Lyophilization Services Market for Biopharmaceuticals (2nd Edition), 2022-2035


Over the last decade, a steady rise has been observed in the annual number of approvals for various types of biologics (including monoclonal antibodies, cell therapies, recombinant proteins, vaccines and gene therapies). In addition, more than 8,000 biological therapeutics are currently being evaluated in clinical trials, being conducted across the globe. Evidently, biologics have emerged as one of the fastest growing segments in the pharmaceutical industry. Driven by several advantages offered by biologics over small molecules (including high efficacy, target specificity and favorable safety profiles), the biopharmaceutical market is anticipated to witness continued and consistent growth over the next several years. However, there are a variety of challenges associated with such therapies. For instance, biological drugs are inherently less stable as compared to small molecules and, therefore, more prone to physical and chemical degradation. In order to achieve longer and commercially viable shelf lives, players are actively adopting the lyophilization (also known as freeze-drying) technique; it enables the production of dry stable biopharmaceutical formulations. , In this context, it is worth highlighting that around 50% of the currently approved biopharmaceuticals are injectables. Of these, about one third of the drug candidates are being lyophilized.

Setting up in-house lyophilization capabilities and operations is an expensive and time-consuming process, which requires specialized lyophilization equipment and expertise. Considering the high capital investment and technical / routine operations-related challenges associated with lyophilization of biopharmaceuticals, a growing number of biologic developers are outsourcing their lyophilization operations to qualified contract manufacturing organizations (CMOs) in order to leverage their capabilities and yield cost savings opportunities. , , , Presently, more than 105 contract manufacturers claim to have the required capabilities to offer lyophilization services for biotherapeutics. In addition, lyophilization service providers are entering into strategic alliances in order to consolidate their presence in this field and enhance existing capabilities to meet the growing demand for biologics. Driven by the increasing preference for outsourcing, continuous growth of the biological therapeutics pipeline and a steady rise in drug approvals, the lyophilization services market for biopharmaceuticals is likely to witness steady growth in the foreseen future.

SCOPE OF THE REPORT

The “Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized (Antibodies, Cell and Gene Therapies, Vaccines and Other Biologics), Type of Primary Packaging System (Vials, Syringes, Cartridges, Ampoules and Others) and Key Geographies (North America, Europe, Asia Pacific, Latin America, Middle East and North Africa, and Rest of the World) – Industry Trends and Global Forecasts, 2022-2035” report features an extensive study of companies engaged in offering lyophilization services for biopharmaceuticals. The study features an in-depth analysis of the key drivers and trends related to this domain. Amongst other elements, the report includes:

  • A detailed assessment of the current landscape of companies offering lyophilization services for biopharmaceuticals, along with information on their year of establishment, company size (in terms of employee count), location of headquarters, scale of operation (preclinical, clinical and commercial), regulatory certification / accreditation, type of biologic lyophilized (proteins, antibodies, vaccines, nucleic acids, cell / gene therapies, others and biologics (unspecified)), process of lyophilization (bulk lyophilization and individual lyophilization), type of primary packaging system (vials, pre-filled syringes, cartridges, ampoules and others) and additional services offered by the firms (lyophilization cycle development and lyophilization cycle optimization).
  • An insightful benchmark analysis of various service providers segregated into three peer groups based on location of their headquarters (North America, Europe, and Asia Pacific and RoW). The companies were further distributed across key geographies, based on their employee count, into three categories, namely small (1-200 employees), mid-sized (201-500 employees) and large / very large (>500 employees), highlighting the top players in this domain, based on their respective capabilities.
  • Elaborate profiles of prominent players offering lyophilization services for biopharmaceuticals, based in North America, Europe and Asia Pacific. Each profile features a brief overview of the company, details related to lyophilization service offerings for biopharmaceuticals, dedicated facilities, recent developments and an informed future outlook.
  • An analysis of the partnerships that have been inked by stakeholders engaged in this domain, covering acquisitions, asset acquisitions, product / technology development agreements, and other related agreements. Further, the partnership activity in this domain has been analyzed based on various parameters, such as year of partnership, most active players (in terms of number of partnerships) and regional distribution of the collaborations.
  • A detailed analysis of the recent expansions undertaken by various lyophilization service providers for biopharmaceuticals, based on several relevant parameters, such as year of expansion, type of expansion (capacity expansions, facility expansions and new facility addition), company size (small, mid-sized, large and very large companies), location of headquarters, location of expanded facility, most active players (in terms of number of recent expansions) and geographical distribution.
  • A survey analysis presenting additional insights on lyophilization services offered for biopharmaceuticals, apart from those mentioned on the service provider’s website. Inputs for this chapter were gathered across key parameters, including type of biologic lyophilized, type of primary packaging system, scale of operation, availability of lyophilization cycle development / optimization capabilities and location of dedicated manufacturing facility for lyophilization. Additionally, through the questionnaire we obtained some insights on the likely size of the current market for lyophilization services for biopharmaceuticals.
  • A case study on lyophilization cycle development and optimization services, highlighting the important parameters and techniques required for these processes. Further, the chapter presents the list of players that provide such services for biopharmaceuticals.
  • A case study on alternative approaches to the lyophilization process, such as spray drying, spray freeze drying, atmospheric spray freeze drying and vacuum foam drying.
  • One of the key objectives of the report was to estimate the existing market size and identify potential growth opportunities for lyophilization services market for biopharmaceuticals over the coming decade. We have provided an informed estimate on the likely evolution of the market over the period 2022-2035. The report features a detailed forecast of the overall lyophilization services market for biopharmaceuticals, wherein both the current and upcoming opportunity is segmented across [A] type of biologic lyophilized (antibodies, cell and gene therapies, vaccines and other biologics), [B] type of primary packaging system (vials, syringes, cartridges, ampoules and others) and [C] key geographies (North America, Europe, Asia Pacific, Middle East and North Africa, Latin America and Rest of the world). In order to account for future uncertainties and add robustness to our model, we have provided three market forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry’s growth.

