High-performance Liquid Chromatography Market Size, Share & Trends Analysis Report By Product (Instruments, Consumables & Accessories, Software), By Application, By End-use, By Region, And Segment Forecasts, 2025 - 2030
High-performance Liquid Chromatography Market Growth & Trends
The global high-performance liquid chromatography market size is expected to reach USD 7.03 billion by 2030, registering a CAGR of 6.0% from 2025 to 2030, according to a new report by Grand View Research, Inc. Rapid growth in pharmaceutical production, stringent regulatory norms for drug purity, and increasing adoption of high-performance liquid chromatography (HPLC) techniques for diagnostics and research purposes are driving the market.
HPLC is commonly used for the assessment of drug purity on an industrial scale. It also enables characterization of molecules being explored as potential new drug candidates. Demand for the technique is anticipated to grow due to its increasing applications in ensuring consistency and determination of dosage of active pharmaceutical ingredients. Furthermore, the technique holds significance in quality control testing for assuring the fulfillment of critical quality attributes in the pharmaceutical industry.
The technique is augmenting clinical diagnostic services due to the availability of improved stationary phase alternatives and multiple channel HPLC instruments that can aid in sequential analysis of patient samples. Such attributes are desirable for low- or moderate-throughput laboratories and enable faster turnaround times. Similarly, recent developments in column technologies are increasing the efficiency of HPLC operations and are likely to fuel the market growth. For instance, the advent of>2-µm superficially porous silica particles has led to improved HPLC operations at comparatively lower back-pressure and with the use of shorter columns.
Furthermore, companies involved in the market are launching new HPLC-based analyzers and systems for capitalizing on the expanding scope of applications for the technique. For instance, in June 2021, Trivitron Healthcare launched two new HPLC analyzers, NANO H5 & NANO H110, intended for the detection of HbA1c and Hb variants in less than three minutes.
In addition, the COVID-19 pandemic has accelerated the adoption of HPLC systems for the development of new therapeutics, vaccines, and reliable diagnostic methods for the disease. Furthermore, epidemiological applications of the technique for the characterization of viral proteins are expected to gain traction due to the emerging mutations of the SARS-CoV-2 virus. These factors are anticipated to positively affect the market growth.
High-performance Liquid Chromatography Market Report Highlights
- By product, the instruments segment held the largest revenue share of 48.2% in 2024 due to the increasing dominance of integrated HPLC systems and the availability of advanced detectors.
- Based on application, Clinical research applications accounted for the largest revenue share of 40.7% in 2024. This growth can be linked to the increasing scope of clinical trial activities, a rise in biopharmaceutical research and development, and a growing demand for high-throughput analytical techniques.
- By end-user, pharmaceutical and biotechnology companies dominated the market and accounted for 41.9% share in 2024. Within these companies, HPLC methods are employed for various applications, including quality control, drug purity determination, characterization of drug candidates, and evaluation of the stability of active ingredients in pharmaceuticals.
- The North America market dominated the overall global market and accounted for the 31.68% of revenue share in 2024.
- The Asia Pacific market is experiencing the fastest growth, driven by significant innovations in healthcare infrastructure and technology.
