Protein Expression Market: Industry Trends and Global Forecasts, Till 2035

Protein Expression Market: Industry Trends and Global Forecasts, Till 2035



The Protein Expression Market is valued at USD 2.7 billion in 2024 growing at a CAGR of 8% during the forecast period 2024-2035.

Proteins, composed of long chains of amino acids, have become increasingly important in the development of new drugs, treatments, and diagnostic tools. Their versatility, metabolic stability, target specificity, and high affinity have made them attractive candidates for therapeutic applications. In fact, 50% of the top-selling drugs in 2023 are protein-based therapeutics, with over 20 such treatments approved by the US FDA for the treatment of various chronic diseases, including cancers, immune disorders, infections, and diabetes. Furthermore, since 2023, over 6,500 patents related to protein expression have been granted.

The growing demand for protein therapeutics and the need for innovative production methods have driven pharmaceutical companies to adopt protein expression systems for the production of recombinant proteins. These systems offer several advantages, including the ability to produce a wide range of target molecules, higher yields, shorter development times, and lower production costs. Additionally, companies have developed kits and reagents for protein expression, enabling the synthesis of complex proteins, including toxic proteins, membrane proteins, and post-translationally modified proteins.

As the incidence of chronic diseases continues to rise, the demand for protein therapeutics is likely to increase. The maturation of protein-based leads into clinical trials and commercialization, as well as advancements in expression systems, are expected to drive the growth of the protein expression market over the forecast period.



Key Market Segments

Type of Protein Expression System
  • Algal Expression Systems
  • Cell-free Expression Systems
  • Insect Expression Systems
  • Mammalian Expression Systems
  • Prokaryotic Expression Systems
  • Yeast Expression Systems
Protein Expression-related Offerings
  • Competent Cells
  • Expression Vectors
  • Instruments
  • Kits and Reagents
  • Protein Expression Services
Application Area
  • Research and Diagnostics
  • Therapeutics
End Users
  • Academic and Research Institutes
  • CROs and CDMOs
  • Pharmaceutical and Biotechnology Companies
  • Other End-users
Type of Operation
  • In-house Operations
  • Outsourced Operations
Geography
  • North America (US and Canada)
  • Europe (France, Germany, Italy, Spain, UK and Rest of Europe)
  • Asia-Pacific (India, China, Japan, South Korea and Rest of Asia-Pacific)
  • Latin America
  • Middle East and North Africa
Research Coverage:
  • This report provides a comprehensive introduction to protein expression, including its process and various applications. It explores different types of expression systems, their key features, and uses. Additionally, it discusses challenges and recent trends in protein expression, providing insights for researchers and industry professionals.
  • A comprehensive assessment of protein expression product and service providers, along with information on several relevant parameters, such as year of establishment, company size (in terms of employee count) and location of headquarters (region and country), type of protein expression systems (algal, cell-free, insect, mammalian, prokaryotic and yeast expression systems), protein expression-related offerings (competent cells, expression vectors, instruments, kits and reagents and protein expression services) and application areas (industrial, research and therapeutic).
  • This report provides a comprehensive competitiveness analysis of protein expression product and service providers. Key parameters considered include developer strength (company size and experience) and portfolio strength (type of protein expression systems, offerings, and application areas). The report also conducts a benchmarking analysis, highlighting the focus areas of companies and comparing their capabilities among competitors. This analysis provides valuable insights into the strengths and weaknesses of leading protein expression providers, enabling informed decision-making.
  • This report provides in-depth profiles of key companies in the protein expression market. Each profile includes a brief overview, protein expression offerings, financial information, recent developments, and a future outlook. This comprehensive analysis helps readers understand the market dynamics, company strengths, and growth prospects.
  • This report provides an in-depth analysis of the protein expression value chain, including supplier-end user relationships and process stages from design to large-scale production.
  • This report examines the protein expression market's growth drivers, restraints, emerging opportunities, and existing challenges, providing a comprehensive analysis of the factors influencing the market's trajectory.
  • This report provides a detailed estimate of the current market size and future growth potential of the protein expression market from 2024 to 2035. Our analysis is based on adoption trends, secondary and primary research, and reliable data. We have also provided a breakdown of the current and forecasted opportunity within the protein expression industry. To account for future uncertainties, we have developed three forecast scenarios: conservative, base, and optimistic, representing different market growth tracks. These scenarios provide a robust outlook for the market, allowing stakeholders to plan and prepare for various possibilities.
  • Comprehensive prediction of the current and future opportunity within protein expression market across different types of protein expression systems, such as algal, cell-free, insect, mammalian, prokaryotic and yeast expression systems.
  • Detailed predictions of the current and future opportunity within protein expression domain across various protein expression-related offerings, such as competent cells, expression vectors, instruments, kits and reagents and protein expression services.
  • Comprehensive assessment of the current and future opportunity within protein expression industry across various application areas, such as research and diagnostics, and therapeutics.
  • Comprehensive projections of the current and future opportunity within protein expression market across different end-users, such as academic and research institutes, CROs and CDMOs, pharmaceutical and biotechnology companies and other end-users.
  • Comprehensive prediction of the current and future opportunity within the market for protein expression across different types of operation, such as in-house operations and outsourced operations.
  • Comprehensive projections of the current and future opportunity within protein expression market across various geographies, such as North America (US and Canada), Europe (France, Germany, Italy, Spain, UK and Rest of Europe), Asia-Pacific (India, China, Japan, South Korea and Rest of Asia-Pacific), Latin America and Middle East and North Africa.
  • In-depth discussion on the leading protein expression product and service providers in this industry, highlighting their protein expression portfolio and annual revenues of business segment that includes protein expression.
Key Benefits of Buying this Report
  • The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
  • Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
  • The report provides stakeholders with a pulse on the Protein Expression Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Leading Market Companies
  • Agilent Technologies
  • Ajinomoto Bio-Pharma Services
  • Aldevron
  • Cayman Chemical
  • Charles River Laboratories
  • Domainex
  • Eurofins CALIXAR
  • GeNext Genomics
  • GenScript Biotech
  • Lonza
  • Merck KGaA
  • New England Biolabs
  • ProMab
  • Promega
  • ProteoGenix
  • QIAGEN
  • Sartorius
  • Synbio Technologies
  • Syngene
  • Takara Bio
  • Thermo Fisher Scientific
  • WuXi Biologics


