Global Polyhydroxyalkanoate (PHA) Market Growth 2025-2031

Global Polyhydroxyalkanoate (PHA) Market Growth 2025-2031

The global Polyhydroxyalkanoate (PHA) market size is predicted to grow from US$ 201 million in 2025 to US$ 367 million in 2031; it is expected to grow at a CAGR of 10.5% from 2025 to 2031.

Polyhydroxyalkanoate (PHA) is a storage material for carbon and energy sources in microorganisms. When carbon sources are abundant and other nutrients (N/P/S, etc.) are insufficient, they will be synthesized in different microorganisms. PHA synthesis the main costs are the substrate cost in the fermentation stage and the cost of downstream extraction and purification.

The diversity of PHA monomer structure is mainly different from the difference in the side chain group on the C-3 position, in which the monomer with 3-5 carbon atoms is short-chain PHA (SCL PHA), and the number of carbon atoms above 6 is medium and long chain. PHA (MCL PHA). In the general structural formula of PHA, R can be an alkenyl group, a benzene ring, an alkyl group, etc., usually m is 1, and n represents the degree of polymerization, which determines the molecular weight of the polymer. Poly-3-hydroxybutyric acid (PHB) with a methyl side chain is the most common. Poly-3-hydroxybutyric acid (PHB) has thermoplasticity like polypropylene and has brittleness and poor thermal stability; polyhydroxybutyric acid-co-hydroxyvaleric acid copolymer (PHBV) has more good strength, hardness, greater elasticity, lower melting point. Short-chain PHA presents a hard crystal; medium- and long-chain PHA is a thermoplastic elastomer with good flexibility, low hardness, slow crystallization rate, and the melting temperature is mostly kept in the range of 39-61 °C; short-chain medium- and long-chain copolymerization The PHA (SCL-MCL PHA), by adjusting the monomer ratio, obtains a copolymerized PHA material that combines the excellent properties of short-chain and medium-long chains. PHA synthesis methods include microbial fermentation (wild bacteria method, recombinant engineering bacteria method), transgenic plant method, activated sludge method, and microbial fermentation method are the main ways of biosynthesizing PHA at present. The microorganisms that synthesize PHA are mainly divided into three categories: pure bacteria, engineering bacteria and mixed bacteria. In the process of biosynthesizing PHA, there are disadvantages such as high sterilization cost, high consumption of fresh water, and easy contamination by discontinuous fermentation, resulting in lower competitiveness of industrial biotechnology compared with chemical processes.

There are two methods of synthesis of PHA: biosynthesis and chemical synthesis.

Biosynthesis:

①Bacterial synthesis method: Different microorganisms can convert different fermentation substrates into PHA under suitable conditions.

② Genetic engineering method: introduce the relevant enzymes of Alcaligenes eutrophic bacteria that synthesize PHB into oil plants to obtain transgenic plants, and clone and synthesize PHB from the cells or plastids of these transgenic plants. The genetic method saves the separation and purification steps of PHB and bacteria in the bacterial method, which can reduce the synthesis cost, but the low yield and the difficulty of purification seriously restrict the large-scale production and application of PHA.

③Activated sludge method: Activated sludge is a bacterial mass containing a large number of active microorganisms and a small number of impurities and contains a large amount of biologically active substances and organic substances. The specific process is taking the remaining activated sludge from the sewage plant and put it into the SBR reactor. After the sludge is in good condition, the color changes from brown to light yellow, and the activity is stable, it enters the next cycle of domestication process, and finally discharges a batch of the activated sludge rich in PHA can be extracted by PHA, and then a new batch of excess sludge can be added again and repeat steps 1 to 3 to obtain high-yield PHA sludge in batches.

Chemical synthesis method:

①the bond between the carbonyl group in the lactone ring and the oxygen atom is broken, and there are few racemates in the product.

②the bond between the β-carbon atom and the oxygen atom in the lactone ring is broken, and the enantiomer can be racemized.

According to the number of carbon atoms in the PHA monomer, PHA can be divided into two categories:

1. According to the number of carbon atoms in the PHA monomer, PHA can be divided into two categories

①Short chain: the number of carbon atoms is 3-5, such as PHB, PHV.

②Medium and long chain: the number of carbon atoms is 6-14, such as PHHx, PHO

2. According to the different types of monomers, PHA can be divided into two categories

①Homopolymer, the number of monomers is 1, such as PHB, PHV.

②Copolymer, the number of monomers is greater than or equal to 2, such as PHBHHx, PHBV

At present, the main ones commercialized on the market are PHB, PHBV, P34HB, and PHBHHx

Global key manufacturers of Polyhydroxyalkanoate (PHA) include Danimer Scientific, Kaneka, Nafigate Corporation, Tian"an Biopolymer, Biomer, etc. Global top five manufacturers hold a share about 85%. Europe is the largest market of Polyhydroxyalkanoate (PHA), holds a share over 55%. In terms of product, PHBHHxpoly(3-hydroxybutyrate-co-3-hydroxyhexanoate) holds a share of over 80%. And in terms of application, the largest application field is Food Services, with a share of over 35%.

LP Information, Inc. (LPI) ' newest research report, the “Polyhydroxyalkanoate (PHA) Industry Forecast” looks at past sales and reviews total world Polyhydroxyalkanoate (PHA) sales in 2024, providing a comprehensive analysis by region and market sector of projected Polyhydroxyalkanoate (PHA) sales for 2025 through 2031. With Polyhydroxyalkanoate (PHA) sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Polyhydroxyalkanoate (PHA) industry.

This Insight Report provides a comprehensive analysis of the global Polyhydroxyalkanoate (PHA) landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Polyhydroxyalkanoate (PHA) portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Polyhydroxyalkanoate (PHA) market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Polyhydroxyalkanoate (PHA) and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Polyhydroxyalkanoate (PHA).

This report presents a comprehensive overview, market shares, and growth opportunities of Polyhydroxyalkanoate (PHA) market by product type, application, key manufacturers and key regions and countries.

Segmentation by Type:
PHB-Poly(3-hydroxybutyrate)
PHBV-poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
P34HB-poly(3-hydroxybutyrate-co-4-hydroxybutyrate)
PHBHHxpoly(3-hydroxybutyrate-co-3-hydroxyhexanoate)

Segmentation by Application:
Packaging
Biomedical Implant
Agricultural
Food Services
Others

This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Danimer Scientific
Kaneka
Nafigate Corporation
Tian'an Biopolymer
Biomer
Shenzhen Ecomann Technology
RWDC Industries
Newlight Technologies
CJ CheilJedang
PHB Industrial S.A.
Mango Materials

Key Questions Addressed in this Report

What is the 10-year outlook for the global Polyhydroxyalkanoate (PHA) market?

What factors are driving Polyhydroxyalkanoate (PHA) market growth, globally and by region?

Which technologies are poised for the fastest growth by market and region?

How do Polyhydroxyalkanoate (PHA) market opportunities vary by end market size?

How does Polyhydroxyalkanoate (PHA) break out by Type, by Application?

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