Methylmalonic Acidemia Market Share, Size, Trends, Industry Analysis Report, By Disorder (Homocystinuria, Isolated Methylmalonic Acidurias, Combined Methylmalonic Aciduria); By Indication; By Distribution Channel; By Region; Segment Forecast, 2023 - 2032

Methylmalonic Acidemia Market Share, Size, Trends, Industry Analysis Report, By Disorder (Homocystinuria, Isolated Methylmalonic Acidurias, Combined Methylmalonic Aciduria); By Indication; By Distribution Channel; By Region; Segment Forecast, 2023 - 2032

The global methylmalonic acidemia market size is expected treach USD 14.78 billion by 2032, according ta new study by Polaris Market Research. The report “Methylmalonic Acidemia Share, Size, Trends, Industry Analysis Report, By Disorder Type (Homocystinuria, Isolated Methylmalonic Acidurias, Combined Methylmalonic Aciduria); By Indication; By Distribution Channel; By Region; Segment Forecast, 2023 - 2032” gives a detailed insight intcurrent market dynamics and provides analysis on future market growth.

Growing consumer awareness of the benefits of methylmalonic acid supplements is expected tdrive market growth. A growing number of research studies on the role of methylmalonic acid in various diseases is expected tdrive demand for this compound in the coming years. HomoShear Therapeutics blazoned in March 2021 that the oral small patch HST5040 can be used ttreat methylmalonic acidemia and propionic acidemia. The IDOL study, a phase 2 trial of HST5040 for the treatment of MMA and PA in cases progressed 2 and over, has begun.

In December 2021, Omega Quant presented the Vitamin B12 Test, containing a sample collection kit that allows for at-home testing. Methylmalonic acidemia is a rare and potentially fatal inheritable complaint that affects about one in every 50,000 newborns. A mutation in the methyl malonyl-CoA mutase gene prevents the body from duly recycling certain fats and proteins in the most common form of MMA.

The first case was cured on June 2021, according tthe company. The trail is anticipated tinclude seven leading centers in the United States and in Saudi Arabia, The Sunrise trail I originally enrolled 3-12 times old cases with the eventuality tinclude babies as youthful as 6 months old after meeting certain safety parameters and biomarkers discovery testimate LB-001 at an early age before unrecoverable damage has passed.

Recurrent infections can be caused by neutropenia during the non-acidotic phase of organic acidemia. It may be unrelated tbone marrow suppression, which is produced by decreased synthesis of these cells as a result of lower pH in the acidotic phase of the illness. More research is needed tdetermine the influence of pH and the acidic environment on neutrophils, as well as the root cause of neutropenia in patients with organic acidemia.

Methylmalonic Acidemia Market Report Highlights

Isolated Methylmalonic Acidurias segment is anticipated tgrow at a rapid rate as the pathogenic mutations in the gene for methyl malonyl-CoA mutase or in the genes for enzymes involved in the intracellular metabolism of cobalamin can induce isolated methylmalonic aciduria.

Hyperglycemia accounted for a major global revenue share which is accelerated due trising disease awareness and increased healthcare spending around the world, the market will grow in size, allowing drug manufacturers texpand their market penetration.

Hospitals accounted for the largest profit share. The market for hospitals is anticipated tgrow significantly over the coming many times as a result of expanding public-private partnerships.

North America has supremacy in the market due tcontinuous lifestyle changes, increased healthcare expenditure, and increased availability of funds for research.

The global players include Biosint, Cayman Chemical, Ceva Sante Animale, Chengda Pharmaceuticals, DSM, John Lee Pharmaceuticals, Merck, Sanofi, TokyChemical Industry, and Lonza group.

Polaris Market Research has segmented the methylmalonic acidemia market report based on Disorder Type, Indication, Distribution Channel, and region:

Methylmalonic Acidemia, Disorder Type Outlook (Revenue - USD Billion, 2019 - 2032)

Homocystinuria

Isolated Methylmalonic Acidurias

Combined methylmalonic Aciduria

Methylmalonic Acidemia, Indication Outlook (Revenue - USD Billion, 2019 - 2032)

Acidosis

Ketosis

Hyperammonemia

Hypoglycemia

Hyperglycemia

Neutropenia

Other Indications

Methylmalonic Acidemia, Distribution Channel Outlook (Revenue - USD Billion, 2019 - 2032)

Hospitals

Pharmacies

Clinics

Others

Methylmalonic Acidemia, Regional Outlook (Revenue - USD Billion, 2019 - 2032)

North America

U.S.

