Non-Small Cell Lung Cancer Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

Non-Small Cell Lung Cancer Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

Summary

This reports provides a data-driven overview of the current and future competitive landscape in NSCLC therapeutics.

Synopsis

  • In 2022, there will be more than 1.5 million diagnosed prevalent cases of NSCLC across 16 pharmaceutical markets.
  • There are 46 marketed innovator drugs for the treatment of NSCLC, mostly protein/peptide inhibitors and receptor antagonists.
  • R&D activity in NSCLC is high globally, with 24 products in pre-registration and 101 products in Phase III development.
  • Commercial sponsors dominate clinical trial development in NSCLC, with Canada, UK and the US emerging as the key countries for conducting Phase III trials in NSCLC.
  • During the past 12 months, 28 strategic alliances involving NSCLC assets were successfully completed.
  • Key players in the marketed drugs space for NSCLC are more inclined towards life cycle management, while emerging players are focused on launching novel investigational drugs for the treatment on a global scale.
Scope

GlobalData’s NSCLC: Competitive Landscape combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include -
  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Retail or Manufacturer Price of Products
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts
Reasons to Buy
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the NSCLC market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global NSCLC market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.


  • Report scope
  • Abbreviations
  • Key Findings
  • Disease Overview
  • Epidemiology Overview
    • Epidemiology Overview: Diagnosed Prevalent Cases of NSCLC in 2022 and 2027
  • Treatment Guidelines
  • Marketed Drugs Assessment
    • Marketed Drugs - Leading Marketed Drugs in NSCLC
    • Marketed Drugs - Overview by Mechanism of Action
    • Marketed Drugs - Overview by Route of Administration
    • Marketed Drugs - Overview by Molecule Type
    • Marketed Drug Profile: Merck's Keytruda
    • Marketed Drug Profile: Bristol Myers Squibb/Ono Pharma's Opdivo/Opdyta
    • Marketed Drug Profile: AstraZeneca's Tagrisso
    • Marketed Drug Profile: Roche's Tecentriq
    • Marketed Drug Profile: Roche's Avastin
    • Marketed Drug Profile: AstraZeneca's Imfinzi
    • Marketed Drug Profile: Novartis's Mekinist
    • Marketed Drug Profile: Bristol Myers Squibb's Yervoy
    • Marketed Drug Profile: Novartis's Tafinlar + Mekinist
    • Marketed Drug Profile: Roche's Alecensa
    • Marketed Drug Profile: Eli Lilly's Cyramza
    • Marketed Drug Profile: Pfizer's Xalkori
    • Marketed Drug Profile: Regeneron's Libtayo
    • Marketed Drug Profile: Merck Serono's Tepmetko
    • Marketed Drug Profile: Pfizer's Lorbrena/Lorviqua/Lorlak
    • Marketed Drug Profile: Takeda's Alunbrig
    • Marketed Drug Profile: Loxo's Retevmo
    • Marketed Drug Profile: Novartis's Tabrecta
    • Marketed Drug Profile: Amgen's Lumakras/Lumykras
    • Marketed Drug Profile: Blueprint's Gavreto
    • Marketed Drug Profile: Novartis's Zykadia
    • Marketed Drug Profile: Roche's Rozlytrek
    • Marketed Drug Profile : Novartis's Tafinlar
    • Marketed Drug Profile: Janssen's Rybrevant
    • Marketed Drug Profile: Pfizer's Vizimpro
    • Marketed Drug Profile: Takeda's Exkivit; Exkivity
    • Marketed Drug Profile: Astellas/Roche's Tarceva
    • Marketed Drug Profile: Boehringer's Gilotrif/Giotrif/Xovoltib
    • Marketed Drug Profile: Boehringer's Vargatef/Cyendiv/Ofev
    • Marketed Drug Profile: AstraZeneca's Gefitinib/Iressa
    • Marketed Drug Profile: Eli Lilly's Portrazza
  • Pricing and Reimbursement Assessment
    • Marketed Drugs - Manufacturer Price for Intravenous Formulations in NSCLC
    • Marketed Drugs - Manufacturer Price for Oral Formulations in NSCLC
    • Marketed Drugs - Manufacturer Price ($/mg)
