Scleroderma Therapeutics Market - Growth, Trends, Covid-19 Impact, and Forecasts (2023 - 2028)

Scleroderma Therapeutics Market - Growth, Trends, Covid-19 Impact, and Forecasts (2023 - 2028)

Scleroderma is a rare and chronic disease that affects around 2.5 million people across the world. The market for scleroderma therapeutics is expected to grow in the near future, owing to the factors, such as the rising prevalence of the disease and the focus of pharmaceutical companies, to come up with novel drugs.

• In United Kingdom, around 19,000 people had been diagnosed with Scleroderma in the year 2018, as stated by Scleroderma & Raynaud’s United Kingdom. In United Kingdom, Scleroderma & Raynaud’s United Kingdom is the only charity, which has been dedicated to improving the lives of people suffering from Scleroderma in the country. Studies have suggested that the prevalence of the disease is more in African Americans, and it is four to nine times higher in women than in men.
• Currently, there has been an improvement in the treatment of scleroderma toward managing complications and providing symptomatic relief. Disease-modifying treatment is widely being investigated for scleroderma, which has been aiming at inhibiting tissue fibrosis and vascular and immune system alterations, which are the three crucial components of disease pathogenesis.
• The upcoming therapies from pharmaceutical companies and future approvals of the same may boost the growth of the market studied.

There is no complete cure for Scleroderma. However, scientists have suggested a few therapies that can be useful for people suffering from this disease. Immunosuppressants are the type of medication that helps reduce the symptoms of scleroderma. As the disease has been associated with the immune system, the immunosuppressants help the same by reducing the immune response from occurring. Immunosuppressors act to trigger the death of immune cells or prevent the production of more immune cells. One of the examples for immunotherapy is rituximab, which reduces the level of B-cells, a type of immune cells involved in the scleroderma.

As of now, immunosuppressants are not approved by the FDA for the treatment of scleroderma but they are given to the patients off-label. Some of the immunosuppressants used for scleroderma include Methotrexate, CellCept, Cytoxan, Imuran, cyclosporin, and Thymoglobulin. Several clinical trials are being done currently to investigate the efficacy of immunosuppressants, and the results of these clinical trials have suggested that immunosuppressants can be beneficial in treating scleroderma.

Hence, with the growing clinical trials and proven efficacy of the immunosuppressants, the market studied is expected to register growth in the future.

North America is expected to hold the largest share for the scleroderma therapeutics market. This has been majorly attributed to the rising number of people suffering from these diseases and the developed healthcare sector, which allows access to novel therapeutics. In United States, organizations, such as Scleroderma Foundation, have been working toward the management of disease and research on the same. As per this foundation, Scleroderma affects about 300,000 people in United States, about one in every thousand. It has been observed that since the last decade, scleroderma has been intensified in United States, therefore, there has been continuous research going on the country for developing a proper treatment for scleroderma. Rising clinical trials that have been resulting in a positive outcome are expected to come up with novel therapies that may boost studied market's growth.

The market for scleroderma therapeutics is moderately competitive, and several big pharmaceutical companies have been involved in the market studied. As there is no curative drug available, these companies have been providing the drugs that reduce the symptoms of the disease. Few companies have their products in the pipeline, and few have been seeking approval from the FDA. With the growing R&D focus of these companies, it is expected that novel therapies may come into the market studied, and the competition may increase in the future.

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