Ankylosing Spondylitis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

Ankylosing Spondylitis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034


The 7 major ankylosing spondylitis markets reached a value of US$ 4.8 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 9.3 Billion by 2034, exhibiting a growth rate (CAGR) of 6.3% during 2024-2034.

The ankylosing spondylitis (AS) market has been comprehensively analyzed in IMARC's new report titled "Ankylosing Spondylitis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the joints of the spine, leading to stiffness and pain. The symptoms of AS often begin in the sacroiliac joints (the joints between the base of the spine and the pelvis) and can eventually lead to the fusion of the spinal bones, resulting in a loss of mobility and flexibility in the spine. It is classified as a type of inflammatory arthritis and is considered a lifelong condition. The onset of the disease usually starts in early adulthood and is more common in men than in women. The symptoms of AS can vary but typically involve back pain and stiffness, pain and swelling in other parts of the body caused by inflammation of the joints (arthritis), soreness where a tendon joins a bone (enthesitis), and extreme tiredness (fatigue). A diagnosis of AS can usually be confirmed if an X-ray shows inflammation of the sacroiliac joints (sacroiliitis) and the patient must have at least 1 of the following conditions: at least three months of lower back pain that doesn't improve with rest, limited movement in the lower back (lumbar spine), or limited chest expansion.

The increasing prevalence of inflammatory arthritis coupled with the rising demand for effective therapies that can treat this condition is primarily driving the global ankylosing spondylitis market. In addition to this, the growing awareness regarding the early diagnosis and treatment of ankylosing spondylitis as well as the importance of long-term management of the disease, is also propelling the market growth. Moreover, the escalating requirement for biologic medications, which are more effective in treating ankylosing spondylitis than traditional non-biologic medications, is further creating a positive outlook for the market. These drugs target specific molecules that are involved in the inflammatory process and have been shown to be potent in reducing symptoms of the disease. Apart from this, the emerging popularity of disease-modifying anti-rheumatic drugs (DMARDs) since they assist in slowing the disease progression is also bolstering the market growth. Moreover, the widespread adoption of physical rehabilitation and therapy to maintain mobility and flexibility and prevent the spinal fusion that can occur in advanced cases of the disease is further propelling the global market. Besides this, several key players are making extensive investments in research and development activities to understand the disease and its underlying mechanisms in order to introduce novel treatments that can target specific pathways involved. This, in turn, is acting as another significant growth-inducing factor. Additionally, the rising popularity of numerous innovative approaches to treatment, including combination therapy in patients who have failed other medications, is expected to drive the global ankylosing spondylitis market during the forecasted period.

IMARC Group's new report provides an exhaustive analysis of the ankylosing spondylitis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for ankylosing spondylitis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the ankylosing spondylitis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the ankylosing spondylitis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the ankylosing spondylitis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current ankylosing spondylitis-marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the ankylosing spondylitis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the ankylosing spondylitis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the ankylosing spondylitis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of ankylosing spondylitis across the seven major markets?
What is the number of prevalent cases (2018-2034) of ankylosing spondylitis by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of ankylosing spondylitis by gender across the seven major markets?
What is the number of prevalent cases (2018-2034) of ankylosing spondylitis by type across the seven major markets?
How many patients are diagnosed (2018-2034) with ankylosing spondylitis across the seven major markets?
What is the size of the ankylosing spondylitis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of ankylosing spondylitis?
What will be the growth rate of patients across the seven major markets?

Ankylosing Spondylitis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for ankylosing spondylitis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the ankylosing spondylitis market?
What are the key regulatory events related to the ankylosing spondylitis market?
What is the structure of clinical trial landscape by status related to the ankylosing spondylitis market?
What is the structure of clinical trial landscape by phase related to the ankylosing spondylitis market?
What is the structure of clinical trial landscape by route of administration related to the ankylosing spondylitis market?


