Esophageal Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

Esophageal Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034


The 7 major esophageal cancer markets reached a value of US$ 9.0 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 16.5 Billion by 2034, exhibiting a growth rate (CAGR) of 5.71% during 2024-2034.

The esophageal cancer market has been comprehensively analyzed in IMARC's new report titled "Esophageal Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Esophageal cancer refers to a type of cancer that develops in the cells of the esophagus, the muscular tube that carries liquid and food from the throat to the stomach. There are mainly two types of esophageal cancer: squamous cell carcinoma and adenocarcinoma. The former originates in the flat cells that line the esophagus, while the latter develops in the glandular cells that produce mucus in the lower portion of the esophagus. The most common symptom of the disorder is difficulty in swallowing, which can progress to a sensation of food being stuck in the throat. Other symptoms include pain or discomfort in the chest or back, unintentional weight loss, persistent coughing or hoarseness, heartburn or acid reflux, vomiting, regurgitation of food or liquid, chronic hiccups, etc. The diagnosis of esophageal cancer typically involves a combination of several tests and procedures. Various imaging tests, such as a barium swallow, CT scan, PET scan, etc., are used to visualize the esophagus and look for signs of cancerous cells. A biopsy, in which a small tissue sample is removed from the esophagus and examined under a microscope, is usually needed to confirm the diagnosis. Additionally, an endoscopy or laparoscopy may also be performed, depending on the location and size of the tumor, to help guide the biopsy or obtain additional tissue samples.

The increasing cases of chronic inflammation of the esophagus, which can result from gastroesophageal reflux disease (GERD), are primarily driving the esophageal cancer market. Furthermore, the rising prevalence of several associated risk factors, such as tobacco use, heavy alcohol consumption, obesity, certain medical conditions like achalasia, etc., is also propelling the market. In addition to this, the inflating utilization of endoscopic imaging techniques, including narrow-band imaging (NBI) and confocal laser endomicroscopy (CLE), for diagnosing esophageal cancer is creating a positive outlook for the market. These approaches use high-resolution images to detect abnormalities in the esophageal lining and can help in guiding biopsy sampling. Moreover, the widespread adoption of neoadjuvant therapy on account of its numerous benefits, such as the increased chance of complete tumor removal and decreased risk of disease recurrence, is further bolstering the market growth. Apart from this, the emerging popularity of multimodal approaches, which involve combining different treatment modalities, including chemotherapy, radiation therapy, surgery, etc., to improve outcomes for patients with esophageal cancer, is acting as another significant growth-inducing factor. Additionally, the rising adoption of immunotherapy, which involves using the body's immune system to fight cancer, for treating certain cases of esophageal cancer caused by specific genetic mutations, is also augmenting the market growth. Besides this, the escalating usage of minimally invasive surgeries, such as endoscopic resection, since they can reduce the risk of complications and speed up recovery time compared to traditional open procedures, is expected to drive the esophageal cancer market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the esophageal cancer market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for esophageal cancer and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the esophageal cancer market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the esophageal cancer market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the esophageal cancer market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current esophageal cancer marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the esophageal cancer market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the esophageal cancer market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the esophageal cancer market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of esophageal cancer across the seven major markets?
What is the number of prevalent cases (2018-2034) of esophageal cancer by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of esophageal cancer by gender across the seven major markets?
What is the number of prevalent cases (2018-2034) of esophageal cancer by type across the seven major markets?
How many patients are diagnosed (2018-2034) with esophageal cancer across the seven major markets?
What is the size of the esophageal cancer patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of esophageal cancer?
What will be the growth rate of patients across the seven major markets?

Esophageal Cancer: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for esophageal cancer drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the esophageal cancer market?
What are the key regulatory events related to the esophageal cancer market?
What is the structure of clinical trial landscape by status related to the esophageal cancer market?
What is the structure of clinical trial landscape by phase related to the esophageal cancer market?
What is the structure of clinical trial landscape by route of administration related to the esophageal cancer market?