    • Marketed Drugs - Time to Pricing and Reimbursement for Pembrolizumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Nivolumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Atezolizumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Durvalumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Ipilumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Alectinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Ramucirumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Cemiplimab
    • Marketed Drugs - Time to Pricing and Reimbursement for Amivantamab
    • Marketed Drugs - Time to Pricing and Reimbursement for Bevacizumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Ceritinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Dacomitinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Nintedanib
    • Marketed Drugs - Time to Pricing and Reimbursement for Necitumumab
    • Marketed Drugs - Time to Pricing and Reimbursement for Trametinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Osimertinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Lorlatinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Brigatinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Capmatinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Selpercatinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Sotorasib
    • Marketed Drugs - Time to Pricing and Reimbursement for Entrectinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Pralsetinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Dabrafenib
    • Marketed Drugs - Time to Pricing and Reimbursement for Afatinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Erlotinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Tepotinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Crizotinib
    • Marketed Drugs - Time to Pricing and Reimbursement for Gefitinib
  • Pipeline Drugs Assessment
    • Pipeline Drugs Overview - Pre-registration and Phase III Pipeline Drugs in NSCLC
    • Pipeline Drugs - Overview by Development Stage
    • Pipeline Drugs - Overview by Mechanism of Action
    • Pipeline Drugs - Overview by Route of Administration
    • Pipeline Drugs - Overview by Molecule Type
    • Pipeline Drugs - Drug-Specific PTSR and LoA in NSCLC
    • Pipeline Drugs - PTSRs and LoAs in Oncology and in NSCLC
  • Clinical Trials Assessment
    • Clinical Trials in NSCLC - Historical Overview
    • Clinical Trials in NSCLC - Overview by Phase
    • Clinical Trials in NSCLC - Overview by Status
    • Clinical Trials in NSCLC - Overview by Phase for Ongoing and Planned Trials
    • Clinical Trials in NSCLC - Trials with a Virtual Component
    • Clinical Trials in NSCLC - Geographic Overview
    • Clinical Trials in NSCLC - Single-Country and Multinational Trials by Region
    • Clinical Trials in NSCLC - Top 20 Sponsors with Breakdown by Phase
    • Clinical Trials in NSCLC - Top 20 Sponsors with Breakdown by Status
    • Clinical Trials in NSCLC - Overview by Endpoint Status
    • Clinical Trials in NSCLC - Overview by Race and Ethnicity
    • Clinical Trials in NSCLC - Enrollment Data
    • Clinical Trials in NSCLC - Overview of Sites by Geography
    • Clinical Trials in NSCLC - Top 20 Countries for Trial Sites
    • Clinical Trials in NSCLC - Top 20 Sites Globally
    • Clinical Trials - Feasibility Analysis: Geography Overview
    • Clinical Trials - Feasibility Analysis: Benchmark Models for NSCLC
  • Deals Landscape
    • Deals Landscape - Mergers, Acquisitions, and Strategic Alliances in NSCLC by Region
    • Deals Landscape - Recent Mergers, Acquisitions, and Strategic Alliances in NSCLC
  • Commercial Assessment
    • Commercial Assessment - Key Market Players in NSCLC
  • Future Market Catalysts
    • Future Market Catalysts - Upcoming Market Catalysts in NSCLC
  • Appendix
    • Methodology
    • Methodology - Sales Forecasts
    • Methodology - Pricing and Reimbursement
    • Methodology - Phase Transition Success Rate and Likelihood of Approval Analysis
    • About the Authors
  • Contact Us
    • Contact Us - A Global Network of Offices

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