1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Ankylosing Spondylitis - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Ankylosing Spondylitis - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Ankylosing Spondylitis - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (​2018-2034​)
7.2.4 Epidemiology by Gender (​2018-2034​)
7.2.5 Epidemiology by Type (​2018-2034​)
7.2.6 Diagnosed Cases (​2018-2034​)
7.2.7 Patient Pool/Treated Cases (​2018-2034​)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (​2018-2034​)
7.3.4 Epidemiology by Gender (​2018-2034​)
7.3.5 Epidemiology by Type (​2018-2034​)
7.3.6 Diagnosed Cases (​2018-2034​)
7.3.7 Patient Pool/Treated Cases (​2018-2034​)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (​2018-2034​)
7.4.4 Epidemiology by Gender (​2018-2034​)
7.4.5 Epidemiology by Type (​2018-2034​)
7.4.6 Diagnosed Cases (​2018-2034​)
7.4.7 Patient Pool/Treated Cases (​2018-2034​)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (​2018-2034​)
7.5.4 Epidemiology by Gender (​2018-2034​)
7.5.5 Epidemiology by Type (​2018-2034​)
7.5.6 Diagnosed Cases (​2018-2034​)
7.5.7 Patient Pool/Treated Cases (​2018-2034​)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (​2018-2034​)
7.6.4 Epidemiology by Gender (​2018-2034​)
7.6.5 Epidemiology by Type (​2018-2034​)
7.6.6 Diagnosed Cases (​2018-2034​)
7.6.7 Patient Pool/Treated Cases (​2018-2034​)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (​2018-2034​)
7.7.4 Epidemiology by Gender (​2018-2034​)
7.7.5 Epidemiology by Type (​2018-2034​)
7.7.6 Diagnosed Cases (​2018-2034​)
7.7.7 Patient Pool/Treated Cases (​2018-2034​)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (​2018-2034​)
7.8.4 Epidemiology by Gender (​2018-2034​)
7.8.5 Epidemiology by Type (​2018-2034​)
7.8.6 Diagnosed Cases (​2018-2034​)
7.8.7 Patient Pool/Treated Cases (​2018-2034​)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (​2018-2034​)
7.9.4 Epidemiology by Gender (​2018-2034​)
7.9.5 Epidemiology by Type (​2018-2034​)
7.9.6 Diagnosed Cases (​2018-2034​)
7.9.7 Patient Pool/Treated Cases (​2018-2034​)
8 Ankylosing Spondylitis - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Ankylosing Spondylitis - Unmet Needs
10 Ankylosing Spondylitis - Key Endpoints of Treatment
11 Ankylosing Spondylitis - Marketed Products
11.1 List of Ankylosing Spondylitis Marketed Drugs Across the Top 7 Markets
11.1.1 RINVOQ- AbbVie
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 XELJANZ - Pfizer
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 TALTZ - Eli Lilly
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 SIMPONI - Janssen Biotech
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Remicade (infliximab) – Janssen Biotech
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 Ankylosing Spondylitis - Pipeline Drugs
12.1 List of Ankylosing Spondylitis Pipeline Drugs Across the Top 7 Markets
12.1.1 AK111 - Akeso
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Secukinumab - Novartis Pharmaceutical
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Bimekizumab - UCB Biopharma SRL
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 CC-99677 - Celgene
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs and the complete list has been provided in the report.
13. Ankylosing Spondylitis - Attribute Analysis of Key Marketed and Pipeline Drugs
14. Ankylosing Spondylitis – Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Ankylosing Spondylitis - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Ankylosing Spondylitis - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Ankylosing Spondylitis - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Ankylosing Spondylitis - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Ankylosing Spondylitis - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Ankylosing Spondylitis - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Ankylosing Spondylitis - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Ankylosing Spondylitis - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Ankylosing Spondylitis - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Ankylosing Spondylitis - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Ankylosing Spondylitis - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Ankylosing Spondylitis - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Ankylosing Spondylitis - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Ankylosing Spondylitis - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Ankylosing Spondylitis - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Ankylosing Spondylitis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Ankylosing Spondylitis - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Ankylosing Spondylitis - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Ankylosing Spondylitis - Access and Reimbursement Overview
16 Ankylosing Spondylitis - Recent Events and Inputs From Key Opinion Leaders
17 Ankylosing Spondylitis Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Ankylosing Spondylitis – Strategic Recommendations
19 Appendix

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