Active Pharmaceutical Ingredients (APIs) Market, Global Forecast 2023-2027, Industry Trends, Growth, Impact of Inflation, Opportunity Company Analysis
Global Active Pharmaceutical Ingredients (APIs) market was at US$ 190.5 Billion in 2022, and it will expand at a CAGR of 6.52 from 2022 to 2027. The API (active pharmaceutical ingredient) is the part of any medication that produces the intended health effects. The APIs are made from raw materials with a specified strength and chemical concentration. Some drugs, such as combination therapies, have multiple APIs that may act differently or treat different symptoms.
Active Pharmaceutical Ingredients (API) of good quality is core to manufacturing effective and safe essential drugs. The price of APIs is the main cost driver for manufacturing. Unfortunately, only a few large manufacturers of finished pharmaceutical products have their API manufacturing capabilities, and none can make all required APIs in-house. The API market provides a challenge, particularly to small manufacturers, who have limited means to verify the quality of the APIs they buy. One possible way to address this problem would be to broaden the WHO Prequalification system to include APIs for drugs on the WHO Model List for Essential Medicines.
Trends in Ageing Population
The global geriatric population is rising. According to the WHO, by 2030, every 1 out of 6 people worldwide will be 60 years or over. The population share of aged 60 years & above will increase to 1.4 billion from 1 billion in 2020. The global population aged 60 years and older will double by 2050. In addition, the number of people 80 years or older is anticipated to triple between 2020 and 2050 and reach 426 million. Aging weakens the immune system and increases a patient's susceptibility to acquiring infectious diseases. Moreover, impairment in body functions enhances the chances of getting other conditions, such as CVD and diabetes.
Type of Molecule and Synthetic Insights
Active ingredients are the substances in drugs responsible for the beneficial health effects experienced by consumers. Based on Molecule, APIs are categorized into Small and Large. In addition, synthetic types have been classified into synthetic and biotech. Synthetic APIs, known as small molecules, constitute a large share of the pharmaceutical market, with many small-molecule drugs commercially available. On the other hand, Biotech APIs are used in biologics, which are increasingly becoming the top-selling drugs in the market. However, despite the growing demand, biologics are currently significantly fewer in number compared to small molecule drugs.
Type Insights: Generic APIs will lead the global market
On the basis of type, the API market is categorized into generic and innovative APIs. Generic APIs will lead the global market because of promising government guidelines, recognized R&D facilities, and augmented subsidies for creative drug development. In addition, due to widespread research in this field, numerous novel, ground-breaking products are in the pipeline and are estimated to be introduced in future years. According to our research findings Worldwide Active pharmaceutical ingredients (APIs) market will surpass US$ 261.3 Billion by 2027.
Type of Manufacturers Insights
Among different types of manufacturers involved in the API market, Captive API occupied most of the revenue shares because of the stress-free obtainability of raw materials and thorough capitalization of foremost companies for the progress of high-end manufacturing facilities. Merchant API is projected to be the fastest-growing sector in the years to come. The segment development is compelled by influences like the high cost of in-house engineering of these molecules and the increasing demand for biopharmaceuticals.
Application Insights: Cardiology Dominates the Market Share
APIs find widespread application in Cardiology, Oncology, CNS & Neurology, Orthopaedics, Endocrinology, and Others. Cardiology occupied the majority share of the market due to escalating commonness of target diseases internationally. For example, as per the WHO, cardiovascular diseases may result in about 17.9 million deaths annually, where heart attacks and strokes instigate 85% of these deaths.
Regional Insights: North America Dominates the API Market Globally
API Market has been categorized geographically into North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America dominates in the global market and expected to increase its market in the future, owing to the rising aging population and the increasing incidences of disease. Driven by lower costs, API manufacturing has slowly shifted from the historical leaders in Western countries to newer firms in India and China.
