Cell-free Protein Expression Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028

Cell-free Protein Expression Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028

Market Overview:

The global cell-free protein expression market size reached US$ 246.5 Million in 2022. Looking forward, IMARC Group expects the market to reach US$ 323.8 Million by 2028, exhibiting a growth rate (CAGR) of 7.61% during 2023-2028.

Cell-free protein expression (CFPE) refers to the production of desired recombinant proteins in solution using biomolecular translation machinery extracted from cells. It can be carried out using different cell lysates, such as E. coli, rabbit reticulocytes, wheat germ, insect cells, and mammalian cell-free protein expression systems. They are widely used in enzyme engineering, protein labeling, protein purification, protein-protein interaction, and high throughput production of mutants. CFPE is also used for analyzing components needed for protein stability, degradation, and folding. As compared to cell-based protein expression, cell-free protein expression is time efficient and convenient, allows the incorporation of non-natural amino acids, and provides enhanced stability and specificity.

Cell-free Protein Expression Market Trends:

The rapid advancement in biological sciences is one of the key factors driving the market growth. Cell-free protein expression is extensively used in the expansion of genetic code, assembly of viruses, and the synthesis of recombinant proteins for various biomolecular processes. Furthermore, the increasing technique utilization in the pharmaceutical industry for developing protein-based therapeutics, such as antibodies, antimicrobials, and cytokines, for treating cancer and infectious diseases is acting as another growth-inducing factor. Additionally, the integration of machine learning (ML) algorithms to improve protein production yield by optimizing the system for efficient prototyping and high-throughput experimentation is providing an impetus to market growth. Moreover, the introduction of novel processes to produce complex prokaryotic and eukaryotic proteins using a continuous-exchange cell-free (CECF) protein synthesis system is creating a positive outlook for the market. Other factors, including the widespread adoption of cell-free methods for biomanufacturing and prototyping, extensive research and development (R&D) activities in proteomics and genomics, and the rising adoption in the healthcare industry for diagnostic applications, such as pathogen sensing, inflammatory response, and personalized medicine, are supporting drive the market growth.

Key Market Segmentation:

IMARC Group provides an analysis of the key trends in each sub-segment of the global cell-free protein expression market report, along with forecasts at the global, regional and country level from 2023-2028. Our report has categorized the market based on product, method, application and end user.

Breakup by Product:

Expression Systems
E. coli Cell-free Protein Expression System
Wheat Germ Cell-free Protein Expression System
Rabbit Reticulocytes Cell-free Protein Expression System
Insect Cells Cell-free Protein Expression System
Human Cell-free Protein Expression System
Others
Reagents

Breakup by Method:

Transcription and Translation Systems
Translation Systems

Breakup by Application:

Enzyme Engineering
High Throughput Production
Protein Labeling
Protein-Protein Interaction
Protein Purification

Breakup by End User:

Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Others

Breakup by Region:
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa

Competitive Landscape:

The competitive landscape of the industry has also been examined along with the profiles of the key players being Bioneer Corporation, biotechrabbit GmbH, Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.), CellFree Sciences Co. Ltd., Cube Biotech GmbH, GeneCopoeia Inc., Jena Bioscience GmbH, Merck KGaA, New England Biolabs, Promega Corporation, Takara Bio Inc. and Thermo Fisher Scientific Inc.

Key Questions Answered in This Report:

How has the global cell-free protein expression market performed so far and how will it perform in the coming years?
What has been the impact of COVID-19 on the global cell-free protein expression market?
What are the key regional markets?
What is the breakup of the market based on the product?
What is the breakup of the market based on the method?
What is the breakup of the market based on the application?
What is the breakup of the market based on the end user?
What are the various stages in the value chain of the industry?
What are the key driving factors and challenges in the industry?
What is the structure of the global cell-free protein expression market and who are the key players?
What is the degree of competition in the industry?