    The opinions and insights presented in the report were also influenced by discussions held with senior stakeholders in the industry. The report features detailed transcripts of interviews held with the following individuals:
  • Brian Sasaki (Director of Business Development) and Thomas Ingallinera (Vice President of Technical Support), Pharmaceutical International
  • Doreen Coull (Regional Sales Director, Curia)
  • Patrick DePalma (Former Director of CMO Business Development, BioDefense Division, Emergent BioSolutions)
  • Rocio Gonzalez Rodriguez (Head of CDMO Project Management, Liof Pharma)
  • John Shaw (Former Head of Business Development and Marketing, Vibalogics)
  • Sophia Kim (Commercial DP (Depository Participant) Sales / Group Leader, Samsung Biologics)
  • Marianna Tcherpakov (Business Development Manager, Bioserv)
  • Adam Inche (Marketing Manager, Symbiosis Pharmaceutical Services)
  • Adam Viverette (Lyophilization Manager, Patheon)
  • Steven Nail (Principal Scientist, Baxter BioPharma Solutions)
  • MARKET SEGMENTATIONS

    Lyophilization Services for Biopharmaceuticals: Market Segmentations

    Market Segments Details

    Forecast Period 2022 - 2035

    Type of Biologic Lyophilized
  • Antibodies
  • Cell and Gene Therapies
  • Vaccines
  • Other Biologics
  • Type of Primary Packaging System
  • Vials
  • Syringes
  • Cartridges
  • Ampoules
  • Others
  • Key Geographical Regions
  • North America
  • Europe
  • Asia Pacific
  • MENA
  • Latin America
  • Rest of the World
  • Source: Roots Analysis

    RESEARCH METHODOLOGY

    The data presented in this report has been gathered via secondary and primary research. For all our projects, we conduct interviews / surveys with experts in this domain (academia, industry, medical practice and other associations) to solicit their opinions on emerging trends in the market. This is primarily useful for us to draw out our own opinion on how the market will evolve across different regions and technology segments. Wherever possible, the available data has been checked for accuracy from multiple sources of information.

    The secondary sources of information include
  • Annual reports
  • Investor presentations
  • SEC filings
  • Industry databases
  • News releases from company websites
  • Government policy documents
  • Industry analysts’ views
  • All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

    KEY QUESTIONS ANSWERED
  • Who are the key players engaged in offering lyophilization services for biopharmaceuticals?
  • What is the relative competitiveness of lyophilization service providers for biopharmaceuticals?
  • What type of partnership models are commonly adopted by stakeholders in this industry?
  • What are the different types of expansion initiatives being undertaken by lyophilization service providers for biopharmaceuticals?
  • What are the key market trends and driving factors that are likely to impact this market?
  • How is the current and future market opportunity likely to be distributed across key segments?
  • CHAPTER OUTLINES

    Chapter 2 is an executive summary of the key insights captured in our report. It offers a high-level view of the current state of lyophilization services market for biopharmaceuticals and its likely evolution in the short term, mid-term and long term.

    Chapter 3 provides a general overview of the lyophilization process, its historical evolution, underlying principle, as well as associated advantages and disadvantages. The chapter also lays emphasis on lyophilization of biopharmaceuticals, along with various steps involved in the process. Furthermore, it features an elaborate discussion on the lyophilizer, its components and the primary packaging systems used for storage of the lyophilized formulations. It also presents information on lyophilization cycle development and optimization.

    Chapter 4 features a detailed review of the current market landscape of around 105 companies offering lyophilization services for biopharmaceuticals. Additionally, it features an in-depth analysis of service providers, based on a number of relevant parameters, such as year of establishment, company size (in terms of employee count) and location of headquarters. The chapter also covers details about scale of operation (preclinical, clinical and commercial), regulatory certification / accreditation, type of biologic lyophilized (proteins, antibodies, vaccines, nucleic acids, cell / gene therapies, others and biologics (unspecified)), process of lyophilization (bulk lyophilization and individual lyophilization), type of primary packaging system (vials, pre-filled syringes, cartridges, ampoules and others) and additional services offered by the firms (lyophilization cycle development and lyophilization cycle optimization).

    Chapter 5 presents an insightful benchmark analysis of the lyophilization service providers for biopharmaceuticals, located in North America, Europe, and Asia Pacific and RoW. The companies are further segmented based on their employee count, into three categories, namely small (1-200 employees), mid-sized (201-500 employees) and large / very large (>500 employees) across the key geographies. The analysis compares the service providers on the basis of various parameters, such as number of facilities, scale of operation, number of biologics lyophilized, process of lyophilization and number of primary packaging systems. In the chapter, the top stakeholders in each geography have been plotted on a spider web for their respective capabilities.

    Chapter 6 features detailed profiles of the prominent companies that offer lyophilization services for biopharmaceuticals in North America. Each company profile features a brief overview of the company, details related to lyophilization service offerings for biopharmaceuticals, dedicated facilities, recent developments and an informed future outlook.

    Chapter 7 features detailed profiles of the prominent companies that offer lyophilization services for biopharmaceuticals in Europe. Each company profile features a brief overview of the company, details related to its lyophilization service offerings for biopharmaceuticals, dedicated facilities, recent developments and an informed future outlook.

    Chapter 8 features detailed profiles of the prominent companies that offer lyophilization services for biopharmaceuticals in Asia Pacific. Each company profile features a brief overview of the company, details related to its lyophilization service offerings for biopharmaceuticals, dedicated facilities, recent developments and an informed future outlook.

    Chapter 9 features an elaborate discussion and analysis of the various collaborations and partnerships that have been inked amongst stakeholders in this domain, in the period 2018 – 2021. Further, the partnership activity in this domain has been analyzed based on various parameters, such as year of partnership, type of partnership model (acquisitions, asset acquisitions, product / technology development agreements and others), most active player(s) (in terms of number of partnerships inked) and regional distribution of the collaborations.

    Chapter 10 presents a detailed analysis of the recent expansions undertaken by various lyophilization service providers for biopharmaceuticals, based on several relevant parameters, such as year of expansion, type of expansion (capacity expansions, facility expansions and new facility additions), company size (small, mid-sized, large and very large companies), location of headquarters, location of expanded facility, most active players (in terms of number of recent expansions) and geographical distribution.

    Chapter 11 presents insights from the survey conducted for this study. We approached senior stakeholders from various companies involved in providing lyophilization services for biopharmaceuticals. The questionnaire primarily focused on type of biologic lyophilized, type of primary packaging system, scale of operation, availability of lyophilization cycle development / optimization capabilities and location of dedicated manufacturing facility for lyophilization. This helped us develop a deeper understanding on the nature of their services and the associated commercial potential. Additionally, we obtained some insights on the likely size of the current market of lyophilization services for biopharmaceuticals.

    Chapter 12 presents a comprehensive market forecast analysis, highlighting the future potential of the market till 2035. We have segregated the current and upcoming opportunity based on [A] type of biologic lyophilized (antibodies, cell and gene therapies, vaccines and other biologics), [B] type of primary packaging system (vials, syringes, cartridges, ampoules and others) and [C] key geographies (North America, Europe, Asia Pacific, Middle East and North Africa, Latin America and Rest of the world). It is worth mentioning that we adopted a top-down approach for this analysis, backing our claims with relevant datapoints and credible inputs from primary research.

