Global Regenerative Medicine Market Analysis & Forecast to 2025; Stem Cells, Tissue Engineering, BioBanking & CAR-T Industries
This report provides a comprehensive overview of the size of the regenerative medicine market, segmentation of the market (stem cells, tissue engineering and CAR-T therapy), key players and the vast potential of therapies that are in clinical trials. Kelly Scientific analysis indicates that the global regenerative medicine market was worth $35 billion in 2019 and will grow to over $124 billion by 2025, with a CAGR of 23.3% between this time frame. Within this market, the stem cell industry will grow significantly at a CAGR of over x% and reach $x billion by 2025. Tissue engineering is forecast to grow at a CAGR of x% to 2025 and potentially reach $x billion. This report describes the evolution of such a huge market in 15 chapters supported by over 350 tables and figures in 700 pages.
- An overview of regenerative medicine that includes: stem cells, allogenic and autogenic cells, umbilical cord blood banking, tissue engineering and CAR T therapies.
- Global regenerative medicine market, global breakdown, application breakdown and leading market players
- Detailed account of the stem cell industry market by geography, indication and company profiles
- Profiles, marketed/pipeline products, financial analysis and business strategy of the major companies in this space
- Focus on current trends, business environment, pipeline products, clinical trials, and future market forecast for regenerative medicine
- Insight into the challenges faced by stakeholders, particularly about the success vs. failure ratios in developing regenerative medicine drugs and therapies.
- Insight into the biobanking industry globally and its impact on the overall market
- Description and data for the prevalence of disease types that are addressed by regenerative medicine, stem cells, tissue engineering and CAR-T therapies
- Financial market forecast through 2023 with CAGR values of all market segments outlined in the objective
- SWOT analysis of the global market
- Geographical analysis and challenges within key topographies including the USA, Japan, South Korea, China and Europe
- 1.0 Report Synopsis
- 1.1 Objectives of Report
- 1.2 Executive Summary
- 1.2 Key Questions Answered in this Report
- 1.3 Data Sources and Methodology
- 2.0 Introduction
- 2.1 Gurdon and Yamanaka Share the Nobel Prize
- 2.2 Stem Cell Clinical Trials: Initiated in 2010
- 2.3 Types of Stem Cells
- 2.4 Adult (Tissue) Stem Cells
- 2.5 Pluripotent Stem Cells
- 2.6 Somatic Cell Nuclear Transfer (SCNT)
- 2.7 Induced pluripotent Stem Cells (iPSC)
- 2.8 Mesenchymal Cells
- 2.8.1 MSCs in the Bone Marrow Stroma
- 2.8.2 Isolation, Marker Specificity and Functional Properties of MSCs
- 2.8.3 Oxygen Concentration and MSC Culture
- 2.8.4 Assays to Define MSCs
- 2.8.5 Differentiation Potential of MSCs
- 2.8.6 Therapeutic Potential of MSCs
- 2.8.7 Mesenchymal Stem Cells & Chronic Disease
- 2.8.8 MSCs and Amylotrophic Lateral Sclerosis
- 2.8.9 MSCs and Parkinson’s Disease
- 2.8.10 MSCs and Alzheimer Disease
- 2.8.11 MSCs and Rheumatoid Arthritis
- 2.8.12 MSCs and Type 1 Diabetes
- 2.8.13 MSCs and Cardiovascular Disease
- 2.9 Hematopoietic Stem and Progenitor Cells
- 2.9.1 In Vivo Assays for Hematopoietic Stem Cells
- 2.9.2 In Vitro Assays for Hematopoietic Stem and Progenitor Cells
- 2.9.3 Isolation of Hematopoietic Stem and Progenitor Cells
- 2.9.4 Culture of Hematopoietic Cells
- 2.9.5 Therapeutic uses of Hematopoietic Cells
- 2.10 Umbilical Cord Stem Cells
- 2.11 Heart Stem Cells
- 2.11.1 Cutting Edge Research in Heart Stem Cells
- 2.12 Mammary Stem Cells
- 2.12.1 Defining the Mammary Stem Cell
- 2.12.2 Influence of Model System on Stem Cell Identification
- 2.12.3 Breast Cancer Stem Cells
- 2.13 Neural Stem Cells
- 2.13.1 Identification of Neural Stem Cells
- 2.13.2 Function of Neural Stem Cells in Vivo
- 2.13.3 Neural Stem Cell Culture Systems
- 2.13.4 Isolation Strategies for Neural Stem Cells
- 2.13.5 Brain Tumour Stem Cells
- 2.13.6 Cutting Edge Research in Neural Stem Cells
- 2.14 Stem Cell Applications in Retinal Repair
- 2.14.1 Embryonic Stem Cells as Retina Therapeutics
- 2.14.2 Induced Pluripotent Stem Cells as Retina Therapeutics
- 2.14.3 Adipose Derived Mesenchymal Stem Cells as Retina Therapeutics
- 2.15 Liver Stem Cells
- 2.16 Gut Stem Cells
- 2.16 Pancreatic Stem Cells
- 2.17 Epidermal Stem Cells
- 3.0 Stem Cells and Clinical Trials
- 3.1 Introduction
- 3.2 Pluripotent Stem Cells
- 3.3 Limbal Stem Cells
- 3.4 Neural Stem Cells
- 3.5 Endothelial Stem or Progenitor Cells
- 3.6 Placental Stem Cells
- 3.7 Why Do Stem Cell Clinical Trials Fail?
- 3.8 What is the Future of Stem Cell Trials?
