Oligonucleotide Synthesis Market Share, Size, Trends, Industry Analysis Report, By Product (Synthesized Oligonucleotide Products, Equipment, Reagents, Equipment, and Services); By Application; By Region; Segment Forecast, 2024- 2032

Oligonucleotide Synthesis Market Share, Size, Trends, Industry Analysis Report, By Product (Synthesized Oligonucleotide Products, Equipment, Reagents, Equipment, and Services); By Application; By Region; Segment Forecast, 2024- 2032



The global oligonucleotide synthesis market size is expected to reach USD 10.17 billion by 2032, according to a new study by Polaris Market Research. The report “Oligonucleotide Synthesis Market Share, Size, Trends, Industry Analysis Report, By Product (Synthesized Oligonucleotide Products, Equipment, Reagents, Equipment, and Services); By Application; By Region; Segment Forecast, 2024- 2032” gives a detailed insight into current market dynamics and provides analysis on future market growth.

Oligonucleotide therapeutics exhibit substantial promise in addressing chronic conditions such as retinal disorders, cancers, and cardiovascular, among others. The continuous evolution and newfound implementation of oligo sequences across various biotechnological domains are anticipated to propel market expansion. A significant upsurge in demand for molecular diagnostics, especially in precision care, stands out as a crucial emerging application for oligonucleotide synthesis.

The integration of advanced methodologies such as high-throughput sequencing and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) for gene expression analysis has streamlined genome modification and genetic screening, thereby influencing the demand for oligonucleotide synthesis. Manufacturers are actively investing in technology development to facilitate the production of longer oligonucleotides with enhanced precision and higher yield, aligning with the increasing demand for customized oligos.

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The pivotal driver behind oligonucleotide synthesis market growth lies in the presence of a regulatory framework supportive of genomic advancements. Anticipated changes in regulatory policies aimed at creating a well-defined environment for advanced biological research and its application in human use are poised to exert a substantial impact on the demand for oligonucleotide synthesis. Healthcare sectors, particularly in stem cells, regenerative medicine, genetic engineering, and synthetic biology, are identified as key areas with significant potential. An illustrative example is the International Society for Stem Cell Research (ISSCR) ethics and public policy committee, which endeavors to address concerns through transparent discussions. This committee, comprising global experts in ethics, law, and social policy, plays a vital role in recognizing and resolving pertinent issues.

Moreover, the market undergoes rigorous regulatory scrutiny, particularly in the clinical applications of genomics, where stringent monitoring and restrictions prevail in many countries. Some jurisdictions permit genetic research in non-human use sectors. Anticipated shifts in regulatory policies geared towards establishing a well-defined framework for advanced biological research and its application in human use are poised to exert a substantial impact on the demand for oligonucleotide synthesis. These changes reflect the dynamic landscape of regulatory considerations, affecting the market's trajectory and emphasizing the need for compliance and adaptability in the evolving field of genomics.

Oligonucleotide Synthesis Market Report Highlights

- In 2023, the synthesized oligonucleotide products segment is expected to witness highest growth during forecast period owing to increased prevalence of genomic studies

- PCR primers segment is expected to dominate the oligonucleotide synthesis market during forecast period. This is attributed to increase in detecting and measuring gene expression

- In 2023, North America accounted for the largest revenue share due to presence of major players, technological advancements, and growing awareness of genetic disorders.

- The market is highly competitive owing to the existence of market players with a global presence, including ATDBio Ltd., Bio-Synthesis Inc., Biosearch Technologies, Eurofins Genomics, GE Healthcare, among others.

Polaris Market Research has segmented the oligonucleotide synthesis market report based on product, application, and region:

Oligonucleotide Synthesis, Product Outlook (Revenue - USD Billion, 2019 - 2032)

- Synthesized Oligonucleotide Products

- Equipment

- Reagents

- Services

Oligonucleotide Synthesis, Application Outlook (Revenue - USD Billion, 2019 - 2032)

- PCR Assays and Panels

- PCR Primers

- DNA Microarrays

- Sequencing

- Antisense Oligonucleotides

- Fluorescence In Situ Hybridization (FISH)

- Others

Oligonucleotide Synthesis, Regional Outlook (Revenue - USD Billion, 2019 - 2032)

- North America

- U.S.