    Chapter 13 presents elaborate details on lyophilization cycle development and optimization services, highlighting the important parameters and techniques required for these processes and the list of players offering such services for biopharmaceuticals.

    Chapter 14 features a case study on alternative methods to the lyophilization process, such as spray drying, spray freeze drying, atmospheric spray freeze drying and vacuum foam drying. It specifically elaborates spray drying, covering information such as step-wise approach, applications of spray drying for biopharmaceuticals, key players providing such services and an informed comparison with lyophilization.

    Chapter 15 summarizes the overall report. In this chapter, we have provided a list of key takeaways from the report, and expressed our independent opinion related to the research and analysis described in the previous chapters.

    Chapter 16 is a collection of interview transcripts of the discussions held with key stakeholders in this market. In this chapter, we have presented the details of interview held with Brian Sasaki (Director of Business Development) and Thomas Ingallinera (Vice President of Technical Support), Pharmaceutical International, Doreen Coull (Regional Sales Director, Curia), Patrick DePalma (Former Director of CMO Business Development, BioDefense Division, Emergent BioSolutions), Rocio Gonzalez Rodriguez (Head of CDMO Project Management, Liof Pharma), John Shaw (Former Head of Business Development and Marketing, Vibalogics), Sophia Kim (Commercial DP (Depository Participant) Sales / Group Leader, Samsung Biologics), Marianna Tcherpakov (Business Development Manager, Bioserv), Adam Inche (Marketing Manager, Symbiosis Pharmaceutical Services), Adam Viverette (Lyophilization Manager, Patheon) and Steven Nail (Principal Scientist, Baxter BioPharma Solutions).

    Chapter 17 is an appendix, which provides tabulated data and numbers for all the figures provided in the report.

    Chapter 18 is an appendix, which contains the list of companies and organizations mentioned in the report.


