Global Chiral Separation Column Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Global Chiral Separation Column Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Chiral separation columns are used to separate enantiomers. Separation of chiral molecules is based upon steriochemistry. These columns have a stationary phase that selectively interacts with one enantiomer over the other. These types of columns are very useful for separating racemic mixtures.

Market Overview:

The latest research study on the global Chiral Separation Column market finds that the global Chiral Separation Column market reached a value of USD 104.21 million in 2022. It’s expected that the market will achieve USD 140.21 million by 2028, exhibiting a CAGR of 5.07% during the forecast period.

The sudden outbreak of the COVID-19 pandemic, which has led to strict lockdown regulations in many countries, has disrupted the import and export of chiral separation column. COVID-19 can affect the global economy in three main ways: directly affecting production and demand, causing supply chain and market disruptions, and financially affecting companies and financial markets. The outbreak of the COVID-19 pandemic will affect the chiral separation column industry in a short period of time. Due to the national blockade, the raw material supply chain has been interrupted or delayed, putting pressure on the product supply of the industry. The convenience of distribution channels requires distributors with smooth logistics and flexibility. However, the pandemic has hit logistics hard, severely impacting the speed of turnaround. Factors such as labor shortages and increased raw material costs will increase production costs and risks. At the same time, under the impact of the capital market, investor confidence has been frustrated, and corporate financing has become more difficult.

In the long term, consumer demand for chiral columns will increase as supply chains and production resume. The pandemic has had a significant impact on the global economy, with sales declining in most industries, but the pharmaceutical industry has seen a significant increase. The severity of the epidemic has made people pay more attention to health and start to take more preventive measures. On the other hand, researchers are using chromatography to try to understand Sars-CoV-2 virus and develop better treatments, vaccines and diagnostic tools to help fight Covid-19. As one of the key equipment of chromatography, chiral chromatographic column has also been further developed.

Drivers

National attention to the development of experimental analysis instrument industry, increasing investment in chromatography, for example, China in the special conditions for the development of scientific research twelfth five-year planning explicitly pointed out that to increase the inspection detection technology and equipment research and development strength, promote the localization process of key equipment, key inspection equipment, speed up the rapid detection equipment, methods of screening, promotion and application. The introduction of national policies has promoted the steady and rapid development of experimental analytical instruments. Chiral column as a segmentation field will undoubtedly benefit from the policy support.

Restraints and Challenges

In the chiral column industry, a high level of professional service is one of the most important factors for customers, and enterprises need to continue to invest in method development. As most customers are not familiar with the selection and use of chromatography columns, they have high requirements for application support services, pre-sales training and after-sales service capabilities (professionalism, experience, scale, rapid response, etc.). At present, although the product technology of some enterprises has reached the level of industrial production and application, but due to the lack of perfect service system, customer service is greatly restricted, and the scale of business is difficult to expand.
Talent is the key to the competition in this industry, and it is crucial to improve the competitiveness of enterprises in key technology research and development, sales channel expansion, technical support and other aspects. Engaged in chiral column industry, the enterprise needs to have many years of professional talent and experience accumulation. At present, the relevant professional and technical personnel are relatively limited, and the talents are mainly gradually cultivated by enterprises in the research and development practice, which costs a lot, thus bringing a high talent barrier to the industry.

Region Overview:

In 2022, the share of the Chiral Separation Column market in United States stood at 33.4%.

Company Overview:

Daicel Corporation is one of the major players operating in the Chiral Separation Column market, holding a share of 43.94% in 2022.

Daicel Corporation

Daicel Corporation is a chemical company based in Japan. It operates business in celluloid technologies, organic chemicals, high-performance chemicals, polymers and pyrotechnic devices. The company's products include cellulose acetate, tow for cigarette filters, high-performance chemicals, engineering plastics like liquid crystal polymers, resin compounds, and automotive airbag inflators.

Merck (Sigma-Aldrich)

Merck is a leading science and technology company in healthcare, life science and performance materials. About 50,000 employees, around the globe, work to further develop technologies that improve and enhance life from biopharmaceutical therapies to treat cancer or multiple sclerosis, cutting-edge systems for scientific research and production, to liquid crystals for smartphones and LCD televisions. Following the acquisition of Sigma-Aldrich, Merck operates in 67 countries.

Segmentation Overview:

As for product types, the Analytical Columns segment held the largest market share in 2022.

Application Overview:

The market's largest segment by application is the segment LC, with a market share of 44.24% in 2022.

GC

Gas chromatography is a term used to describe the group of analytical separation techniques used to analyze volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporized in order to separate the analytes by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyte through the heated column. Gas chromatography is one of the sole forms of chromatography that does not utilize the mobile phase for interacting with the analyte. The stationary phase is either a solid adsorbant, termed gas-solid chromatography (GSC), or a liquid on an inert support, termed gas-liquid chromatography (GLC).

LC

Liquid chromatography is a technique used to separate a sample into its individual parts. This separation occurs based on the interactions of the sample with the mobile and stationary phases. Because there are many stationary/mobile phase combinations that can be employed when separating a mixture, there are several different types of chromatography that are classified based on the physical states of those phases. Liquid-solid column chromatography, the most popular chromatography technique and the one discussed here, features a liquid mobile phase which slowly filters down through the solid stationary phase, bringing the separated components with it.

SFC

When a material is in a state that the temperature and the pressure exceed the critical point, it becomes a supercritical fluid. In this phase, the density of gas and liquid becomes same. Super critical fluid is a special phase which has either gas and liquid character but different from these.

Key Companies in the global Chiral Separation Column market covered in Chapter 3:

Agilent Technologies
Merck (Sigma-Aldrich)
Daicel Corporation
YMC
Regis Technologies
Avantor Performance Materials
Shinwa Chemical Industries
Guangzhou Research and Creativity Biotechnology
Phenomenex

In Chapter 4 and Chapter 14.2, on the basis of types, the Chiral Separation Column market from 2018 to 2029 is primarily split into:

Analytical Columns
Preparative Columns
Semi-prep
Others

In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the Chiral Separation Column market from 2018 to 2029 covers:

GC
LC
SFC
Others

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2018-2029) of the following regions are covered in Chapter 8 to Chapter 14:

North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)