Isothermal Nucleic Acid Amplification Technology (INAAT) Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

Isothermal Nucleic Acid Amplification Technology (INAAT) Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The Isothermal Nucleic Acid Amplification Technology (INAAT) Market is expected to register a CAGR of 11.1% during the forecast period 2022-2027.

COVID-19 is expected to have a significant impact on the growth of the market. The COVID-19 pandemic observed isothermal methods implemented as a basic technology used for the diagnosis of SARS-CoV-2 RNA in home and clinical testing centers. Furthermore, in March 2020, Abbott received the United States Food and Drug Administration approval for the Emergency use of ID NOW COVID-19, an instrument-based, isothermal, rapid system for the qualitative finding of disease. Thus increased utilization during pandemic and product approvals and launches are expected to accelearte the growth of the market during the forecast period.

The increasing incidences of chronic diseases and an aging population, an increase in the adoption of INAAT over PCR, and a rise in demand for low-cost and effective diagnostics procedures are some of the major factors that are driving the growth of the market studied. According to the World Health Organization report in February 2022, Cancer was one of the major cause of death worldwide. The report states that Each year, approximately 400,000 children develop cancer in which cervical cancer is the most common in 23 countries. The report Published by International Agency for Research on Cancer (IARC) in December 2020 that the global cancer burden has risen to 19.3 million cases. and thus, due to the high prevalence of cancer around the world, the demand for effective therapy or treatment is increasing which is expected to drive the growth of the market.

Nucleic acid amplification has several applications in the healthcare industry starting from research to clinics. Until now, PCR has been the most widely-used amplification technology across the world. A thermal cycler is required in PCR, as various temperatures need to be maintained at different steps of the amplification process. Additionally, contaminants must be removed for effective amplification through this technology. The thermal cycler itself is costly, and sample preparation to remove contaminants from the sample makes the overall process more costly and time-consuming.

Owing to this high cost, the technique has witnessed limited adoption in developing countries, where the demand for this technology is extremely high, especially for clinical application. This high demand has led to the development of novel innovative techniques, such as isothermal nucleic acid amplification technology.

The isothermal technique, as the name suggests, is performed at a fixed temperature. This temperature can vary depending on the type of nucleic acid. The tedious task of preparing a sample is not required, as the technology can take a sample directly for amplification. Additionally, the technology is affordable, making it accessible for people belonging to different economic levels across the world. The low-cost associated with technology is likely to result in increased adoption, especially in the developing regions.

Hence, owing to the cost benefits and the use of novel technologies, INAAT market is expected to grow in the coming future.

Key Market TrendsLoop-mediated Isothermal Amplification (LAMP) Segment is Expected to Hold a Major Market Share in the Isothermal Nucleic Acid Amplification Technology (INAAT) Market

Loop-mediated isothermal amplification (LAMP) test is the most widely used technique, and its usage is expected to grow rapidly during the forecast period. In this technique, a minimum of four sets of primers are used, two outer primers and two inner primers. There are various software that are available for primer designing, such as primer explorer, LAMP designer, and other software. These loop primers bind to the nucleic acid template and further accelerate the reaction. The technique can be used for the amplification of both, DNA and RNA.

Since its inception in the early 2000s, LAMP tests have been developed for a variety of disease-causing agents, due to their capability of amplifying both DNA and RNA. Additionally, the tests can be used for the identification of genetically modified organisms.

This technique has two major competitive advantages over PCR technology. First, the LAMP test is tolerant of PCR inhibitors, which makes it well-suited for direct analysis of the sample. Secondly, there is no need of a thermocycler, as it is performed at a fixed temperature. These two advantages make it useful in point-of-care diagnostics. As the market for point-of-care diagnostics is growing, the LAMP segment of the market studied is also likely to grow proportionally.

According to World Ageing 2020 report, people aged 65 years or over in the world is projected to reach to 1.5 billion in 2050. In addition, by 2050, 1 in 6 people in the world will be above 65 years of age,. Thus, owing to above all factors segment is expected to show growth over forecast period.

North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period

North America dominates the Isothermal Nucleic Acid Amplification Technology (INAAT) market, owing to a high incidence of chronic diseases, technological advancement in isothermal nucleic acid amplification technology (INAAT), and increasing adoption of INAAT over conventional techniques in the region.

According to the Centers for Disease Control and Prevention (CDC), in 2020, the total number of Americans with chronic diseases was projected to be approximately 157 million, with 81 million having multiple conditions. Similarly, according to GLOBOCAN 2020, 2,281,658 new cancer cases were diagnosed in the United States in 2020, with 612,390 fatalities.

Also, the Per Capita expenditure on healthcare in North America is also expected to contribute to the growth of the marketr in this region . According to the data published by the United States Department of Commerce in 2021 health spending in Canada is anticipated to reach USD 308 billion. It is estimated that health spending will signify 12.7% of Canada's GDP.

Thus the above mentioned factors are expected to drive the growth of the market in this region during the forecast period.

Competitive Landscape

The Isothermal Nucleic Acid Amplification Technology (INAAT) Market is consolidated in nature and consists of global players such as Becton Dickinson and Company, Qiagen NV, bioMerieux, etc. With the rising use of INAA Technology across developing countries, it is expected that few local players in countries like China, India, etc. will penetrate the market in the near future.

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