- 3.9 Cutting Edge Stem Cell Clinical Trials
- 3.10 Ocata Therapeutics Current Stem Cell Trials
- 3.11 CHA Biotech Current Stem Cell Trials
- 3.12 Pfizer Current Stem Cell Trials
- 3.13 GSK Current Stem Cell Trials
- 3.14 Bayer Current Stem Cell Trials
- 3.15 Mesoblast International Current Stem Cell Trials
- 3.16 Millennium Pharmaceutical Current Stem Cell Trial
- 3.17 AstraZeneca Current Stem Cell Trials
- 3.18 Merck Current Stem Cell Trials
- 3.19 Chimerix Current Stem Cell Trials
- 3.20 Eisai Current Stem Cell Trials
- 3.21 SanBio Current Stem Cell Trials
- 3.22 Celgene Current Stem Cell Trials
- 3.23 StemCells Current Stem Cell Trials
- 3.24 Genzyme (Sanofi) Current Stem Cell Trials
- 3.25 Teva Current Stem Cell Trials
- 3.26 MedImmune Current Stem Cell Trials
- 3.27 Janssen Current Stem Cell Trials
- 3.28 Seattle Genetics Current Stem Cell Trials
- 3.29 Baxter Healthcare Current Stem Cell Trials
- 3.30 InCyte Corp Current Stem Cell Trials
- 4.0 Stem Cells, Disruptive Technology, Drug Discovery & Toxicity Testing
- 4.1 Introduction
- 4.2 Case Study: Genentech and Stem Cell Technology
- 4.3 3D Sphere Culture Systems
- 4.4 Stem Cells and High Throughput Screening
- 4.4.1 Embryonic Stem Cells
- 4.4.2 Adult Stem Cells
- 4.4.3 Opportunities & Challenges
- 4.5 Genetic Instability of Stem Cells
- 4.6 Comprehensive in Vitro Proarrhythmia Assay (CiPA) & Cardiomyocytes
- 4.8 Coupling Precise Genome Editing (PGE) and iPSCs
- 4.9 Stem Cells & Toxicity Testing
- 4.9.1 Hepatotoxicity and iPSCs
- 4.9.2 Cardiotoxicity and iPSCs
- 4.9.3 Neurotoxicity and iPSCs
- 4.10 Stem Cell Disease Models
- 4.11 Defining Human Disease Specific Phenotypes
- 4.11.1 Molecular Phenotypes for Disease Modelling
- 4.11.2 Cellular Phenotypes for Disease Modelling
- 4.11.3 Physiological Phenotypes for Disease Modelling
- 4.11.4 Parkinson’s Disease
- 4.11.5 Alzheimer’s Disease
- 4.11.6 Amyotrophic Lateral Sclerosis
- 4.11.7 Huntington’s Disease
- 4.11.8 Spinal Muscular Atrophy
- 4.11.9 Down Syndrome
- 4.11.10 Cystic Fibrosis
- 4.11.11 Colorectal Cancer
- 4.12 Advantages of Stem Cell Derived Cells & Tissues for Drug Screening
- 5.0 Stem Cell Biomarkers
- 5.1 Pluripotent Stem Cell Biomarkers
- 5.2 Mesenchymal Stem Cell Biomarkers
- 5.3 Neural Stem Cell Biomarkers
- 5.4 Hematopoietic Stem Cell Biomarkers
- 6.0 Manufacturing Stem Cell Products
- 6.1 Manufacturing Strategies For Stem Cell Products
- 6.2 BioProcess Economics for Stem Cell Products
- 6.3 Capital Investment
- 6.4 Cost of Goods
- 6.5 Bioprocess Economic Drivers & Strategies
- 6.6 hPSC Expansion & Differentiation using Planar Technology
- 6.7 hPSC Expansion using 3D Culture
- 6.8 Microcarrier Systems
- 6.9 Aggregate Suspension
- 6.10 Bioreactor Based Differentiation Strategy
- 6.11 Integrated hPSC Bioprocess Strategy
- 6.12 GMP Regulations and Stem Cell Products
- 7.0 Investment & Funding
- 7.1 What do Investors Want from Cell & Gene Therapy Companies?
- 7.2 What Makes a Good Investment?
- 7.3 What Types of Companies do Not Get Investment?
- 7.4 Global Funding
- 7.5 Cell & Gene Therapy Investment Going Forward
- 7.6 What Cell & Gene Companies are the Most Promising in 2018?
- 7.7 Insights into Investing in Cell and Gene Therapy Companies
- 8.0 Regenerative Medicine Market Analysis & Forecast to 2025
- 8.1 Market Overview
- 8.2 Global Frequency Analysis
- 8.3 Economics of Regenerative Medicine
- 8.4 Market Applications & Opportunities for Regenerative Therapies
- 8.4.1 Neurological Disease
- 8.4.2 Autoimmune Disorders
- 8.4.3 Cardiovascular Disease
- 8.4.4 Diabetes
- 8.4.5 Musculoskeletal Disorders
- 8.4.6 Ocular Disease
- 8.4.7 Orthopedic Disorders
- 8.4.8 Wound Healing
- 8.5 Global Financial Landscape
- 8.6 Regenerative Medicine Clinical Trial Statistics
- 8.7 Regenerative Medicine Market Forecast to 2025
- 8.8 Regenerative Medicine Geographic Analysis and Forecast to 2025
- 8.9 Regenerative Medicine Geographical Location of Companies
- 8.10 Regenerative Medicine Technology Breakdown of Companies
- 8.11 Commercially Available Regenerative Medicine Products
- 8.12 Major Regenerative Medicine Milestones
- 9.0 Stem Cell Market Analysis & Forecast to 2025
- 9.1 Autologous & Allogenic Cell Market Analysis
- 9.2 Stem Cell Market by Geography
- 9.2.1 North America
- 9.2.2 Asia/Pacific
- 9.2.3 Europe
- 9.3 Stem Cell Market Forecast by Therapeutic Indication
- 9.3.1 Orthopedic/Musculoskeletal Stem Cell SubMarket
- 9.3.2 Cancer Stem Cell SubMarket
- 9.3.3 Cardiology/Vascular Stem Cell SubMarket Analysis
- 9.3.4 Wound Healing Stem Cell SubMarket Analysis
- 9.3.5 Skin Stem Cell SubMarket Analysis
- 9.3.6 Ocular Stem Cell SubMarket Forecast
- 9.4 Stem Cell Reagent Market Trends
- 10.0 Tissue Engineering Tissue Engineering Market Analysis and Forecast to 2025
- 10.1 Geographical Analysis and Forecast to 2025
- 10.1.1 North America
- 10.1.2 Europe
- 10.1.3 Asia Pacific
- 10.2 Geographical Analysis by Company Share
- 10.3 Tissue Engineering Clinical Indication Analysis & Forecast to 2025
- 10.3.1 Orthopedic and Musculoskeletal
- 10.3.2 Oncology
- 10.3.3 Cardiology and Vascular
- 10.3.4 Dermatology
- 10.3.5 Oral and Dental
- 11.0 Biobanking Market Analysis
- 11.1 Increasing Number of Cord Blood Banks Globally
- 11.2 Global Biobanking Company Sector Analysis & Breakdown