- Chapter 1. Methodology and Scope
- 1.1. Market Segmentation and Scope
- 1.2. Segment Definitions
- 1.2.1. Product
- 1.2.2. Application
- 1.2.3. End Use
- 1.2.4. Regional Scope
- 1.2.5. Estimates and forecasts timeline
- 1.3. Research Methodology
- 1.4. Information Procurement
- 1.4.1. Purchased database
- 1.4.2. GVR’s internal database
- 1.4.4. Primary research
- 1.4.5. Details of primary research
- 1.5. Information or Data Analysis
- 1.5.1. Data analysis models
- 1.6. Market Formulation & Validation
- 1.7. Model Details
- 1.7.1. Commodity flow analysis (Model 1)
- 1.7.2. Approach 1: Commodity flow approach
- 1.7.3. Volume price analysis (Model 2)
- 1.7.4. Approach 2: Volume price analysis
- 1.8. List of Secondary Sources
- 1.9. List of Primary Sources
- 1.10. Objectives
- Chapter 2. Executive Summary
- 2.1. Market Outlook
- 2.2. Segment Outlook
- 2.3. Regional outlook
- 2.4. Competitive Insights
- Chapter 3. High-performance Liquid Chromatography Market Variables, Trends & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent Market Outlook
- 3.1.2. Related/ancillary market outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.1.1. Technological Advancements In HPLC Systems
- 3.2.1.2. Increasing Adoption Of HPLC Techniques In The Pharmaceutical Industry
- 3.2.1.3. Increasing Availability Of HPLC Method Development Systems And Support Software
- 3.2.2. Market Restraint Analysis
- 3.2.2.1. High Instrumentation Costs
- 3.2.2.2. Lack of Skilled Personnel
- 3.3. High-performance Liquid Chromatography Market Analysis Tools
- 3.3.1. Industry Analysis – Porter’s
- 3.3.1.1. Bargaining power of suppliers
- 3.3.1.2. Bargaining power of buyers
- 3.3.1.3. Threat of substitutes
- 3.3.1.4. Threat of new entrants
- 3.3.1.5. Competitive rivalry
- 3.3.2. PESTEL Analysis
- 3.3.2.1. Political landscape
- 3.3.2.2. Economic landscape
- 3.3.2.3. Social landscape
- 3.3.2.4. Technological landscape
- 3.3.2.5. Environmental landscape
- 3.3.2.6. Legal landscape
- Chapter 4. High-performance Liquid Chromatography Market: Product Estimates & Trend Analysis
- 4.1. Segment Dashboard
- 4.2. High-performance Liquid Chromatography Market: Product Movement Analysis
- 4.3. High-performance Liquid Chromatography Market by Product Outlook (USD Billion)
- 4.4. Market Size & Forecasts and Trend Analyses, 2018 to 2030 for the following
- 4.5. Instruments
- 4.5.1. Instruments Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.5.2. HPLC Systems
- 4.5.2.1. HPLC Systems Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.5.3. Pumps
- 4.5.3.1. Pumps Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.5.4. Detectors
- 4.5.4.1. Detectors Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.5.5. Others
- 4.5.5.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6. Consumables & Accessories
- 4.6.1. Consumables & Accessories Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2. Columns
- 4.6.2.1. Reagents Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2.2. Reverse-phase HPLC columns
- 4.6.2.2.1. Reverse-phase HPLC columns Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2.3. Normal-phase HPLC columns
- 4.6.2.3.1. Normal-phase HPLC columns Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2.4. Ion exchange HPLC columns
- 4.6.2.4.1. Ion exchange HPLC columns Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2.5. Size exclusion HPLC columns
- 4.6.2.5.1. Size exclusion HPLC columns Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.2.6. Other HPLC columns
- 4.6.2.6.1. Other HPLC columns Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.3. Filters
- 4.6.3.1. Filters Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.4. Vials
- 4.6.4.1. Vials Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.5. Tubes
- 4.6.5.1. Tubes Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.6.6. Others
- 4.6.6.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 4.7. Software
- 4.7.1. Software Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- Chapter 5. High-performance Liquid Chromatography Market: Application Estimates & Trend Analysis
- 5.1. Segment Dashboard
- 5.2. High-performance Liquid Chromatography Market: Application Movement Analysis
- 5.3. High-performance Liquid Chromatography Market by Application Outlook (USD Billion)
- 5.4. Market Size & Forecasts and Trend Analyses, 2018 to 2030 for the following
- 5.5. Clinical Research Applications
- 5.5.1. Clinical Research Applications Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 5.6. Diagnostic Applications
- 5.6.1. Diagnostic Applications Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 5.7. Forensic Applications
- 5.7.1. Forensic Applications Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 5.8. Other Applications
- 5.8.1. Other Applications Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- Chapter 6. High-performance Liquid Chromatography Market: End Use Estimates & Trend Analysis
- 6.1. Segment Dashboard
- 6.2. High-performance Liquid Chromatography Market: End Use Movement Analysis
- 6.3. High-performance Liquid Chromatography Market by End Use Outlook (USD Billion)
- 6.4. Market Size & Forecasts and Trend Analyses, 2018 to 2030 for the following
- 6.5. Pharmaceutical & Biotechnology Companies
- 6.5.1. Pharmaceutical & Biotechnology Companies Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 6.6. Academic & Research Institutes
- 6.6.1. Academic & Research Institutes Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- 6.7. Others
- 6.7.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Billion)
- Chapter 7. High-performance Liquid Chromatography Market: Regional Estimates & Trend Analysis
- 7.1. Regional Dashboard
- 7.2. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 7.3. North America
- 7.3.1. U.S.
