Peptide Synthesis Market by Type of Peptide Synthesis Method (Chemical Synthesis and Non-Chemical Synthesis), Type of Chemical Synthesis (Solid Phase Peptide Synthesis, Liquid Phase Peptide Synthesis and Hybrid Phase Peptide Synthesis), Contract Manufactu

Peptide Synthesis Market by Type of Peptide Synthesis Method (Chemical Synthesis and Non-Chemical Synthesis), Type of Chemical Synthesis (Solid Phase Peptide Synthesis, Liquid Phase Peptide Synthesis and Hybrid Phase Peptide Synthesis), Contract Manufacturing Organization Size (Small, Mid-sized, and Large Companies), Key Geographical Regions (North America, Europe, and Asia-Pacific and Rest of the World): Industry Trends and Global Forecasts, Till 2035

Peptide Synthesis Market: Overview

As per Roots Analysis, the global peptide synthesis market is estimated to grow from USD 2.8 billion in the current year to USD 5.1 billion by 2035, at a CAGR of 5.5% during the forecast period, till 2035.

The market sizing and opportunity analysis has been segmented across the following parameters:

Type of Synthesis Method Used

• Chemical Synthesis Method
• Non-Chemical Synthesis Method

Type of Chemical Synthesis Method

• Liquid Phase Peptide Synthesis
• Solid Phase Peptide Synthesis
• Hybrid Phase Peptide Synthesis

Company (CMO) Size

• Small
• Mid-sized
• Large

Key Geographical Regions

• North America
• Europe
• Asia-Pacific and Rest of the World

PEPTIDE SYNTHESIS MARKET: GROWTH AND TRENDS

Owing to enhanced metabolic stability, higher affinity, and biological target specificity, peptide therapeutics have emerged as a promising modality in the past few years. It is worth highlighting that more than 80 peptide programs have been approved by different regulatory agencies across the globe. In addition, more than 630 clinical trials are currently evaluating several peptide therapeutics for the treatment of a wide range of diseases. This demonstrates the extensive development efforts being undertaken by various stakeholders in this domain. However, peptide synthesis is associated with several challenges that have prompted pharmaceutical and biotechnology companies to outsource key operations. At present, over 75 industry players are offering a wide range of peptide synthesis services, including formulation development, large scale production, analytical / regulatory support, process development, validation batches, packaging and labeling, pre-formulation and custom peptide synthesis.

As drug developers invest more in these innovative therapies, the peptide synthesis market is anticipated to expand further. Moreover, owing to the healthy early-stage pipeline, growth in this domain is expected to continue in the long term as well.

PEPTIDE SYNTHESIS MARKET: KEY INSIGHTS

The report delves into the current state of the peptide synthesis market and identifies potential growth opportunities within the industry. Some key findings from the report include:

1. Currently, over 75 companies claim to offer peptide therapeutics contract API manufacturing services in order to cater to the rising demand for peptide API based drugs, across the globe.

2. The market landscape is highly fragmented, featuring the presence of both new entrants and established players in different geographical regions; close to 50% of such contract manufacturers are large companies.

3. Majority of players offer generic peptide API manufacturing using the chemical synthesis method; further, 60% of the peptide synthesis service providers offer API manufacturing with more than one type of peptide synthesis method.

4. In pursuit of gaining a competitive edge, peptide therapeutics contract API manufacturers are actively upgrading their existing capabilities and enhancing their service portfolios to establish a strong foothold in the domain.

5. The growing interest of developers in peptide-based therapeutics is evident from the rise in partnership activity; more than 30% of the deals were inked specifically for peptide API manufacturing.

6. In order to meet the rising demand for peptide APIs, service providers have made elaborate investments to expand their existing capacities and capabilities; this trend is most pronounced in Germany and the US.

7. In the last decade, over 600 clinical trials, enrolling close to 200 thousand patients suffering from a myriad of disease indications, have been registered across the globe to evaluate the efficacy of peptide-based drugs.

8. Since peptide-based drugs are being used progressively for the treatment of various diseases, the demand is indubitably rising and expected to grow at an annualized rate of over 7% in the near future.

9. The global installed peptide manufacturing capacity is spread across various geographies; majority of the capacity is installed in the production plants located in Asia-Pacific and Europe.

10. The projected opportunity for peptide therapeutics contract service providers is likely to be well distributed across different segments; currently, close to 40% of the contract manufacturing opportunity is captured by Europe.

PEPTIDE SYNTHESIS MARKET: KEY SEGMENTS

Currently, the Chemical Synthesis Method Occupies the Largest Share of the Peptide Synthesis Market

Based on the types of peptide synthesis methods, the global peptide synthesis market is segmented into chemical synthesis method and non-chemical synthesis method. It is worth highlighting that, owing to several benefits, such as flexibility, scalability, ease of implementation and cost-effectiveness, majority of the current peptide synthesis market is captured by the chemical synthesis method. This trend is likely to remain the same in the forthcoming years.

Currently, Solid Phase Peptide Synthesis Occupies the Largest Share of the Peptide Synthesis Market

Based on the type of chemical synthesis method, the global peptide synthesis market is segmented into solid phase peptide synthesis, liquid phase peptide synthesis, and hybrid phase peptide synthesis. It is worth highlighting that the solid phase peptide synthesis market is likely to witness substantial growth in the coming decade. This can be attributed to the fact that the solid phase peptide synthesis method offers numerous advantages, such as rapid formation of linear peptides, simple purification and cost-effectiveness.

