Global Organ On Chip Market Growth (Status and Outlook) 2025-2031

The global Organ On Chip market size is predicted to grow from US$ 153 million in 2025 to US$ 821 million in 2031; it is expected to grow at a CAGR of 32.4% from 2025 to 2031.

An Organ-On-Chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-On-Chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels. The primary focus of Organ-On-Chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney). In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.

Global main manufacturers of organ-on-chip include Emulate, Mimetas and TissUse, etc. The top three players hold a share about 40%. The global organ-on-chip is mainly produced in United States and Europe, they occupied for a share over 80%. North America is the largest market, has a share about 43%, followed by Europe and Japan, with share 37% and 8%, separately.

LPI (LP Information)' newest research report, the “Organ On Chip Industry Forecast” looks at past sales and reviews total world Organ On Chip sales in 2024, providing a comprehensive analysis by region and market sector of projected Organ On Chip sales for 2025 through 2031. With Organ On Chip sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Organ On Chip industry.

This Insight Report provides a comprehensive analysis of the global Organ On Chip landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on Organ On Chip portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Organ On Chip market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Organ On Chip and breaks down the forecast by Type, by End User, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Organ On Chip.

This report presents a comprehensive overview, market shares, and growth opportunities of Organ On Chip market by product type, application, key players and key regions and countries.

Segmentation by Type:
Brain-on-a-chip
Liver-on-a-chip
Kidney-on-a-chip
Lung-on-a-chip
Heart-on-a-chip
Intestine-on-a-chip
Vessel-on-a-chip
Other Organs

Segmentation by End User:
Pharmaceutical & Biotechnology Companies
Academic & Research Institutes
Cosmetics Industry
Others

This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the company's coverage, product portfolio, its market penetration.
Emulate
Mimetas
TissUse
Valo Health
CN Bio Innovations
Hesperos
Draper Laboratory
Nortis
Micronit Microtechnologies B.V.
Kirkstall
Cherry Biotech SAS
Else Kooi Laboratory
Altis Biosystems
Bi/ond
Netri
Xona Microfluidics
SynVivo, Inc.
Beijing Daxiang Biotech

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