Global Certified Reference Materials (CRMs) Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Global Certified Reference Materials (CRMs) Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029

Certified Reference Materials (CRMs) are ‘controls’ or standards used to check the quality and metrological traceability of products, to validate analytical measurement methods, or for the calibration of instruments. A certified reference material is a particular form of measurement standard.

Market Overview:

The latest research study on the global Certified Reference Materials (CRMs) market finds that the global Certified Reference Materials (CRMs) market reached a value of USD 1742.68 million in 2022. It’s expected that the market will achieve USD 2721.0 million by 2028, exhibiting a CAGR of 7.71% during the forecast period.

Influence of COVID-19 Outbreak on Certified Reference Materials (CRMs) Industry Development

Since the outbreak of the COVID-19 virus in December 2019, the disease has spread to nearly 100 countries around the world, and the World Health Organization has declared it an emergency public health event. The COVID-19 epidemic is infected with a large number of people, and its spread and scope far exceed SARS. At present, the number of confirmed cases in Worldwide has exceeded 18 million. Different industries are affected differently by the epidemic situation.

Some major industrial companies have closed factories and considered the scope of layoffs to help curb the spread of the virus, as well as for economic reasons. This has caused an increase in unemployment and a decrease in come both for individuals and enterprises. Some regions even closed to prevent the virus from spreading. For a technology-intensive industry like the certified reference materials (CRMs), it relies heavily on capital and skilled personnel to conduct research day after day. Affected by the epidemic, people are quarantined at home and not allowed to go out for work, entailing a lower work efficiency for lacking of research facility and environment. More importantly, the economic recession the pandemic cause can only worsen the situation in the progress of CRMs industry, since some businesses may be trapped in fund problem for closing, they may have not so much capital for production or consumption. The normal operation of the industry will also be affected. The raging COVID-19 has left the global economic environment in depression. The impact of COVID-19 on the CRM Industry will involve all major links and all entities in the industry chain. The company's management efficiency has declined, commuting has been severely hindered, production plans have been severely hindered, network expansion has been delayed, marketing has been delayed, brand adjustments have been forced, market sales have declined, and company and employee revenue have declined. The impact on the Wood Pallet Industry depends on the prevention and control effects of COVID-19. This fact will exert a negative impact on the industry.

Regulatory Requirements on labs for higher quality promote the CRM market

As regulatory standards continue to increase, additional responsibility is being placed on laboratories to ensure the quality and safety of finished products. Testing and calibration laboratories, including analytical chemical laboratories, are continually requested to provide evidence on the quality of their operations. This is mandatory in cases where legislative limits are involved, e.g. in international trade, food and environmental analysis, clinical chemistry, etc. Demonstration of adequate quality is required also in research and development activities. While the best way for the laboratory to officially prove its quality, the easiest way is to comply with appropriate international quality standards and obtain formal certification. The certified reference materials play a critical role in quality assurance and contribute to the process of establishing traceability of units used to report laboratory results. Now more than ever, traceability is a major concern. The CRMs offered a solution for laboratories that are required to ensure the reference materials being used for method validation and process controls are fit-for-purpose, homogenous, and stable. Therefore, the growing demand for traceable and reliable lab results promises to drive the market to grow.

Unsatisfactory progress in developing countries

Today's world of modern technology requires a large number of certified reference materials (CRMs) in widely diverse fields. and the application of certified reference materials (CRMs) in analytical chemistry for quality control purposes is well recognized and recommended by a wide range of international, national and professional organizations. However, irrespective of the geographical region or the economic situation in laboratories, current practice in CRM application in many analytical sectors is not adequate. Moreover, the preparation of a CRM is a time-consuming and expensive endeavor, especially in many of the analytical laboratories in developing countries, they lack financial resources, professional personnel, and technological support to produce and experiment the CRM in the process. The budget constraints further restrict the comprehensive use of available CRMs that are largely prepared and commercialized in western countries and restrains the exploration for more applications. Meanwhile, these CRMs are usually expensive for developing countries and have a long purchasing cycle, most of the industries in developing countries use imported from abroad, such as Germany and the United States.

