Global Transfer Membrane Market Size, Share & Industry Trends Analysis Report By Product, By Application (Western Blotting, Southern Blotting, Northern Blotting and Others), By End-User, By Regional Outlook and Forecast, 2022 - 2028

Global Transfer Membrane Market Size, Share & Industry Trends Analysis Report By Product, By Application (Western Blotting, Southern Blotting, Northern Blotting and Others), By End-User, By Regional Outlook and Forecast, 2022 - 2028

The Global Transfer Membrane Market size is expected to reach $418.9 Million by 2028, rising at a market growth of 4.7% CAGR during the forecast period.

The term "transfer membrane" describes a group of systems that control how ions and other solutes travel across biological membranes composed of lipid bilayers with embedded proteins. Proteins must be moved from the gel onto a suitable membrane for antibody staining and detection when electrophoresis is finished. The transfer is accomplished by running a current from the gel to the membrane. Transfer membrane has many benefits, including improved staining properties, the ability to be tested repeatedly, and compatibility with a range of detection chemistries, such as radioactive, chromogenic, chemiluminescent, fluorescent, and chemifluorescent methods.

Transfer membranes are the solid phase support employed in blotting procedures to transfer proteins or nucleic acids from gel matrices for detection and analysis. Proteins or nucleic acids are immobilized on a solid matrix membrane after size separation by electrophoresis in a polyacrylamide or agarose gel. This makes it easier to identify certain proteins or nucleic acids using antibodies specific to the target of interest.

Blotting is a method for immobilizing proteins or nucleic acids on a solid substrate, often nylon or nitrocellulose membranes. The primary methodology for hybridization research is nucleic acid blotting. Various experimental approaches to investigate gene expression, organization, etc., are based on the labeling and hybridization of nucleic acids on membranes.

With complicated biological mixes like blood, identifying and quantifying particular proteins has long been a crucial objective in science and medical practice. In recent years, clinical research and genetic counseling have increasingly emphasized the detection of aberrant genes in genomic DNA. Protein and nucleic acid sequences that are distinct are found using blotting methods. They have evolved into crucial molecular biology and clinical research instruments due to their development into susceptible and specialized devices.

COVID-19 Impact Analysis

The international economy was negatively impacted by the pandemic, which led to numerous markets collapsing under the weight of lockdown regulations. As a result of lockdown regulations, numerous research and development projects were halted during the COVID-19 pandemic, which harmed the transfer membrane business. The transfer membrane market was kept alive by research on creating coronavirus vaccines. Still, the market witnessed a downward growth trend in the initial phase of the pandemic.

Market Growth Factors

Increasing prevalence of hereditary and infectious disorders

Despite some recent positive attempts, governments typically do not emphasize controlling genetic illnesses and congenital anomalies (EMR). There are severe misunderstandings that these problems are uncommon and cannot be controlled. According to WHO, around 2% to 5% of all live births are affected by genetic illnesses and congenital anomalies, accounting for up to 30% of pediatric hospital admissions and over 50% of infant fatalities in developed nations. Contrary to popular opinion, congenital and genetic illnesses are at least as prevalent in the area as in more developed parts of the world.

Growing need for RNA-based medicines

A fast-developing area of biotherapeutics is RNA Therapeutics. These treatments are built on a strong, adaptable foundation that offers almost limitless potential to meet unmet clinical requirements. The standard of treatment for numerous illnesses will alter due to RNA Therapeutics. There are an increasing number of RNA medications under research and clinical studies. The fast expansion of RNA treatments results from the issues with delivery, immunogenicity, and stability being resolved. While each area has potential for additional development and invention, the solutions have evolved to the point where RNA Therapies are now practicable.

Market Restraining Factors

Availability of a variety of blotting method substitutes

Spectroscopic isofocusing, proteins are sorted by isoelectric point rather than by size in capillary isofocusing. In other words, the protein will cease migrating when it reaches the pH corresponding to its pI since a pH gradient has been generated throughout the gel. This approach has the advantages of greater resolution, quicker sample analysis, and sample preservation. That is why, the availability of the other alternatives and their advantages are expected to hinder the market expansion of the transfer membrane.

Product Outlook

Based on product, the transfer membrane market is segmented into PVDF, nitrocellulose and nylon. The PDVF segment dominated the transfer membrane market with maximum revenue share in 2021. This is because it provides a very reliable and chemically inert alternative to other membranes. PVDF transfer membranes make it simpler to strip and re-probe proteins. These membranes' hydrophobic structure allows them to interact strongly with proteins, enhancing protein binding and facilitating effective transport. Because of PVDF transfer membranes' benefits, their goods are widely used, which aids in boosting the segment's growth.

Transfer Method Outlook

On the basis of transfer method, the transfer membrane market is divided into wet or tank transfer, semi-dry electro blotting (semi-dry transfer), dry electro blotting (dry transfer) and others. The semi-dry electro blotting (semi-dry transfer) segment procured a substantial revenue share in the transfer membrane market in 2021. This is because this technique uses horizontal cassette assemblies, which are made up of transfer buffer-soaked filters, pre-wetted membranes, filter paper, and gel. The approach is beneficial since it uses less transfer buffer and can swiftly transfer proteins to membranes at room temperature.