    1. PREFACE
    1.1. Scope of the Report
    1.2. Research Methodology
    1.3. Key Questions Answered
    1.4. Chapter Outlines
    2. EXECUTIVE SUMMARY
    3. INTRODUCTION
    3.1. Chapter Overview
    3.2. Overview of Lyophilization
    3.2.1. Historical Evolution
    3.2.2. Underlying Principles
    3.2.3. Advantages and Disadvantages
    3.3. Lyophilization of Biopharmaceuticals
    3.3.1. Need for Lyophilization of Biopharmaceuticals
    3.3.2. Lyophilization Process
    3.3.2.1. Formulation and Filling
    3.3.2.2. Freezing
    3.3.2.3. Primary Drying
    3.3.2.4. Secondary Drying
    3.4. Lyophilizer and its Key Components
    3.5. Primary Packaging Systems Used for Lyophilization of Biopharmaceuticals
    3.6. Lyophilization Cycle Development and Optimization
    3.7. Concluding Remarks
    4. MARKET LANDSCAPE
    4.1. Chapter Overview
    4.2. Lyophilization Service Providers for Biopharmaceuticals: Overall Market Landscape
    4.2.1. Analysis by Year of Establishment
    4.2.2. Analysis by Company Size
    4.2.3. Analysis by Location of Headquarters
    4.2.4. Analysis by Scale of Operation
    4.2.5. Analysis by Regulatory Certification / Accreditation
    4.2.6. Analysis by Type of Biologic Lyophilized
    4.2.7. Analysis by Process of Lyophilization
    4.2.8. Analysis by Type of Primary Packaging System
    4.2.9. Analysis by Additional Services Offered
    5. BENCHMARK ANALYSIS
    5.1. Chapter Overview
    5.2. Methodology
    5.3. Benchmark Analysis: Peer Groups
    5.3.1. Benchmark Analysis: North America (Peer Group I)
    5.3.2. Benchmark Analysis: North America (Peer Group II)
    5.3.3. Benchmark Analysis: North America (Peer Group III)
    5.3.4. Benchmark Analysis: Europe (Peer Group IV)
    5.3.5. Benchmark Analysis: Europe (Peer Group V)
    5.3.6. Benchmark Analysis: Europe (Peer Group VI)
    5.3.7. Benchmark Analysis: Asia Pacific and Rest of the World (Peer Group VII)
    5.3.8. Benchmark Analysis: Asia Pacific and Rest of the World (Peer Group VIII)
    6. COMPANY PROFILES: LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS IN NORTH AMERICA
    6.1. Chapter Overview
    6.2. Baxter BioPharma Solutions
    6.2.1. Company Overview
    6.2.2. Lyophilization Service Offerings for Biopharmaceuticals
    6.2.3. Dedicated Biopharmaceutical Lyophilization Facilities
    6.2.4. Recent Developments and Future Outlook
    6.3. Curia
    6.3.1. Company Overview
    6.3.2. Lyophilization Service Offerings for Biopharmaceuticals
    6.3.3. Dedicated Biopharmaceutical Lyophilization Facilities
    6.3.4. Recent Developments and Future Outlook
    6.4. Emergent BioSolutions
    6.4.1. Company Overview
    6.4.2. Lyophilization Service Offerings for Biopharmaceuticals
    6.4.3. Dedicated Biopharmaceutical Lyophilization Facilities
    6.4.4. Recent Developments and Future Outlook
    6.5. LSNE Contract Manufacturing
    6.5.1. Company Overview
    6.5.2. Lyophilization Service Offerings for Biopharmaceuticals
    6.5.3. Dedicated Biopharmaceutical Lyophilization Facilities
    6.5.4. Recent Developments and Future Outlook
    6.6. Lyophilization Technology
    6.6.1. Company Overview
    6.6.2. Lyophilization Service Offerings for Biopharmaceuticals
    6.6.3. Dedicated Biopharmaceutical Lyophilization Facilities
    6.6.4. Recent Developments and Future Outlook
    7. COMPANY PROFILES: LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS IN EUROPE
    7.1. Chapter Overview
    7.2. CordenPharma
    7.2.1. Company Overview
    7.2.2. Lyophilization Service Offerings for Biopharmaceuticals
    7.2.3. Dedicated Biopharmaceutical Lyophilization Facilities
    7.2.4. Recent Developments and Future Outlook
    7.3. Coriolis Pharma
    7.3.1. Company Overview
    7.3.2. Lyophilization Service Offerings for Biopharmaceuticals
    7.3.3. Dedicated Biopharmaceutical Lyophilization Facilities
    7.3.4. Recent Developments and Future Outlook
    7.4. Northway Biotech
    7.4.1. Company Overview
    7.4.2. Lyophilization Service Offerings for Biopharmaceuticals
    7.4.3. Dedicated Biopharmaceutical Lyophilization Facilities
    7.4.4. Recent Developments and Future Outlook
    7.5. ProJect Pharmaceutics
    7.5.1. Company Overview
    7.5.2. Lyophilization Service Offerings for Biopharmaceuticals
    7.5.3. Dedicated Biopharmaceutical Lyophilization Facilities
    7.5.4. Recent Developments and Future Outlook
    7.6. Vetter Pharma
    7.6.1. Company Overview
    7.6.2. Lyophilization Service Offerings for Biopharmaceuticals
    7.6.3. Dedicated Biopharmaceutical Lyophilization Facilities
    7.6.4. Recent Developments and Future Outlook
    8. COMPANY PROFILES: LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS IN ASIA PACIFIC
    8.1. Chapter Overview
    8.2. BioZed Engineering
    8.2.1. Company Overview
    8.2.2. Lyophilization Service Offerings for Biopharmaceuticals
    8.2.3. Dedicated Biopharmaceutical Lyophilization Facilities
    8.2.4. Recent Developments and Future Outlook
    8.3. CinnaGen
    8.3.1. Company Overview
    8.3.2. Lyophilization Service Offerings for Biopharmaceuticals
    8.3.3. Dedicated Biopharmaceutical Lyophilization Facilities
    8.3.4. Recent Developments and Future Outlook
    8.4. MabPlex
    8.4.1. Company Overview
    8.4.2. Lyophilization Service Offerings for Biopharmaceuticals
    8.4.3. Dedicated Biopharmaceutical Lyophilization Facilities
    8.4.4. Recent Developments and Future Outlook
    8.5. Samsung Biologics
    8.5.1. Company Overview
    8.5.2. Lyophilization Service Offerings for Biopharmaceuticals
    8.5.3. Dedicated Biopharmaceutical Lyophilization Facilities
    8.5.4. Recent Developments and Future Outlook
    8.6. WuXi Biologics
    8.6.1. Company Overview
    8.6.2. Lyophilization Service Offerings for Biopharmaceuticals
    8.6.3. Dedicated Biopharmaceutical Lyophilization Facilities
    8.6.4. Recent Developments and Future Outlook
    9. PARTNERSHIPS AND COLLABORATIONS
    9.1. Chapter Overview
    9.2. Partnership Models
    9.3. Lyophilization Services for Biopharmaceuticals: List of Partnerships and Collaborations
    9.3.1. Analysis by Year of Partnership
    9.3.2. Analysis by Type of Partnership
    9.3.3. Analysis by Year and Type of Partnership
    9.3.4. Most Active Players: Analysis by Number of Partnerships
    9.3.5. Analysis by Geography
    9.3.5.1. Intercontinental and Intracontinental Deals
    9.3.5.2. International and Local Deals
    10. RECENT EXPANSIONS
    10.1. Chapter Overview
    10.2. Lyophilization Services Market for Biopharmaceuticals: List of Recent Expansions
    10.2.1. Analysis by Year of Expansion
    10.2.2. Analysis by Type of Expansion
    10.2.3. Analysis by Year and Type of Expansion
    10.2.4. Analysis by Company Size and Location of Headquarters
    10.2.5. Analysis by Location of Expanded Facility
    10.2.6. Active Players: Analysis by Number of Recent Expansions
