Mixed Mode Chromatography Resin Market Size, Share & Trends Analysis Report By Technique (Ion Exchange-Hydrophobic, Hydroxyapatite), By End-use (Pharmaceutical & Biotechnology), By Region, And Segment Forecasts, 2025 - 2030

Mixed Mode Chromatography Resin Market Size, Share & Trends Analysis Report By Technique (Ion Exchange-Hydrophobic, Hydroxyapatite), By End-use (Pharmaceutical & Biotechnology), By Region, And Segment Forecasts, 2025 - 2030

Mixed Mode Chromatography Resin Market Growth & Trends

The global mixed mode chromatography resin market size is expected to reach USD 223.9 million by 2030, registering a CAGR of 12.3% from 2025 to 2030, according to a new report by Grand View Research, Inc. Growing number of contract manufacturing organizations (CMOs) and contract research organizations (CROs), along with increasing use of chromatography resin in separation of monoclonal antibodies, is anticipated to propel the market.

The Ion exchange - Hydrophobic resin segment is expected to dominate the global market till 2025. Demand for this technique is attributed to growth in drug discovery by pharmaceutical companies. These companies use chromatography techniques to separate complex mixtures and purification of materials. Increasing number of epidemic diseases such as Zika and Ebola is expected to further boost the mixed mode chromatography resin market.

Asia Pacific, especially China and India, is expected to generate significant demand for mixed mode chromatography resin owing to growing pharmaceutical sector, coupled with abundance of high skilled workforce and increase in disposable income.

Presence of global pharmaceutical and biotechnology companies, along with their research and development facilities, has enabled North America to be a key market for mixed mode chromatography resin. Massive healthcare expenditure is also driving the expansion of the market in this region.

Mixed Mode Chromatography Resin Market Report Highlights

• The pharmaceutical and biotechnology segment led the market and is expected to grow at a CAGR of 12.3% from 2025 to 2030, owing to increasing investments in biopharmaceutical research and development, particularly for novel therapies like monoclonal antibodies and gene therapies, heightening the demand for effective purification techniques.
• The ion exchange and hydrophobic interaction segment dominated the market and accounted for the largest revenue share of 50.8% in 2024 attributed to its effectiveness in separating biomolecules based on charge and hydrophobicity.
• The mixed mode chromatography resin market in North America dominated the global market and accounted for the largest revenue share of 35.3% in 2024 attributed to the strong presence of pharmaceutical and biotechnology companies.
• The mixed mode chromatography resin market in Asia Pacific is expected to grow at a CAGR of 8.3% over the forecast period. This growth is attributed to increasing investments in biopharmaceuticals and rising healthcare expenditures.

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