Sample Type Outlook

By sample type, the transfer membrane market is classified into western blotting, southern blotting, northern blotting and others. The western blotting segment witnessed the largest revenue share in the transfer membrane market in 2021. This is due to the widespread use of the method for clinical and diagnostic tests. High sensitivity and specificity for protein identification are two benefits of western blotting that make it useful as an analytical tool. Moreover, the method can precisely identify a single target protein among more than 300,000 other proteins, considerably enhancing its use in exploratory research applications.

End User Outlook

Based on the end-user, the transfer membrane market is bifurcated into biopharmaceutical & pharmaceutical companies, academic & research institutes and diagnostic labs. The academic & research institutes segment recorded a significant revenue share in the transfer membrane market in 2021. This is due to the robust government backing and extensive research findings readily accessible in industrialized nations. In addition, the growing penetration of blotting methods among reputable academic research institutes is anticipated to increase the prospects for transfer membranes to generate income in the following years.

Regional Outlook

Region-wise, the transfer membrane market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region generated the highest revenue share in the transfer membrane market in 2021. This is owing to the volume of R & D activities, major financial expenditures made in developing new pharmaceuticals, and support provided by both public and commercial entities for research. Moreover, the increased incidence of chronic illnesses and specific diseases in the area is projected to boost the region's development. These factors are anticipated to impact the transfer membrane market's expansion in the projected period.

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., Danaher Corporation, Bio-Rad Laboratories, Inc., Merck KGaA, PerkinElmer, Inc., Abcam Plc, Santa Cruz Biotechnology, Inc., ATTO Corporation, Azure Biosystems, Inc., and GVS S.p.A.

Strategies Deployed in Transfer Membrane Market

Oct-2022: Thermo Fisher Scientific revealed Gibco CTS DynaCellect magnetic separation system. The system features cell isolation, activation and depletion. DynaCellect separate the right cells and minimize failures in manufacturing. The launch is aimed at providing a scalable, flexible, automated and closed system for cell therapy manufacturing.

Jan-2022: Thermo Fisher completed its acquisition of PeproTech, a recombinant proteins provider. With this acquisition, the company aimed to expand its capabilities in order to meet the rising demand for gene therapy and the growth of the cell market. In addition, this acquisition would also complement the cell culture media products of Thermo Fisher through the addition of applications. PeproTech's recombinant proteins offering, which would allow Thermo Fisher to offer substantial benefits to its customers via an integrated portfolio.

Jun-2021: Danaher completed the acquisition of Aldevron, a US-based biotech business. With this acquisition, Danaher would expand its abilities into the crucial field of genomic medicine and help consumers and their essential task to obtain more life-saving treatments and vaccines to market quickly.

May-2021: PerkinElmer took over Nexcelom Bioscience, a Massachusetts-based biotechnology company. Under this acquisition, the integration would broaden PerkinElmer's efforts to support the government, academic, and biopharmaceutical organizations in developing their comprehensive workflows and help efforts to boost time to market and time to target other beneficial therapies.

Jul-2020: Merc expanded its footprint by opening a lab in Shanghai. M Lab Collaboration Center provides customizable solutions made for the Life Science community in China to help advance drug development.

Apr-2020: Bio-Rad Laboratories took over Celsee, an instruments and consumables provider. With this acquisition, the company aimed to expand its reach throughout the world in order to meet the rising demands of customers for single-cell analysis and precision medicine in order to offer improved insight into the disease along with its diagnosis as well as treatment.

Feb-2018: PerkinElmer, Inc. took over RHS Limited, develops and markets biotechnology technologies. Through this acquisition, the company aimed to expand its genomic research offerings.

Scope of the Study

Market Segments covered in the Report:

By Product

• PVDF
• Nitrocellulose
• Nylon

By Transfer Method

• Dry Electro Blotting (Dry Transfer)
• Semi-dry Electro Blotting (Semi-dry Transfer)
• Wet or Tank Transfer
• Others

By Application

• Western Blotting
• Southern Blotting
• Northern Blotting
• Others

By End-User

• Biopharmaceutical & Pharmaceutical Companies
• Academic & Research Institutes
• Diagnostic Labs

By Geography

• North America
• US
• Canada
• Mexico
• Rest of North America
• Europe
• Germany
• UK
• France
• Russia
• Spain
• Italy
• Rest of Europe
• Asia Pacific
• China
• Japan
• India
• South Korea
• Singapore
• Malaysia
• Rest of Asia Pacific
• LAMEA
• Brazil
• Argentina
• UAE
• Saudi Arabia
• South Africa
• Nigeria
• Rest of LAMEA

Companies Profiled

• Thermo Fisher Scientific, Inc.
• Danaher Corporation
• Bio-Rad Laboratories, Inc.
• Merck KGaA
• PerkinElmer, Inc.
• Abcam Plc
• Santa Cruz Biotechnology, Inc.
• ATTO Corporation
• Azure Biosystems, Inc.
• GVS S.p.A

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