    10.2.7. Analysis by Geography
    11. SURVEY ANALYSIS
    11.1. Chapter Overview
    11.2. Lyophilization Services Market for Biopharmaceuticals: List of Participating Companies
    11.2.1. Analysis by Seniority Level of Respondents
    11.2.2 Analysis by Type of Biologic Lyophilized
    11.2.3. Analysis by Type of Primary Packaging System
    11.2.4. Analysis by Scale of Operation
    11.2.5. Analysis by Additional Services Offered
    11.2.6. Analysis by Location of Lyophilization Facility
    11.2.7. Analysis by Share of Lyophilization Operations Outsourced
    11.2.8. Analysis by Likely Market Size
    11.2.9. Analysis of Likely Market Share by Type of Biologic Lyophilized
    11.2.10. Analysis of Likely Market Share by Geography
    12. CASE STUDY I: LYOPHILIZATION CYCLE DEVELOPMENT AND OPTIMIZATION
    12.1. Chapter Overview
    12.2. Lyophilization Cycle Development
    12.3. Lyophilization Cycle Optimization
    12.4. Lyophilization Cycle Development and Optimization: List of Service Providers
    12.4.1. Analysis by Company Size
    12.4.2. Analysis by Location of Headquarters
    12.4.3. Analysis by Type of Service Offered
    12.4.4 Lyophilization Cycle Development and Optimization Service Providers: Company Snapshots
    13. CASE STUDY II: ALTERNATIVE APPROACHES TO LYOPHILIZATION
    13.1. Chapter Overview
    13.2. Alternative Approaches to Lyophilization
    13.2.1. Spray Drying
    13.2.1.1. Spray Drying Process
    13.2.1.2. Applications of Spray Drying
    13.2.1.3. Spray Drying of Biopharmaceuticals
    13.2.1.4. Spray Drying Service Providers for Biopharmaceuticals
    13.2.1.5. Comparison of Lyophilization and Spray Drying
    13.2.2. Spray Freeze Drying
    13.2.3. Atmospheric Spray Freeze Drying
    13.2.4. Vacuum Foam Drying
    14. MARKET FORECAST AND OPPORTUNITY ANALYSIS
    14.1. Chapter Overview
    14.2. Forecast Methodology and Key Assumptions
    14.3. Global Lyophilization Services Market for Biopharmaceuticals, 2022-2035
    14.4. Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized, 2022 and 2035
    14.4.1. Lyophilization Services Market for Antibodies, 2022-2035
    14.4.2. Lyophilization Services Market for Cell and Gene Therapies, 2022-2035
    14.4.3. Lyophilization Services Market for Vaccines, 2022-2035
    14.4.4. Lyophilization Services Market for Other Biologics, 2022-2035
    14.5. Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Primary Packaging System, 2022 and 2035
    14.5.1. Lyophilization Services Market for Biopharmaceuticals for Vials, 2022-2035
    14.5.2. Lyophilization Services Market for Biopharmaceuticals for Syringes, 2022-2035
    14.5.3. Lyophilization Services Market for Biopharmaceuticals for Cartridges, 2022-2035
    14.5.4. Lyophilization Services Market for Biopharmaceuticals for Ampoules, 2022-2035
    14.5.5. Lyophilization Services Market for Biopharmaceuticals for Other Primary Packaging Systems, 2022-2035
    14.6. Lyophilization Services Market for Biopharmaceuticals: Distribution by Geography, 2022 and 2035
    14.6.1. Lyophilization Services Market for Biopharmaceuticals in North America, 2022-2035
    14.6.2. Lyophilization Services Market for Biopharmaceuticals in Europe, 2022-2035
    14.6.3. Lyophilization Services Market for Biopharmaceuticals in Asia Pacific, 2022-2035
    14.6.4. Lyophilization Services Market for Biopharmaceuticals in Middle East and North Africa, 2022-2035
    14.6.5. Lyophilization Services Market for Biopharmaceuticals in Latin America, 2022-2035
    14.6.6. Lyophilization Services Market for Biopharmaceuticals in Rest of the World, 2022-2035
    15. CONCLUDING REMARKS
    16. EXECUTIVE INSIGHTS
    16.1. Chapter Overview
    16.2. Pharmaceutical International
    16.2.1. Company Snapshot
    16.2.2. Interview Transcript: Brian Sasaki, Director of Business Development and Thomas Ingallinera, Vice President of Technical Support
    16.3. Curia
    16.3.1. Company Snapshot
    16.3.2. Interview Transcript: Doreen Coull, Regional Sales Director
    16.4. Emergent BioSolutions
    16.4.1. Company Snapshot
    16.4.2. Interview Transcript: Patrick DePalma, Former Director, CMO Business Development, BioDefense Division
    16.5. Liof Pharma
    16.5.1. Company Snapshot
    16.5.2. Interview Transcript: Rocio Gonzalez Rodriguez, Head of CDMO Project Management
    16.6. Vibalogics
    16.6.1. Company Snapshot
    16.6.2. Interview Transcript: John Shaw, Former Head of Business Development and Marketing
    16.7. Samsung Biologics
    16.7.1. Company Snapshot
    16.7.2. Interview Transcript: Sophia Kim, Commercial DP (Depository Participant) Sales / Group Leader
    16.8. Bioserv
    16.8.1. Company Snapshot
    16.8.2. Interview Transcript: Marianna Tcherpakov, Business Development Manager
    16.9. Symbiosis Pharmaceutical Services
    16.9.1. Company Snapshot
    16.9.2. Interview Transcript: Adam Inche, Marketing Manager
    16.10. Patheon
    16.10.1. Company Snapshot
    16.10.2. Interview Transcript: Adam Viverette, Manager of Lyophilization Operations
    16.11. Baxter BioPharma Solutions
    16.11.1. Company Snapshot
    16.11.2. Interview Transcript: Steven Nail, Principal Scientist
    17. APPENDIX 1: TABULATED DATA
    18. APPENDIX 2:
    LIST OF COMPANIES AND ORGANIZATIONS
    LIST OF FIGURES
    Figure 2.1 Executive Summary: Overall Market Landscape
    Figure 2.2 Executive Summary: Partnerships and Collaborations
    Figure 2.3 Executive Summary: Recent Expansions
    Figure 2.4 Executive Summary: Survey Analysis
    Figure 2.5 Executive Summary: Market Forecast
    Figure 3.1 Historical Evolution of Lyophilization
    Figure 3.2 Phase Diagram of Water
    Figure 3.3 Sublimation of Ice Crystals
    Figure 3.4 Key Steps Involved in Formulation and Filling of Biopharmaceuticals
    Figure 3.5 Key Components of Lyophilizer
    Figure 4.1 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Year of Establishment
    Figure 4.2 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Company Size
    Figure 4.3 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Location of Headquarters
    Figure 4.4 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Scale of Operation
    Figure 4.5 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Regulatory Certification / Accreditation
    Figure 4.6 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized
    Figure 4.7 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Process of Lyophilization
    Figure 4.8 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Primary Packaging System
    Figure 4.9 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Additional Services Offered
    Figure 5.1 Benchmark Analysis: Distribution by Company Size
    Figure 5.2 Benchmark Analysis: North America (Peer Group I)
    Figure 5.3 Benchmark Analysis: North America (Peer Group II)