- Canada

- Europe

- France

- Germany

- UK

- Italy

- Netherlands

- Spain

- Russia

- Rest of Europe

- Asia Pacific

- Japan

- China

- India

- Malaysia

- Indonesia

- South Korea

- Australia

- Rest of APAC

- Latin America

- Brazil

- Mexico

- Argentina

- Rest of LA

- Middle East & Africa

- Saudi Arabia

- UAE

- Israel

- South Africa

- Rest of MEA


1. Introduction
1.1. Report Description
1.1.1. Objectives of the Study
1.1.2. Market Scope
1.1.3. Assumptions
1.2. Stakeholders
2. Executive Summary
2.1. Market Highlights
3. Research Methodology
3.1. Overview
3.1.1. Data Mining
3.2. Data Sources
3.2.1. Primary Sources
3.2.2. Secondary Sources
4. Global Oligonucleotide Synthesis Market Insights
4.1. Oligonucleotide Synthesis Market – Industry Snapshot
4.2. Oligonucleotide Synthesis Market Dynamics
4.2.1. Drivers and Opportunities
4.2.1.1. Increasing utilization of synthesized oligonucleotides in molecular diagnostics and clinical applications
4.2.1.2. Increased investment in pharmaceutical and biotechnology companies
4.2.2. Restraints and Challenges
4.2.2.1. Erosion of costs
4.3. Porter’s Five Forces Analysis
4.3.1. Bargaining Power of Suppliers (Moderate)
4.3.2. Threats of New Entrants: (Low)
4.3.3. Bargaining Power of Buyers (Moderate)
4.3.4. Threat of Substitute (Moderate)
4.3.5. Rivalry among existing firms (High)
4.4. PESTLE Analysis
4.5. Oligonucleotide Synthesis Industry trends
4.6. Value Chain Analysis
4.7. COVID-19 Impact Analysis
5. Global Oligonucleotide Synthesis Market, by Product
5.1. Key Findings
5.2. Introduction
5.2.1. Global Oligonucleotide Synthesis, by Product, 2019-2032 (USD Billion)
5.3. Synthesized Oligonucleotide Products
5.3.1. Global Oligonucleotide Synthesis Market, by Synthesized Oligonucleotide Products, by Region, 2019-2032 (USD Billion)
5.4. Equipment
5.4.1. Global Oligonucleotide Synthesis Market, by Equipment, by Region, 2019-2032 (USD Billion)
5.5. Reagents
5.5.1. Global Oligonucleotide Synthesis Market, by Reagents, by Region, 2019-2032 (USD Billion)
5.6. Services
5.6.1. Global Oligonucleotide Synthesis Market, by Services, by Region, 2019-2032 (USD Billion)
6. Global Oligonucleotide Synthesis Market, by Application
6.1. Key Findings
6.2. Introduction
6.2.1. Global Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
6.3. PCR Assays and Panels
6.3.1. Global Oligonucleotide Synthesis Market, by PCR Assays and Panels, by Region, 2019-2032 (USD Billion)
6.4. PCR Primers
6.4.1. Global Oligonucleotide Synthesis Market, by PCR Primers, by Region, 2019-2032 (USD Billion)
6.5. DNA Microarrays
6.5.1. Global Oligonucleotide Synthesis Market, by DNA Microarrays, by Region, 2019-2032 (USD Billion)
6.6. Sequencing
6.6.1. Global Oligonucleotide Synthesis Market, by Sequencing, by Region, 2019-2032 (USD Billion)
6.7. Antisense Oligonucleotides
6.7.1. Global Oligonucleotide Synthesis Market, by Antisense Oligonucleotides, by Region, 2019-2032 (USD Billion)
6.8. Fluorescence In Situ Hybridization (FISH)
6.8.1. Global Oligonucleotide Synthesis Market, by Fluorescence In Situ Hybridization (FISH), by Region, 2019-2032 (USD Billion)
6.9. Others
6.9.1. Global Oligonucleotide Synthesis Market, by Others, by Region, 2019-2032 (USD Billion)
7. Global Oligonucleotide Synthesis Market, by Geography
7.1. Key findings
7.2. Introduction
7.2.1. Oligonucleotide Synthesis Market Assessment, By Geography, 2019-2032 (USD Billion)
7.3. Oligonucleotide Synthesis Market – North America
7.3.1. North America: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.3.2. North America: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.3.3. Oligonucleotide Synthesis Market – U.S.
7.3.3.1. U.S.: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.3.3.2. U.S.: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.3.4. Oligonucleotide Synthesis Market – Canada
7.3.4.1. Canada: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.3.4.2. Canada: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4. Oligonucleotide Synthesis Market – Europe
7.4.1. Europe: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.2. Europe: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.3. Oligonucleotide Synthesis Market – UK
7.4.3.1. UK: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.3.2. UK: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.4. Oligonucleotide Synthesis Market – France
7.4.4.1. France: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.4.2. France: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.5. Oligonucleotide Synthesis Market – Germany
7.4.5.1. Germany: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.5.2. Germany: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.6. Oligonucleotide Synthesis Market – Italy
7.4.6.1. Italy: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.6.2. Italy: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.7. Oligonucleotide Synthesis Market – Spain
7.4.7.1. Spain: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.7.2. Spain: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.8. Oligonucleotide Synthesis Market – Netherlands
7.4.8.1. Netherlands: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.8.2. Netherlands: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.4.9. Oligonucleotide Synthesis Market – Russia
7.4.9.1. Russia: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.4.9.2. Russia: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5. Oligonucleotide Synthesis Market – Asia Pacific