1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Esophageal Cancer - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Esophageal Cancer - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Esophageal Cancer - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (​2018-2023​)
7.2.2 Epidemiology Forecast (​2024-2034​)
7.2.3 Epidemiology by Age (​2018-2034​)
7.2.4 Epidemiology by Gender (​2018-2034​)
7.2.5 Epidemiology by Type (​2018-2034​)
7.2.6 Diagnosed Cases (​2018-2034​)
7.2.7 Patient Pool/Treated Cases (​2018-2034​)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (​2018-2023​)
7.3.2 Epidemiology Forecast (​2024-2034​)
7.3.3 Epidemiology by Age (​2018-2034​)
7.3.4 Epidemiology by Gender (​2018-2034​)
7.3.5 Epidemiology by Type (​2018-2034​)
7.3.6 Diagnosed Cases (​2018-2034​)
7.3.7 Patient Pool/Treated Cases (​2018-2034​)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (​2018-2023​)
7.4.2 Epidemiology Forecast (​2024-2034​)
7.4.3 Epidemiology by Age (​2018-2034​)
7.4.4 Epidemiology by Gender (​2018-2034​)
7.4.5 Epidemiology by Type (​2018-2034​)
7.4.6 Diagnosed Cases (​2018-2034​)
7.4.7 Patient Pool/Treated Cases (​2018-2034​)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (​2018-2023​)
7.5.2 Epidemiology Forecast (​2024-2034​)
7.5.3 Epidemiology by Age (​2018-2034​)
7.5.4 Epidemiology by Gender (​2018-2034​)
7.5.5 Epidemiology by Type (​2018-2034​)
7.5.6 Diagnosed Cases (​2018-2034​)
7.5.7 Patient Pool/Treated Cases (​2018-2034​)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (​2018-2023​)
7.6.2 Epidemiology Forecast (​2024-2034​)
7.6.3 Epidemiology by Age (​2018-2034​)
7.6.4 Epidemiology by Gender (​2018-2034​)
7.6.5 Epidemiology by Type (​2018-2034​)
7.6.6 Diagnosed Cases (​2018-2034​)
7.6.7 Patient Pool/Treated Cases (​2018-2034​)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (​2018-2023​)
7.7.2 Epidemiology Forecast (​2024-2034​)
7.7.3 Epidemiology by Age (​2018-2034​)
7.7.4 Epidemiology by Gender (​2018-2034​)
7.7.5 Epidemiology by Type (​2018-2034​)
7.7.6 Diagnosed Cases (​2018-2034​)
7.7.7 Patient Pool/Treated Cases (​2018-2034​)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (​2018-2023​)
7.8.2 Epidemiology Forecast (​2024-2034​)
7.8.3 Epidemiology by Age (​2018-2034​)
7.8.4 Epidemiology by Gender (​2018-2034​)
7.8.5 Epidemiology by Type (​2018-2034​)
7.8.6 Diagnosed Cases (​2018-2034​)
7.8.7 Patient Pool/Treated Cases (​2018-2034​)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (​2018-2023​)
7.9.2 Epidemiology Forecast (​2024-2034​)
7.9.3 Epidemiology by Age (​2018-2034​)
7.9.4 Epidemiology by Gender (​2018-2034​)
7.9.5 Epidemiology by Type (​2018-2034​)
7.9.6 Diagnosed Cases (​2018-2034​)
7.9.7 Patient Pool/Treated Cases (​2018-2034​)
8 Esophageal Cancer - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Esophageal Cancer - Unmet Needs
10 Esophageal Cancer - Key Endpoints of Treatment
11 Esophageal Cancer - Marketed Products
11.1 List of Esophageal Cancer Marketed Drugs Across the Top 7 Markets
11.1.1 Keytruda (Pembrolizumab) - Merck & Co
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Opdivo (Nivolumab) - Bristol-Myers Squibb/Ono Pharmaceuticals
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Photofrin (Porfimer sodium) - Pinnacle Biologics
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 Esophageal Cancer - Pipeline Drugs
12.1 List of Esophageal Cancer Pipeline Drugs Across the Top 7 Markets
12.1.1 Tiragolumab - Genentech