Canada

Europe

Germany

UK

France

Italy

Spain

Russia

Netherlands

Asia Pacific

China

India

Japan

South Korea

Indonesia

Malaysia

Latin America

Argentina

Brazil

Mexico

Middle East & Africa

UAE

Saudi Arabia

Israel

South Africa


1. Introduction
1.1. Report Description
1.1.1. Objectives of the Study
1.1.2. Market Scope
1.1.3. Assumptions
1.2. Stakeholders
2. Executive Summary
2.1. Market Highlights
3. Research Methodology
3.1. Overview
3.1.1. Data Mining
3.2. Data Sources
3.2.1. Primary Sources
3.2.2. Secondary Sources
4. Global Methylmalonic Acidemia Market Insights
4.1. Methylmalonic Acidemia Market – Distribution Channel Snapshot
4.2. Methylmalonic Acidemia Market Dynamics
4.2.1. Drivers and Opportunities
4.2.1.1. Increase in understanding and awareness of methylmalonic acidemia
4.2.1.2. Rising R&D initiatives to bring about medical modernization
4.2.2. Restraints and Challenges
4.2.2.1. High cost
4.3. Porter’s Five Forces Analysis
4.3.1. Bargaining Power of Suppliers (Moderate)
4.3.2. Threats of New Entrants: (Low)
4.3.3. Bargaining Power of Buyers (Moderate)
4.3.4. Threat of Substitute (Moderate)
4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. Methylmalonic Acidemia Market Distribution Channel Trends
4.6. Value Chain Analysis
4.7. COVID-19 Impact Analysis
5. Global Methylmalonic Acidemia Market, by Disorder Type
5.1. Key Findings
5.2. Introduction
5.2.1. Global Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
5.3. Homocystinuria
5.3.1. Global Methylmalonic Acidemia Market, by Homocystinuria, by Region, 2019-2032 (USD Billion)
5.4. Isolated Methylmalonic Acidurias
5.4.1. Global Methylmalonic Acidemia Market, by Isolated Methylmalonic Acidurias, by Region, 2019-2032 (USD Billion)
5.5. Combined methylmalonic Aciduria
5.5.1. Global Methylmalonic Acidemia Market, by Combined methylmalonic Aciduria, by Region, 2019-2032 (USD Billion)
6. Global Methylmalonic Acidemia Market, by Indication
6.1. Key Findings
6.2. Introduction
6.2.1. Global Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
6.3. Acidosis
6.3.1. Global Methylmalonic Acidemia Market, by Acidosis, by Region, 2019-2032 (USD Billion)
6.4. Ketosis
6.4.1. Global Methylmalonic Acidemia Market, by Ketosis, by Region, 2019-2032 (USD Billion)
6.5. Hyperammonemia
6.5.1. Global Methylmalonic Acidemia Market, by Hyperammonemia, by Region, 2019-2032 (USD Billion)
6.6. Hypoglycaemia
6.6.1. Global Methylmalonic Acidemia Market, by Hypoglycaemia, by Region, 2019-2032 (USD Billion)
6.7. Hyperglycaemia
6.7.1. Global Methylmalonic Acidemia Market, by Hyperglycaemia, by Region, 2019-2032 (USD Billion)
6.8. Neutropenia
6.8.1. Global Methylmalonic Acidemia Market, by Neutropenia, by Region, 2019-2032 (USD Billion)
6.9. Other Indications
6.9.1. Global Methylmalonic Acidemia Market, by Other Indications, by Region, 2019-2032 (USD Billion)
7. Global Methylmalonic Acidemia Market, by Distribution Channel
7.1. Key Findings
7.2. Introduction
7.2.1. Global Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
7.3. Hospitals
7.3.1. Global Methylmalonic Acidemia Market, by Hospitals, By Region, 2019-2032 (USD Billion)
7.4. Pharmacies
7.4.1. Global Methylmalonic Acidemia Market, by Pharmacies, By Region, 2019-2032 (USD Billion)
7.5. Clinics
7.5.1. Global Methylmalonic Acidemia Market, by Clinics, By Region, 2019-2032 (USD Billion)
7.6. Others
7.6.1. Global Methylmalonic Acidemia Market, by Others, By Region, 2019-2032 (USD Billion)
8. Global Methylmalonic Acidemia Market, by Geography
8.1. Key findings
8.2. Introduction
8.2.1. Methylmalonic Acidemia Market Assessment, By Geography, 2019-2032 (USD Billion)
8.3. Methylmalonic Acidemia Market – North America
8.3.1. North America: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.3.2. North America: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.3.3. North America: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.3.4. Methylmalonic Acidemia Market – U.S.
8.3.4.1. U.S.: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.3.4.2. U.S.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.3.4.3. U.S.: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.3.5. Methylmalonic Acidemia Market – Canada
8.3.5.1. Canada: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.3.5.2. Canada.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.3.5.3. Canada: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4. Methylmalonic Acidemia Market – Europe
8.4.1. Europe: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.2. Europe.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.3. Europe: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.4. Methylmalonic Acidemia Market – UK
8.4.4.1. UK: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.4.2. UK.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.4.3. UK: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.5. Methylmalonic Acidemia Market – France
8.4.5.1. France: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.5.2. France.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.5.3. France: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.6. Methylmalonic Acidemia Market – Germany
8.4.6.1. Germany: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.6.2. Germany.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.6.3. Germany: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.7. Methylmalonic Acidemia Market – Italy
8.4.7.1. Italy: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.7.2. Italy.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.7.3. Italy: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.8. Methylmalonic Acidemia Market – Spain
8.4.8.1. Spain: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.8.2. Spain.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.8.3. Spain: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.9. Methylmalonic Acidemia Market – Netherlands
8.4.9.1. Netherlands: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.9.2. Netherlands.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.9.3. Netherlands: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.4.10. Methylmalonic Acidemia Market – Russia
