Humanized Mouse and Rat Model Market by Type (Genetic, Cell-Based (CD34, PBMC, BLT)), Application (Neuroscience, Oncology, Toxicology, Immunology & Infectious diseases, Hematopoiesis), End Users, and Region - Global Forecast to 2027

Humanized Mouse and Rat Model Market by Type (Genetic, Cell-Based (CD34, PBMC, BLT)), Application (Neuroscience, Oncology, Toxicology, Immunology & Infectious diseases, Hematopoiesis), End Users, and Region - Global Forecast to 2027

The global humanized mouse and rat model market is projected to reach USD 338 million by 2027 from USD 237 million in 2022, at a CAGR of 7.4% during the forecast period of 2022 to 2027. Currently, immunodeficient mice engrafted with functional human cells, genes, and tissues have emerged as an important tool for the preclinical study of human diseases. Medical testing is done on humanized models as their genetic, biological, and behavioural characteristics resemble those of humans. Also, several medical conditions of humans can be replicated in humanized models and this is promoting market growth. Along with this growth in the humanized mouse and rat model market can be attributed to increased demand for personalized medicine, growing support through investments and grants from the government and private sector, and growth in the number of R&D activities carried out by pharmaceutical and biotechnology companies is driving market growth.

Humanized Rat Model Market is expected to account for the second-largest share for by type segment.

Based on type, the humanized mouse and rat model market has been segmented into humanized mouse models and humanized rat models. In 2021, humanized rat model market accounted for the second largest share. The liver metabolism of rats (in terms of the number and type of liver enzymes) is similar to humans. It is also easy to surgically modify rats and collect samples. The other advantages of rat models include favourable absorption, ease of handling, ability to sustain more intense intravenous dosing, and larger tissue sample. These advantages of rat models over mouse models are encouraging the development of humanized rat models.

The Oncology segment accounted for the highest market share of the application segment in the humanized mouse and rat model market

Based on application, the humanized mouse and rat model market is segmented into oncology, immunology and infectious diseases, neuroscience, haematopoiesis, toxicology, and other applications. In 2021 Oncology application had the highest market share as humanized mouse models have significantly contributed to the understanding of cancer biology, as they are useful in validating gene functions, identifying novel cancer genes & tumor biomarkers, understanding the molecular and cellular mechanisms underlying in tumor initiation, and providing better clinical models to test novel therapeutic strategies.

Europe is the second largest region in the humanized mouse and rat model market

The humanized mouse and rat model market is segmented into North America, Europe, Asia Pacific, Latin America (LATAM) and Middle East and Africa (MEA). After North America, In Europe, the growing pharmaceutical R&D expenditure and growth in the pharmaceutical and biotechnology are major driver for high market share.

The primary interviews conducted for this report can be categorized as follows:

By Respondent: Supply Side- 80% and Demand Side 20%

By Designation: Managers- 55%, CXOs and Director level - 20%, and Executives - 25%

By Region: North America -45%, Europe -30%, Asia-Pacific -20%, Latin America -3%, and Middle East and Africa – 2%

Prominent Players of the humanized mouse and rat model market are Charles River Laboratories International, Inc. (US), The Jackson Laboratory (JAX) (US), Taconic Biosciences, Inc. (US), Crown Bioscience (US), Envigo (US).

Research Coverage:

This report provides a detailed picture of the humanized mouse and rat model market. It aims at estimating the size and future growth potential of the market across different segments such as the type, application, end user and region. The report also includes an in-depth competitive analysis of the key market players along with their company profiles recent developments and key market strategies.

Key Benefits of Buying the Report:

The report will help market leaders/new entrants by providing them with the closest approximations of the revenue numbers for the overall humanized mouse and rat model market and its subsegments. It will also help stakeholders better understand the competitive landscape and gain more insights to better position their business and make suitable go-to-market strategies. This report will enable stakeholders to understand the market's pulse and provide them with information on the key market drivers, restraints, challenges, trends, and opportunities.

The report provides insights on the following pointers:

Analysis of key drivers (Increasing research activities using humanized models, Rising demand for personalized medicine, Continuous support and initiatives from government and private sectors

for cancer research, and Growing R&D activities in pharmaceutical and biotechnology sectors), restraint (High cost of custom humanized models, Laws and regulations for ethical use of animal models in research), opportunities (Rising demand for humanized PDX models, Emergence of CRISPR as a powerful tool in biomedical research, Rising demand for humanized rat models), challenges (Alternatives for animal testing, Limitations of humanized mouse models) are influencing the growth of humanized mouse and rat model market.

Product Development/Innovation: Detailed insights on newly launched product, and technological assessment of the humanized mouse and rat model market.

Market Development: Comprehensive information about lucrative markets – the report analyses the humanized mouse and rat model market across varied regions.

Market Diversification: Exhaustive information about new product, untapped geographies, recent developments, and investments in the humanized mouse and rat model market.

Competitive Assessment: In-depth assessment of market shares, growth strategies and service offerings of leading players like Charles River Laboratories International, Inc. (US), The Jackson Laboratory (JAX) (US), Taconic Biosciences, Inc. (US), Envigo (US), among others in the humanized mouse and rat model market. The report also helps stakeholders understand the pulse of humanized mouse and rat model market and provides them information on key market drivers, restraints, challenges, and opportunities.