1. Preface
1.1. Introduction
1.2. Market Share Insights
1.3. Key Market Insights
1.4. Report Coverage
1.5. Key Questions Answered
1.6. Chapter Outlines
2. Research Methodology
2.1. Chapter Overview
2.2. Research Assumptions
2.3. Project Methodology
2.4. Forecast Methodology
2.5. Robust Quality Control
2.6. Key Market Segmentations
2.7. Key Considerations
2.7.1. Demographics
2.7.2. Economic Factors
2.7.3. Government Regulations
2.7.4. Supply Chain
2.7.5. Covid Impact
2.7.6. Market Access
2.7.7. Healthcare Policies
2.7.8. Industry Consolidation
3. Economic And Other Project Specific Considerations
3.1. Chapter Overview
3.2. Market Dynamics
3.2.1. Time Period
3.2.1.1. Historical Trends
3.2.1.2. Current And Forecasted Estimates
3.2.2. Currency Coverage And Foreign Exchange Rate
3.2.2.1. Major Currencies Affecting The Market
3.2.2.2. Factors Affecting Currency Fluctuations And Foreign Exchange Rates
3.2.2.3. Impact Of Foreign Exchange Rate Volatility On Market
3.2.2.4. Strategies For Mitigating Foreign Exchange Risk
3.2.3. Trade Policies
3.2.3.1. Impact Of Trade Barriers On The Market
3.2.3.2. Strategies For Mitigating The Risks Associated With Trade Barriers
3.2.4. Recession
3.2.4.1. Historical Analysis Of Past Recessions And Lessons Learnt
3.2.4.2. Assessment Of Current Economic Conditions And Potential Impact On The Market
3.2.5. Inflation
3.2.5.1. Measurement And Analysis Of Inflationary Pressures In The Economy
3.2.5.2. Potential Impact Of Inflation On The Market Evolution
4. Executive Summary
5. Introduction
5.1. An Overview Of Protein Expression
5.2. Schematic Representation Of Protein Expression Process
5.3. Applications Of Protein Expression
5.4. Types Of Protein Expression Systems
5.5. Challenges In Protein Expression
5.6. Recent Trends
6. Market Landscape: Key Protein Expression Providers
6.1. Key Protein Expression Providers: Overall Market Landscape
6.1.1. Analysis By Year Of Establishment
6.1.2. Analysis By Company Size
6.1.3. Analysis By Location Of Headquarters (Region)
6.1.4. Analysis By Location Of Headquarters (Country)
6.1.5. Analysis By Type Of Protein Expression System
6.1.6. Analysis By Protein Expression-related Offerings
6.1.7. Analysis By Application Area
7. Company Competitiveness Analysis: Key Protein Expression Providers
7.1. Key Parameters And Methodology
7.2. Company Competitiveness Analysis: Protein Expression Providers:
7.3. Protein Expression Providers: Benchmarking Analysis Of Key Players
7.3.1. Spider Web Analysis: Benchmarking Of Key Players
7.3.1.1. Agilent Technologies
7.3.1.2. Ajinomoto Bio-pharma Services
7.3.1.3. Charles River Laboratories
7.3.1.4. Genscript Biotech
7.3.1.5. Lonza
7.3.1.6. Merck
7.3.1.7. Qiagen
7.3.1.8. Sartorius
7.3.1.9. Thermo Fisher Scientific
7.3.1.10. Wuxi Biologics
7.3.2. Protein Expression Providers: Parameter-wise Benchmarking
7.3.2.1. By Years Of Experience
7.3.2.2. By Company Size
7.3.2.3. By Annual Revenues
7.3.2.4. By Type Of Protein Expression System
7.3.2.5. By Number Of Protein Expression-related Offerings
7.3.2.6. By Number Of Application Areas
8. Company Profiles
8.1. Agilent Technologies
8.1.1. Company Details
8.1.2. Protein Expression-related Offerings
8.1.3. Financial Details
8.1.4. Recent Developments And Future Outlook
8.2. Ajinomoto Bio-pharma Services
8.2.1. Company Details
8.2.2. Protein Expression-related Offerings
8.2.3. Financial Details
8.2.4. Recent Developments And Future Outlook
8.3. Charles River Laboratories
8.3.1. Company Details
8.3.2. Protein Expression-related Offerings
8.3.3. Financial Details
8.3.4. Recent Developments And Future Outlook
