Opioid Induced Constipation Drugs Market Size - By Drug Class (PAMORAs, Chloride channel-2 Activators, Laxatives, PPI, Anti-diarrheal), Prescription Type (Prescribed, OTC), Route of Administration - Global Forecast, 2024 - 2032

Opioid Induced Constipation Drugs Market Size - By Drug Class (PAMORAs, Chloride channel-2 Activators, Laxatives, PPI, Anti-diarrheal), Prescription Type (Prescribed, OTC), Route of Administration - Global Forecast, 2024 - 2032


Opioid induced constipation drugs market size is poised to witness 4.8% CAGR between 2024 and 2032. The increasing prevalence of chronic pain conditions requiring opioid therapy has led to the rise in opioid prescriptions. As healthcare providers are striving to address this significant side effect of opioid use, there is a growing demand for effective opioid induced constipation (OIC) drugs. Additionally, advancements in pharmaceutical research have resulted in the development of novel medications, such as peripherally acting mu-opioid receptor antagonists (PAMORAs) to offer improved efficacy and tolerability compared to traditional laxatives.

Strategic collaborations and partnerships between pharmaceutical companies and healthcare providers are also helping in driving innovations. For example, in January 2024, SteriPack, a pharmaceutical contract packaging company, revealed a strategic alliance with SHL Medical, a supplier of sophisticated drug delivery systems. Such partnerships are facilitating the development and commercialization of new therapeutic options by leveraging combined expertise and resources to address the unmet needs in OIC management. Moreover, the regulatory initiatives aimed at promoting safe prescribing practices and enhancing patient access to OIC drugs will contribute to the market growth.

The opioid induced constipation drugs market is segmented into drug class, prescription type, route of administration, distribution channel, and region.

Based on drug class, the market value from anti-diarrheal segment is anticipated to witness 4.3% CAGR through 2032, due to its complementary role in managing opioid-induced gastrointestinal symptoms. Patients prescribed with opioids often experience a delicate balance between constipation and diarrhea, with anti-diarrheal medications serving as a crucial adjunct therapy to alleviate symptoms of diarrhea.

In terms of route of administration, the OIC drugs industry from the injectable segment is predicted to record 4.5% gains up to 2032. This is owing to its efficacy and convenience in delivering rapid relief for severe constipation associated with opioid use. Injectable formulations offer a direct route of administration, bypassing gastrointestinal barriers and ensuring prompt onset of action, which is particularly beneficial for patients experiencing acute symptoms of opioid induced constipation.

Asia Pacific opioid induced constipation drugs market size will grow significantly at 5.6% CAGR through 2032, attributed to the rising adoption of opioid medications in clinical practices. The increasing prevalence of chronic pain conditions is pushing the need for opioid therapies across the region. The rapidly aging population and expanding healthcare infrastructure is driving the demand for effective management strategies. Furthermore, the growing awareness among healthcare providers and patients about the importance of addressing opioid-induced gastrointestinal side effects will fuel the regional product adoption.


Chapter 1 Methodology & Scope
1.1 Market scope & definition
1.2 Base estimates & calculations
1.3 Data collection
1.4 Forecast parameters
1.5 Data validation
1.6 Data sources
1.6.1 Primary
1.6.2 Secondary
1.6.2.1 Paid sources
1.6.2.2 Public sources
Chapter 2 Executive Summary
2.1 Industry 360 degree synopsis
Chapter 3 Industry Insights
3.1 Industry ecosystem analysis
3.2 Industry impact forces
3.2.1 Growth drivers
3.2.1.1 Increasing use of opioids
3.2.1.2 Rising prevalence of gastrointestinal disorders
3.2.1.3 Surging expenditure on the R&D of novel treatments
3.2.2 Industry pitfalls & challenges
3.2.2.1 Lack of awareness regarding adverse effects of opioids
3.3 Growth potential analysis
3.4 Porter's analysis
3.4.1 Supplier power
3.4.2 Buyer power
3.4.3 Threat of new entrants
3.4.4 Threat of substitutes
3.4.5 Industry rivalry
3.5 PESTEL analysis
3.6 Pricing analysis, 2023
3.7 Reimburesemnt scenario
3.8 Regulatory landscape
3.9 Technological landscape
Chapter 4 Competitive Landscape, 2023
4.1 Introduction
4.2 Company matrix analysis
4.3 Company market share analysis
4.4 Competitive positioning matrix
4.5 Strategy dashboard
Chapter 5 Market Estimates and Forecast, By Drug Class, 2018 - 2032 ($ Mn)
5.1 Key trends
5.2 Peripherally acting mu-opioid receptor agonists (PAMORAs)
5.3 Chloride channel-2 activators
5.4 Laxatives
5.5 Proton pump inhibitors
5.6 Anti-diarrheal
5.7 Other drug classes
Chapter 6 Market Estimates and Forecast, By Prescription Type, 2018 - 2032 ($ Mn)
6.1 Key trends
6.2 Prescribed drugs
6.3 Over-the-counter (OTC) drugs
Chapter 7 Market Estimates and Forecast, By Route of Administration, 2018 - 2032 ($ Mn)
7.1 Key trends
7.2 Oral
7.3 Injectable
Chapter 8 Market Estimates and Forecast, By By Distribution Channel, 2018 - 2032 ($ Mn)
8.1 Key trends
8.2 Hospital pharmacies
8.3 Retail pharmacies
8.4 Online pharmacies
Chapter 9 Market Estimates and Forecast, By Region, 2018 - 2032 ($ Mn)
9.1 Key trends
9.2 North America
9.2.1 U.S.
9.2.2 Canada
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 France
9.3.4 Italy
9.3.5 Spain
9.3.6 Rest of Europe
9.4 Asia Pacific
9.4.1 China
9.4.2 Japan
9.4.3 India
9.4.4 Australia
9.4.5 South Korea
9.4.6 Rest of Asia Pacific
9.5 Latin America
9.5.1 Brazil
9.5.2 Mexico
9.5.3 Argentina
9.5.4 Rest of Latin America
9.6 Middle East and Africa
9.6.1 Saudi Arabia
9.6.2 South Africa
9.6.3 UAE
9.6.4 Rest of Middle East and Africa
Chapter 10 Company Profiles
10.1 Atlantis Consumer Healthcare Inc.
10.2 Bausch Health Companies Inc.
10.3 Bayer AG
10.4 Cumberland Pharmaceuticals Inc.
10.5 Mallinckrodt Pharmaceuticals
10.6 Sanofi
10.7 Shionogi & Co., Ltd.
10.8 Valinor Pharma, LLC

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