Cell-free Protein Expression Market Report by Product (Expression Systems, Reagents), Method (Transcription and Translation Systems, Translation Systems), Application (Enzyme Engineering, High Throughput Production, Protein Labeling, Protein-Protein Inter

Cell-free Protein Expression Market Report by Product (Expression Systems, Reagents), Method (Transcription and Translation Systems, Translation Systems), Application (Enzyme Engineering, High Throughput Production, Protein Labeling, Protein-Protein Interaction, Protein Purification), End User (Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, and Others), and Region 2024-2032


The global cell-free protein expression market size reached US$ 265.3 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 487.7 Million by 2032, exhibiting a growth rate (CAGR) of 6.86% during 2024-2032.

Cell-free protein expression (CFPE) refers to the production of desired recombinant proteins in solution using biomolecular translation machinery extracted from cells. It can be carried out using different cell lysates, such as E. coli, rabbit reticulocytes, wheat germ, insect cells, and mammalian cell-free protein expression systems. They are widely used in enzyme engineering, protein labeling, protein purification, protein-protein interaction, and high throughput production of mutants. CFPE is also used for analyzing components needed for protein stability, degradation, and folding. As compared to cell-based protein expression, cell-free protein expression is time efficient and convenient, allows the incorporation of non-natural amino acids, and provides enhanced stability and specificity.

Cell-free Protein Expression Market Trends:
The rapid advancement in biological sciences is one of the key factors driving the market growth. Cell-free protein expression is extensively used in the expansion of genetic code, assembly of viruses, and the synthesis of recombinant proteins for various biomolecular processes. Furthermore, the increasing technique utilization in the pharmaceutical industry for developing protein-based therapeutics, such as antibodies, antimicrobials, and cytokines, for treating cancer and infectious diseases is acting as another growth-inducing factor. Additionally, the integration of machine learning (ML) algorithms to improve protein production yield by optimizing the system for efficient prototyping and high-throughput experimentation is providing an impetus to market growth. Moreover, the introduction of novel processes to produce complex prokaryotic and eukaryotic proteins using a continuous-exchange cell-free (CECF) protein synthesis system is creating a positive outlook for the market. Other factors, including the widespread adoption of cell-free methods for biomanufacturing and prototyping, extensive research and development (R&D) activities in proteomics and genomics, and the rising adoption in the healthcare industry for diagnostic applications, such as pathogen sensing, inflammatory response, and personalized medicine, are supporting drive the market growth.

Key Market Segmentation:
IMARC Group provides an analysis of the key trends in each sub-segment of the global cell-free protein expression market report, along with forecasts at the global, regional and country level from 2024-2032. Our report has categorized the market based on product, method, application and end user.

Breakup by Product:

Expression Systems
E. coli Cell-free Protein Expression System
Wheat Germ Cell-free Protein Expression System
Rabbit Reticulocytes Cell-free Protein Expression System
Insect Cells Cell-free Protein Expression System
Human Cell-free Protein Expression System
Others
Reagents

Breakup by Method:

Transcription and Translation Systems
Translation Systems

Breakup by Application:

Enzyme Engineering
High Throughput Production
Protein Labeling
Protein-Protein Interaction
Protein Purification

Breakup by End User:

Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Others

Breakup by Region:

North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa

Competitive Landscape:
The competitive landscape of the industry has also been examined along with the profiles of the key players being Bioneer Corporation, biotechrabbit GmbH, Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.), CellFree Sciences Co. Ltd., Cube Biotech GmbH, GeneCopoeia Inc., Jena Bioscience GmbH, Merck KGaA, New England Biolabs, Promega Corporation, Takara Bio Inc. and Thermo Fisher Scientific Inc.

Key Questions Answered in This Report

1. What was the size of the global cell-free protein expression market in 2023?
2. What is the expected growth rate of the global cell-free protein expression market during 2024-2032?
3. What are the key factors driving the global cell-free protein expression market?
4. What has been the impact of COVID-19 on the global cell-free protein expression market?
5. What is the breakup of the global cell-free protein expression market based on the product?
6. What is the breakup of the global cell-free protein expression market based on the method?
7. What is the breakup of the global cell-free protein expression market based on application?
8. What is the breakup of the global cell-free protein expression market based on the end user?
9. What are the key regions in the global cell-free protein expression market?
10. Who are the key players/companies in the global cell-free protein expression market?


