Global Prokaryotic Expression System Market Growth (Status and Outlook) 2025-2031

The global Prokaryotic Expression System market size is predicted to grow from US$ 509 million in 2025 to US$ 702 million in 2031; it is expected to grow at a CAGR of 5.5% from 2025 to 2031.

The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms.For overproduction of recombinant proteins both eukaryotic and prokaryotic expression systems are used. Choosing the right system depends, among other things, on the growth rate and culture of host cells, level of the target gene expression and posttranslational processing of the synthesized protein. Regardless of the type of expression system, its basic elements are the vector and the expression host. The most widely used system for protein overproduction, both on a laboratory and industrial scale, is the prokaryotic system. This system is based primarily on the bacteria E. coli, although increasingly often Bacillus species are used. The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms. The simplicity of genetic modifications and the availability of many bacterial mutants are additional advantages of the prokaryotic system. In this article we characterize the structural elements of prokaryotic expression vectors. Also strategies for preparation of the target protein gene that increase productivity, facilitate detection and purification of recombinant protein and provide its activity are discussed. Bacterial strains often used as host cells in expression systems as well as the potential location of heterologous proteins are characterized. Knowledge of the basic elements of the prokaryotic expression system allows for production of biologically active proteins in a short time and in satisfactory quantities.

The global prokaryotic expression system market refers to the market for systems and tools used for the expression of proteins in prokaryotic organisms, such as bacteria. Prokaryotic expression systems are widely used in biotechnology and pharmaceutical research for the production of recombinant proteins. The market is driven by several factors. Firstly, the increasing demand for recombinant proteins for research, diagnostics, and therapeutics drives the demand for prokaryotic expression systems. These systems allow for the efficient production of proteins in large quantities, which is essential for various applications in the life sciences. Secondly, the advancements in genetic engineering technologies have led to the development of improved prokaryotic expression systems. These systems enable the expression of complex proteins and facilitate the incorporation of post-translational modifications, enhancing the functionality of the produced proteins. Additionally, the growing investment in biotechnology and pharmaceutical research is fueling the demand for prokaryotic expression systems. Research organizations and pharmaceutical companies are actively engaged in discovering and developing new drugs and biological therapies that rely on recombinant proteins. Prokaryotic expression systems play a vital role in the production of these proteins. Furthermore, the increasing prevalence of chronic diseases, such as cancer and autoimmune disorders, has led to a rise in the demand for protein-based therapeutics. Prokaryotic expression systems offer a cost-effective and scalable solution for the production of these therapeutic proteins. Geographically, the market for prokaryotic expression systems is spread across regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America dominates the market due to the presence of a well-established biotechnology and pharmaceutical industry. Europe and Asia Pacific follow closely, with significant investments in research and development activities.

LPI (LP Information)' newest research report, the “Prokaryotic Expression System Industry Forecast” looks at past sales and reviews total world Prokaryotic Expression System sales in 2024, providing a comprehensive analysis by region and market sector of projected Prokaryotic Expression System sales for 2025 through 2031. With Prokaryotic Expression System sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Prokaryotic Expression System industry.

This Insight Report provides a comprehensive analysis of the global Prokaryotic Expression System landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on Prokaryotic Expression System portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Prokaryotic Expression System market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Prokaryotic Expression System and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Prokaryotic Expression System.

This report presents a comprehensive overview, market shares, and growth opportunities of Prokaryotic Expression System market by product type, application, key players and key regions and countries.

Segmentation by Type:
Fungi
Cell
Others

Segmentation by Application:
Biotech
Medicine
Laboratory
Others

This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the company's coverage, product portfolio, its market penetration.
Agilent Technologies, Inc.
Bio-Rad Laboratories, Inc.
QIAGEN
Promega Corporation.
Thermo Fischer Scientific, Inc.
Life Technologies Corporation.
Takara Bio Inc.
GenScript
New England Biolabs.
OXFORD EXPRESSION TECHNOLOGIES LTD
LifeSensors, Proteogenix
Synthetic Genomics Inc.
Peak Proteins Ltd
ProMab, Sino Biological Inc.
Lucigen
ARTES Biotechnology GmbH
Jena Bioscience GmbH
BIONEER CORPORATION
LenioBio.
Lonza.

Please note: The report will take approximately 2 business days to prepare and deliver.