This report includes coverage of immuno-oncology overview, trends, value chain, leading marketed and pipeline products, market analysis, regulatory landscape and market access, opportunities, challenges, and unmet needs, commercial assessment - major current and future players in the immuno-oncology field.
The field of immuno-oncology (IO) is consolidating its presence in most major types of cancer. Checkpoint modulation to remain the most valuable IO sector. 2022–23 has seen some IO success, but no major IO breakthrough has happened. Personalized treatment using biomarkers, therapeutic options for checkpoint refractory patients, and the high cost of therapy remain as unmet needs.
Key Highlights
Forecast includes 8 countries Forecast covers 2022-2028 Seven markets are extrapolated, obtaining a 15-market value for all GBM therapeutics
Scope
This report includes disease epidemiology, a 10-year patient-based forecast for marketed and pipeline therapies with established mechanisms of action and cell & gene therapies by class, including early- to late clinical stage pipeline products with launch date assessment by 8MM market.
Reasons to Buy
OBTAIN IMMUNO-ONCOLOGY MARKET ASSESSMENT AND FORECAST ACROSS MULTIPLE REGIONS
GAIN INSIGHT INTO PROMISING EARLY STAGE APPROACHES
Our indication specific forecast models answer questions such as -
What is the target patient pool for cell & gene therapies in each cancer indication?
Which patient groups are more likely to receive these therapies?
What does the cell & gene therapy clinical stage pipeline look like in each cancer indication
What is the anticipated breakdown between autologous and allogeneic cell therapies?
When will cell & gene therapies launch in each market?
What is the total market value projected for the forecast end, in 2031?
Related Reports
Executive Summary
Immuno-oncology Overview
What Is IO?
What Is Immuno-oncology?
What Is Immuno-oncology According to Regulators
Most Important Milestones of Immuno-oncology Development Globally
Key Twitter Chat
Trends
Industry Trends - Bispecific Antibodies
Industry Trends - Cancer Vaccines
Industry Trends - Cell Therapies
Industry Trends - Checkpoint Modulators
Industry Trends - Cytokines
Industry Trends - Oncolytic Viruses
Regulatory Trends
Value Chain
Immuno-oncology Value Chain
Bispecific Antibodies
Bispecific Antibodies - KOL Perspective
Cancer Vaccines
Cancer Vaccines - KOL Perspective
Cell Therapies
Cell Therapies - KOL Perspective
Checkpoint Modulators
Checkpoint Modulators - KOL Perspective
Next-Generation Cytokines
Cytokines - KOL Perspective
Oncolytic Viruses
Oncolytic Viruses - KOL Perspective
Immuno-oncology in Clinical Trials
Marketed Products
In the Last Five Years, There Has Been an Explosion in the Number of IO Agents Receiving Approval
Total Market Size for IO Agents
10 Highest-Grossing IO Treatments in 2022
Table 10 Highest-Grossing IO Treatments in 2022
Leading Checkpoint Modulators in the 8MM
Checkpoint Modulator Treatments - KOL Perspective
Leading BiTEs in the 8MM
BiTEs - KOL Perspective
Leading Cancer Vaccines and Oncolytic Viruses in the 8MM
Cancer Vaccine or Oncolytic Virus Treatments - KOL Perspective
Leading Cell Therapies in the 8MM
Cell Therapy Treatments - KOL Perspective
Pipeline Products
IO Pipeline Products in the 8MM
Future Outlook of IO Agents, According to High-Prescribing Physicians
Consensus Forecast Sales for the Top Three Pipeline Candidates per IO Class
The Forecast Highest-Grossing Bispecific Antibody Products
Bispecific Antibody Treatments - KOL Perspective
The Forecast Highest-Grossing Vaccine Products
Cancer Vaccine Treatments - KOL Perspective
The Forecast Highest-Grossing Cell Therapy Products
Cell Therapy Treatments - KOL Perspective
The Forecast Highest-Grossing Checkpoint Modulator Products
Checkpoint Modulator Treatments - KOL Perspective
The Forecast Highest-Grossing Cytokine Products
Cytokines - KOL Perspective
The Forecast Highest-Grossing Oncolytic Virus Products
Oncolytic Virus Treatments - KOL Perspective
Market Analysis
Market Analysis and Forecast of the Six Classes of IO Agents
Top 10 Strategic Partnership Deals of the Last Decade by Size in the IO Space
Latest Strategic Partnership Deals in the IO Space
Top 10 Mergers and Acquisitions that Include IO Assets: 2018-23
Latest Mergers and Acquisitions that Include IO Assets
Regulatory and Market Access
IO in Clinical Trials
Clinical Trials
Endpoints in IO Clinical Trials - KOL Perspective
Challenges in IO Clinical Trials - KOL Perspective
Regulatory and Market Access - US
Key Market Access and Regulatory Concepts - US
Market Access - US Payer & KOL Perspective
Regulatory and Market Access - EU
Key Market Access and Regulatory Concepts - Europe
Market Access - EU Payer & KOL Perspective
Regulatory and Market Access - Japan
Key Market Access and Regulatory Concepts - Japan
Market Access - Japan KOL Perspective
Regulatory and Market Access - China
Key Market Access and Regulatory Concepts - China
Market Access - China KOL Perspective
Early Access Schemes
Barriers to Access According to High Prescribers
Opportunities, Challenges, and Unmet Needs
Bispecific Antibodies
Bispecific Antibodies - Additional KOL Perspective
Cancer Vaccines
Cancer Vaccines - Additional KOL Perspective
Cell Therapies
Cell Therapies - Additional KOL Perspective
Checkpoint Modulators
Checkpoint Modulators - Additional KOL Perspective
Cytokines
Cytokines - Additional KOL Perspective
Oncolytic Viruses
Oncolytic Viruses - Additional KOL Perspective
Clinical Unmet Needs in IO - Gap Analysis
Commercial Unmet Needs in Immuno-oncology - Gap Analysis
Unmet Needs - KOL Perspective
Unmet Needs According to High Prescribers
R&D Strategies
Opportunities for the Industry - Modern Approaches & Collaboration
Closing Remarks - In Their Words
Companies
Drug Development Scorecard - IO
Current Major Players - Novartis
Current Major Players - Merck & Co.
Current Major Players - Gilead Sciences
Current Major Players - Roche
Current Major Players - BMS
Current Major Players - AstraZeneca
Current Major Players - Sanofi
Current Major Players - Amgen
Current Major Players - Dendreon Pharmaceuticals
Current Major Players - Legend Biotech
Current Major Players - Johnson & Johnson
Current Major Players - Daiichi-Sankyo
Current Major Players - Kite
Current Major Players - Regeneron
Future Players Based on Pipeline Strength - Genmab
Future Players Based on Pipeline Strength - Iovance Therapeutics
Future Players Based on Pipeline Strength - Replimune
Future Players Based on Pipeline Strength - VBI Vaccines
Future Players Based on Pipeline Strength - Jounce Therapeutics (Acquired by Concentra Biosciences)
Future Players Based on Pipeline Strength - OncoSec
Future Players Based on Pipeline Strength - AbbVie
Future Players Based on Pipeline Strength - BioNTech
Future Players Based on Pipeline Strength - Greenwich LifeSciences
Future Players Based on Pipeline Strength - CRISPR Therapeutics
Future Players Based on Pipeline Strength - Allogene Therapeutics
Future Players Based on Pipeline Strength - Xilio Therapeutics
Future Players Based on Pipeline Strength - Candel Therapeutics