- 11.3 Allogenic Versus Autologous Transplant Frequency
- 11.4 Biobanking Market Analysis & Forecast to 2025
- 11.5 Major Global Players
- 12.0 Global Access & Challenges of the Regenerative Medicine Market
- 12.1 Regenerative Medicine Market in the USA
- 12.2 Regenerative Medicine in Japan
- 12.2.1 Financial Investment
- 12.2.2 Unconventional Company Investment in Regenerative Medicine
- 12.3 Regenerative Medicine in China
- 12.4 Regenerative Medicine in South Korea
- 13.0 Cell and CAR T Therapy
- 13.1 Challenges Relating to Cell therapy and Chimeric Antigen Receptor T Cells in Immunotherapy
- 13.1.1 Clinical Status of CD19 CAR-T Cells To Date
- 13.1.2 Clinical and Regulatory Challenges for Development of CAR T Cells
- 13.1.3 Key Regulatory Challenges Associated with CAR-T Development
- 13.1.4 Summary of Select CAR-T Products by Juno, Novartis and Kite
- 13.1.5 Clinical Benefit Versus Toxicity in CD19-Directed ALL Clinical Trials
- 13.1.6 How to Manage Toxicity of CAR-T Therapy
- 13.2 Regulations Pertaining to Immunotherapy, including Adoptive Cell Therapy (CAR-T and TCR) Immunotherapy Regulation in the USA
- 13.2.1 Center for Biologics Evaluation and Research (CBER)
- 13.2.2 Compliance and Surveillance
- 13.2.3 Extra Resources on Immunotherapeutics from the FDA
- 13.2.4 Cellular, Tissue and Gene Therapies Advisory Committee
- 13.2.5 Consumer Affairs Branch (CBER) Contact in FDA
- 13.2.6 FDA Regulations Pertaining to Immunotherapies
- 13.2.7 Case Study Ovarian Cancer Immunotherapy Regulations
- 13.2.7.1 Efficacy
- 13.2.7.2 Adverse Effects
- 13.2.8 Trial Design Considerations for Immunotherapy
- 13.2.9 Development of Immune-Related Response Criteria (irRC) & Clinical Endpoints Specific to Immunotherapies
- 13.3 Regulations for Cell Therapy & Immunotherapy in Japan
- 13.3.1 PMDA and Cell Therapy & Immunotherapy
- 13.3.2 Increasing the Efficiency in Cell Therapy & Immunotherapy Regulatory Review
- 13.3.3 Forerunner Review Assignment System
- 13.3.4 Revised Guidelines for Clinical Evaluation of Anti‐Malignant Tumor Agents
- 13.3.5 Key Contacts Within the PMDA for Cell Therapy & Immunotherapeutics
- 13.4 European Regulation and Cell Therapy & Immunotherapeutics
- 13.4.1 Introduction
- 13.4.2 Challenges for Cell Therapy & Immunotherapy in EMEA
- 13.4.3 EMA Status on Potency Testing
- 13.4.3.1 In Vivo Potency Testing
- 13.4.3.2 In Vitro Potency Testing
- 13.4.3.3 Viable Cell Count
- 13.4.3.4 Autologous Cell Based Products
- 13.4.3.5 Reference Preparation
- 13.4.3.6 Adjuvant Containing Immunotherapy Products
- 13.4.4 EMA Status on Identifying hyper, Hypo or non-Responders
- 13.4.5 Challenges Relating to Biomarkers in Immunotherapy
- 13.4.6 Challenges Relating to Chimeric Antigen Receptor T Cells in Immunotherapy
- 13.4.7 Estimating Optimal Cut-Off Parameters
- 13.4.8 EU-Approved Immunotherapies in Melanoma
- 13.4.9 Key Contacts Within EMA for Cell Therapy & Immunotherapeutics
- 13.5 Manufacturing of Immunotherapies
- 13.5.1 Introduction
- 13.5.2 Generation of CAR-Modified T Cells
- 13.5.3 What Co-Stimulation and Activity Domain is Optimal to Use?
- 13.5.4 Optimizing Cell Culture Media
- 13.5.5 Manufacturing Lentiviral Vectors
- 13.5.6 Detection of Integrated CAR-Expressing Vectors
- 13.5.7 Donor Lymphocyte Infusion Procedure
- 13.5.8 Ex Vivo Costimulation & Expansion of Donor T Cells
- 13.5.9 Infusion to the Patient
- 13.5.10 Manufacturing Devices and Instruments Required for Immunotherapy Production
- 13.5.10.1 Leukapheresis
- 13.5.10.2 Cell Counters and Analyzer
- 13.5.10.3 Cell Seeding, Growth and Propagation
- 13.5.11 Good Manufacturing Procedure (GMP) for Immunotherapy
- 13.5.12 Case Study Production of Lentivirus Induced Dendritic Cells under GMP Conditions
- 13.5.13 Quality Control
- 13.5.14 Regulatory Affairs
- 13.5.15 Key Challenges in Manufacturing
- 13.5.15.1 Electroporation of T-cells
- 13.5.15.2 Allogenic CAR T cells
- 13.5.15.3 Relapse Rates are Critical
- 13.5.15.4 Antigen Negative Relapse
- 13.5.15.5 Incorporating Suicide Genes
- 13.5.16 Automation in Cell Therapy Manufacturing
- 13.5.17 Autologous Cell Therapy Manufacture Scale Up
- 13.6 Supply Chain & Logistics
- 13.6.1 Introduction
- 13.6.2 Case Study: Juno Therapeutics
- 13.7 Pricing & Cost Analysis
- 13.7.1 Introduction
- 13.7.2 CAR T Therapy Market Evaluation
- 13.7.3 Current Deals Within the CAR T Market
- 13.8 CAR-T Therapy and Solid Tumors
- 13.8.1 Challenges for Solid Tumors
- 13.8.1.1 Off-Tumor Toxic Responses
- 13.8.1.2 Poor Penetration to Tumor Site
- 13.8.1.3 Increasing Therapeutic Efficiency
- 13.8.2 Avoiding Immunosuppression within Tumor Microenvironment
- 13.8.3 Clinical Trials Show Promise
- 14.0 Company Profiles
- 14.1 Astellas Institute for Regenerative Medicine (Ocata Therapeutics)
- 14.1.1 Company Background
- 14.1.2 Products
- 14.1.3 Financials
- 14.1.4 Company Strategy
- 14.2 Athersys
- 14.2.1 Company Background
- 14.2.2 Products
- 14.2.3 Financial Analysis
- 14.2.4 Company Strategy
- 14.3 Baxter International (Baxalta, Shire)
- 14.3.1 Company Background
- 14.3.2 Financial Analysis
- 14.3.3 Company Strategy
- 14.4 Caladrius Biosciences (NeoStem)
- 14.4.1 Company Details
- 14.4.2 Products
- 14.4.2.1 CLBS20
- 14.4.2.2 CLBS03 Treg Cellular Therapy
- 14.4.2.3 CLBS12 CD34 Cell Therapy
- 14.4.3 Financial Analysis
- 14.4.4 Company Strategy
- 14.5 Cynata Therapeutics
- 14.5.1 Company Background
- 14.5.2 Product Details
- 14.5.3 Financial Data
- 14.5.4 Company Strategy
- 14.6 Cytori Therapeutics
- 14.6.1 Company Products
- 14.6.2 Financial Analysis
- 14.6.3 Company Strategy
- 14.7 MEDIPOST
- 14.7.1 Company Details
- 14.7.2 Company Products
- 14.7.2.1 CellTree Umbilical Cord Blood Bank
- 14.7.2.2 CARTISTEM®
- 14.7.2.3 NEUROSTEM®
- 14.7.2.4 PNEUMOSTEM ®
- 14.7.3 Financial Analysis
- 14.8 Mesoblast
- 14.8.1 Company Details
- 14.8.1.1 Unique Features of Mesoblast and its Disruptive Technology
- 14.8.1.2 Allogeneic Mesenchymal Lineage Adult Stem Cells (MLCs)
- 14.8.1.3 Mechanism of Action of MLC Products
- 14.8.1.4 Manufacturing of Mesoblast MLC-Based Products
- 14.8.1.5 Mesoblast Patent Portfolio
- 14.8.2 Mesoblast Product Portfolio
- 14.8.2.1 MSC-100-IV/TEMCELL® for Acute Graft Versus Host Disease (aGVHD)
- 14.8.2.2 MPC-150-IM - Chronic Heart Failure (CHF)
- 14.8.2.3 MPC-25-IC for Acute Myocardial Infarction
- 14.8.2.4 MPC-06-ID - Chronic Low Back Pain (CLBP) due to Degenerative Disc Disease (DDD)
- 14.8.2.5 MPC-300-IV for Biologic-Refractory Rheumatoid Arthritis
- 14.8.2.6 MPC-300-IV for Diabetic Nephropathy
- 14.8.2.7 MPC-100-IV for Crohn’s Disease
- 14.8.2.8 MPC-25-Osteo for Spinal Fusion
- 14.8.3 Mesoblast International Strategic Business Collaborations
- 14.8.4 Mesoblast Financial Analysis
- 14.9 NuVasive
- 14.9.1 Company Details
- 14.9.2 Biologic Products for the Spinal Surgery Market
- 14.9.2.1 Formagraft
- 14.9.2.2 AttraX
- 14.9.2.3 Propel DBM
- 14.9.2.4 Osteocel Plus and Pro
- 14.9.3 Financial Analysis
- 14.9.4 Company Business Strategy
- 14.10 Osiris Therapeutics
- 14.10.1 Company Profile
- 14.10.1.1 BioSmart Cryopreservation Technology
- 14.10.1.2 MSC Primer Technology
- 14.10.2 Products
- 14.10.2.1 Grafix
- 14.10.2.2 BIO 4
- 14.10.2.3 Cartiform
- 14.10.2.4 Stravix
- 14.10.3 Company Financial Analysis
- 14.10.4 Company Strategy
- 14.11 Plasticell
- 14.11.1 Company Profile
- 14.12 Pluristem Therapeutics
- 14.12.1 Company Profile
- 14.12.2 Products
- 14.12.2.1 PLacental eXpanded (PLX) Cells
- 14.12.2.2 PLX-PAD
- 14.12.2.3 PLX-R18
- 14.12.3 Financial Analysis
- 14.12.4 Business Strategy
- 14.13 Pfizer
- 14.13.1 Company Profile
- 14.14 StemCells Inc
- 14.14.1 Company Profile
- 14.14.2 HuCNS-SC Platform Technology
- 14.14.3 Clinical Trial Analysis
- 14.14.4 Financial Analysis
- 14.15 STEMCELL Technologies
- 14.15.1 Company Details
- 14.15.2 Product Details
- 14.16 Takara Bio
- 14.16.1 Company Details
- 14.16.2 Product Portfolio
- 14.16.2.1 HF10 Anti-Cancer Therapy
- 14.16.2.2 TCR Gene Therapy
- 14.16.2.3 MazF Gene Therapy
- 14.16.3 Centre for Cell and Gene Processing
- 14.16.4 Company Financials
- 14.16.5 Company Strategy
- 14.17 Tigenix
- 14.17.1 Company Background
- 14.17.2 Products
- 14.17.3 Financial Data
- 14.17.4 Company Strategy
- 15.0 SWOT Industry Analysis
- 15.1 What has Strengthened the Industry Thus Far?
- 15.2 Allogenic and Autologous Stem Cell Industry SWOT Analysis
- 15.3 What are the Main Driving Forces of this Space?
- 15.4 Restraints of the Regenerative Medicine Industry as a Whole
- 15.5 Industry Opportunities Within this Sector
- 15.6 USA SWOT Analysis
- 15.6.1 Growth Opportunities
- 15.6.2 Drivers
- 15.6.3 Market Challenges
- 15.7 UK SWOT Analysis
- 15.7.1 Growth Opportunities
- 15.7.2 Drivers
- 15.7.3 Market Challenges
- 15.8 South Korea SWOT Analysis
- 15.8.1 Growth Opportunities
- 15.8.2 Drivers
- 15.8.3 Market Challenges
- 15.9 China SWOT Analysis
- 15.9.1 Growth Opportunities
- 15.9.2 Drivers
- 15.9.3 Challenges
- 15.10 Japan SWOT Analysis
- 15.10.1 Opportunities
- 15.10.2 Market Drivers
- 15.10.3 Challenges
- 15.11 Singapore SWOT Analysis
- 15.11.1 Opportunities
- 15.11.2 Market Drivers
- 15.11.3 Challenges
- List of Exhibits
- Exhibit 2.1 Stem Cell Discovery and Development Timeline
- Exhibit 2.2 Potential Therapeutic Uses of Stem Cells
- Exhibit 2.3 Embryonic Stem Cell Differentiation
- Exhibit 2.4 Pluripotent Stem Cells
- Exhibit 2.5 Clinical Uses of Stem Cells
- Exhibit 2.6 Illustration of Inner Cell Mass Generation for Stem Cell Culture
- Exhibit 2.7 Drug Development Strategies for Patient Derived iPSCs
- Exhibit 2.8 Mesenchymal Stem Cell Lineage Progression & Differentiation
- Exhibit 2.9 Mesenchymal Stem Cell Differentiation
- Exhibit 2.10 Potential Therapeutic Effects of MSCs
- Exhibit 2.11 Hematopoietic Stem Cells & the Formation of Mature Blood Cells
- Exhibit 2.12 Donor Types for HSC transplantation
- Exhibit 2.13 Total Number of Stem Cell Donors 1989-Present
- Exhibit 2.14 Cross Section of Umbilical Cord Sample for Stem Cell Extraction
- Exhibit 2.15 Umbilical Cord Blood and Wharton’s Jelly; Sources of HSCs and MSCs
- Exhibit 2.16 Comprehensive List of Conditions Treated by Cord Blood Transplants
- Exhibit 2.17 Cardiac Progenator Cell Populations
- Exhibit 2.18 Transplanted Cardiac Progenitor Cells: Potential Mechanism of Action in the Myocardium
- Exhibit 2.19 Mammary Stem Cells in the Presence and Absence of Hormones
- Exhibit 2.20 Mammary Stem Cell Tree Following Transplantation
- Exhibit 2.21 Production of Neurons, Astrocytes and Oligodendrocytes from Neural Stem Cells
- Exhibit 2.22 Physiology of the Eye
- Exhibit 2.23 Physiological Functions of Each Eye Component
- Exhibit 2.24 Healthy & Degenerated Retinal Pigment Epithelium
- Exhibit 2.25 Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium
- Exhibit 2.26 Using Stem Cells to Replace Dysfunctional Retinal Pigment Epithelial Cells
- Exhibit 2.27 Using Stem Cells to Replace Retinal Nerve Cells
- Exhibit 2.28 Stem Cells Located Around the Central Vein in the Liver
- Exhibit 2.29 Gut Stem Cells are Located in the Crypts of Lieberhahn
- Exhibit 2.30 Localization of Epidermal & Dermal Stem Cells
- Exhibit 3.1 Current Therapeutic Areas and Disease States with Number of Stem Cell Clinical Trials, Globally
- Exhibit 3.2 Current Geographical Location and Number of Stem Cell Clinical Trials, Globally
- Exhibit 3.3 Current Geographical Location and Number of Stem Cell Clinical Trials, USA
- Exhibit 3.4 Current Geographical Location and Number of Stem Cell Clinical Trials, Europe
- Exhibit 3.5 Current Geographical Location and Number of Stem Cell Clinical Trials, East Asia
- Exhibit 3.6 Select hESC and iPSC-Based Products in Clinical Trials by Disease, Stage and Trial Status
- Exhibit 3.7 Selected Studies and Key Findings of PSC-Based Therapies in Development for AMD, Diabetes, Liver Disease, Parkinson’s and Thalassemia
- Exhibit 3.8 Ocata Therapeutics Current Stem Cell Trials, Globally
- Exhibit 3.9 CHA Biotech Current Stem Cell Trials, Globally
- Exhibit 3.10 Pfizer Current Stem Cell Trials, Globally
- Exhibit 3.11 GSK Current Stem Cell Trials, Globally
- Exhibit 3.12 Bayer Current Stem Cell Trials, Globally
- Exhbit 3.13 Mesoblast International Current Stem Cell Trials, Globally
- Exhibit 3.14 Millennium Pharmaceutical Current Stem Cell Trials, Globally
- Exhibit 3.15 AstraZeneca Current Stem Cell Trials, Globally
- Exhibit 3.16 Merck Current Stem Cell Trials, Globally
- Exhibit 3.17 Chimerix Current Stem Cell Trials, Globally
- Exhibit 3.18 Eisai Current Stem Cell Trials, Globally
- Exhibit 3.19 SanBio Current Stem Cell Trials, Globally
- Exhibit 3.20 Celgene Current Stem Cell Trials, Globally
- Exhibit 3.21 StemCells Current Stem Cell Trials, Globally
- Exhibit 3.22 Genzyme (Sanofi) Current Stem Cell Trials, Globally
- Exhibit 3.23 Teva Current Stem Cell Trials, Globally
- Exhibit 3.24 MedImmune Current Stem Cell Trials, Globally
- Exhibit 3.25 Janssen Current Stem Cell Trials, Globally
- Exhibit 3.26 Seattle Genetics Current Stem Cell Trials, Globally
- Exhibit 3.27 Baxter Healthcare Current Stem Cell Trials, Globally
- Exhibit 3.28 InCyte Corp Current Stem Cell Trials, Globally
- Exhibit 4.1 Disease Models Generated from iSPC using Genome Editing
- Exhibit 4.2 Stem Cells Used for Drug Screening
- Exhibit 4.3 Sucessful Human iPSC Mediate Therapy Cases
- Exhibit 4.4 Number of US Patients That Could Benefit From Stem Cell Therapeutics
- Exhibit 4.5 Genentechs Stem Cell Platform for Drug & Toxicity Screening
- Exhibit 4.6 Key Challenges in Assessing Genetic Instability of Stem Cells
- Exhibit 4.7 Comprehensive In Vitro Proarrhythmia Assay (CiPA) Components
- Exhibit 4.8 Ex Vivo Gene Therapy and Stem Cell Technology
- Exhibit 4.9 Genome Editing and iPSCs
- Exhibit 4.10 Gene Edited iPSC/hES-Mediated Novel Therapy Development
- Exhibit 4.11 Comparison of 3D and 2D Cultures of iPSC-Derived Hepatocytes Following Treatment with Toxins, Anti-Proliferative Agents and Other Drugs
- Exhibit 4.12 Potential Applications of Human iPSCs for Liver Diseases
- Exhibit 4.13 Myocardial Tissue: Cardiomyocytes, Endothelial Cells and Fibroblasts
- Exhibit 4.14 Cardiovascular Disease-Specific Human Pluripotent Stem Cell Lines by Genetic Cause and Drug Testing
- Exhibit 4.15 Culture of Human iPSC-Derived Dopaminergic Neurons over 14 Days
- Exhibit 4.16 Strategies for Generating Disease Models Using Human Pluripotent Stem Cells (PSCs)
- Exhibit 4.17 Criteria for Disease Modelling Using Pluripotent Stem Cells
- Exhibit 4.18 Models of Monogenic Dominant Diseases
- Exhibit 4.19 Models of Monogenic Recessive Diseases
- Exhibit 4.20 Models of Monogenic X-linked Recessive Diseases
- Exhibit 4.21 iPSCs in Neurological Disease Modeling, Drug Screening & Cell Therapy
- Exhibit 4.22 Advantages and Uses of Intestinal Organoids
- Exhibit 5.1: Main Biomarkers Associated with Pluripotent Stem Cells
- Exhibit 5.2: Pluripotent Stem Cell Biomarkers
- Exhibit 5.3 Main Biomarkers Associated with Mesenchymal Stem Cells
- Exhibit 5.4 Mesenchymal Stem Cell Biomarkers
- Exhibit 5.5 Main Biomarkers Associated with Neural Stem Cells
- Exhibit 5.6 Neural Stem Cell Biomarkers
- Exhibit 5.7 Main Biomarkers Associated with Hematopoietic Stem Cells
- Exhibit 5.8 Hematopoietic Stem Cell Biomarkers
- Exhibit 6.1 Bioprocess Development Considerations for hPSC-Derived Products
- Exhibit 6.2 Technologies Used for Expansion & Differentiation of hPSC-Derived Cell Products
- Exhibit 6.3 Comparison of Key Performance Characteristics of Cardiomyocytes, Hepatocytes, Neurons, Neural Progenitor Cells, Endoderm Progenitors and Hepatocytes in Planar & Bioreactor Based Differentiation Protocols
- Exhibit 6.4 Integrated Expansion & Differentiation of hPSCs Studies by Cell, Process, Cell Density, Process Time and Target Cells Produced
