Global Molybdenum-99 and Technetium-99m Market Growth 2025-2031

The global Molybdenum-99 and Technetium-99m market size is predicted to grow from US$ 359 million in 2025 to US$ 482 million in 2031; it is expected to grow at a CAGR of 5.1% from 2025 to 2031.

Molybdenum-99 (Mo-99) is the parent of Technetium-99m (Tc-99m), the most widely applied isotope in nuclear medicine diagnostics today. Its short 6-hour half-life and the amount of emitted energy (140 keV) make Tc-99m a perfect imaging agent. Mo-99 is essential in Technetium generator manufacturing.

The Mo-99 market is characterized by high supplier concentration. Major producers such as NRG, IRE, ANSTO, NTP Radioisotopes, and Rosatom dominate the market. These companies leverage high-flux reactors and sophisticated processing facilities to produce Mo-99, which is then distributed globally. In 2023, the world's top five vendors accounted for 91.15 % of the revenue. This concentration can create vulnerabilities in the supply chain, particularly when technical or regulatory issues arise at key facilities.

Geographically, North America are the largest consumer of Mo-99, holding a market share of 51.64% in 2023. The U.S., despite its lack of domestic Mo-99 production since the late 1980s, remains a major importer of this isotope from countries such as Australia, Canada, Europe, and South Africa. Europe follows as the second-largest market with a 22.23% share, while the Asia-Pacific, particularly China, is emerging as the fastest-growing market.

One of the most significant trends affecting the Mo-99 market is the global transition from highly enriched uranium (HEU) to low-enriched uranium (LEU) in production processes. This shift is driven by international agreements aimed at reducing the proliferation risks associated with HEU. The United States, a major consumer of Mo-99, has been at the forefront of this transition, initiating the conversion of reactors and associated facilities from HEU to LEU since the late 1970s. By 2017, the U.S. officially excluded Mo-99 produced with HEU from its market, a move that was met with considerable response from major Mo-99 producers.

The global transition from HEU to LEU in Mo-99 production is set to be completed by 2026.

This transition has led to a significant increase in the production of Mo-99 using LEU. As of 2023, Mo-99 produced with LEU accounted for 94.48% of the global market. And the market segment for LEU-based Mo-99 is expected to continue expanding, which will occupy the entire market.

Looking ahead, the Molybdenum-99 (Mo-99) market is poised for significant evolution driven by several key trends. Technological advancements in reactor design and isotope processing will enhance production efficiency and safety, while innovations in waste management, such as Synroc® technology, address environmental concerns. Regulatory changes, particularly those related to non-proliferation and environmental protection, will continue to influence production practices. Moreover, the expanding healthcare infrastructure in developing regions, especially in APAC, will drive increased demand for Mo-99, presenting substantial growth opportunities.

With ongoing investments in technology and infrastructure, coupled with a focus on sustainability, the Mo-99 market is poised for continued growth and development in the coming years.

LP Information, Inc. (LPI) ' newest research report, the “Molybdenum-99 and Technetium-99m Industry Forecast” looks at past sales and reviews total world Molybdenum-99 and Technetium-99m sales in 2024, providing a comprehensive analysis by region and market sector of projected Molybdenum-99 and Technetium-99m sales for 2025 through 2031. With Molybdenum-99 and Technetium-99m sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Molybdenum-99 and Technetium-99m industry.

This Insight Report provides a comprehensive analysis of the global Molybdenum-99 and Technetium-99m landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Molybdenum-99 and Technetium-99m portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Molybdenum-99 and Technetium-99m market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Molybdenum-99 and Technetium-99m and breaks down the forecast by Production Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Molybdenum-99 and Technetium-99m.

This report presents a comprehensive overview, market shares, and growth opportunities of Molybdenum-99 and Technetium-99m market by product type, application, key manufacturers and key regions and countries.

Segmentation by Production Type:

Produced by HEU

Produced by LEU

Segmentation by Application:

Medical Imaging

Others

This report also splits the market by region:

Americas

United States

Canada

Mexico

Brazil

APAC

China

Japan

Korea

Southeast Asia

India

Australia

Europe

Germany

France

UK

Italy

Russia

Middle East & Africa

Egypt

South Africa

Israel

Turkey

GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.

NRG

IRE

ANSTO

NTP

Rosatom

Key Questions Addressed in this Report

What is the 10-year outlook for the global Molybdenum-99 and Technetium-99m market?

What factors are driving Molybdenum-99 and Technetium-99m market growth, globally and by region?

Which technologies are poised for the fastest growth by market and region?

How do Molybdenum-99 and Technetium-99m market opportunities vary by end market size?

How does Molybdenum-99 and Technetium-99m break out by Production Type, by Application?

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