In addition, several regulatory authorities are involved to ensure that firms manufacture APIs and final formulations in a quality manner. The geographic location of the manufacturer and market, as well as the financing source, determines which regulatory agencies are involved. For example, APIs intended for final formulations in sub-Saharan Africa are often less regulated due to weaker national regulatory agencies and cost-sensitive markets.
Key Companies & Market Share Insights
Generally speaking, the API market is very competitive with many producers. As a result, API manufacturers specialize and target their manufacturing based on market opportunities and firm skills. The presence of prominent players in this market space significantly diminishes the prospects for a new entry into the market, as it is challenging to match the high capital requirements. Some prominent players in the global active pharmaceutical ingredients market are Sanofi SA, F. Hoffmann-LA Roche Ltd, Pfizer, Abbott, Bayer AG, Merck & Co. Inc, Boehringer Ingelheim Gmbh, GlaxoSmithKline Plc, Novartis AG, Eli Lilly Company, and Teva Pharmaceutical.
For instance, in August 2021, Teva Pharmaceutical and MED in Cell received approval from the U.S FDA for a new drug application to treat schizophrenia.
In December 2021, Novasep invested around EUR 6 million in France to upgrade its capabilities to newer APIs in areas such as oncology, central nervous system (CNS), and infectious diseases.
Renub Research latest Report ”Global Active Pharmaceutical Ingredients Market by Molecule type (Small and Large), Type (Innovative and Generic), Manufacture (Captive and Merchant),Application (Cardiology, Oncology, CNS &Neurology, Orthopedic, Endocrinology & Others), Synthetic (Biotech and Synthetic), Region (North America, Europe, Asia – Pacific, Latin America & Middle East & Africa) Company (Sanofi SA, F. Hoffmann-LA Roche Ltd, Pfizer, Abbortt, Bayer AG, Merck & Co. Inc, Boehringer Ingelheim Gmbh, Glaxosmithkline Plc, Novartis AG, Eli Lilly Company, and Teva Pharmaceutical)” provides complete details on provides complete details on Global Active Pharmaceutical Ingredients Industry.
Molecule – Active Pharmaceutical Ingredients (APIs) Market
1. Small Molecule
2. Large Molecule
Type – Active Pharmaceutical Ingredients (APIs) Market
1. Innovative APIs
2. Generic APIs
Manufacturers – Active Pharmaceutical Ingredients (APIs) Market
1. Captive Manufacturers
2. Merchant Manufacturers
Application – Active Pharmaceutical Ingredients (APIs) Market
1. Cardiology
2. Oncology
3. CNS & Neurology
4. Orthopaedic
5. Endocrinology
6. Others
Synthetic – Active Pharmaceutical Ingredients (APIs) Market
1. Biotech
2. Synthetic
Region – Active Pharmaceutical Ingredients (APIs) Market
1. North America
2. Europe
3. Asia Pacific
4. Latin America
5. Middle East & Africa
Company
1. Sanofi SA
2. F. Hoffmann-LA Roche Ltd
3. Pfizer
4. Abbortt
5. Bayer AG
6. Merck & Co. Inc
7. Boehringer Ingelheim Gmbh
8. GlaxoSmithKline Plc
9. Novartis AG
10. Eli Lilly Company
11. Teva Pharmaceutical
- 1. Introduction
- 2. Research & Methodology
- 3. Executive Summary
- 4. Market Dynamics
- 4.1 Growth Drivers
- 4.2 Challenges
- 5. Global Active Pharmaceutical Ingredients Market
- 6. Market Share – Active Pharmaceutical Ingredients Market
- 6.1 By Molecule
- 6.2 By Type
- 6.3 By Synthetic
- 6.4 By Manufacturer Type
- 6.5 By Application
- 6.6 By Region
- 7. Molecule – Active Pharmaceutical Ingredients Market
- 7.1 Small Molecule
- 7.2 Large Molecule
- 8. Type - Active Pharmaceutical Ingredients Market
- 8.1 Innovative
- 8.2 Gereric
- 9. Synthetic - Active Pharmaceutical Ingredients Market
- 9.1 Biotech
- 9.2 Synthetic
- 10. Manufacturer - Active Pharmaceutical Ingredients Market