Small Contract Manufacturers Segment is the Fastest Growing Segment of the Peptide Synthesis Market

Based on the company size, the peptide synthesis market is segmented into small, mid-sized, and large contract manufacturers. It is anticipated that small contract manufacturers are likely to grow at a higher CAGR in the forthcoming years.

Europe Accounts for the Largest Share of the Market

Based on key geographical regions, the market is segmented into North America, Europe, and Asia-Pacific and the rest of the world. Majority of the share is expected to be captured by players based in Europe. It is worth highlighting that over the years, the market in Asia-Pacific and the rest of the world is expected to grow at a higher CAGR.

Example Players in the Peptide Synthesis Market

• AmbioPharm
• CPC Scientific
• Creative Peptides
• CSBio
• Bachem
• BCN Peptide
• CordenPharma
• Senn Chemicals
• PolyPeptide
• Auspep
• Chinese Peptide Company
• Hybio Pharmaceuticals
• Peptide Institute
• ScinoPharm

Primary Research Overview

The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders. The research report features detailed transcripts of interviews held with the following industry stakeholders:

• Chief Business Officer, Senior Director of Scientific Affairs and Technical Marketing, Ascendia Pharmaceuticals
• Vice President, Peptides, Almac
• Chief Financial Officer, NUMAFERM
• Senior Manager, Peptide Business Project Leader, Sekisui XenoTech
• Founder and Owner, Previtalica

PEPTIDE SYNTHESIS MARKET: RESEARCH COVERAGE

• Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the peptide synthesis market, focusing on key market segments, including [A] type of peptide synthesis method, [B] type of chemical synthesis, [C] contract manufacturing organization size and [D] key geographical regions.
• Market Landscape: A comprehensive evaluation of companies involved in peptide contract manufacturing, considering various parameters, such as [A] year of establishment, [B] year of entrance, [C] company (CMO) size (in terms of number of employees), [D] location of headquarters, [E] type of product, [F] type of API manufactured, [G] scale of operation, [H] type of services offered, [I] peptide synthesis method, [J] type of peptide modification, [K] type of purification technology used, [L] regulatory certifications and accreditations, [M] geographical presence and [N] location of peptide API manufacturing facilities.
• Company Competitiveness Analysis: A comprehensive competitive analysis of peptide contract manufacturers, examining factors such as [A] supplier strength, [B] company competitiveness and [C] number of peptide modification services offered.
• Company Profiles: In-depth profiles of key industry players engaged in the peptide therapeutics contract manufacturing market, focusing on [A] company overviews, [B] service portfolio, [C] location of production facilities and capabilities of service providers, [D] recent developments, and [E] an informed future outlook.
• Recent Developments and Initiatives: An analysis of recent trends, covering partnerships and collaborations, and expansion initiatives held in this domain.
• Clinical Trial Analysis: Examination of completed, ongoing, and planned clinical studies of various peptide therapeutics based on several relevant parameters, such as [A] trial registration year, [B] number of patients enrolled, [C] trial phase, [D] trial status, [E] study design, [F] type of sponsor / collaborator, [G] therapeutic area, [H] type of mechanism of action and clinical trial centers, [I] geography, and [J] enrolled patient population.
• Regional Capability Analysis: A detailed analysis on the capabilities of peptide synthesis companies in different regions, based on several relevant parameters, such as the number of CMOs, number of clinical sites, number of clinical trials, number of patients enrolled, number of peptide manufacturing facilities, demand for peptide therapeutics and installed capacity.
• Demand Analysis: Informed estimates of the annual commercial and clinical demand for peptide therapeutics based on several relevant parameters, such as [A] target patient population, [B] dosing frequency and [C] dose strength.
• Capacity Analysis: The report provides an estimation of the global annual capacity of contract manufacturers in the peptide synthesis market. The analysis takes into consideration the distribution of available peptide production capacity across [A] companies of different sizes, [B] scale of operation, [C] location of manufacturing facility and [D] synthesis method.
• Likely Partner Analysis: An analysis highlighting potential strategic partners segregated based on the likelihood of entering into collaboration with peptide therapeutics developers. These players have been shortlisted based on several relevant parameters, such as [A] pipeline strength, [B] pipeline maturity, [C] year of establishment and [D] company size.
• Additional Insights: An insightful framework that emphasizes the key indicators and factors that need to be considered by developers to determine whether to manufacture their respective products in-house or outsource the manufacturing operation to contract service providers.
• Total Cost of Ownership: A region-wise, detailed analysis of the total cost of ownership for a peptide contract manufacturing service provider. It features an informed estimate of direct and indirect expenses taking into consideration 10 relevant parameters, over a span of 20 years.
• Regulatory Landscape: A discussion on general regulatory guidelines, highlighting the key differences across various geographies, including the US, Europe, Australia, China, India, Japan and South Korea. In addition, it provides details related to the various challenges, related to regulatory scrutiny, faced by peptide synthesis companies.
• SWOT Analysis: A SWOT analysis, focusing on key drivers and challenges that are likely to impact the industry’s evolution. Further, it includes a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall industry.

KEY QUESTIONS ANSWERED IN THIS REPORT

• How many companies are currently engaged in this market?
• Which are the leading companies in this market?
• What kind of partnership models are commonly adopted by industry stakeholders?
• What is the current annual demand for peptide therapeutics?
• What factors are likely to influence the evolution of this market?
• What is the current and future market size?
• What is the CAGR of this market?
• How is the current and future market opportunity likely to be distributed across key market segments?

REASONS TO BUY THIS REPORT

• The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
• Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
• The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.

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