Global Dextran Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029
Dextran is a non-ionic branched polysaccharide in the form of white powder. It is composed entirely of D-glucose, mainly composed of alpha-1,6-linkages. The molecular weight of dextran is expressed by dividing the molecular weight in Da by 1000. That is, dextran 40 is dextran 40.000 Da (or 40 k Da). Due to its biocompatibility, biodegradability and low toxicity, dextran has a wide range of applications in the life sciences and medical industries.
Market Overview:
The latest research study on the global Dextran market finds that the global Dextran market reached a value of USD 219.85 million in 2022. It’s expected that the market will achieve USD 344.83 million by 2028, exhibiting a CAGR of 7.79% during the forecast period.
Marketing channel sales will be affected differently
The distribution channel segment is divided into offline and online, the offline segment is dominating the market currently, and due to emergence of COVID-19, the online market witnessed a significant growth in 2020. The COVID-19 Outbreak has led to a decline in offline passenger flow, and the advantages of e-commerce companies have become prominent. During the epidemic prevention and control period, some Dextran enterprises did not carry out internet marketing and promotion for their business, so they encountered great resistance in undertaking business. For enterprises that fail to make good use of network promotion means, there is almost no market development during the epidemic period, and the original offline market development plan is disrupted, and the epidemic will face fierce market homogenization competition, which is expected to have a great impact on the company's business throughout the year.
Upstream and downstream interactions will lead to disruption of business
The epidemic will have a short-term impact on Dextran industry, but it is relatively limited. Due to the impact of the epidemic, the production of raw materials and equipment procurement and transportation supply are difficult to be in place, and upstream enterprises affect the work schedule of downstream enterprises. Equipment manufacturing and product manufacturing enterprises in Dextran industry are affected to different degrees, and the production and delivery work may be delayed to some extent. Meanwhile, if it fails to meet the customer's delivery time requirements according to the contract, it may lead to the customer looking for another enterprise and lose business.
The application range of dextran and its derivatives is gradually expanding.
Due to its safety, non-toxicity, and good biocompatibility, dextran can be used as a plasma substitute or a blood tonic, and it is also widely used in organ preservation, thrombosis prevention, eye care, etc. With the in-depth research of dextran by researchers, more and more application fields are gradually developed. In the food industry, it can be used as a stabilizer, moisturizer, thickener and extender for beverage and pastry production. Dextran and its derivatives can also be used as adjuvants, emulsifiers, carriers and stabilizers in cosmetic preparations. In the field of vaccine applications, dextran can be used as a part of the vaccine as a carrier, backbone and/or as a stabilizer for antigens or other subunits. This expanding application field has promoted the development of the dextran market.
Political Factors
Political Factors determine the extent to which a government may influence the economy or a certain industry. Political factors often have an impact on the Dextran industry and how they do business. Manufacturers must meet various regulations promulgated by the government and operate in accordance with government policies. New entrants into the industry must also understand government policies and act in accordance with regulations.
Region Overview:
In global comparison, a significant portion of the revenue was generated in Europe (36.19% in 2022).
Company Overview:
Pharmacosmos is one of the major players operating in the Dextran market, holding a share of 75.23% in 2022.
Pharmacosmos
Pharmacosmos is the leading dextran manufacturer and expert in dextran fractionation techniques. Pharmacosmos offers Pharmaceutical Quality Dextran as active pharmaceutical ingredients (API) as excipient for final formulation, drug product, for medical devices, for production of solutions for injection and infusion and much more.
Jinyang Biological Pharmaceutical
The company's products cover multiple fields such as biological raw materials, pharmaceutical intermediates, pharmaceutical excipients, food additives, and veterinary preparations. Dextran series products are currently the mainstream plasma substitute products in China. With advanced production technology and rich management experience, the company has a high market share in the domestic and foreign markets.
Segmentation Overview:
By type, Pure Dextran segment accounted for the largest share of market in 2022.
Pure Dextran
Dextran is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths, which are used medicinally to reduce blood viscosity and to expand the volume. It was first discovered by Louis Pasteur in wine as a bacterial product, but its use was popularized after further developments by Allene Jeanes. Dextran with varying structures and wide-ranging molecular weights is produced by several microorganisms. It is found in maple syrup, sauerkraut juice, honey, and refined crystalline sugar. It is commercially produced in industries by fermentation of a sucrose-rich medium. The product yield depends on factors, such as temperature, pH, and nitrogen source. It is used as an anti-platelet to reduce blood viscosity and to treat hypovolemia, which can result from severe burns, trauma or injury, surgery, or some other causes of bleeding.
Iron dextran
Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD)-Chronic Kidney Disease patients receiving an erythropoietin.
DEAE-Dextran
Diethylaminoethyl (DEAE)-dextran is a polycationic derivative of the carbohydrate polymer dextran, and it is one of the first chemical reagents used to transfer nucleic acids into cultured mammalian cells.
Dextran Sulfate
Dextran sulfate is an anionic derivative of dextran produced by sulfation of selected dextran fractions. Dextran sulfates are supplied as the sodium salt forms, making them soluble and stable in water.
Application Overview:
The market's largest segment by application is the segment Human Pharmaceuticals , with a market share of 41.03% in 2022.
Human Pharmaceuticals
In human pharmaceuticals application, dextran can be used as a medication used in managing and treating various clinical conditions, including during hemorrhage, shock, surgical procedures, radiological imaging, antithrombotic administration, and ophthalmic relief of xerophthalmia.
Animal Pharmaceuticals
Dextran is used in animal medicine, for example, iron dextran is used worldwide to prevent anemia of piglets by intramuscular injection and to prevent and treat iron deficiency anemia of piglets.
Medical
Medicinally it is used as an antithrombotic (antiplatelet), to reduce blood viscosity, and as a volume expander in hypovolaemia. Dextran is used in some eye drops as a lubricant. and in certain intravenous fluids to solubilize other factors, such as iron (in a solution known as Iron Dextran). Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition.
Cosmetics
In cosmetic preparation, dextran acts as a binding agent that improves dispersion of the components in cosmetic formulations. Another important function is thickening by controlling the viscosity of cosmetic preparations that helps in maintaining appropriate consistency.
Food
Glucan has the characteristics of viscosity increasing, emulsification, organization and stability in food applications. Dextrans have been known for their viscosifying, emulsifying, texturizing, stabilizing attributes in food applications. Dextran has the potential to be recruited as a novel ingredient replacing the commercial hydrocolloids in bakery and other food industries. Prebiotic oligosaccharide production by hydrolysis of dextran is a rather new field, garnering research and industrial attention.
Key Companies in the global Dextran market covered in Chapter 3:
Pharmacosmos
Fina Biosolutions
Guangxi TG Phamaceutical
Spectrum Chemicals
Jinyang Biological Pharmaceutical
Polydex Pharm
tdB Labs
Thermofischer Scientific
SwatiSpentose
Clearsynth
Serumwerk Bernburg
Meito Sangyo
Herbon
Polysciency Inc
PK Chemicals
In Chapter 4 and Chapter 14.2, on the basis of types, the Dextran market from 2018 to 2029 is primarily split into:
Pure Dextran
Iron dextran
DEAE-Dextran
Dextran Sulfate
Others
In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the Dextran market from 2018 to 2029 covers:
Human Pharmaceuticals
Animal Pharmaceuticals
Medical
Cosmetics
Food
Others
Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2018-2029) of the following regions are covered in Chapter 8 to Chapter 14:
North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)
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