1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
4.1 Overview
4.2 Key Industry Trends
5 Global Cell-free Protein Expression Market
5.1 Market Overview
5.2 Market Performance
5.3 Impact of COVID-19
5.4 Market Forecast
6 Market Breakup by Product
6.1 Expression Systems
6.1.1 Market Trends
6.1.2 Key Segments
6.1.2.1 E. coli Cell-free Protein Expression System
6.1.2.2 Wheat Germ Cell-free Protein Expression System
6.1.2.3 Rabbit Reticulocytes Cell-free Protein Expression System
6.1.2.4 Insect Cells Cell-free Protein Expression System
6.1.2.5 Human Cell-free Protein Expression System
6.1.2.6 Others
6.1.3 Market Forecast
6.2 Reagents
6.2.1 Market Trends
6.2.2 Market Forecast
7 Market Breakup by Method
7.1 Transcription and Translation Systems
7.1.1 Market Trends
7.1.2 Market Forecast
7.2 Translation Systems
7.2.1 Market Trends
7.2.2 Market Forecast
8 Market Breakup by Application
8.1 Enzyme Engineering
8.1.1 Market Trends
8.1.2 Market Forecast
8.2 High Throughput Production
8.2.1 Market Trends
8.2.2 Market Forecast
8.3 Protein Labeling
8.3.1 Market Trends
8.3.2 Market Forecast
8.4 Protein-Protein Interaction
8.4.1 Market Trends
8.4.2 Market Forecast
8.5 Protein Purification
8.5.1 Market Trends
8.5.2 Market Forecast
9 Market Breakup by End User
9.1 Pharmaceutical and Biotechnology Companies
9.1.1 Market Trends
9.1.2 Market Forecast
9.2 Academic and Research Institutes
9.2.1 Market Trends
9.2.2 Market Forecast
9.3 Others
9.3.1 Market Trends
9.3.2 Market Forecast
10 Market Breakup by Region
10.1 North America
10.1.1 United States
10.1.1.1 Market Trends
10.1.1.2 Market Forecast
10.1.2 Canada
10.1.2.1 Market Trends
10.1.2.2 Market Forecast
10.2 Asia-Pacific
10.2.1 China
10.2.1.1 Market Trends
10.2.1.2 Market Forecast
10.2.2 Japan
10.2.2.1 Market Trends
10.2.2.2 Market Forecast
10.2.3 India
10.2.3.1 Market Trends
10.2.3.2 Market Forecast
10.2.4 South Korea
10.2.4.1 Market Trends
10.2.4.2 Market Forecast
10.2.5 Australia
10.2.5.1 Market Trends
10.2.5.2 Market Forecast
10.2.6 Indonesia
10.2.6.1 Market Trends
10.2.6.2 Market Forecast
10.2.7 Others
10.2.7.1 Market Trends
10.2.7.2 Market Forecast
10.3 Europe
10.3.1 Germany
10.3.1.1 Market Trends
10.3.1.2 Market Forecast
10.3.2 France
10.3.2.1 Market Trends
10.3.2.2 Market Forecast
10.3.3 United Kingdom
10.3.3.1 Market Trends
10.3.3.2 Market Forecast
10.3.4 Italy
10.3.4.1 Market Trends
10.3.4.2 Market Forecast
10.3.5 Spain
10.3.5.1 Market Trends
10.3.5.2 Market Forecast
10.3.6 Russia
10.3.6.1 Market Trends
10.3.6.2 Market Forecast
10.3.7 Others
10.3.7.1 Market Trends
10.3.7.2 Market Forecast
10.4 Latin America
10.4.1 Brazil
10.4.1.1 Market Trends
10.4.1.2 Market Forecast
10.4.2 Mexico
10.4.2.1 Market Trends
10.4.2.2 Market Forecast
10.4.3 Others
10.4.3.1 Market Trends
10.4.3.2 Market Forecast
10.5 Middle East and Africa
10.5.1 Market Trends
10.5.2 Market Breakup by Country
10.5.3 Market Forecast
11 SWOT Analysis
11.1 Overview
11.2 Strengths
11.3 Weaknesses
11.4 Opportunities
11.5 Threats
12 Value Chain Analysis
13 Porters Five Forces Analysis
13.1 Overview
13.2 Bargaining Power of Buyers
13.3 Bargaining Power of Suppliers
13.4 Degree of Competition
13.5 Threat of New Entrants
13.6 Threat of Substitutes
14 Price Analysis
15 Competitive Landscape
15.1 Market Structure
15.2 Key Players
15.3 Profiles of Key Players
15.3.1 Bioneer Corporation
15.3.1.1 Company Overview
15.3.1.2 Product Portfolio
15.3.1.3 Financials
15.3.2 biotechrabbit GmbH
15.3.2.1 Company Overview
15.3.2.2 Product Portfolio
15.3.3 Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.)
15.3.3.1 Company Overview
15.3.3.2 Product Portfolio
15.3.4 CellFree Sciences Co. Ltd.
15.3.4.1 Company Overview
15.3.4.2 Product Portfolio
15.3.5 Cube Biotech GmbH
15.3.5.1 Company Overview
15.3.5.2 Product Portfolio
15.3.6 GeneCopoeia Inc.
15.3.6.1 Company Overview
15.3.6.2 Product Portfolio
15.3.7 Jena Bioscience GmbH
15.3.7.1 Company Overview
15.3.7.2 Product Portfolio
15.3.8 Merck KGaA
15.3.8.1 Company Overview
15.3.8.2 Product Portfolio
15.3.8.3 Financials
15.3.8.4 SWOT Analysis
15.3.9 New England Biolabs
15.3.9.1 Company Overview
15.3.9.2 Product Portfolio
15.3.10 Promega Corporation
15.3.10.1 Company Overview
15.3.10.2 Product Portfolio
15.3.11 Takara Bio Inc.
15.3.11.1 Company Overview
15.3.11.2 Product Portfolio
15.3.11.3 Financials
15.3.12 Thermo Fisher Scientific Inc.
15.3.12.1 Company Overview
15.3.12.2 Product Portfolio
15.3.12.3 Financials
15.3.12.4 SWOT Analysis

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