Protein Purification & Isolation Market - Technology [Preparative Chromatography, (Affinity, Ion Exchange), Ultrafiltration], Product [Consumable (Kit, Reagent), Instrument], Application (Protein-Protein Interaction), End-user, Global Forecast 2023-2032

Protein Purification & Isolation Market - Technology [Preparative Chromatography, (Affinity, Ion Exchange), Ultrafiltration], Product [Consumable (Kit, Reagent), Instrument], Application (Protein-Protein Interaction), End-user, Global Forecast 2023-2032


Protein Purification and Isolation Market size is estimated to expand at 10.5% CAGR from 2023-2032 driven by the continual advancements in chromatography, electrophoresis, and filtration technologies. The improved capabilities of these technologies in terms of resolution, speed, and scalability is significantly enhancing the purification process for enabling researchers and biopharmaceutical companies to isolate high-quality proteins for various therapeutic and diagnostic applications.

The rising rate of manufacturing of protein drugs, including insulin and antibodies is leading to the higher need for purification of protein. The ongoing R&D efforts to help reduce the production costs will also support the market growth. For instance, in February 2023, MIT engineers devised a new way to perform purification by deploying specialized nanoparticles to rapidly crystallize proteins for making protein drugs more accessible and affordable in developing countries.

The protein purification & isolation industry is segmented into technology, product, application, end-user, and region.

With respect to technology, the market value from the ultrafiltration segment is likely to gain significant traction through 2032. The growth can be attributed to the growing adoption of this technology to selectively retain proteins while eliminating contaminants for streamlining the purification workflow and ensuring high yields of pure proteins. Additionally, the surging need for cost-effectiveness, scalability, and gentle operating conditions are contributing to the increasing preference for ultrafiltration technology in various biopharmaceutical and research applications.

In terms of application, the protein purification & isolation industry from the drug screening segment generated substantial revenue in 2022 and is projected to record robust growth through 2032. The increasing focus on drug discovery and development coupled with the rising demand for high-quality purified proteins for preclinical and clinical research is propelling the adoption of advanced purification and isolation techniques. The application of purified proteins in understanding disease mechanisms and developing personalized therapeutics will further accelerate the segment expansion.

Regionally, Europe protein purification & isolation market is set to exhibit robust growth from 2023 to 2032 attributed to the presence of robust biopharmaceutical and biotechnology sectors. Massive investments in R&D activities along with the growing emphasis on personalized medicine and targeted therapeutics are fueling the demand for advanced protein purification and isolation technologies. Moreover, the presence of well-established healthcare infrastructure and the strong focus on academic research and industrial collaborations will augment the regional industry outlook.


Chapter 1 Methodology & Scope
1.1 Market definition
1.2 Base estimates & calculations
1.3 Forecast calculation
1.4 Covid-19 impact analysis at global level
1.5 Data validation
1.6 Data sources
1.6.1 Secondary
1.6.1.1 Paid sources
1.6.1.2 Public sources
1.6.2 Primary
Chapter 2 Executive Summary
2.1 Protein purification & isolation industry 360 degree synopsis, 2018 – 2032 (USD Million)
2.1.1 Business trends
2.1.2 Region trends
2.1.3 Technology trends
2.1.4 Product trends
2.1.5 Application trends
2.1.6 End-user trends
Chapter 3 Protein Purification & Isolation Market Insights
3.1 Industry landscape, 2018 – 2032 (USD Million)
3.2 Industry impact forces
3.2.1 Growth drivers
3.2.1.1 Increasing research and development in pharmaceutical and biotechnology companies
3.2.1.2 Rising demand for biologics
3.2.1.3 Technological advancements in protein purification and isolation techniques
3.2.2 Industry pitfalls & challenges
3.2.2.1 High cost of purification instruments
3.2.2.2 Lack of skilled technicians
3.3 Growth potential analysis
3.3.1 By technology
3.3.2 By product
3.3.3 By application
3.3.4 By end-user
3.4 COVID-19 impact analysis
3.5 Regulatory landscape
3.6 Porter’s analysis
3.7 PESTEL analysis
Chapter 4 Competitive Landscape, 2022
4.1 Introduction
4.2 Company matrix analysis, 2022
4.3 Competitive positioning matrix, 2022
4.4 Strategic dashboard, 2022
Chapter 5 Protein Purification & Isolation Market Estimates and Forecast, By Technology (USD Million)
5.1 Key trends, by technology
5.2 Preparative chromatography
5.2.1 Ion exchange chromatography
5.2.1.1 Immobilized metal ion affinity chromatography (IMAC)
5.2.1.2 Immunoaffinity chromatography (IAC)
5.2.1.3 Bead-based chromatography
5.2.2 Affinity chromatography
5.2.3 Reverse-phase chromatography
5.2.4 Hydrophobic charge induction chromatography
5.2.5 Size exclusion chromatography
5.3 Ultrafiltration
5.4 Precipitation
5.5 Electrophoresis
5.5.1 Gel electrophoresis
5.5.2 Isoelectric focusing electrophoresis
5.5.3 Capillary electrophoresis
5.6 Western blotting
5.7 Dialysis & diafiltration
5.8 Centrifugation
Chapter 6 Protein Purification & Isolation Market Estimates and Forecast, By Product (USD Million)
6.1 Key trends, by product
6.2 Consumables
6.2.1 Protein purification kits
6.2.2 Reagents
6.2.3 Prepared columns
6.2.4 Protein purification resins
6.2.5 Magnetic beads
6.2.5.1 Tagged magnetic beads
6.2.5.2 Non-tagged magnetic beads
6.3 Other consumables
Chapter 7 Protein Purification & Isolation Market Estimates and Forecast, By Application (USD Million)
7.1 Key trends, by application
7.2 Protein-protein interaction studies
7.3 Drug screening
7.4 Biomarker discovery
7.5 Target identification
7.6 Disease diagnostics & monitoring
7.7 Protein therapeutics
Chapter 8 Protein Purification & Isolation Market Estimates and Forecast, By End-User (USD Million)
8.1 Key trends, by end-user
8.2 Academic medical institutes
8.3 Pharmaceutical & biotechnology companies
8.4 Hospitals & diagnostics centers
8.5 Contract research organizations
Chapter 9 Protein Purification & Isolation Market Estimates and Forecast, By Region (USD Million)
9.1 Key trends, by region
9.2 North America
9.2.1 U.S.
9.2.2 Canada
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 France
9.3.4 Spain
9.3.5 Italy
9.3.6 Switzerland
9.3.7 Rest of Europe
9.4 Asia Pacific
9.4.1 China
9.4.2 Japan
9.4.3 India
9.4.4 Australia
9.4.5 South Korea
9.4.6 Rest of Asia Pacific
9.5 Latin America
9.5.1 Brazil
9.5.2 Mexico
9.5.3 Rest of Latin America
9.6 Middle East & Africa
9.6.1 South Africa
9.6.2 Saudi Arabia
9.6.3 Rest of Middle East & Africa
Chapter 10 Company Profiles
10.1 Thermo Fisher Scientific Inc.
10.2 Merck & Co. Inc.
10.3 QIAGEN NV
10.4 Bio-Rad Laboratories, Inc.
10.5 Agilent Technologies, Inc.
10.6 Promega Corporation
10.7 Danaher Corporation
10.8 Norgen Biotek Corp.
10.9 Abcam plc
10.10 Purolite

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