Region Overview:

Geographically, United States held the largest market share – 39.03% in 2022.

Company Overview:

Merck is one of the major players operating in the Certified Reference Materials (CRMs) market, holding a share of 11.7% in 2023.

Merck

Merck & Co., Inc. is a global health care company that delivers health solutions through its prescription medicines, vaccines, biologic therapies, animal health, and consumer care products, which it markets directly and through its joint ventures. The Company has operations in pharmaceutical, animal health, and consumer care.

AgilentAgilent

Agilent Technologies, Inc. provides core bio-analytical and electronic measurement solutions to the communications, electronics, life sciences, and chemical analysis industries. The Company offers electronic and bio-analytical measurement, semiconductor, and board testing.

Segmentation Overview:

Among different product types, Inorganic Type segment is anticipated to contribute the largest market share in 2028.

Organic Type

Organic certification reference materials are produced for GC, GC/MS, LC and LC/MS, including chromatographic standards (whey and solution) and internal standards for qNMR measurement. It has a wide range of uses, including: volatiles, semi-volatile organic compounds, pesticides, petrochemicals, biofuels, drinking water, wine, phthalates, drugs and residual solvents.

Inorganic Type

Inorganic certified reference materials provide comprehensive standards, reagents and reference materials for most inorganic analytical methods, such as pH buffer standard solution, conductivity standard solution, ICP, ICP-MS, AAS and ion chromatography. They are mainly used for the determination of major, minor and trace components in inorganic materials, including the chemical analysis of steel, non-ferrous metals (and their alloys), ceramic and glass soil, and wood and recycled materials.
Source: Maia Research Analysis

Application Overview:

By application, the @@@ segment occupied the biggest share from 2018 to 2022.

Inductively Coupled Plasma

Certified reference materials are calibration standards for Inductively Coupled Plasma (ICP). The ICP is an ionization source that fully decomposes a sample into its constituent elements and transforms those elements into ions. It is typically composed of argon gas, and energy is coupled to it using an induction coil to form the plasma.

Atomic Absorption Spectroscopy

Certified reference materials could be used as standards for Atomic absorption spectrometry (AAS). AAS detects elements in either liquid or solid samples through the application of characteristic wavelengths of electromagnetic radiation from a light source. Individual elements will absorb wavelengths differently, and these absorbances are measured against standards like CRMs. AAS is used primarily to analyze compounds in solution. As such, AAS is used in food and beverage, water, clinical, and pharmaceutical analysis. It is also used in mining operations, such as to determine the percentage of precious metal in rocks.

Chromatography

Certified reference materials are suitable for chromatography. Chromatography is a technique for separating chemical substances that relies on differences in partitioning behavior between a flowing mobile phase and a stationary phase to separate the components in a mixture.

Quantitative NMR

Certified reference materials could be used as internal standards in quantitative NMR studies. Quantitative NMR (qNMR) could solve the task of establishing traceability for organic compounds. As a relative primary method, the big advantage of qNMR is the fact that the signal intensity of the integrals is in direct proportion to the number of hydrogen atoms leading to the signal. The chemical structure of the compound has no influence on the signal intensity. This allows for comparing different compounds quantitatively with high precision.

Key Companies in the global Certified Reference Materials (CRMs) market covered in Chapter 3:

Agilent
Inorganic Ventures
Arconic
Phenomenex
SPEX CertiPrep
Starna Scientific
ATCC
OREAS
Hellma
JRC
Merck (Certipur, Cerilliant, RTC, Supelco)
Paragon Scientific
FLUXANA
LGC

In Chapter 4 and Chapter 14.2, on the basis of types, the Certified Reference Materials (CRMs) market from 2018 to 2029 is primarily split into:

Organic Type
Inorganic Type

In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the Certified Reference Materials (CRMs) market from 2018 to 2029 covers:

Inductively Coupled Plasma
Atomic Absorption Spectroscopy
Chromatography
Quantitative NMR
Others

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2018-2029) of the following regions are covered in Chapter 8 to Chapter 14:

North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)