- 10.1 Captive
- 10.2 Merchant
- 11. Application - Active Pharmaceutical Ingredients Market
- 11.1 Cardiology
- 11.2 Oncology
- 11.3 CNS& Neurology
- 11.4 Orthopedic
- 11.5 Endocrinology
- 11.6 Others
- 12. Region – Active Pharmaceutical Ingredients Market
- 12.1 North America
- 12.2 Europe
- 12.3 Asia Pacific
- 12.4 Latin America
- 12.5 Middle East & Africa
- 13. Key Players Analysis
- 13.1 Sanofi SA
- 13.1.1 Overview
- 13.1.2 Initiative / Strategy
- 13.1.3 Net Sales
- 13.2 F. Hoffmann-La Roche Ltd
- 13.2.1 Overview
- 13.2.2 Initiative / Strategy
- 13.2.3 Net Sales
- 13.3 Pfizer Inc
- 13.3.1 Overview
- 13.3.2 Initiative / Strategy
- 13.3.3 Net Sales
- 13.4 Abbott
- 13.4.1 Overview
- 13.4.2 Initiative / Strategy
- 13.4.3 Net Sales
- 13.5 Bayer AG
- 13.5.1 Overview
- 13.5.2 Initiative / Strategy
- 13.5.3 Net Sales
- 13.6 Merck & Co.Inc
- 13.6.1 Overview
- 13.6.2 Initiative / Strategy
- 13.6.3 Net Sales
- 13.7 Boehringer Ingelheim GmbH
- 13.7.1 Overview
- 13.7.2 Initiative / Strategy
- 13.7.3 Net Sales
- 13.8 Glaxosmithkline Plc
- 13.8.1 Overview
- 13.8.2 Initiative / Strategy
- 13.8.3 Net Sales
- 13.9 Novartis AG
- 13.9.1 Overview
- 13.9.2 Initiative / Strategy
- 13.9.3 Net Sales
- 13.10 Eli Lilly and Company
- 13.10.1 Overview
- 13.10.2 Initiative / Strategy
- 13.10.3 Net Sales
- 13.11 Teva Pharmaceutical Industries Ltd
- 13.11.1 Overview
- 13.11.2 Initiative / Strategy
- 13.11.3 Net Sales
- List of Figures:
- Figure-01: Global – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-02: Global – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-03: Molecule – Small Molecule Market (Billion US$), 2017 – 2022
- Figure-04: Molecule – Forecast for Small Molecule Market (Billion US$), 2023 – 2027
- Figure-05: Molecule – Large Molecule Market (Billion US$), 2017 – 2022
- Figure-06: Molecule – Forecast for Large Molecule Market (Billion US$), 2023 – 2027
- Figure-07: Type – Innovative Market (Billion US$), 2017 – 2022
- Figure-08: Type – Forecast for Innovative Market (Billion US$), 2023 – 2027
- Figure-09: Type – Gereric Market (Billion US$), 2017 – 2022
- Figure-10: Type – Forecast for Gereric Market (Billion US$), 2023 – 2027
- Figure-11: Synthetic – Biotech Market (Billion US$), 2017 – 2022
- Figure-12: Synthetic – Forecast for Biotech Market (Billion US$), 2023 – 2027
- Figure-13: Synthetic – Synthetic Market (Billion US$), 2017 – 2022
- Figure-14: Synthetic – Forecast for Synthetic Market (Billion US$), 2023 – 2027
- Figure-15: Manufacturer – Captive Market (Billion US$), 2017 – 2022
- Figure-16: Manufacturer – Forecast for Captive Market (Billion US$), 2023 – 2027
- Figure-17: Manufacturer – Merchant Market (Billion US$), 2017 – 2022
- Figure-18: Manufacturer – Forecast for Merchant Market (Billion US$), 2023 – 2027
- Figure-19: Application – Cardiology Market (Billion US$), 2017 – 2022
- Figure-20: Application – Forecast for Cardiology Market (Billion US$), 2023 – 2027
- Figure-21: Application – Oncology Market (Billion US$), 2017 – 2022
- Figure-22: Application – Forecast for Oncology Market (Billion US$), 2023 – 2027
- Figure-23: Application – CNS& Neurology Market (Billion US$), 2017 – 2022
- Figure-24: Application – Forecast for CNS& Neurology Market (Billion US$), 2023 – 2027
- Figure-25: Application – Orthopedic Market (Billion US$), 2017 – 2022
- Figure-26: Application – Forecast for Orthopedic Market (Billion US$), 2023 – 2027
- Figure-27: Application – Endocrinology Market (Billion US$), 2017 – 2022
- Figure-28: Application – Forecast for Endocrinology Market (Billion US$), 2023 – 2027
- Figure-29: Application – Others Market (Billion US$), 2017 – 2022
- Figure-30: Application – Forecast for Others Market (Billion US$), 2023 – 2027
