Membrane Chromatography Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)
Membrane chromatography is a well-established technology in bioprocessing that is routinely used in the capture of large particles such as viruses and viral vectors, and also in polishing steps for the removal of DNA, host cell protein impurities (HCP) and virus. There is an increasing demand for biopharmaceuticals and increasing regulatory scrutiny on the cleaning validation of downstream purification processes are the major factors for the growth of this market.
However, the limited use of membrane chromatography in large-scale manufacturing is expected to restrain the growth of this market during the forecast period.
Key Market TrendsIon Exchange Membrane Chromatography is Expected to Cover a Large Share of the MarketIon-exchange chromatography (IC) is a chromatography process that separates ions and polar molecules based on their affinity to the ion exchanger. It works on almost any kind of charged molecule, including large proteins, small nucleotides, and amino acids.
There has been a growing interest in the application of IC in the analysis of pharmaceutical drugs. IC is used in different aspects of product development and quality control testing. In one scuh example, IC is used to improve stabilities and solubility properties of pharmaceutical active drugs molecules as well as used to detect systems that have higher tolerance for organic solvents.IC is also widely used for detection and quantification of excipients or inactive ingredients used in pharmaceutical formulations.
The large share of this segment has been attributed to its wide applications in antibody polishing and virus purification due to the advantages associated with ion exchange membrane chromatography, such as scalability, robustness, disposable nature, high throughput, rapid processing, reduced buffer consumption, and a validation-free environment.
North America is Expected to Dominate the Membrane Chromatography MarketNorth America includes the United States (US), Canada and Mexico. The US and Canada have well structured and development healthcare systems. These countries also promote pharmaceutical research and development and hence have very high expenditure on healthcare. As a result of these policies, many companies globally are encouraged to operate in this region.
Many of the global pharmaceutical players have their headquarters and research labs in the US. As pharmaceutical research requires membrane chromatography, the demand for these technologies and processes is high is North America.This large share can be attributed to the increasing demand for biopharmaceuticals and rising R&D expenditure by biopharmaceutical companies in North America.
Competitive LandscapeThe majority of the membrane chromatography technique and processe instruments are being manufactured by the global key players. Market leaders with more funds for research and better distribution system have established their position in the market. Moreover, Asia-pacific is witnessing an emergence of some small players due to the rise of awareness. This has also helped the market grow.
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