    Figure 5.4 Benchmark Analysis: North America (Peer Group III)
    Figure 5.5 Benchmark Analysis: Europe (Peer Group IV)
    Figure 5.6 Benchmark Analysis: Europe (Peer Group V)
    Figure 5.7 Benchmark Analysis: Europe (Peer Group VI)
    Figure 5.8 Benchmark Analysis: Asia Pacific and Rest of the World (Peer Group VII)
    Figure 5.9 Benchmark Analysis: Asia Pacific and Rest of the World (Peer Group VIII)
    Figure 9.1 Partnerships and Collaborations: Cumulative Year-wise Trend, 2018-2021
    Figure 9.2 Partnerships and Collaborations: Distribution by Type of Partnership
    Figure 9.3 Partnerships and Collaborations: Distribution by Year and Type of Partnership
    Figure 9.4 Most Active Players: Distribution by Number of Partnerships
    Figure 9.5 Partnerships and Collaborations: Intercontinental and Intracontinental Deals
    Figure 9.6 Partnerships and Collaborations: International and Local Deals
    Figure 10.1 Recent Expansions: Cumulative Year-wise Trend, 2018-2021
    Figure 10.2 Recent Expansions: Distribution by Type of Expansion
    Figure 10.3 Recent Expansions: Distribution by Year and Type of Expansion
    Figure 10.4 Recent Expansions: Distribution by Company Size and Location of Headquarters
    Figure 10.5 Recent Expansions: Distribution by Location of Expanded Facility
    Figure 10.6 Recent Expansions: Distribution by Location of Expanded Facility and Type of Expansion
    Figure 10.7 Active Players: Distribution by Number of Recent Expansions
    Figure 10.8 Recent Expansions: Distribution by Geography
    Figure 11.1 Survey Analysis: Distribution by Geographical Location of Respondents
    Figure 11.2 Survey Analysis: Distribution by Seniority Levels of Respondents
    Figure 11.3 Survey Analysis: Distribution by Type of Biologic Lyophilized
    Figure 11.4 Survey Analysis: Distribution by Type of Primary Packaging System
    Figure 11.5 Survey Analysis: Distribution by Scale of Operation
    Figure 11.6 Survey Analysis: Distribution by Additional Services Offered
    Figure 11.7 Survey Analysis: Distribution by Location of Lyophilization Facility
    Figure 11.8 Survey Analysis: Distribution by Share of Lyophilization Operations Outsourced
    Figure 11.9 Survey Analysis: Distribution by Likely Current Market Size
    Figure 11.10 Survey Analysis: Distribution of Likely Market Share by Type of Biologic Lyophilized
    Figure 11.11 Survey Analysis: Distribution of Likely Market Share by Geography
    Figure 12.1 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Company Size
    Figure 12.2 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Location of Headquarters
    Figure 12.3 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Type of Service Offered
    Figure 13.1 Key Steps Involved in Spray Drying Process
    Figure 14.1 Global Lyophilization Services Market for Biopharmaceuticals, 2022-2035 (USD Billion)
    Figure 14.2 Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized, 2022 and 2035 (USD Billion)
    Figure 14.3 Lyophilization Services Market for Antibodies, 2022-2035 (USD Billion)
    Figure 14.4 Lyophilization Services Market for Cell and Gene Therapies, 2022-2035 (USD Billion)
    Figure 14.5 Lyophilization Services Market for Vaccines, 2022-2035 (USD Billion)
    Figure 14.6 Lyophilization Services Market for Other Biologics, 2022-2035 (USD Billion)
    Figure 14.7 Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Primary Packaging System, 2022 and 2035 (USD Billion)
    Figure 14.8 Lyophilization Services Market for Biopharmaceuticals Stored in Vials, 2022-2035 (USD Billion)
    Figure 14.9 Lyophilization Services Market for Biopharmaceuticals Stored in Syringes, 2022- 2035 (USD Billion)
    Figure 14.10 Lyophilization Services Market for Biopharmaceuticals Stored in Cartridges, 2022-2035 (USD Billion)
    Figure 14.11 Lyophilization Services Market for Biopharmaceuticals Stored in Ampoules, 2022-2035 (USD Billion)
    Figure 14.12 Lyophilization Services Market for Biopharmaceuticals Stored in Other Primary Packaging Systems, 2022-2035 (USD Billion)
    Figure 14.13 Lyophilization Services Market for Biopharmaceuticals: Distribution by Geography, 2022 and 2035 (USD Billion)
    Figure 14.14 Lyophilization Services Market for Biopharmaceuticals in North America, 2022- 2035 (USD Billion)
    Figure 14.15 Lyophilization Services Market for Biopharmaceuticals in Europe, 2022- 2035 (USD Billion)
    Figure 14.16 Lyophilization Services Market for Biopharmaceuticals in Asia Pacific, 2022- 2035 (USD Billion)
    Figure 14.17 Lyophilization Services Market for Biopharmaceuticals in Middle East and North Africa, 2022- 2035 (USD Billion)
    Figure 14.18 Lyophilization Services Market for Biopharmaceuticals in Latin America, 2022- 2035 (USD Billion)
    Figure 14.19 Lyophilization Services Market for Biopharmaceuticals in Rest of the World, 2022- 2035 (USD Billion)
    Figure 15.1 Concluding Remarks: Overall Market Landscape
    Figure 15.2 Concluding Remarks: Benchmark Analysis
    Figure 15.3 Concluding Remarks: Partnership and Collaborations
    Figure 15.4 Concluding Remarks: Recent Expansions
    Figure 15.5 Concluding Remarks: Market Forecast
    LIST OF TABLES
    Table 4.1 List of Lyophilization Service Providers for Biopharmaceuticals
    Table 5.1 Benchmark Analysis: Information on Peer Groups
    Table 6.1 Leading Lyophilization Service Providers for Biopharmaceuticals in North America
    Table 6.2 Baxter BioPharma Solutions: Company Snapshot
    Table 6.3 Baxter BioPharma Solutions: Lyophilization Service Offerings for Biopharmaceuticals
    Table 6.4 Baxter BioPharma Solutions: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 6.5 Baxter BioPharma Solutions: Recent Developments and Future Outlook
    Table 6.6 Curia: Company Snapshot
    Table 6.7 Curia: Lyophilization Service Offerings for Biopharmaceuticals
    Table 6.8 Curia: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 6.9 Curia: Recent Developments and Future Outlook
    Table 6.10 Emergent BioSolutions: Company Snapshot
    Table 6.11 Emergent BioSolutions: Lyophilization Service Offerings for Biopharmaceuticals
    Table 6.12 Emergent BioSolutions: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 6.13 Emergent BioSolutions: Recent Developments and Future Outlook
    Table 6.14 LSNE Contract Manufacturing: Company Snapshot
    Table 6.15 LSNE Contract Manufacturing: Lyophilization Service Offerings for Biopharmaceuticals
    Table 6.16 LSNE Contract Manufacturing: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 6.17 LSNE Contract Manufacturing: Recent Developments and Future Outlook
    Table 6.18 Lyophilization Technology: Company Snapshot
    Table 6.19 Lyophilization Technology: Lyophilization Service Offerings for Biopharmaceuticals
    Table 6.20 Lyophilization Technology: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 6.21 Lyophilization Technology: Recent Developments and Future Outlook
