Glucagon-Like Peptide 1 Receptor (GLP-1R) Agonists in Type 2 Diabetes and Obesity: Seven-Market Drug Forecast and Market Analysis

Glucagon-Like Peptide 1 Receptor (GLP-1R) Agonists in Type 2 Diabetes and Obesity: Seven-Market Drug Forecast and Market Analysis


Summary

This report covers the 7MM (US, France, Germany, Italy, Spain, UK, Japan) and provides an Excel-based forecast model for the Glucagon-Like Peptide 1 Receptor (GLP-1R) Agonists in Type 2 Diabetes and Obesity market through 2033.
  • The use of GLP-1R agonists is expected to quadruple in the next 10 years, at a CAGR of 14.9%. The GLP-1R agonists market across the 7MM was valued at $31.3 billion in 2023, and it is projected to reach $125.3 billion by 2033. At present, GLP-1R agonists are approved for type 2 diabetes and obesity. They can be used as second-line therapies if metformin pharmacotherapy is not enough in type 2 diabetes management, and after lifestyle modifications have not been effective in reducing weight in obesity patients. The GLP-1R agonists marketed for type 2 diabetes are Ozempic (semaglutide), Rybelsus (semaglutide), Trulicity (dulaglutide), Victoza (liraglutide), Mounjaro (tirzepatide), Xultophy (liraglutide + insulin), Suliqua (lixisenatide + insulin), Bydureon (exenatide), Byetta (exenatide), and Lyxumia (lixisenatide)
  • The GLP-1R agonists marketed for obesity are Saxenda (liraglutide), Wegovy (semaglutide), and Mounjaro/Zepbound (tirzepatide).
  • The major unmet needs in the GLP-1R agonist space currently are costs, long-term adherence and tolerability, drug availability, and physician awareness.
  • There are multiple GLP-1R agonist-based therapies in late-stage clinical development for type 2 diabetes or obesity, including combination therapies and novel dual and triple agonists.
  • The major market driver in the 7MM will be the increased patient population and increased awareness of and confidence in this relatively new drug class.
Key Highlights
  • Report deliverables include a Pdf and Excel-based forecast model. Forecast includes US, 5EU, and Japan.
  • Forecast covers the period 2023-2033.
  • 2023 base year sales within the GLP-1R agonists market are approximately $31.3billion across the 7MM detailed in this report. GlobalData estimates that the GLP-1R agonist market will grow at a compound annual growth rate (CAGR) of 14.9% to reach $125 billion by the end of the forecast period.
Scope
  • Overview of GLP-1R agonists, type 2 diabetes and obesity, including epidemiology, symptoms, diagnosis, and disease management.
  • Annualized GLP-1R agonists therapeutics market revenue, cost of therapy per patient, and treatment usage patterns forecast from 2023 to 2033.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications of these factors for the GLP-1R agonists market.
  • Pipeline analysis: comprehensive data assessing emerging trends and dual/triple mechanisms of action under development for tye 2 diabetes and obesity medicines with a GLP-1R agonist action. The most promising candidates in late-stage development are profiled.
  • Analysis of the current and future market competition in the 7MM GLP-1R agonists therapeutics type 2 diabetes and obesity market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
Reasons to Buy
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the 7MM GLP-1R agonists therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the 7MM GLP-1R agonists therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
Please Note:this is delivered as a zipfile.