8.4.10.1. Russia: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.4.10.2. Russia.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.4.10.3. Russia: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5. Methylmalonic Acidemia Market – Asia Pacific
8.5.1. Asia Pacific: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.2. Asia Pacific.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.3. Asia Pacific: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.4. Methylmalonic Acidemia Market – China
8.5.4.1. China: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.4.2. China.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.4.3. China: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.5. Methylmalonic Acidemia Market – India
8.5.5.1. India: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.5.2. India.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.5.3. India: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.6. Methylmalonic Acidemia Market – Malaysia
8.5.6.1. Malaysia: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.6.2. Malaysia.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.6.3. Malaysia: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.7. Methylmalonic Acidemia Market – Japan
8.5.7.1. Japan: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.7.2. Japan.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.7.3. Japan: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.8. Methylmalonic Acidemia Market – Indonesia
8.5.8.1. Indonesia: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.8.2. Indonesia.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.8.3. Indonesia: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.5.9. Methylmalonic Acidemia Market – South Korea
8.5.9.1. South Korea: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.5.9.2. South Korea.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.5.9.3. South Korea: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.6. Methylmalonic Acidemia Market – Middle East & Africa
8.6.1. Middle East & Africa: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.6.2. Middle East & Africa.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.6.3. Middle East & Africa: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.6.4. Methylmalonic Acidemia Market – Saudi Arabia
8.6.4.1. Saudi Arabia: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.6.4.2. Saudi Arabia.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.6.4.3. Saudi Arabia: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.6.5. Methylmalonic Acidemia Market – UAE
8.6.5.1. UAE: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.6.5.2. UAE.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.6.5.3. UAE: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.6.6. Methylmalonic Acidemia Market – Israel
8.6.6.1. Israel: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.6.6.2. Israel.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.6.6.3. Israel: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.6.7. Methylmalonic Acidemia Market – South Africa
8.6.7.1. South Africa: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.6.7.2. South Africa.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.6.7.3. South Africa: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.7. Methylmalonic Acidemia Market – Latin America
8.7.1. Latin America: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.7.2. Latin America.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.7.3. Latin America: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.7.4. Methylmalonic Acidemia Market – Mexico
8.7.4.1. Mexico: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.7.4.2. Mexico.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.7.4.3. Mexico: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.7.5. Methylmalonic Acidemia Market – Brazil
8.7.5.1. Brazil: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.7.5.2. Brazil.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.7.5.3. Brazil: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
8.7.6. Methylmalonic Acidemia Market – Argentina
8.7.6.1. Argentina: Methylmalonic Acidemia Market, by Disorder Type, 2019-2032 (USD Billion)
8.7.6.2. Argentina.: Methylmalonic Acidemia Market, by Distribution Channel, 2019-2032 (USD Billion)
8.7.6.3. Argentina: Methylmalonic Acidemia Market, by Indication, 2019-2032 (USD Billion)
9. Competitive Landscape
9.1. Expansion and Acquisition Analysis
9.1.1. Expansion
9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions
10. Company Profiles
10.1. Biosint
10.1.1. Company Overview
10.1.2. Financial PerIndicationance
10.1.3. Indication Benchmarking
10.1.4. Recent Development
10.2. Cayman Chemical
10.2.1. Company Overview
10.2.2. Financial PerIndicationance
10.2.3. Indication Benchmarking
10.2.4. Recent Development
10.3. Ceva Sante Animale
10.3.1. Company Overview
10.3.2. Financial PerIndicationance
10.3.3. Indication Benchmarking
10.3.4. Recent Development
10.4. Chengda Pharmaceuticals
10.4.1. Company Overview
10.4.2. Financial PerIndicationance
10.4.3. Indication Benchmarking
10.4.4. Recent Development
10.5. John lee pharmaceuticals
10.5.1. Company Overview
10.5.2. Financial PerIndicationance
10.5.3. Indication Benchmarking
10.5.4. Recent Development
10.6. Merck
10.6.1. Company Overview
10.6.2. Financial PerIndicationance
10.6.3. Indication Benchmarking
10.6.4. Recent Development
10.7. Sanofi
10.7.1. Company Overview
10.7.2. Financial PerIndicationance
10.7.3. Indication Benchmarking
10.7.4. Recent Development
10.8. Tokyo Chemical Industry
10.8.1. Company Overview
10.8.2. Financial PerIndicationance
10.8.3. Indication Benchmarking
10.8.4. Recent Development
10.9. Lonza group
10.9.1. Company Overview
10.9.2. Financial PerIndicationance
10.9.3. Indication Benchmarking
10.9.4. Recent Development

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