Cell Isolation Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)
The market studied is estimated to be USD 8,946.0 million in 2021. It is expected to reach USD 22,929.5 million by 2027, registering a CAGR of 17.09% from 2022 to 2027.
The emergence of COVID-19 had a significant impact on the world. Initially, it had a very negative impact on the research and development activities due to lockdown restrictions, which not only impacted the presence of researchers in laboratories but also impacted the logistics and supply chains of various crucial and necessary laboratory equipment, kits, and reagents, among others. However, with the rapid increase in the infection rate from the SARS-CoV-2 virus, research in the area increased significantly as a number of private and government entities focused their resources on finding a cure for the pandemic, which may have led to the dramatic increase in the demand for the cell isolation product and further, the investment on the research of the long-term effect of COVID-19 is further expected to have a positive impact on the cell isolation market. For instance, in February 2021, the National Institute of Health of the United States launched an initiative worth USD 1.5 billion for over four years to fund investigations of ‘long COVID - the long-lasting health effects of a SARS-CoV-2 infection’. Therefore, the COVID-19 pandemic is expected to significantly impact market growth.
The cell isolation market is expected to have significant growth during the forecast period of the study owing to the high burden and increasing prevalence of chronic diseases such as cancer, cardiovascular diseases, neurological disorders, and others which are driving research and development activities in the area with huge investments and thus, the cell isolation market is expected to grow during the forecast period of the study. For instance, according to the Globocan 2020 report, the global burden of cancer is expected to increase from 19.3 million cases in 2020 to 21.6 million by 2025 and 28.9 million by 2040, and thus, the use of cell separation products is expected to increase over the years for the detection, diagnosis, and administration of proper therapies to the patient which is expected to boost growth in the studied market.
Also, the new investments in biotechnology and life sciences are further expected to have a significant impact on the growth of the studied market as these new investments not only drive the demand for cell isolation products and services but also can lead to advancement in the cell isolation technology with ongoing research activities. For instance, in August 2021, Hyderabad (India)-based Sai Life Sciences, a contract research, development, and manufacturing organization, revealed its plan of investment of about INR 450 crore at its integrated research and development (R&D) campus in Hyderabad by 2023 to expand and enhance its R&D and manufacturing facilities along with other activities.
Furthermore, the technological advancement and innovations in the area of cell isolation or separation are expected to further augment the growth of the studied market as the advancement may not only increase the efficiency of the products but also may reduce their cost, which will lead o greater adoption of cell isolation products like instruments and kits. For instance, in May 2020, Akadeum Life Sciences, Inc. launched mouse naïve CD4+ T cell and mouse naïve T cell negative selection isolation kits, which allow users to perform the entire cell separation process without a column or magnet. Hence, innovations and product launches like these are expected to fuel growth in the cell isolation market during the forecast period.
However, factors such as strict regulations and compliance with cell isolation products by different countries are expected to restrain the growth of the cell isolation market over the forecast period.
Key Market TrendsHuman Cell Segment is Expected to Hold a Significant Market Share in the Cell Isolation Market During Forecast PeriodResearchers utilize isolated cells to understand their biology and develop new cell therapies and other cell-based treatments. Various government bodies across the region have increased their support for the growth of such research activities, owing to their importance. Some of the applications of isolating human cells are conducting molecular analysis of specific cell populations, and isolate immune cells from peripheral blood, preparing a sample of blood separated from plasma, and studying the effects of drug candidates on cell types.
The Akaedeum Human B Cell Isolation Kit was developed with BACS Microbubbles for the enrichment of untouched human B cells. Unwanted cells are depleted through negative selection. EasySep Release Human PE Positive Selection Kit from Stem Cell Technologies is designed to isolate cells that are labeled with PE-conjugated antibodies from fresh or previously frozen peripheral blood mononuclear cells or washed leukapheresis samples by immunomagnetic positive selection.
In May 2022, Akadeum Life Sciences, Inc. announced the expansion of its cell separation product portfolio with a new human B cell isolation product and updated protocol for its existing human isolation kits
In April 2022, Applied Cells Inc. and STEMCELL Technologies, have announced their collaboration to deliver a new high-performance cell separation solution that combines Applied Cells' MARS platform with STEMCELL's EasySep immunomagnetic cell separation kits. This partnership will help researchers around the world to automate and increase the efficiency of isolating high-quality cells from a wide range of sample types such as whole blood, bone marrow, apheresis products, and dissociated tissue. STEMCELL's cell isolation reagents will broaden the applications of the MARS platform and support the specialized requirements of researchers who need to isolate extremely low-frequency cancer cells from human samples. Thus the above-mentioned factors are expected to boost the segment growth.
North America is Expected to Hold a Significant Market Share in the Cell Isolation Market During Forecast PeriodBy geography, the North American region is expected to occupy a significant share in the cell isolation market due to the factors such as the high prevalence of diseases, new investments in the area of life science research and development, and the launch of new products by the market players in the region. For instance, according to the 2021 report of the International Diabetes Federation, the number of people with diabetes living in North America and the Caribbean region is expected to increase from 50.5 million in 2021 to 63 million by 2045, and similarly, the cancer burden in North American region is expected to reach 3.5 million cases by 2040 from 2.6 million in 2020, as per the Globocan 2020 report. Thus, the demand for cell isolation products is anticipated to increase in the North American region for therapeutics and research purposes, fueling growth in the studied market.
In the North American region, the United States is expected to hold a significant share owing to the factors such as the presence of some of the largest pharmaceutical companies in the country, robust life sciences research and development infrastructure, coupled with the high prevalence of chronic diseases in the country. For instance, in May 2022, the University of Texas Medical Branch (UTMB) received USD 56 million grant from the National Institute of Allergy and Infectious Diseases (NIAID). The UTMB has partnered with Novartis, dubbed the UTMB-Novartis Alliance for Pandemic Preparedness (UNAPP), focusing on the coronaviruses, flavivirus, and henipavirus, three major classes of viruses with pandemic potential. Further, the country’s high prevalence of chronic diseases is expected to drive demand for effective and advanced therapeutics, which is further expected to augment growth in the studied market. For instance, according to the American Cancer Society’s 2021 report, about 1.9 million cancer cases (970,250 in males and 927,910 in females) were diagnosed in 2021 in the United States, and 608,570 Americans died from it in 2021. Further, as per the same source, approximately 16.9 million Americans who had a previous history of cancer were alive as of January 1, 2020. Therefore, owing to the high burden of chronic diseases coupled with high investment in life science research and development activities, the United States is expected to hold a major share in the cell isolation market over the forecast period of the study.
Competitive LandscapeThe cell isolation market is competitive and consists of several market players offering advanced products in the area. In terms of market share, a few of the major players are currently dominating the market; these include Becton Dickinson and Company, Merck KgaA, Thermo Fisher Scientific, Bio-Rad Laboratories Inc, Terumo Corporation, and Danaher Corporation, among others.
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