- 7.3.1.1. Key country dynamics
- 7.3.1.2. Regulatory framework/ reimbursement structure
- 7.3.1.3. Competitive scenario
- 7.3.1.4. U.S. market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.3.2. Canada
- 7.3.2.1. Key country dynamics
- 7.3.2.2. Regulatory framework/ reimbursement structure
- 7.3.2.3. Competitive scenario
- 7.3.2.4. Canada market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.3.3. Mexico
- 7.3.3.1. Key country dynamics
- 7.3.3.2. Regulatory framework/ reimbursement structure
- 7.3.3.3. Competitive scenario
- 7.3.3.4. Mexico market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4. Europe
- 7.4.1. UK
- 7.4.1.1. Key country dynamics
- 7.4.1.2. Regulatory framework/ reimbursement structure
- 7.4.1.3. Competitive scenario
- 7.4.1.4. UK market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.2. Germany
- 7.4.2.1. Key country dynamics
- 7.4.2.2. Regulatory framework/ reimbursement structure
- 7.4.2.3. Competitive scenario
- 7.4.2.4. Germany market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.3. France
- 7.4.3.1. Key country dynamics
- 7.4.3.2. Regulatory framework/ reimbursement structure
- 7.4.3.3. Competitive scenario
- 7.4.3.4. France market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.4. Italy
- 7.4.4.1. Key country dynamics
- 7.4.4.2. Regulatory framework/ reimbursement structure
- 7.4.4.3. Competitive scenario
- 7.4.4.4. Italy market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.5. Spain
- 7.4.5.1. Key country dynamics
- 7.4.5.2. Regulatory framework/ reimbursement structure
- 7.4.5.3. Competitive scenario
- 7.4.5.4. Spain market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.6. Norway
- 7.4.6.1. Key country dynamics
- 7.4.6.2. Regulatory framework/ reimbursement structure
- 7.4.6.3. Competitive scenario
- 7.4.6.4. Norway market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.7. Sweden
- 7.4.7.1. Key country dynamics
- 7.4.7.2. Regulatory framework/ reimbursement structure
- 7.4.7.3. Competitive scenario
- 7.4.7.4. Sweden market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.4.8. Denmark
- 7.4.8.1. Key country dynamics
- 7.4.8.2. Regulatory framework/ reimbursement structure
- 7.4.8.3. Competitive scenario
- 7.4.8.4. Denmark market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5. Asia Pacific
- 7.5.1. Japan
- 7.5.1.1. Key country dynamics
- 7.5.1.2. Regulatory framework/ reimbursement structure
- 7.5.1.3. Competitive scenario
- 7.5.1.4. Japan market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5.2. China
- 7.5.2.1. Key country dynamics
- 7.5.2.2. Regulatory framework/ reimbursement structure
- 7.5.2.3. Competitive scenario
- 7.5.2.4. China market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5.3. India
- 7.5.3.1. Key country dynamics
- 7.5.3.2. Regulatory framework/ reimbursement structure
- 7.5.3.3. Competitive scenario
- 7.5.3.4. India market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5.4. Australia
- 7.5.4.1. Key country dynamics
- 7.5.4.2. Regulatory framework/ reimbursement structure
- 7.5.4.3. Competitive scenario
- 7.5.4.4. Australia market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5.5. South Korea
- 7.5.5.1. Key country dynamics
- 7.5.5.2. Regulatory framework/ reimbursement structure
- 7.5.5.3. Competitive scenario
- 7.5.5.4. South Korea market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.5.6. Thailand
