A SGLT2 Inhibitors Market Size, Share, Trends, Industry Analysis Report: By Indication (Cardiovascular, Chronic Kidney Disease (CKD), Type 2 Diabetes, and Others), Drug, Distribution Channel, and Region (North America, Europe

SGLT2 Inhibitors Market Size, Share, Trends, Industry Analysis Report: By Indication (Cardiovascular, Chronic Kidney Disease (CKD), Type 2 Diabetes, and Others), Drug, Distribution Channel, and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) – Market Forecast, 2025 – 2034

The global SGLT2 inhibitors market size is expected to reach USD 32.75 billion by 2034, according to a new study by Polaris Market Research. The report “SGLT2 Inhibitors Market Size, Share, Trends, Industry Analysis Report, By Indication (Cardiovascular, Chronic Kidney Disease (CKD), Type 2 Diabetes, and Others), Drug, Distribution Channel, and Region; Segment Forecast, 2025-2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

The sodium-glucose cotransporter 2 (SGLT2) inhibitors market has emerged as a significant segment of the global pharmaceutical industry, driven by the increasing prevalence of type 2 diabetes (T2D), heart failure, and chronic kidney diseases (CKD). SGLT2 inhibitors are a class of drugs that work by blocking the sodium-glucose cotransporter 2, a protein responsible for reabsorbing glucose from the kidneys into the bloodstream

The market for SGLT2 inhibitors is experiencing significant growth due to their increasing efficacy in treating type 2 diabetes (T2D) by inhibiting glucose reabsorption in the kidneys and thereby lowering blood sugar levels. This expansion is attributed to the increasing rising obesity rates, sedentary lifestyles, aging populations, and unhealthy diets. Genetic predisposition, urbanization, and economic differences also contribute to the surge in diabetes cases in North America and globally. Thereby boosting demand for SGLT2 inhibitors.

The COVID-19 pandemic has further accelerated the adoption of SGLT2 inhibitors as diabetic patients sought effective treatments to manage their condition and mitigate the risk of severe COVID-19 complications. Additionally, the pandemic has led to a surge in the use of online pharmacies, facilitating accessibility to these medications. Furthermore, favorable reimbursement policies, regulatory approvals, and ongoing innovations in drug formulations further bolster the market.

SGLT2 Inhibitors Market Report Highlights

In 2024, the type 2 diabetes segment accounted for the largest revenue share in the SGLT2 inhibitors market. Urbanization often leads to lifestyle changes characterized by decreased physical activity, increased consumption of processed foods, and higher stress levels. These factors contribute to the rising prevalence of obesity and type 2 diabetes, significantly driving the SGLT2 inhibitors market.

The online pharmacies segment is growing at the highest CAGR during the forecast period. Online pharmacies often offer competitive pricing and discounts on medications as a result of reduced overhead costs associated with online operations.

In 2024, North America SGLT2 inhibitors market accounted for the largest market due to the increasing chronic stress and poor mental. Additionally, the increasing prevalence of diabetes patients in North America has led to a higher demand for SGLT2 inhibitors in the region.

Asia Pacific accounted for the fastest growth in the market. Governments in the region are increasingly investing in healthcare infrastructure and initiatives to enhance access and quality. These efforts support pharmaceutical markets and the adoption of medications like SGLT2 inhibitors.

The global key market players include AstraZeneca; Boehringer Ingelheim International GmbH; Bristol-Myers Squibb Company; Eli Lilly and Company; Glenmark Pharmaceuticals Ltd.; Johnson & Johnson Services, Inc. (Janssen Pharmaceuticals, Inc.); Lexicon Pharmaceuticals, Inc.; Merck & Co., Inc.; Sanofi; and TheracosBio, LLC.

Polaris Market Research has segmented the SGLT2 inhibitors market report based on indication, drug, distribution channel, and region:

By Indication Outlook (Revenue - USD Billion, 2020 - 2034)

Cardiovascular

Chronic Kidney Disease (CKD)

Type 2 Diabetes

Others

By Drug Outlook (Revenue - USD Billion, 2020 - 2034)

Farxiga (Dapagliflozin)

Inpefa (Sotagliflozin)

Invokana (Canagliflozin)

Jardiance (Empagliflozin)

Qtern (Dapagliflozin/Saxagliptin)

Other SGLT2 Inhibitors

By Distribution Channel Outlook (Revenue - USD Billion, 2020 - 2034)

Hospital Pharmacies

Online Pharmacies

Retail Pharmacies

By Regional Outlook (Revenue - USD Billion, 2020 - 2034)

North America

• US
• Canada
• Europe
• Germany
• UK
• France
• Italy
• Spain
• Russia
• Netherlands
• Rest of Europe
• Asia Pacific
• China
• India
• Japan
• South Korea
• Vietnam
• Indonesia
• Malaysia
• Australia
• Rest of Asia Pacific
• Latin America
• Argentina
• Brazil
• Mexico
• Rest of Latin America
• Middle East & Africa
• UAE
• Saudi Arabia
• Israel
• South Africa
• Rest of Middle East & Africa