Global CRYOGENIC ELECTRON MICROSCOPY Market Research Report 2024-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2030

Global CRYOGENIC ELECTRON MICROSCOPY Market Research Report 2024-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2030

Cryogenic Electron Microscopy is a structural biology microscopy technique applied to samples cooled to cryogenic temperatures. It uses high-speed electrons as a source beam to obtain structural information about the biological system under study. Typically, biological samples are embedded in glass ice by snap freezing, and the frozen samples are then viewed and imaged in Cryogenic Electron Microscopy at liquid nitrogen temperatures. Cryogenic Electron Microscopy enables scientists to make detailed 3D images of DNA, RNA, proteins, viruses, cells, and the tiny molecular machines inside cells, revealing how they change shape and interact in complex ways as they carry out living functions. Cryogenic Electron Microscopy is used together with X-ray crystallography and nuclear magnetic resonance to determine the structure of macromolecules to improve imaging quality and form the basis for high-resolution structural biology research.

Market Overview:

The latest research study on the global CRYOGENIC ELECTRON MICROSCOPY market finds that the global CRYOGENIC ELECTRON MICROSCOPY market reached a value of USD 523.58 million in 2023. It’s expected that the market will achieve USD 842.65 million by 2029, exhibiting a CAGR of 8.25% during the forecast period.

Increase in downstream applications

Because cryo-electron microscopy has the characteristics of high resolution, closer to the natural state, and a wide range of applicable research objects, more and more scientists have begun to use cryo-electron microscopy as a new research direction. Cryo-EM has significant advantages in structural biology. Previous structural biology techniques include X-ray crystallography and NMR spectroscopy. The application of both methods is limited due to the large sample size required. X-ray crystallography also requires sample crystallization, a difficult process that transforms the environment into a non-physiological one. Cryo-EM does not require large sample sizes or crystallization and is therefore suitable for structural visualization at near-atomic resolution. The method also has the advantage of not requiring chemical fixation or staining of the samples, which means they can be studied in their natural physiological environment. Furthermore, structures can be snap-frozen into multiple conformations, allowing inferences about biological mechanisms, without the constraints of crystals locking samples into static poses. Consequently, cryo-electron microscopy is increasingly used for structural analysis of proteins and other biomolecules at the atomic scale in various applications in life science research. The rapid development of cryo-EM technology has promoted the progress of structural biology, and there will be more and more industrial applications in the development of antibody therapeutics, small molecule drugs, and diagnostics. Among them, single-particle cryo-electron microscopy is superior to traditional techniques in terms of remodeling proteins and RNA.

In the field of energy storage batteries, cryo-EM plays an important role because conventional techniques cannot capture the nanoscale changes in morphology and structure that have an important impact on the stability and performance of perovskite solar cells. In the field of catalysis, the combination of cryo-electron microscopy and cryo-transmission electron microscopy has revealed the formation process of solvent structures in catalyst inks for scientists. In addition, based on cryo-electron microscopy technology, new drug discovery, and computing will also usher in breakthroughs. Therefore, with the further improvement and maturity of cryo-electron microscopy technology, downstream applications continue to increase.

Increase in government health spending

As the disposable income of people in every country increases, so does the global healthcare expenditure. To meet population needs, government agencies, and healthcare institutions are actively accelerating healthcare spending. The increase in medical spending also helps medical institutions improve treatment facilities for various diseases that have become very prevalent in recent years. The increasing prevalence of chronic diseases such as cancer, Alzheimer's, and cardiovascular disease has created a need for advanced imaging techniques such as cryo-electron microscopy. With its ability to study the structure of disease-causing proteins, cryo-electron microscopy promises to be an invaluable tool in the fight against these diseases. Rising healthcare spending is also conducive to the progressive growth of the economy and the healthcare industry. It has been productive because it has significantly influenced the development of better and more advanced treatment options for various drugs and other therapeutic products. Furthermore, the adoption of technologically advanced cryo-electron microscopy has increased in various academic and research institutions, and funding for advanced microscopy R&D has increased substantially in developing countries such as China, India, and Brazil.

Region Overview:

In 2022, the share of the CRYOGENIC ELECTRON MICROSCOPY market in North America stood at 36.43%.

Company Overview:

Thermo Fisher Scientific is one of the major players operating in the CRYOGENIC ELECTRON MICROSCOPY market, holding a share of 90.68% in 2023.

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of over $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD.

JEOL

Company business includes Manufacturing, marketing, development & research of Scientific and Metrology Instruments (Electron Optics Instruments, Analytical Instruments, Measuring Instruments), Semiconductor Equipment, Industrial Equipment, and Medical Equipment, processing, maintenance & services of related products and parts, as well as procurement & sales of peripherals.

Segmentation Overview:

By type, 300kV Cryogenic Electron Microscopy segment accounted for the largest share of market in 2022.

Application Overview:

By application, the Biological Science segment occupied the biggest share from 2018 to 2022.

Key Companies in the global CRYOGENIC ELECTRON MICROSCOPY market covered in Chapter 3:

JEOL
Hitachi
Thermo Fisher Scientific

In Chapter 4 and Chapter 14.2, on the basis of types, the CRYOGENIC ELECTRON MICROSCOPY market from 2019 to 2030 is primarily split into:

300kV Cryogenic Electron Microscopy
200kV Cryogenic Electron Microscopy
120kV and Other Cryogenic Electron Microscopy

In Chapter 5 and Chapter 14.3, on the basis of Downstream Industry, the CRYOGENIC ELECTRON MICROSCOPY market from 2019 to 2030 covers:

Biological Science
Material Science
Others

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2019-2030) of the following regions are covered in Chapter 8 to Chapter 14:

North America (United States, Canada)
Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden)
Asia Pacific (China, Japan, South Korea, Australia, India, Indonesia, Philippines, Malaysia)
Latin America (Brazil, Mexico, Argentina)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa)