The Market for Library Preparation and Target Enrichment for Next-Generation Sequencing (NGS) 2021

The Market for Library Preparation and Target Enrichment for Next-Generation Sequencing (NGS) 2021

This report, Market for Library Preparation and Target Enrichment for Next-Generation Sequencing (NGS), examines the current market, providing a comprehensive market summary, including NGS sample preparation revenues and growth rates for 2021-2026 and NGS sample preparation revenues by geographic region for 2020 (North America, Europe, Asia-Pacific, rest-of-world).

The introduction of smaller, cheaper benchtop NGS systems has expanded the market into smaller labs that could never afford prices for earlier systems. Due to their lower throughput, they are suitable for a variety of applications but not for most whole genome sequencing. With the high performance provided by these smaller systems, the sales do not appear to be slowing down and the trend is expected to continue as the price of benchtop instruments is still being dropped. These systems are largely being used for amplicon sequencing and targeted sequencing, as well as RNA or small/ micro RNA sequencing. But this rapid rate of adoption of the benchtop systems has fueled the growth for reagents and kits for these various applications. In particular, there has been a great demand for panels of genes related to specific disease areas.

Library Preparation and Target Enrichment is thus a crucial part of sequencing, and one where there are many more competitors than in the market for the instrument systems themselves. The report covers the market for Library Preparation and Target Enrichment. It lists products from over 220 companies and profiles the major players in the space among them.

As NGS science continues to evolve, the report examines trends in the market, including:

  • Acceptance and Validation of Clinical Applications
  • Geographies and Market Size and Growth Within Geographies
  • Broad Range of Deals and Acquisitions that Have Occurred
  • COVID-19 Impact on the Market and Expectations for 2021
  • Litigation and IP Status
Further, the report covers information about many of the current products available in the market, including the hardware, reagents, kits, and other consumables.

The Market for Library Preparation a nd Target Enrichment for Next-Generation Sequencing presents the following market data:
  • Library Preparation and Target Enrichment Market Size
  • Library Preparation and Target Enrichment, Growth to 2026
  • Library Preparation and Target Enrichment, Products on the Market
  • Market shares of companies in Library Preparation and Target Enrichment Market
  • Geographic Breakout of the Library Preparation and Target Enrichment Market
  • Strategic Recommendations
  • 220+ Products on the Market
  • Partnerships and Deals among LP/TE Players
  • Company Profiles
Agilent, Illumina, Qiagen, Roche and Thermo Fisher Scientific are among the market leaders profiled in the report

The report contains discussion of key challenges in the market for library preparation and target enrichment products, and provides strategic recommendations moving forward.


  • Executive Summary
    • Introduction
      • Product Introductions, Indications of Price Pressure
      • Stability in Sequencers Appears to Be Continuing
      • A Period of Rapid Adoption, But Lower Prices
      • High Likelihood of Longer-Term Challenges
    • Size and Growth of the Market
      • Background
    • Scope and Methodology
      • Applications and Definitions
  • Trends
    • Falling Costs, Improved Output, Smaller and Simpler
      • Broad Range of Deals and Acquisitions
      • New Technologies Continuing to Push Boundaries
      • China Becoming Major Player in Market
      • More Systems Stalled or Cancelled
      • Gradual Acceptance and Validation of Clinical Applications
      • Settlement or Resolution of Litigation
      • Success in Microbiology and Pathogen Detection
      • Regulatory Trends
  • Products
    • Table Selected Library Prep and Target Enrichment Products / Technologies Offered
  • Revenues
    • Revenues Forecast
      • Table Cost of Sequencing a Genome
      • Table NGS Library Prep. & Target Enrichment Est. Revenues, 2021-2026 ($M)
      • Table NGS Library Prep. & Target Enrichment Growth Rate, 2021-2026
      • Table NGS Library Prep. & Target Enrichment Est. Revenues, 2021-2026 ($M)
      • Table NGS Library Prep. & Target Enrichment Growth Rate, 2022-2026
      • Revenues by Region
        • Table NGS Sample Preparation Est. Revenues by Region, 2021 (N. America, Europe, Asia-Pacific, Rest-of-World) ($M)
        • Table NGS Sample Preparation Est. Revenues by Region, 2021 (N. America, Europe, Asia-Pacific, Rest-of-World) (%)
      • Illumina Sequencing Consumables Revenues
        • Table Illumina Quarterly Sequencing Consumables Revenues (2014- Q1 2021) ($M)
        • Table Illumina Quarterly Sequencing Consumables Revenues (2014- Q1 2021) ($M)
        • Table Illumina Consumables Share of Revenues (2016-2020) ($M)
        • Table Illumina 2016 Sequencing Consumables Share (%)
        • Table Illumina 2020 Sequencing Consumables Share (%)
        • Table Illumina Sequencing Consumables Growth Rates, 2016-2020 (%)
  • Competitive
    • Introduction
      • Continued Growth and Technology Advances
      • Sequencer Battles Turn Somewhat Calm
      • Library Preparation and Target Enrichment Market Shares
        • Table Library Preparation and Target Enrichment Est. Market Shares by Company, 2021 ($M, %)
        • Table Library Preparation and Target Enrichment Est. Market Shares by Company, 2021 (%)
      • Smaller Companies Experiencing Mixed Success
  • Deals
    • Table Recent Selected Significant Deals in the NGS Library Preparation and Target Enrichment Market
  • Corporate Profiles
    • 10X Genomics
    • Agilent Technologies
    • Fluidigm
    • Illumina
    • Oxford Nanopore
    • Pacific Biosciences
    • Qiagen
    • Roche
    • Thermo Fisher Scientific
  • Challenges
    • Highly Concentrated Sequencer Market Increases Risks
      • Challenges Arising with Clinical Trials
      • Dropping Sequencing Costs Create Complex Situations
      • Potential for Disruptive Technology or Litigation
      • Diagnoses, Treatments, Ethics Still Inexact
      • Unknown Effects of Closed Systems, Automation, Streamlining
      • Some Advances Can Reduce Markets
      • Sample Preparation Customer Loyalty Lacking
      • Shortcomings and Pitfalls Require Solutions
      • Low Barriers Can Increase Competition Short-Term
      • Cautious Approach with LDT Regulation
      • Complexity and Difficulty Restrains Broad Adoption
      • Many Labs Opting for Services over Purchasing Sequencers
    • Strategic Recommendations
      • Diversify Products and Applications
      • Expanding Market Requires Technical Support
      • Reduce Bias, Compensate, or Characterize It
      • Capitalize on Stability While Preparing for Contingencies
      • Address or Anticipate Price Pressure
      • Benefit from Partnering or Communicating
      • Use Services for Visibility and Monetization
      • Address or Ease Data Analysis Challenges
      • Anticipate or Position for Global Adoption

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