8.4. Genscript Biotech
8.4.1. Company Details
8.4.2. Protein Expression-related Offerings
8.4.3. Financial Details
8.4.4. Recent Developments And Future Outlook
8.5. Lonza
8.5.1. Company Details
8.5.2. Protein Expression-related Offerings
8.5.3. Financial Details
8.5.4. Recent Developments And Future Outlook
8.6. Merck
8.6.1. Company Details
8.6.2. Protein Expression-related Offerings
8.6.3. Financial Details
8.6.4. Recent Developments And Future Outlook
8.7. Qiagen
8.7.1. Company Details
8.7.2. Protein Expression-related Offerings
8.7.3. Financial Details
8.7.4. Recent Developments And Future Outlook
8.8. Sartorius
8.8.1. Company Details
8.8.2. Protein Expression-related Offerings
8.8.3. Financial Details
8.8.4. Recent Developments And Future Outlook
8.9. Thermo Fisher Scientific
8.9.1. Company Details
8.9.2. Protein Expression-related Offerings
8.9.3. Financial Details
8.9.4. Recent Developments And Future Outlook
8.10. Wuxi Biologics
8.10.1. Company Details
8.10.2. Protein Expression-related Offerings
8.10.3. Financial Details
8.10.4. Recent Developments And Future Outlook
8.11. Other Prominent Players
8.11.1. Aldevron
8.11.1.1. Company Details
8.11.1.2. Protein Expression-related Offerings
8.11.2. Cayman Chemical
8.11.2.1. Company Details
8.11.2.2. Protein Expression-related Offerings
8.11.3. Domainex
8.11.3.1. Company Details
8.11.3.2. Protein Expression-related Offerings
8.11.4. Eurofins Calixar
8.11.4.1. Company Details
8.11.4.2. Protein Expression-related Offerings
8.11.5. Genext Genomics
8.11.5.1. Company Details
8.11.5.2. Protein Expression-related Offerings
8.11.6. New England Biolabs
8.11.6.1. Company Details
8.11.6.2. Protein Expression-related Offerings
8.11.7. Promab Biotechnologies
8.11.7.1. Company Details
8.11.7.2. Protein Expression-related Offerings
8.11.8. Promega
8.11.8.1. Company Details
8.11.8.2. Protein Expression-related Offerings
8.11.9. Proteogenix
8.11.9.1. Company Details
8.11.9.2. Protein Expression-related Offerings
8.11.10. Synbio Technologies
8.11.10.1. Company Details
8.11.10.2. Protein Expression-related Offerings
8.11.11. Syngene
8.11.11.1. Company Details
8.11.11.2. Protein Expression-related Offerings
8.11.12. Takara Bio
8.11.12.1. Company Details
8.11.12.2. Protein Expression-related Offerings
9. Value Chain Analysis
9.1. Brief Overview On Protein Expression Process And Stakeholders Involved
9.2. Schematic Representation Of Protein Expression From Design To Large Scale Production
10. Market Impact Analysis: Drivers, Restraints, Opportunities And Challenges
10.1. Market Drivers
10.2. Market Restraints
10.3. Market Opportunities
10.4. Market Challenges
11. Global Protein Expression Market
11.1. Key Assumptions And Methodology
11.2. Global Protein Expression Market, Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
11.2.1. Scenario Analysis
11.2.1.1. Conservative Scenario
11.2.1.2. Optimistic Scenario
12. Protein Expression Market, By Type Of Protein Expression System
12.1. Key Assumptions And Methodology
12.2. Protein Expression Market: Distribution By Type Of Protein Expression System, 2020, 2024 And 2035
12.2.1. Mammalian Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
12.2.2. Prokaryotic Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
12.2.3. Yeast Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
12.2.4. Insect Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
12.2.5. Cell-free Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
12.2.6. Algal Expression System: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
13. Protein Expression Market, By Protein Expression-related Offerings