- Figure-31: North America – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-32: North America – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-33: Europe – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-34: Europe – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-35: Asia Pacific – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-36: Asia Pacific – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-37: Latin America – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-38: Latin America – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-39: Middle East &Africa – Active Pharmaceutical Ingredients Market (Billion US$), 2017 – 2022
- Figure-40: Middle East &Africa – Forecast for Active Pharmaceutical Ingredients Market (Billion US$), 2023 – 2027
- Figure-41: Sanofi SA – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-42: Sanofi SA – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-43: F. Hoffmann-La Roche Ltd – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-44: F. Hoffmann-La Roche Ltd – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-45: Pfizer Inc – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-46: Pfizer Inc – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-47: Abbott – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-48: Abbott – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-49: Bayer AG – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-50: Bayer AG – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-51: Merck & Co.Inc – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-52: Merck & Co.Inc – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-53: Boehringer Ingelheim GmbH – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-54: Boehringer Ingelheim GmbH – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-55: Glaxosmithkline Plc – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-56: Glaxosmithkline Plc – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-57: Novartis AG – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-58: Novartis AG – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-59: Eli Lilly and Company – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-60: Eli Lilly and Company – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- Figure-61: Teva Pharmaceutical Industries Ltd – Global Revenue Market (Billion US$), 2017 – 2022
- Figure-62: Teva Pharmaceutical Industries Ltd – Forecast for Global Revenue Market (Billion US$), 2023 – 2027
- List of Tables:
- Table-01: Global – Active Pharmaceutical Ingredients Market Share by Molecule (Percent), 2017 – 2022
- Table-02: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Molecule (Percent), 2023 – 2027
- Table-03: Global – Active Pharmaceutical Ingredients Market Share by Type (Percent), 2017 – 2022
- Table-04: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Type (Percent), 2023 – 2027
- Table-05: Global – Active Pharmaceutical Ingredients Market Share by Synthetic (Percent), 2017 – 2022
- Table-06: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Synthetic (Percent), 2023 – 2027
- Table-07: Global – Active Pharmaceutical Ingredients Market Share by Manufacturer Type (Percent), 2017 – 2022
- Table-08: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Manufacturer Type (Percent), 2023 – 2027
- Table-09: Global – Active Pharmaceutical Ingredients Market Share by Application (Percent), 2017 – 2022
- Table-10: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Application (Percent), 2023 – 2027
- Table-11: Global – Active Pharmaceutical Ingredients Market Share by Regions (Percent), 2017 – 2022
- Table-12: Global – Forecast for Active Pharmaceutical Ingredients Market Share by Regions (Percent), 2023 – 2027
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