Global Dialysis Concentrates Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Global Dialysis Concentrates Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Dialysis concentrate consists of purified water, glucose, and electrolytes, which are used in hemodialysis where the solution is prepared according to the need that helps to regulate electrolyte and remove metabolic waste products. The dialysis concentrate used in dialysis procedure is prepared as per patient requirements, which aids in regulating the electrolyte and maintaining an acid-base balance to facilitate the procedure of removal of metabolic excretes from the body.

Market Overview:

The latest research study on the global Dialysis Concentrates market finds that the global Dialysis Concentrates market reached a value of USD 2182.48 million in 2022. It’s expected that the market will achieve USD 3022.0 million by 2028, exhibiting a CAGR of 5.57% during the forecast period.

COVID-19 is a large family of viruses that causes illness ranging from common cold to more severe respiratory diseases. The COVID-19 pandemic has negatively impacted the industry, as the concern for the transmission of infectious disease during dialysis procedure is high.

The outbreak of COVID-19 has disrupted workflows in the healthcare sector around the world. The disease has forced a number of industries to shut their doors temporarily, including several sub-domains of health care, and thus, there has been an increase in mortality rate among dialysis patients during COVID-19.

In February, 2021, according to a Canadian study published in Canadian Medical Association Journal (CMAJ), patients on long-term dialysis were more than five times likely to be infected with COVID-19 and almost four times more likely to die than the general population. In addition, the concern for the transmission of infectious disease during dialysis procedure is high, which negatively impacted the dialysis concentrate market growth. The survey was conducted in 19 major hospitals in India (8 in the public and 11 in the private sector) to determine the effect of lockdown on the care of patients with kidney disease, including those on dialysis after the first 3 weeks of lockdown. Thus, according to the survey, the number of dialysis patients at these centers decreased from 2,517 to 2,404 from 2019 to 2020. Out of 2,517 patients, around 710 patients (28%) missed one or more dialysis sessions, 69 (3%) needed emergency dialysis, 104 (4%) stopped reporting, and 9 (0.36%) died.

Changes from the Related Industries

Home HD can be performed independently by the patient or with the assistance of a caregiver, allowing a more flexible and convenient option compared to hospital or satellite (henceforth referred to as facility) HD. Home HD also offers the ability to increase the hours and frequency of treatment. Recent data, including those from randomized controlled trials, suggest that the benefits of more frequent dialysis are similar to kidney transplantation, including greater solute clearance, better volume control potentially reducing left ventricular hypertrophy, improved nutrition, and improved quality of life (QoL). Conventional home HD (three times per week, 4–5 h per treatment) is also associated with a number of benefits compared to facility HD including a lower risk of death, improved blood pressure control, higher QoL, and a greater chance of maintaining employment. In contrast, facility dialysis is more restrictive, and hours are generally inflexible with a maximum dialysis duration of 3.5–5 h to accommodate multiple dialysis sessions per machine. Notwithstanding, facility dialysis is substantially more expensive, predominantly due to nursing and technical staff and facility overheads. However, there are reported disadvantages of home HD, including the burden it can impose on caregivers and family members. Concerns also exist regarding the complexity of home HD18 and patient safety while performing unsupervised HD at home.
Home HD offers numerous patient-centered and economic benefits; however, a number of barriers to uptake and maintenance of this treatment also exist; these are addressed in the following sections with a focus on contemporary home HD modalities, including extended hours per week with “short daily” or “nocturnal” home HD.

Substitutes Threat

With the acceleration of the aging of the population and the increase in patients with diabetes and hypertension, the number of patients with acute and chronic renal failure in the world will continue to increase, which will drive the release of market demand for hemodialysis concentrates. The surge in the incidence of kidney disease, problems related to kidney transplantation, and the rising prevalence of lifestyle and chronic diseases are some of the main factors driving the growth of the dialysis concentrate market. At this stage, the rate of hemodialysis treatment is still low, but as the price of hemodialysis medical consumables is drastically reduced, the rate of hemodialysis treatment will continue to increase, and the market for hemodialysis concentrates will be broad in the future. Therefore, the threat of substitution is still relatively small.

