarters, [D] regional landscape and [E] key players engaged in this domain.
- Company Competitiveness Analysis: A comprehensive competitive analysis of mRNA vaccine and therapeutic developers, examining factors such as [A] developer strength, [B] pipeline strength and [C] number of therapeutic areas targeted.
- Company Profiles: In-depth profiles of key industry players engaged in the development of mRNA vaccine and therapeutics, focusing on [A] company overviews, [B] financial information, [C] mRNA vaccines and therapeutics pipeline, [D] recent developments and [E] an informed future outlook.
- Big Pharma Analysis: A comprehensive examination of various mRNA focused initiatives undertaken by major pharmaceutical companies. It includes a heat map representation that highlights mRNA therapeutics and vaccines under development (in partnership with core mRNA-focused entities), along with information on [A] funding amount raised, [B] partnership activity, and [C] diversity of product portfolio, as well as a spider web representation, comparing the initiatives of big pharmaceutical players on the basis of multiple relevant parameters.
- Start-up Health Indexing: An analysis of the startup companies engaged in this domain based on several relevant parameters, such as [A] number of candidates in discovery, [B] preclinical and clinical phases of development. In addition, it provides details on amount raised, number of investors and number of deals inked.
- Clinical Trial Analysis: Examination of completed, ongoing, and planned clinical studies of various mRNA vaccines and therapeutics based on several relevant parameters, such as [A] trial registration year, [B] trial status, [C] trial phase, [D] therapeutic area, [E] study design, [F] type of sponsor / collaborator, [G] leading industry players (in terms of number of trials conducted), [H] enrolled patient population and [I] geography.
- Partnerships and Collaborations: An analysis of partnerships established in this sector, since 2013, based on several relevant parameters, such as year of partnership, type of partnership, therapeutic area, most active players (in terms of number of deals inked) and regional distribution of partnership activity.
- Funding and Investment Analysis: A detailed evaluation of the investments made in the mRNA vaccines and therapeutics domain, encompassing seed financing, venture capital, IPOs, secondary offerings, debt, grants and other offerings based on several parameters, such as [A] year of funding, [B] type of funding, [C] amount invested, therapeutic area, most active players (in terms of number of funding instances and amount invested) and key investors (in terms of number of funding instances).
- Patent Analysis: Detailed analysis of various patents filed / granted related to mRNA therapeutics and vaccines several relevant parameters, such as [A] type of patent, [B] publication year, [C] geographical region, [D] CPC symbols, [E] leading industry players (in terms of the number of patents filed / granted) and [F] patent valuation.
- Market Impact Analysis: The report analyzes various factors such as drivers, restraints, opportunities, and challenges affecting market growth.
KEY QUESTIONS ANSWERED IN THIS REPORT
- How many companies are currently engaged in this market?
- Which are the leading companies in this market?
- What kind of partnership models are commonly adopted by industry stakeholders?
- What amount has been invested in this domain?
- What factors are likely to influence the evolution of this market?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
REASONS TO BUY THIS REPORT
- The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
- Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
- The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
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