- 7.5.6.1. Key country dynamics
- 7.5.6.2. Regulatory framework/ reimbursement structure
- 7.5.6.3. Competitive scenario
- 7.5.6.4. Thailand market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.6. Latin America
- 7.6.1. Brazil
- 7.6.1.1. Key country dynamics
- 7.6.1.2. Regulatory framework/ reimbursement structure
- 7.6.1.3. Competitive scenario
- 7.6.1.4. Brazil market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.6.2. Argentina
- 7.6.2.1. Key country dynamics
- 7.6.2.2. Regulatory framework/ reimbursement structure
- 7.6.2.3. Competitive scenario
- 7.6.2.4. Argentina market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.7. MEA
- 7.7.1. South Africa
- 7.7.1.1. Key country dynamics
- 7.7.1.2. Regulatory framework/ reimbursement structure
- 7.7.1.3. Competitive scenario
- 7.7.1.4. South Africa market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.7.2. Saudi Arabia
- 7.7.2.1. Key country dynamics
- 7.7.2.2. Regulatory framework/ reimbursement structure
- 7.7.2.3. Competitive scenario
- 7.7.2.4. Saudi Arabia market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.7.3. UAE
- 7.7.3.1. Key country dynamics
- 7.7.3.2. Regulatory framework/ reimbursement structure
- 7.7.3.3. Competitive scenario
- 7.7.3.4. UAE market estimates and forecasts 2018 to 2030 (USD Billion)
- 7.7.4. Kuwait
- 7.7.4.1. Key country dynamics
- 7.7.4.2. Regulatory framework/ reimbursement structure
- 7.7.4.3. Competitive scenario
- 7.7.4.4. Kuwait market estimates and forecasts 2018 to 2030 (USD Billion)
- Chapter 8. Competitive Landscape
- 8.1. Market Participant Categorization
- 8.2. Recent Developments & Impact Analysis by Key Market Participants
- 8.3. Company Market Share Analysis, 2024
- 8.4. Key Company Profiles
- 8.4.1. WATERS CORPORATION
- 8.4.1.1. Company overview
- 8.4.1.2. Financial performance
- 8.4.1.3. Product benchmarking
- 8.4.1.4. Strategic initiatives
- 8.4.2. THERMO FISHER SCIENTIFIC, INC.
- 8.4.2.1. Company overview
- 8.4.2.2. Financial performance
- 8.4.2.3. Product benchmarking
- 8.4.2.4. Strategic initiatives
- 8.4.3. AGILENT TECHNOLOGIES, INC
- 8.4.3.1. Company overview
- 8.4.3.2. Financial performance
- 8.4.3.3. Product benchmarking
- 8.4.3.4. Strategic initiatives
- 8.4.4. SHIMADZU CORPORATION
- 8.4.4.1. Company overview
- 8.4.4.2. Financial performance
- 8.4.4.3. Product benchmarking
- 8.4.4.4. Strategic initiatives
- 8.4.5. SARTORIUS AG
- 8.4.5.1. Company overview
- 8.4.5.2. Financial performance
- 8.4.5.3. Product benchmarking
- 8.4.5.4. Strategic initiatives
- 8.4.6. PERKINELMER, INC
- 8.4.6.1. Company overview
- 8.4.6.2. Financial performance
- 8.4.6.3. Product benchmarking
- 8.4.6.4. Strategic initiatives
- 8.4.7. BIO-RAD LABORATORIES, INC
- 8.4.7.1. Company overview
- 8.4.7.2. Financial performance
- 8.4.7.3. Product benchmarking
- 8.4.7.4. Strategic initiatives
- 8.4.8. MERCK KGAA
- 8.4.8.1. Company overview
- 8.4.8.2. Financial performance
- 8.4.8.3. Product benchmarking
- 8.4.8.4. Strategic initiatives
- 8.4.9. TOSOH BIOSCIENCE GMBH
- 8.4.9.1. Company overview
- 8.4.9.2. Financial performance
- 8.4.9.3. Product benchmarking
- 8.4.9.4. Strategic initiatives
- 8.4.10. DANAHER CORPORATION
- 8.4.10.1. Company overview
- 8.4.10.2. Financial performance
- 8.4.10.3. Product benchmarking
- 8.4.10.4. Strategic initiatives
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