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Atezolizumab - Genentech
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Zanidatamab - Zymeworks
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 Ramucirumab - Eli Lilly and Company
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 Tislelizumab - BeiGene
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. Esophageal Cancer - Attribute Analysis of Key Marketed and Pipeline Drugs
14. Esophageal Cancer – Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Esophageal Cancer - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Esophageal Cancer - Market Size
15.2.1.1 Market Size (​2018-2023​)
15.2.1.2 Market Forecast (​2024-2034​)
15.2.2 Esophageal Cancer - Market Size by Therapies
15.2.2.1 Market Size by Therapies (​2018-2023​)
15.2.2.2 Market Forecast by Therapies (​2024-2034​)
15.3 Market Scenario - United States
15.3.1 Esophageal Cancer - Market Size
15.3.1.1 Market Size (​2018-2023​)
15.3.1.2 Market Forecast (​2024-2034​)
15.3.2 Esophageal Cancer - Market Size by Therapies
15.3.2.1 Market Size by Therapies (​2018-2023​)
15.3.2.2 Market Forecast by Therapies (​2024-2034​)
15.3.3 Esophageal Cancer - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Esophageal Cancer - Market Size
15.4.1.1 Market Size (​2018-2023​)
15.4.1.2 Market Forecast (​2024-2034​)
15.4.2 Esophageal Cancer - Market Size by Therapies
15.4.2.1 Market Size by Therapies (​2018-2023​)
15.4.2.2 Market Forecast by Therapies (​2024-2034​)
15.4.3 Esophageal Cancer - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Esophageal Cancer - Market Size
15.5.1.1 Market Size (​2018-2023​)
15.5.1.2 Market Forecast (​2024-2034​)
15.5.2 Esophageal Cancer - Market Size by Therapies
15.5.2.1 Market Size by Therapies (​2018-2023​)
15.5.2.2 Market Forecast by Therapies (​2024-2034​)
15.5.3 Esophageal Cancer - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Esophageal Cancer - Market Size
15.6.1.1 Market Size (​2018-2023​)
15.6.1.2 Market Forecast (​2024-2034​)
15.6.2 Esophageal Cancer - Market Size by Therapies
15.6.2.1 Market Size by Therapies (​2018-2023​)
15.6.2.2 Market Forecast by Therapies (​2024-2034​)
15.6.3 Esophageal Cancer - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Esophageal Cancer - Market Size
15.7.1.1 Market Size (​2018-2023​)
15.7.1.2 Market Forecast (​2024-2034​)
15.7.2 Esophageal Cancer - Market Size by Therapies
15.7.2.1 Market Size by Therapies (​2018-2023​)
15.7.2.2 Market Forecast by Therapies (​2024-2034​)
15.7.3 Esophageal Cancer - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Esophageal Cancer - Market Size
15.8.1.1 Market Size (​2018-2023​)
15.8.1.2 Market Forecast (​2024-2034​)
15.8.2 Esophageal Cancer - Market Size by Therapies
15.8.2.1 Market Size by Therapies (​2018-2023​)
15.8.2.2 Market Forecast by Therapies (​2024-2034​)
15.8.3 Esophageal Cancer - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Esophageal Cancer - Market Size
15.9.1.1 Market Size (​2018-2023​)
15.9.1.2 Market Forecast (​2024-2034​)
15.9.2 Esophageal Cancer - Market Size by Therapies
15.9.2.1 Market Size by Therapies (​2018-2023​)
15.9.2.2 Market Forecast by Therapies (​2024-2034​)
15.9.3 Esophageal Cancer - Access and Reimbursement Overview
16 Esophageal Cancer - Recent Events and Inputs From Key Opinion Leaders
17 Esophageal Cancer Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Esophageal Cancer Market – Strategic Recommendations
19 Appendix

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