    Table 7.1 Leading Lyophilization Service Providers for Biopharmaceuticals in Europe
    Table 7.2 CordenPharma: Company Snapshot
    Table 7.3 CordenPharma: Lyophilization Service Offerings for Biopharmaceuticals
    Table 7.4 CordenPharma: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 7.5 CordenPharma: Recent Developments and Future Outlook
    Table 7.6 Coriolis Pharma: Company Snapshot
    Table 7.7 Coriolis Pharma: Lyophilization Service Offerings for Biopharmaceuticals
    Table 7.8 Coriolis Pharma: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 7.9 Coriolis Pharma: Recent Developments and Future Outlook
    Table 7.10 Northway Biotech: Company Snapshot
    Table 7.11 Northway Biotech: Lyophilization Service Offerings for Biopharmaceuticals
    Table 7.12 Northway Biotech: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 7.13 Northway Biotech: Recent Developments and Future Outlook
    Table 7.14 ProJect Pharmaceutics: Company Snapshot
    Table 7.15 ProJect Pharmaceutics: Lyophilization Service Offerings for Biopharmaceuticals
    Table 7.16 ProJect Pharmaceutics: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 7.17 Vetter Pharma: Company Snapshot
    Table 7.18 Vetter Pharma: Lyophilization Service Offerings for Biopharmaceuticals
    Table 7.19 Vetter Pharma: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 7.20 Vetter Pharma: Recent Developments and Future Outlook
    Table 8.1 Leading Lyophilization Service Providers for Biopharmaceuticals in Asia Pacific
    Table 8.2 BioZed Engineering: Company Snapshot
    Table 8.3 BioZed Engineering: Lyophilization Service Offerings for Biopharmaceuticals
    Table 8.4 BioZed Engineering: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 8.5 BioZed Engineering: Recent Developments and Future Outlook
    Table 8.6 CinnaGen: Company Snapshot
    Table 8.7 CinnaGen: Lyophilization Service Offerings for Biopharmaceuticals
    Table 8.8 CinnaGen: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 8.9 CinnaGen: Recent Developments and Future Outlook
    Table 8.9 MabPlex: Company Snapshot
    Table 8.10 MabPlex: Lyophilization Service Offerings for Biopharmaceuticals
    Table 8.11 MabPlex: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 8.12 MabPlex: Recent Developments and Future Outlook
    Table 8.13 Samsung Biologics: Company Snapshot
    Table 8.14 Samsung Biologics: Lyophilization Service Offerings for Biopharmaceuticals
    Table 8.15 Samsung Biologics: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 8.16 Samsung Biologics: Recent Developments and Future Outlook
    Table 8.17 WuXi Biologics: Company Snapshot
    Table 8.18 WuXi Biologics: Lyophilization Service Offerings for Biopharmaceuticals
    Table 8.19 WuXi Biologics: Information on Dedicated Biopharmaceutical Lyophilization Facilities
    Table 8.20 WuXi Biologics: Recent Developments and Future Outlook
    Table 9.1 Lyophilization Services for Biopharmaceuticals: List of Partnerships and Collaborations, 2018-2021
    Table 10.1 Lyophilization Services for Biopharmaceuticals: List of Recent Expansions, 2018-2021
    Table 11.1 Lyophilization Services Market for Biopharmaceuticals: List of Respondents
    Table 12.1 Lyophilization Cycle Development and Optimization: List of Service Providers
    Table 12.2 BSP Pharmaceuticals: Company Snapshot
    Table 12.3 CuriRx: Company Snapshot
    Table 12.4 GILYOS: Company Snapshot
    Table 12.5 Pierre Fabre: Company Snapshot
    Table 12.6 Singota Solutions: Company Snapshot
    Table 13.1 Spray Drying for Biopharmaceuticals: List of Service Providers
    Table 13.2 Comparison of Lyophilization and Spray Drying Process
    Table 16.1 Pharmaceutical International: Company Snapshot
    Table 16.2 Curia: Company Snapshot
    Table 16.3 Emergent BioSolutions: Company Snapshot
    Table 16.4 Liof Pharma: Company Snapshot
    Table 16.5 Vibalogics: Company Snapshot
    Table 16.6 Samsung Biologics: Company Snapshot
    Table 16.7 Bioserv: Company Snapshot
    Table 16.8 Symbiosis Pharmaceutical Services: Company Snapshot
    Table 16.9 Patheon: Company Snapshot
    Table 16.10 Baxter BioPharma Solutions: Company Snapshot
    Table 17.1 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Year of Establishment
    Table 17.2 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Company Size
    Table 17.3 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Location of Headquarters
    Table 17.4 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Scale of Operation
    Table 17.5 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Regulatory Certification / Accreditation
    Table 17.6 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized
    Table 17.7 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Process of Lyophilization
    Table 17.8 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Primary Packaging System
    Table 17.9 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Additional Services Offered
    Table 17.10 Benchmark Analysis: Asia Pacific and Rest of the World, Peer Group VII
    Table 17.11 Benchmark Analysis: Asia Pacific and Rest of the World, Peer Group VIII
    Table 17.12 Partnerships and Collaborations: Cumulative Year-wise Trend, 2018-2021
    Table 17.13 Partnerships and Collaborations: Distribution by Type of Partnership
    Table 17.14 Partnerships and Collaborations: Distribution by Year and Type of Partnership
    Table 17.15 Most Active Players: Distribution by Number of Partnerships
    Table 17.16 Partnerships and Collaborations: Intercontinental and Intracontinental Deals
    Table 17.17 Partnerships and Collaborations: International and Local Deals
    Table 17.18 Recent Expansions: Cumulative Year-wise Trend, 2018-2021
    Table 17.19 Recent Expansions: Distribution by Type of Expansion
    Table 17.20 Recent Expansions: Distribution by Year and Type of Expansion
    Table 17.21 Recent Expansions: Distribution by Company Size and Location of Headquarters
    Table 17.22 Recent Expansions: Distribution by Location of Expanded Facility
    Table 17.23 Recent Expansions: Distribution by Location of Expanded Facility and Type of Expansion
    Table 17.24 Active Players: Distribution by Number of Recent Expansions
    Table 17.25 Recent Expansions: Distribution by Geography
    Table 17.26 Survey Analysis: Distribution by Geographical Location of Respondents
    Table 17.27 Survey Analysis: Distribution by Seniority Levels of Respondents
    Table 17.28 Survey Analysis: Distribution by Type of Biologic Lyophilized
    Table 17.29 Survey Analysis: Distribution by Type of Primary Packaging System
    Table 17.30 Survey Analysis: Distribution by Scale of Operation
    Table 17.31 Survey Analysis: Distribution by Additional Services Offered
    Table 17.32 Survey Analysis: Distribution by Location of Lyophilization Facility
