Global Light Sheet Microscopy Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Global Light Sheet Microscopy Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Light sheet microscopy, often referred to as single plane illumination microscopy (SPIM), is a rapidly emerging technology that combines optical sectioning with multiple-view imaging to observe tissues and living organisms with impressive resolution. Unlike the conventional techniques of widefield and confocal fluorescence microscopy, the light sheet technique illuminates on the region surrounding the focal plane of the detection objective in a twin objective configuration (where the objectives are juxtaposed at 45-degrees). When compared to conventional microscopy, light sheet methods exhibit reduced photobleaching and lower phototoxicity, and often enable far more scans per specimen. By rotating the specimen, the technique can image virtually any plane with multiple views obtained from different angles. Thus, light sheet microscopy is ideal for examining of both large (animals) and small (cells) specimens labeled with fluorescent proteins and other fluorophores.

Market Overview:

The latest research study on the global Light Sheet Microscopy market finds that the global Light Sheet Microscopy market reached a value of USD 132.12 million in 2022. It’s expected that the market will achieve USD 245.63 million by 2028, exhibiting a CAGR of 10.89% during the forecast period.

Inflation rates generally fall

Affected by the COVID-19 epidemic, the inflation rate has generally declined. Inflation rates in the world’s major economies have fallen, and some economies have experienced deflation. Epidemics and their prevention and control have led to simultaneous reductions in supply and demand in various countries. However, the phenomenon of a general decline in the inflation rate shows that the negative impact on the demand of various countries is even greater. The global macroeconomic situation is usually manifested as insufficient aggregate demand.

Significant reduction in international trade

Affected by the COVID-19 epidemic, international trade has dropped significantly. Affected by economic and trade frictions between China and the United States and trade conflicts between the United States and other countries, global international trade has shrunk in 2019. Affected by the new crown epidemic in 2020, international trade continues to shrink, and the contraction expands significantly. In the first quarter and the second quarter of 2020, the year-on-year growth rate of world exports of goods was -6.4% and -21.3% respectively. Compared with the same period of the previous year, the rate of decline has expanded by 4.0 and 18.1 percentage points respectively.

The unemployment rate has risen significantly

Affected by the COVID-19 epidemic, the unemployment rate has risen significantly. Before the outbreak, the unemployment rate in the world's major economies was at a historically low level. After the outbreak, unemployment rates in many countries have risen significantly. The epidemic rebounded in the autumn and winter of 2020, and the global unemployment situation further deteriorated.

Strength

Light sheet microscopy is the coming-of-age fluorescence imaging technique in fields as diverse as cell and developmental biology, neuroscience, oncology, plant research, high-content screening or biophysics. It enables long-term and large-scale 3D imaging at much higher imaging speed but without the inevitable phototoxicity or photobleaching that occurs when using fluorescence imaging techniques like laser scanning or spinning disk confocal microscopy. In the field of biological imaging technology, mild light sheet microscopy is widely respected.

Weakness

As a high-end biological imaging technology, light sheet microscopy is mainly used in biological and medical research fields. The powerful functions and high price of light sheet microscopy make it unable to replace more traditional imaging methods. In addition, due to the increasing research in the field of life sciences, light sheet microscopy still has some technical difficulties to overcome. Detailed analysis is given in 13.1.1.

Opportunities


With the strengthening of life science research in research fields all over the world, light sheet microscopy will become a good helper for researchers. And government research offices at all levels will increase the adoption of light sheet microscopy, which will promote the development of light sheet microscopy market in the future.

Threat

As light sheet microscopy involves the development of top technology, only a few manufacturers can research and produce light sheet microscopy at present. The development of science and technology is the problem and opportunity faced by light sheet microscopy market. In addition, because the government may adopt control strategies for cutting-edge technologies, it may also affect the development of the market.

Region Overview:

Geographically, Europe held the largest market share – 45.5% in 2021.

Company Overview:

Zeiss is one of the major players operating in the Light Sheet Microscopy market, holding a share of 40.49% in 2021.

Zeiss

ZEISS is one of the world leading manufacturers of microscopes. In addition to excellent light and electron/ion microscopes, ZEISS also offers a broad range of optical sectioning systems as well as high-resolution X-ray microscopes. ZEISS Microscopy is a leading provider of microscope solutions in the life sciences, materials research, routine and industry markets.

Leica

Leica Microsystems develops and manufactures microscopes and scientific instruments for the analysis of microstructures and nanostructures. Ever since the company started as a family business in the nineteenth century, its instruments have been widely recognized for their optical precision and innovative technology. It is one of the market leaders in compound and stereo microscopy, digital microscopy, confocal laser scanning microscopy with related imaging systems, electron microscopy sample preparation, and surgical microscopes.

Segmentation Overview:

As for product types, the SPIM segment held the largest market share in 2021.

Selective Plane Illumination Microscopy (SPIM) is fast and gentle imaging technique that combines the speed of widefield imaging with moderate optical sectioning and low photobleaching. It has become an important fluorescence imaging modality, especially for volumetric imaging.

Light sheet microscopy market also offer light sheet microscopes in several standard configurations including iSPIM, diSPIM, oSPIM, and ct-dSPIM.

Application Overview:

By application, the Developmental Biology segment occupied the biggest share from 2017 to 2022.

Key Companies in the global Light Sheet Microscopy market covered in Chapter 3:

Zeiss
Leica
Bruker
ASI
Olympus Corporation
Miltenyi Biotec
Intelligent Imaging Innovations

In Chapter 4 and Chapter 14.2, on the basis of types, the Light Sheet Microscopy market from 2018 to 2029 is primarily split into:

SPIM
DiSPIM
Other

In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the Light Sheet Microscopy market from 2018 to 2029 covers:

Developmental Biology
Nephrology
Neuronal Morphology
Immunology
Other

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2018-2029) of the following regions are covered in Chapter 8 to Chapter 14:

North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)