- Exhibit 6.5 hPSC Bioprocess Strategies, Planar, Segregated 3D & Integrated: Advantages & Disadvantages
- Exhibit 6.6 Main Objectives of GMP Manufacturing
- Exhibit 6.7 GMP Facilities Required for Stem Cell Product Manufacuring
- Exhibit 6.8 Manufacturing Overview of hIPSCs under GMP Regulation
- Exhibit 6.9 Key Steps in Manufacturing GMP Regulated iPSCs
- Exhibit 6.10 Characterization and Release Assays for Human iPSCs Manufactured under GMP Conditions
- Exhibit 6.11 MCB Viral Assays for use on Human iPSCs Bank
- Exhibit 6.12 Differences Between Autologous & Allogeneic Cell Therapy Models
- Exhibit 7.1 Selected Venrock Biotech and Healthcare Exits
- Exhibit 7.2 Stem Cell Funding Bodies, Globally
- Exhibit 7.3 Stem Cell Societies and Consortiums by Geography
- Exhibit 7.4 Total Stem Cell NIH Funding 2014-2017
- Exhibit 7.5 NIH Funded Stem Cell Related Projects 2014-2017
- Exhibit 7.6 Tabular Data NIH Funded Stem Cell Related Projects 2014-2017
- Exhibit 7.7 CIRM Investment Funding by Stem Cell Type
- Exhibit 7.8 CIRM Stem Cell Project Investment Funding by Therapeutic Area
- Exhibit 7.9 Promising Cell & Gene Companies
- Exhibit 8.1 Global Frequency Indicator Trend of Terms Regenerative Medicine, Cell Therapy and Tissue Engineering, 2007-2017
- Exhibit 8.2 GeoMap Frequency Indicator Trend of Terms Regenerative Medicine, Cell Therapy and Tissue Engineering, 2007-2017
- Exhibit 8.3 Increased Proportion of People Over 65 Through 2050
- Exhibit 8.4 Percentage of Global Population Aged 65 Plus 2015-2050
- Exhibit 8.5 Global Alzheimer’s Disease Market Forecast
- Exhibit 8.6 Global Cardiovascular Market Forecast
- Exhibit 8.7 Global Diabetes Therapy and Device Market Forecast
- Exhibit 8.8 Bone Graft Global Market Forecast
- Exhibit 8.9 Bone Graft Global Market Forecast by Geography
- Exhibit 8.10 Total Global Financings of the Regenerative Medicine, Cell and Gene Therapy and Tissue Engineering Sector
- Exhibit 8.11 Total Global Financing of Regenerative Medicine & Cellular/Gene Therapy by Type
- Exhibit 8.12 Number of Global Clinical Trials by Phase of Regenerative Medicine, Cell and Gene Therapy Studies
- Exhibit 8.13 Number of Global Clinical Trials by Indication of Regenerative Medicine, Cellular & Gene Therapeutics
- Exhibit 8.14 Major Clinical Trial Events in Regenerative Medicine
- Exhibit 8.15 Global Regenerative Medicine Market Value Tabular Forecast to 2025
- Exhibit 8.16 Global Regenerative Medicine Market Value Forecast to 2025
- Exhibit 8.17 Regenerative Medicine Geographic Analysis and Forecast to 2025
- Exhibit 8.18 Regenerative Medicine Geographic Forecast Table to 2025
- Exhibit 8.19 Regenerative Medicine Market Share by Geography 2019
- Exhibit 8.20 Regenerative Medicine Market Share Forecast by Geography 2025
- Exhibit 8.21 North America Regenerative Medicine Forecast to 2025
- Exhibit 8.22 European Regenerative Medicine Forecast to 2025
- Exhibit 8.23 Asia Pacific Regenerative Medicine Forecast to 2025
- Exhibit 8.24 RoW Regenerative Medicine Forecast to 2025
- Exhibit 8.25 Geographical Location of Regenerative Medicine Companies
- Exhibit 8.26 Regenerative Medicine Technology Breakdown of Companies
- Exhibit 8.27 Number and Geographical Location of Regenerative Medicine, Cellular Therapy & Gene Therapy Companies, Globally
- Exhibit 8.28 Select FDA-Approved Regenerative Medicine Products by Biologics. Cell Based and Biopharmaceuticals
- Exhibit 8.29 Regulatory Approved & Commercialized Regenerative Medicine Products Currently on the Market
- Exhibit 8.30 Major Regenerative Medicine Milestones
- Exhibit 9.1 Global Stem Cell Therapy Market Forecast Table to 2025
- Exhibit 9.2 Global Stem Cell Therapy Market Forecast to 2025
- Exhibit 9.3 Stem Cell Market Share by Adult and Embryonic Stem Cells and Stem Cell Banking
- Exhibit 9.4 Major Clinical Trial Events in Stem Cell Medicine
- Exhibit 9.5 Stem Cell Geographic Market Share Forecast to 2025
- Exhibit 9.6 Global Stem Cell Market Share by Geographic Region 2019
- Exhibit 9.7 Global Stem Cell Market Share by Geographic Region 2025
- Exhibit 9.8 North American Stem Cell Market Forecast to 2025
- Exhibit 9.9 Asia Pacific Stem Cell Market Forecast to 2025
- Exhibit 9.10 European Stem Cell Market Forecast to 2025
- Exhibit 9.11 Rest of the World Stem Cell Market Forecast to 2025
- Exhibit 9.12 Market Share of Top Therapeutic Indications in Stem Cell Space, 2019
- Exhibit 9.13 Market Share of Top Therapeutic Indications in Stem Cell Space, 2025
- Exhibit 9.14 Stem Cell Market Forecast by Therapeutic Indications to 2025
- Exhibit 9.15 Orthopedic/Musculoskeletal Stem Cell SubMarket Forecast to 2025
- Exhibit 9.16 Cancer Stem Cell SubMarket Forecast to 2025
- Exhibit 9.17 Cardiology/Vascular Stem Cell SubMarket Forecast to 2025
- Exhibit 9.18 Wound Healing Stem Cell SubMarket Forecast to 2025
- Exhibit 9.19 Skin Stem Cell Products and Sources
- Exhibit 9.20 Skin Stem Cell SubMarket Forecast to 2025
- Exhibit 9.21 Ocular Stem Cell SubMarket Forecast to 2025
- Exhibit 9.22 Current Top Brands Being Used for Stem Cell R&D
- Exhibit 9.23 Most Frequent Method of Obtaining Stem Cell Lines in R&D
- Exhibit 9.24 Percentage of Stem Cell Characterization Analysis Kits Used in R&D