7.5.1. Asia Pacific: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.2. Asia Pacific: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.3. Oligonucleotide Synthesis Market – China
7.5.3.1. China: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.3.2. China: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.4. Oligonucleotide Synthesis Market – India
7.5.4.1. India: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.4.2. India: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.5. Oligonucleotide Synthesis Market – Malaysia
7.5.5.1. Malaysia: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.5.2. Malaysia: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.6. Oligonucleotide Synthesis Market – Japan
7.5.6.1. Japan: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.6.2. Japan: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.7. Oligonucleotide Synthesis Market – Indonesia
7.5.7.1. Indonesia: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.7.2. Indonesia: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.5.8. Oligonucleotide Synthesis Market – South Korea
7.5.8.1. South Korea: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.5.8.2. South Korea: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.6. Oligonucleotide Synthesis Market – Middle East & Africa
7.6.1. Middle East & Africa: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.6.2. Middle East & Africa: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.6.3. Oligonucleotide Synthesis Market – Saudi Arabia
7.6.3.1. Saudi Arabia: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.6.3.2. Saudi Arabia: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.6.4. Oligonucleotide Synthesis Market – UAE
7.6.4.1. UAE: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.6.4.2. UAE: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.6.5. Oligonucleotide Synthesis Market – Israel
7.6.5.1. Israel: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.6.5.2. Israel: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.6.6. Oligonucleotide Synthesis Market – South Africa
7.6.6.1. South Africa: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.6.6.2. South Africa: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.7. Oligonucleotide Synthesis Market – Latin America
7.7.1. Latin America: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.7.2. Latin America: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.7.3. Oligonucleotide Synthesis Market – Mexico
7.7.3.1. Mexico: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.7.3.2. Mexico: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.7.4. Oligonucleotide Synthesis Market – Brazil
7.7.4.1. Brazil: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.7.4.2. Brazil: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
7.7.5. Oligonucleotide Synthesis Market – Argentina
7.7.5.1. Argentina: Oligonucleotide Synthesis Market, by Application, 2019-2032 (USD Billion)
7.7.5.2. Argentina: Oligonucleotide Synthesis Market, by Product, 2019-2032 (USD Billion)
8. Competitive Landscape
8.1. Expansion and Acquisition Analysis
8.1.1. Expansion
8.1.2. Acquisitions
8.2. Partnerships/Collaborations/Agreements/Exhibitions
9. Company Profiles
9.1. Agilent Technologies
9.1.1. Company Overview
9.1.2. Financial Performance
9.1.3. Product Benchmarking
9.1.4. Recent Development
9.2. ATDBio Ltd
9.2.1. Company Overview
9.2.2. Financial Performance
9.2.3. Product Benchmarking
9.2.4. Recent Development
9.3. Bio-Synthesis Inc.
9.3.1. Company Overview
9.3.2. Financial Performance
9.3.3. Product Benchmarking
9.3.4. Recent Development
9.4. Biosearch Technologies
9.4.1. Company Overview
9.4.2. Financial Performance
9.4.3. Product Benchmarking
9.4.4. Recent Development
9.5. Eurofins Genomics
9.5.1. Company Overview
9.5.2. Financial Performance
9.5.3. Product Benchmarking
9.5.4. Recent Development
9.6. GE Healthcare
9.6.1. Company Overview
9.6.2. Financial Performance
9.6.3. Product Benchmarking
9.6.4. Recent Development
9.7. Genewiz
9.7.1. Company Overview
9.7.2. Financial Performance
9.7.3. Product Benchmarking
9.7.4. Recent Development
9.8. GenScript Corporation
9.8.1. Company Overview
9.8.2. Financial Performance
9.8.3. Product Benchmarking
9.8.4. Recent Development
9.9. Integrated DNA Technologies (IDT)
9.9.1. Company Overview
9.9.2. Financial Performance
9.9.3. Product Benchmarking
9.9.4. Recent Development
9.10. LGC Biosearch Technologies
9.10.1. Company Overview
9.10.2. Financial Performance
9.10.3. Product Benchmarking
9.10.4. Recent Development
9.11. Merck KGaA (including Sigma-Aldrich)
9.11.1. Company Overview
9.11.2. Financial Performance
9.11.3. Product Benchmarking
9.11.4. Recent Development
9.12. Nitto Denko Avecia Inc.
9.12.1. Company Overview
9.12.2. Financial Performance
9.12.3. Product Benchmarking
9.12.4. Recent Development
9.13. Thermo Fisher Scientific
9.13.1. Company Overview
9.13.2. Financial Performance
9.13.3. Product Benchmarking
9.13.4. Recent Development
9.14. TriLink BioTechnologies
9.14.1. Company Overview
9.14.2. Financial Performance
9.14.3. Product Benchmarking
9.14.4. Recent Development
9.15. Twist Bioscience
9.15.1. Company Overview
9.15.2. Financial Performance
9.15.3. Product Benchmarking
9.15.4. Recent Development

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