1. Cover Page
1.1. Contents
1.2. Abbreviations
1.3. Related Reports
2. Executive Summary
3. Disease Overview
3.1. Overview of Type 2 Diabetes
3.2. Overview of Obesity
4. Overview of GLP-1R Agonists
4.1. Overview of GLP-1R Agonists
4.2. GLP-1R Agonists SWOT Analysis in the Type 2 Diabetes and Obesity Market
4.3. Classification of GLP-1R Agonist-Treated Patients
5. Epidemiology
5.1. Diagnosed Prevalent Cases of Type 2 Diabetes, Men and Women, 2023-33
5.2. Diagnosed Prevalent Cases of Type 2 Diabetes by BMI Class, Men and Women, All Ages, 2023
5.3. Diagnosed Prevalent Cases of Obesity and Overweight, Men and Women, Ages ≥5 Years, 2023-33
5.4. Diagnosed Prevalent Cases of Obesity and Overweight, Men and Women, Ages ≥5 Years, 2023
5.5. Diagnosed Prevalent Cases of Obesity and Overweight Without Type 2 Diabetes, Men and Women, Ages ≥5 Years, 2023
5.6. Sources and Methodology for Diagnosed Prevalent Cases of Type 2 Diabetes
5.7. Sources and Methodology for Diagnosed Prevalent Cases of Type 2 Diabetes by BMI Class
5.8. Sources and Methodology for Diagnosed Prevalent Cases of Obesity and Overweight
5.9. Sources and Methodology for Diagnosed Prevalent Cases of Obesity and Overweight by Type 2 Diabetes Diagnosis
5.10. Sources and Methodology - Diagnosed Prevalence of Type 2 Diabetes
5.11. Sources and Methodolody - Diagnosed Prevalence of Type 2 Diabetes by BMI Class
5.12. Sources and Methodology - Diagnosed Prevalence of Obesity and Overweight
5.13. Sources and Methodology - Diagnosed Prevalence of Obesity and Overweight by Type 2 Diabetes Diagnosis
6. Current GLP-1R Agonists on the Market
6.1. Treatment Paradigm - Type 2 Diabetes
6.2. Treatment Paradigm - Obesity
6.3. Treatment Paradigm: KOL Perspective
6.4. GLP-1R Agonists Market Access in the 7MM
6.5. Current GLP-1R Agonists on the Market for Type 2 Diabetes and Obesity
6.6. Current Treatment Options: KOL Perspective
6.7. Product Profile of Ozempic (semaglutide)
6.8. Product Profile of Rybelsus (semaglutide
6.9. Product Profile of Trulicity (dulaglutide)
6.10. Product Profile of Victoza (liraglutide)
6.11. Product Profile of Xultophy (liraglutide + insulin degludec)
6.12. Product Profile of Mounjaro/ Zepbound (tirzepatide)
6.13. Product Profile of Bydureon (exenatide)
6.14. Product Profile of Suliqua (lixisenatide + insulin glargine)
6.15. Wegovy (semaglutide)
6.16. Saxenda (liraglutide)
7. Unmet Needs and Opportunities
7.1. Unmet Needs in the GLP-1R Agonists Space
7.2. Cost of Therapy
7.3. Long-Term Adherence
7.4. Therapy Availability
7.5. Physicians Awareness
8. R&D Strategies
8.1. Trends in Clinical Trial Design in GLP-1R Agonists Space
8.2. Trends in Deal-Making of GLP-1R Agonists in the Type 2 Diabetes and Obesity Market
9. Pipeline Assessment
9.1. GLP-1R Agonists Type 2 Diabetes and Obesity Pipeline Overview
9.2. Late-Stage GLP-1R Agonists Pipeline Agents for Type 2 Diabetes and Obesity
9.3. Product Profile of Novo Nordisk’s CagriSema (cagrilintide + semaglutide)
9.4. Product Profile of Novo Nordisk’s IcoSema (insulin icodec + semaglutide)
9.5. Product Profile of Eli Lilly’s Orforglipron calcium
9.6. Product Profile of Eli Lilly’s Retatrutide
9.7. Product Profile of Boerhinger Ingelheim’s Survodutide
9.8. Product Profile of liraglutide biosimilars
9.9. Product Profile of Novo Nordisk’s NN-9932 (oral semaglutide)
9.10. GLP-1R Agonists: Clinical Trials Overview
10. Market Outlook
10.1. GLP-1R Agonists in Type 2 Diabetes and Obesity Market Forecast
10.2. GLP-1R Agonists Sales by Indication and Drug, 2023-33
10.3. GLP-1R Agonists Market Forecast, 2023 Drug Sales by Indication
10.4. GLP-1R Agonists Market Forecast, 2033 Drug Sales by Indication
10.5. Market Drivers and Barriers
11. Appendix
11.1. Primary Research - KOL Information
11.2. Bibliography
11.3. About the Authors
12. Contact Us

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