- Exhibit 9.25 Percentage of Stem Cell Differentiation Kits Used in R&D
- Exhibit 9.26 Most Common Types of Stem Cells Used in R&D by Mouse, Human & Rat Origin
- Exhibit 10.1 Global Tissue Engineering Market Tabular Forecast to 2025
- Exhibit 10.2 Global Tissue Engineering Market Forecast to 2025
- Exhibit 10.3 Global Tissue Engineering Market Forecast by Geographic Region to 2025
- Exhibit 10.4 North America Tissue Engineering Market Forecast to 2025
- Exhibit 10.5 Europe Tissue Engineering Market Forecast to 2025
- Exhibit 10.6 Asia Pacific Tissue Engineering Market Forecast to 2025
- Exhibit 10.7 Geographical Breakdown of Tissue Engineering Companies Globally
- Exhibit 10.8 Public and Privately Held Tissue Engineering Company Distribution, Globally
- Exhibit 10.9 Main Players in the Tissue Engineering Market
- Exhibit 10.10 Main Players in the CAR-T Market
- Exhibit 10.11 Main Players in the TCR Market
- Exhibit 10.12 Main Players in the NK Cell Market
- Exhibit 10.13 Main Players in the TILs Market
- Exhibit 10.14 Global Tissue Engineering Submarket Breakdown by Market Share 2019
- Exhibit 10.15 Global Tissue Engineering Submarket Breakdown by Market Share Forecast 2025
- Exhibit 10.16 Tissue Engineering Submarket Breakdown Forecast Table to 2025
- Exhibit 10.17 Tissue Engineering Submarket Breakdown Forecast to 2025
- Exhibit 10.18 Orthopedics/Musculoskeletal Tissue Engineering Market Forecast to 2025
- Exhibit 10.19 Oncology Tissue Engineering Market Forecast to 2025
- Exhibit 10.20 Cardiology and Vascular Tissue Engineering Market Forecast to 2025
- Exhibit 10.21 Dermatology Tissue Engineering Market Forecast to 2025
- Exhibit 10.22 Oral and Dental Tissue Engineering Market Forecast to 2025
- Exhibit 11.1 Number of Stem Cell Donors by Geographical Location
- Exhibit 11.2 Number and Geographical Location of Global Unrelated Cord Blood Units
- Exhibit 11.3 Market Share of Companies in the BioBanking Industry
- Exhibit 11.4 Market Share within Therapeutic Companies in the BioBanking Industry
- Exhibit 11.5 Market Share within Cell & Tissue Banks in the BioBanking Industry
- Exhibit 11.6 Percentage of Allogenic & Autologous Transplantations
- Exhibit 11.7 Percentage Breakdown of Indications using Autologous Umbilical Cord Blood Transplants
- Exhibit 11.8 Percentage Breakdown of Indications using Allogenic Umbilical Cord Blood Transplants
- Exhibit 11.9 Global Cord Blood Banking Market Forecast to 2025
- Exhibit 11.10 Stem Cell Biobanking Market Segments
- Exhibit 11.11 Top Global Cord Blood and Tissue Companies
- Exhibit 11.12 Important Players in the International Private Cord Bank Market
- Exhibit 12.1 Key Challenges to the Regenerative Medicine & Cellular/Gene Therapy Market
- Exhibit 12.2 Company and Indication that will Benefit from New 21st Century Cures Act, USA
- Exhibit 12.3 Cell and Gene Based Therapy in Japan as Defined by the PMDA
- Exhibit 12.4 Regulatory System in Japan for Regenerative Medicine and Cell and Gene Therapy Products
- Exhibit 12.5 Main Stem Cell Research Institutes in China
- Exhibit 13.1 Selected CD19-directed Product Candidates in Clinical Trials by Costimulatory & Binding Domains, Starting Cell Population, Vector and Ablation Technology
- Exhibit 13.2 Select CD19-Directed ALL Clinical Trials
- Exhibit 13.3 Select Anti-CD22 CAR-T Clinical Projects
- Exhibit 13.4 CBER Compliance and Surveillance Activities
- Exhibit 13.5 Contacts for the Cellular, Tissue and Gene Therapies Advisory Committee, FDA
- Exhibit 13.6 Clinical Regulatory Pathway – Conventional Route
- Exhibit 13.7 Clinical Regulatory Pathway – Option for Rapid Translation
- Exhibit 13.8 PMDA Total Review Period of Standard Drugs
- Exhibit 13.9 PMDA Total Review Period of Priority Drugs
- Exhibit 13.10 Number of Approved Recombinant Protein Products by PMDA
- Exhibit 13.11 Forerunner Review Assignment System Timeframe
- Exhibit 13.12 Adaptive Licensing and Accelerated Approval in Japan‐US‐EU
- Exhibit 13.13 Key Contacts Within PMDA, Japan
- Exhibit 13.14 CheckMate 066 Clinical Trial
- Exhibit 13.15 CheckMate 037 Clinical Trial
- Exhibit 13.16 Contact Details for EMA Cell Therapy & Immunotherapy Experts
- Exhibit 13.17 Method of Generating CAR-Modified T Cells
- Exhibit 13.18 Clinical Activity, Cost Structure and Patient Convenience Flow Chart of CAR-T Therapy
- Exhibit 13.19 General Technical and Personnel Requirements of a GMP, QC, QA, FDA Regulated Cell Therapy Manufacturing Facility
- Exhibit 13.20 Technician/Scientific Requirements for CAR T Manufacturing
- Exhibit 13.21 Selection of Apheresis Instruments Currently on the Market
- Exhibit 13.22 Selection of Cell Counters and Analyzer Instruments Currently on the Market
- Exhibit 13.23 Main Objectives of GMP Manufacturing Immunotherapeutics
- Exhibit 13.24 Main Objectives of Quality Control While Manufacturing Immunotherapeutics
- Exhibit 13.25 Main Objectives of Regulatory Affairs During Manufacturing Immunotherapeutics
- Exhibit 13.26 CAR-T Studies Using mRNA Transfection Electroporation
- Exhibit 13.27 Allogenic Versus Autologous Cell Manufacturing
- Exhibit 13.28 Challenges for Autologous Cell Therapy Manufacture
- Exhibit 13.29 Current Company/Institutions with Suicide Gene CAR T Projects
- Exhibit 13.30 Advantages of Using Automated Cell Therapy Manufacturing