13.1. Key Assumptions And Methodology
13.2. Protein Expression Market: Distribution By Protein Expression-related Offerings, 2020, 2024 And 2035
13.2.1. Kits And Reagents: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
13.2.2. Protein Expression Services: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
13.2.3. Instruments: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
13.2.4. Competent Cells: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
13.2.5. Expression Vectors: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
14. Protein Expression Market, By Application Area
14.1. Key Assumptions And Methodology
14.2. Protein Expression Market: Distribution By Application Area, 2020, 2024 And 2035
14.2.1. Therapeutics: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
14.2.2. Research And Diagnostics: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
15. Protein Expression Market, By End-users
15.1. Key Assumptions And Methodology
15.2. Protein Expression Market: Distribution By Type Of End-user, 2020, 2024 And 2035
15.2.1. Pharmaceutical And Biotechnology Companies: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
15.2.2. Cros And Cdmos: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
15.2.3. Academic And Research Institutes: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
15.2.4. Other End-users: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
16. Protein Expression Market, By Type Of Operation
16.1. Key Assumptions And Methodology
16.2. Protein Expression Market: Distribution By Type Of Operation, 2020, 2024 And 2035
16.2.1. In-house Operations: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
16.2.2. Outsourced Operations: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17. Protein Expression Market, By Geography
17.1. Key Assumptions And Methodology
17.2. Protein Expression Market: Distribution By Geography, 2020, 2024 And 2035
17.2.1. North America: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.1.1. Us: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.1.2. Canada: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2. Europe: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.1. Germany: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.2. France: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.3. Italy: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.4. Uk: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.5. Spain: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.2.6. Rest Of Europe: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3. Asia-pacific: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3.1. China: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3.2. Japan: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3.3. South Korea: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3.4. India: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.3.5. Rest Of Asia-pacific: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
17.2.4. Latin America: Historical Trends (2020-2023) And Future Estimates (2024-2035)
17.2.5. Middle East And North Africa: Historical Trends (2020-2023) And Forecasted Estimates (2024-2035)
18. Protein Expression Market, By Key Players
18.1. Agilent Technologies
18.2. Ajinomoto Bio-pharma Services
18.3. Charles River Laboratories
18.4. Genscript Biotech
18.5. Lonza
18.6. Merck
18.7. Qiagen
18.8. Sartorius
18.9. Thermo Fisher Scientific
18.10. Wuxi Biologics
19. Executive Insights
20 Appendix 1: Tabulated Data
21 Appendix 2: List Of Companies And Organizations

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