    Table 17.33 Survey Analysis: Distribution by Share of Lyophilization Operations Outsourced
    Table 17.34 Survey Analysis: Distribution by Likely Current Market Size
    Table 17.35 Survey Analysis: Distribution of Likely Market Share by Type of Biologic Lyophilized
    Table 17.36 Survey Analysis: Distribution Likely Market Share by Geography
    Table 17.37 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Company Size
    Table 17.38 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Location of Headquarters
    Table 17.39 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Type of Service Offered
    Table 17.40 Global Lyophilization Services Market for Biopharmaceuticals, 2022-2035 (USD Billion)
    Table 17.41 Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Biologic Lyophilized, 2022 and 2035 (USD Billion)
    Table 17.42 Lyophilization Services Market for Antibodies, 2022-2035 (USD Billion)
    Table 17.43 Lyophilization Services Market for Cell and Gene Therapies, 2022-2035 (USD Billion)
    Table 17.44 Lyophilization Services Market for Vaccines, 2022-2035 (USD Billion)
    Table 17.45 Lyophilization Services Market for Other Biologics, 2022-2035 (USD Billion)
    Table 17.46 Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Primary Packaging System, 2022 and 2035 (USD Billion)
    Table 17.47 Lyophilization Services Market for Biopharmaceuticals Stored in Vials, 2022-2035 (USD Billion)
    Table 17.48 Lyophilization Services Market for Biopharmaceuticals Stored in Syringes, 2022- 2035 (USD Billion)
    Table 17.49 Lyophilization Services Market for Biopharmaceuticals Stored in Cartridges, 2022- 2035 (USD Billion)
    Table 17.50 Lyophilization Services Market for Biopharmaceuticals Stored in Ampoules, 2022- 2035 (USD Billion)
    Table 17.51 Lyophilization Services Market for Biopharmaceuticals Stored in Other Primary Packaging Systems, 2022- 2035 (USD Billion)
    Table 17.52 Lyophilization Services Market for Biopharmaceuticals: Distribution by Geography, 2022 and 2035 (USD Billion)
    Table 17.53 Lyophilization Services Market for Biopharmaceuticals in North America, 2022- 2035 (USD Billion)
    Table 17.54 Lyophilization Services Market for Biopharmaceuticals in Europe, 2022- 2035 (USD Billion)
    Table 17.55 Lyophilization Services Market for Biopharmaceuticals in Asia Pacific, 2022- 2035 (USD Billion)
    Table 17.56 Lyophilization Services Market for Biopharmaceuticals in Middle East and North Africa, 2022- 2035 (USD Billion)
    Table 17.57 Lyophilization Services Market for Biopharmaceuticals in Latin America, 2022- 2035 (USD Billion)
    Table 17.58 Lyophilization Services Market for Biopharmaceuticals in Rest of the World, 2022- 2035 (USD Billion)
    LIST OF COMPANIES AND ORGANIZATIONS
    The following companies and organizations have been mentioned in the report.
    1. AbbVie
    2. Affinity Biologicals (Acquired by Precision BioLogic)
    3. Affinity Life Sciences
    4. Air Products
    5. Ajinomoto Bio-Pharma Services
    6. Alcami
    7. APTSol
    8. Arbor Investments
    9. Argonaut Manufacturing Services
    10. Attwill Medical Solutions
    11. Axcellerate Pharma (Acquired by Generic Specialties)
    12. Baccinex
    13. Basic Pharma
    14. Baxter BioPharma Solutions
    15. Berkshire Sterile Manufacturing
    16. BioConnection
    17. Biofortuna
    18. BIOLYPH
    19. Biopharma Group
    20. BioReliance
    21. Bioserv
    22. BioTechLogic
    23. BioTechnique
    24. BioZed Engineering
    25. Boehringer Ingelheim
    26. Bovogen Biologicals
    27. Bryllan
    28. BSP Pharmaceuticals
    29. Burrard Pharmaceuticals
    30. Canada Peptide
    31. CARBOGEN AMCIS (Acquired by Dishman Pharmaceuticals and Chemicals)
    32. Catalent
    33. Cenexi
    34. CinnaGen
    35. CoolVacuum (Acquired by Dara Pharma)
    36. CordenPharma
    37. Coriolis Pharma
    38. Curia
    39. CuriRx
    40. Dalton Pharma Services (Acquired by Seikagaku)
    41. Dara Pharmaceutical Equipment
    42. DavosPharma
    43. Emergent BioSolutions
    44. EnWave
    45. Eurofins
    46. Eurogentec
    47. Eurolyo (A Subsidiary of Groupe)
    48. European Medical Contract Manufacturing (EMCM)
    49. FAMAR
    50. Flow Sciences
    51. Fluorogenics (Acquired by New England Biolabs)
    52. Fresenius Kabi
    53. GEA
    54. GeneMe
    55. GILYOS
    56. Gipharma (Acquired by Advanced Accelerator Applications)
    57. GlaxoSmithKline (GSK)
    58. Goodwin Biotechnology
    59. GP Pharm
    60. Grand River Aseptic Manufacturing (GRAM)
    61. Groupe Berkem
    62. HALIX
    63. HTD Biosystems
    64. Hycult Biotech
    65. IBEX Pharmaceuticals
    66. IDT Biologika
    67. Integrated DNA Technologies (IDT)
    68. Integrity Bio (Acquired by Curia)
    69. IRISYS (Acquired by Societal CDMO)
    70. Jubilant HollisterStier
    71. KABS Pharmaceutical Services
    72. Kemp Proteins
    73. Kemwell Biopharma
    74. Lab-i-DOSiTECNO Pharma Technologies
    75. Labyrinth BioPharma (Formerly known as AB BioTechnologies)
    76. LakePharma (Acquired by Curia)
    77. Liof Pharma
    78. Lonza
    79. LSNE Contract Manufacturing (Acquired by PCI Pharma Services)
    80. Luina Bio
    81. LYOCONTRACT
    82. LyoGen (Acquired by Argonaut Manufacturing Services)
    83. LyoHUB
    84. Lyophilization Technology (LTI)
    85. MabPlex
    86. MBU-Technology
    87. Medicago
    88. Miltenyi Biotec
    89. Mycenax Biotech
    90. nanoTools Antibody Technology
    91. National Collection of Industrial, Food and Marine Bacteria (NCIMB)
    92. Nektar Therapeutics
    93. New England Biolabs (NEB)
    94. Nitto Avecia Pharma Services
    95. Northway Biotech
    96. Oncotec Pharma Produktion
    97. OPTIMA pharma
    98. Oregon Freeze Dry (Acquired by Arbor Investments)
    99. Parker Freeze Dry
    100. Patheon (Acquired by Thermo Fischer Scientific)
    101. PaxVax
    102. PCI Pharma Services
    103. Pfizer CentreOne
    104. Pharma Gen
    105. Pharmaceutics International
    106. Pierre Fabre
    107. Piramal Pharma Solutions
    108. Precision BioLogic
    109. Premas Biotech
    110. Profacgen
    111. ProForm Fabrication
    112. ProJect Pharmaceutics
    113. PSC Biotech
    114. PYRAMID Laboratories
    115. Quality BioResources
    116. Recipharm
    117. Rentschler Fill Solutions
    118. Resilience
    119. SafeBridge Consultants
    120. Samsung Biologics
    121. Seikagaku
    122. Sentinel Diagnostics
    123. Singota Solutions
    124. SP Scientific
    125. Sublime Stericeuticals
    126. Symbiosis Pharmaceutical Services
    127. SynCo Bio Partners
    128. SYNERLAB Group
    129. Therapure Biopharma (Acquired by Resilience)
    130. TriPharm Services (Acquired by Alcami)
    131. Vetter Pharma
    132. Vibalogics
    133. VxP Pharma
    134. Wacker Biotech
    135. WuXi Biologics

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