- Exhibit 13.31 Main Drivers to Implement Automated Cell Therapy Manufacturing
- Exhibit 13.32 Main Benefits of Automated Cell Therapy Manufacturing
- Exhibit 13.33 Advantages & Disadvantages of Autologous Cell Therapy Manufacture Scale Up
- Exhibit 13.34 Streptamer® -Based Magnetic Bead Cell Isolation Exhibit 13.35 Juno Therapeutics Manufacturing Facility Objectives
- Exhibit 13.36 Annual Cost of Patented Cancer Therapeutics from 2000 to Today
- Exhibit 13.37 Cost of Nivolumab, Pembrolizumab & Ipilimumab per mg
- Exhibit 13.38 Current Juno Therapeutics Trials and CAR T Products
- Exhibit 13.39 Current CAR T Business Deals
- Exhibit 13.40 Selected Antigens, Endomains and Gene Transfer Methods Used for CAR-T Therapy
- Exhibit 13.41 Immunosuppressive Modulators in Tumor Microenvironment
- Exhibit 13.42 Challenges for CAR-T therapy and Solid Tumors
- Exhibit 13.43 Tumor Associated Antigens for CART Therapy by Tissue Type
- Exhibit 13.44 Select Clinical Trials using CAR-T in Solid Tumors
- Exhibit 14.1 MultiStem Platform in Action
- Exhibit 14.2 Key Advantages of MultiStem
- Exhibit 14.3 Athersys Product and Clinical Pipeline
- Exhibit 14.4 Athersys Key Business Strategies
- Exhibit 14.5 Baxter International Product Revenue by Class
- Exhibit 14.6 Baxter International Product Revenue by Geography
- Exhibit 14.7 Baxter International Breakdown of Product Revenue
- Exhibit 14.8 Caladrius Expertise in Cell Type and Therapeutic Application Portfolio
- Exhibit 14.9 PCT Caladrius CLBS03 Treg Cellular Therapy Manufacturing Process
- Exhibit 14.10 Caladrius Revenue
- Exhibit 14.11 Caladrius Clinical Manufacturing Revenue
- Exhibit 14.12 Caladrius Process Development Revenue
- Exhibit 14.13 Cytori Cell Therapy Mechanism of Action in Angiogenesis, Inflammation and Wound Remodeling
- Exhibit 14.14 Cytori Therapeutics Cell Therapy Clinical Pipeline
- Exhibit 14.15 MediPost Product Pipeline by Indication and Clinical Study Phase
- Exhibit 14.16 Medipost Sales Figures
- Exhibit 14.17 CellTree Umbilical Cord Blood Bank Program Details and Pricing
- Exhibit 14.18 Medipost Revenue Share by Product Category
- Exhibit 14.19 Medipost Sales Revenue by Product Category
- Exhibit 14.20 Medipost Umbilical Cord Blood Bank Revenue
- Exhibit 14.21 Medipost Stem Cell Drug Sales Revenue
- Exhibit 14.22 Medipost R&D Investment
- Exhibit 14.23 Mesenchymal Lineage Adult Stem Cells (MLCs) Secrete a Variety of Immunomodulatory Molecules
- Exhibit 14.24 Mesoblast Mesenchymal Lineage Adult Stem Cell (MLC) Functional Properties
- Exhibit 14.25 Mesoblast Expanion and Immune Privilege of MLC Technology
- Exhibit 14.26 Mesoblast Complementary Technology Platforms
- Exhibit 14.27 Mechanism of Action of MPC-150-IM, MPC-06-ID, MPC-300-IV, TEMCELL(R)HS. Inj. and MSC-100-IV and MPC-25-OSTEO
- Exhibit 14.28 Mesoblast MLC-Based Product Manufacturing and Distribution Process
- Exhibit 14.29 Mesoblast Patent Portfolio with Expiration and Validity through 2035
- Exhibit 14.30 Mesoblast Tier 1 and Tier 2 Product Candidates by Program and Clinical Stage
- Exhibit 14.31 Mesoblast Lead Product MSC-100-IV/TEMCELL HS Inj
- Exhibit 14.32 MSC-100-IV Treatment in Children with SR-aGVHD who Failed Other Modalities
- Exhibit 14.33 MPC-300-IV for Treatment of Chronic Inflammatory Diseases
- Exhibit 14.34 Mesoblast International Strategic Business Collaborations
- Exhibit 14.35 Mesoblast Share Price and Financial Analysis
- Exhibit 14.36 Mesoblast Revenue Generated
- Exhibit 14.37 Mesoblast R&D Expenditure
- Exhibit 14.38 NuVasive Biologics Portfolio
- Exhibit 14.39 NuVasive Global Revenue
- Exhibit 14.40 NuVasive NON GAAP Operating Profit Margin
- Exhibit 14.41 NuVasive Spinal Surgery Product and Biologic Revenue Breakdown
- Exhibit 14.42 NuVasive USA and International Revenue Breakdown
- Exhibit 14.43 NuVasive Corporate Strategy Going Forward
- Exhibit 14.44 Osiris Therapeutics Current Product Portfolio
- Exhibit 14.45 Osiris Therapeutics Product Pipeline by Indication, Preclinical, Clinical and Market Stage
- Exhibit 14.46 Exhibit Plasticel Partnerships and Collaborations with Industry and Academic Institutions
- Exhibit 14.47 Pluristem Therapeutics Company Pipeline Portfolio by Product, Indication, Location & Phase
- Exhibit 14.48 Pluristem Therapeutics Production of PLX-PAD & PLX-R18
- Exhibit 14.49 Pluristem Therapeutics Revenue
- Exhibit 14.50 Pluristem Therapeutics R&D Costs
- Exhibit 14.51 Pfizer Stem Cell Policy
- Exhibit 14.52 StemCell Inc Manufacturing Steps of Hu-CNS-SC Product
- Exhibit 14.53 STEMCELL Technologies Product Portfolio
- Exhibit 14.54 STEMCELL Technologies Brand Portfolio
- Exhibit 14.55 Takara Bio Sales Revenue
- Exhibit 14.56 Takara Bio Operating Sales
- Exhibit 14.57 Takara BioIndustry Sales Revenue
- Exhibit 14.58 Takara Bio Sales by Geographic Region
- Exhibit 14.59 Tigenix Key Intellectual Property Patent Portfolio
- Exhibit 14.60 Comprehensive List of Companies in the Stem Cell & Regenerative Medicine Industry
- Exhibit 15.1 Advantages, Weaknesses, Opportunities & Threats of Allogenic & Autologous Stem Cells
- Exhibit 15.2 Opportunistic Therapeutic Indications as Decided by Senior Key Opinion Leaders
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