Region Overview:

In global comparison, a significant portion of the revenue was generated in North America (37.95% in 2022).

Company Overview:

Fresenius Medical Care is one of the major players operating in the Dialysis Concentrates market, holding a share of 27.18% in 2023.

Fresenius Medical Care

Fresenius Medical Care is a German supplier of dialysis equipment and dialysis services. Its products are mainly used to rescue chronic or acute renal failure. Fresenius Medical Care specializes in dialysis and the treatment of kidney (renal) disease & failure, Haemodialysis and Peritoneal Dialysis.

Nipro

Nipro is a Japanese medical equipment manufacturing company. Founded in 1954, the company is headquartered in Osaka and is listed on the Tokyo Stock Exchange and the Osaka Securities Exchange. As of 2013 the company has 58 subsidiaries in Japan, Asia, North and South America and Europe.

Segmentation Overview:

As for product types, the Acid Concentrates segment held the largest market share in 2022.

Acid Concentrates

Acid concentrate contains acetic acid, citric acid or sodium diacetate to maintain the final dialysate pH. Organic acids from the acid concentrate consume bicarbonate from the bicarbonate concentrate, leading to an equivalent gain of sodium acetate in the final dialysate solution.
Acid concentrates or A-concentrate are acidified concentrate amalgamation of salts which when diluted with dialysis water and bicarbonate concentrates produce fluid that is majorly used to carry out the dialysis process. A-concentrates may contain glucose, and are present in vivid forms of liquid, a dry powder, other high concentrated media, or a mixture of all these.

Bicarbonate Concentrates

Bicarbonate and acid concentrates are mixed with purified water to generate dialysate solution, employed during hemodialysis treatment. During bicarbonate dialysis the bicarbonate dose (or total buffer base dose) that is delivered to the patient is dependent on the concentration gradient for bicarbonate between the dialysate and the plasma water and the efficiency of the dialysis. The change in serum bicarbonate (postdialysis vs. predialysis level) will also depend on the bicarbonate distribution space (estimated at 40–50% of total body weight). Predialysis bicarbonate level will be influenced by factors such as protein intake (due to acid generation in the interdialytic period), use of parenteral nutrition, use of phosphate binders (e.g., calcium carbonate, sevelamer chloride vs. sevelamer carbonate) and other bicarbonate-containing or bicarbonate-forming preparations, as well as gastric acid loss (e.g., from vomiting).
Some of the bicarbonate concentrates might contain sodium carbonate and hence are also known as sodium hydrogen carbonate. Sodium bicarbonate is concentrated in such a way that, when diluted with dialysis water and acid concentrate, it yields fluid for dialysis. These may be in various forms of liquid or dry powder. One of the prominent forms, dry sodium bicarbonate is brought to use in concentrate generators to create a concentrated solution of sodium bicarbonate which is used by dialysis machines to make dialysis fluid.

Application Overview:

By application, the Dialysis Center segment occupied the biggest share from 2018 to 2022.

Key Companies in the global Dialysis Concentrates market covered in Chapter 3:

Weigao group
sansin
Renacon Pharma
Nipro
Rockwell Medical
Medites Pharma
Dialife
B. Braun Melsungen AG
Surni Group
Fresenius Medical Care
Farmasol
Taishikang

In Chapter 4 and Chapter 14.2, on the basis of types, the Dialysis Concentrates market from 2018 to 2029 is primarily split into:

Acid Concentrates
Bicarbonate Concentrates
Others

In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the Dialysis Concentrates market from 2018 to 2029 covers:

Dialysis Center
Home

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2018-2029) of the following regions are covered in Chapter 8 to Chapter 14:

North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)