Diabetic Nephropathy (DN) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

Diabetic Nephropathy (DN) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape


Summary

This reports provides a data-driven overview of the current and future competitive landscape in DN therapeutics.
  • More than 16 million diagnosed prevalent cases of DN are anticipated in 2023 in the 16 countries covered in GlobalData’s epidemiology forecast for DN.
  • Among the marketed DN drugs available, most of the drugs are enzyme inhibitors, followed by receptor antagonists, by mechanism of action.
  • The DN pipeline consists of over 95 drugs spanning all stages of development (discovery to late-stage clinical development), with only 4.2% of drugs present in Phase III.
  • Of the 441 trials initiated in DN the past 10 years, 286 trials have been completed, while 100 trials are currently ongoing.
  • Partnerships were the most prominent type of deal ventured in the DN space globally.
Scope

GlobalData’s DN: Competitive Landscape combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include -
  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Annual Therapy Cost
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts
Reasons to Buy
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the DN market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global DN market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.


  • Key Findings
  • Disease Overview
    • Disease Etiology Disease Overview
  • Epidemiology Overview
    • Epidemiology Overview – Diagnosed Prevalent Cases of DN in 2023 and 2028
  • Treatment Overview
    • Treatment Guidelines
    • Treatment Algorithm
  • Marketed Drugs Assessment
    • Marketed Drugs – Leading Marketed Drugs in DN
    • Marketed Drugs – Overview by Mechanism of Action
    • Marketed Drugs – Overview by Route of Administration
    • Marketed Drugs – Overview by Molecule Type
    • Marketed Drugs Profile: Mitsubishi Tanabe Pharma's Canaglu/Invokana
    • Marketed Drugs Profile: Sanofi's Aprovel/Karvea/Avapro
    • Marketed Drugs Profile: Organon's Cozaar/Nu-Lotan/Lortaan
  • Pricing and Reimbursement Assessment
    • Marketed Drugs – Manufacturer Price per mg
    • Marketed Drugs – Time to Pricing and Reimbursement for Triatec
  • Pipeline Drugs Assessment
    • Pipeline Drugs Overview – Mid-to-Late-Stage Pipeline Drugs in DN
    • Pipeline Drugs – Overview by Development Stage
    • Pipeline Drugs – Overview by Mechanism of Action
    • Pipeline Drugs – Overview by Route of Administration
    • Pipeline Drugs – Overview by Molecule Type
    • Pipeline Drugs – Phase Transition Success Rate and Likelihood of Approval in DN
    • Pipeline Drugs – Phase Transition Success Rate and Likelihood of Approval in Metabolic Disorders and DN
  • Clinical Trials Assessment
    • Clinical Trials in DN – Historical Overview
    • Clinical Trials in DN – Overview by Phase
    • Clinical Trials in DN – Overview by Status
    • Clinical Trials in DN – Overview by Phase for Ongoing and Planned Trials
    • Clinical Trials in DN – Trials with a Virtual Component
    • Clinical Trials in DN – Geographic Overview
    • Clinical Trials in DN – Single-Country and Multinational Trials by Region
    • Clinical Trials in DN – Top Sponsors with Breakdown by Phase
    • Clinical Trials in DN – Top Sponsors with Breakdown by Status
    • Clinical Trials in DN – Overview by Endpoint Status
    • Clinical Trials in DN – Overview by Race and Ethnicity
    • Clinical Trials in DN – Enrollment Data
      • Table Enrollment data for Phase II trials in DN (including Phase II and II/III)
      • Table Enrollment data for Phase III trials in DN (including Phase III and III/IV)
    • Clinical Trials in DN – Overview of Sites by Geography
    • Clinical Trials in DN – Top 20 Countries for Trial Sites
    • Clinical Trials in DN – Top 20 Sites Globally
    • Clinical Trials – Feasibility Analysis: Geography Overview
    • Clinical Trials – Feasibility Analysis: Benchmark Models for DN
  • Deals Landscape
    • Deals Landscape – Mergers, Acquisitions, and Strategic Alliances in DN by Region
    • Deals Landscape – Recent Mergers, Acquisitions, and Strategic Alliances in DN
  • Commercial Assessment
    • Commercial Assessment – Key Market Players in DN
  • Future Market Catalysts
    • Future Market Catalysts – Upcoming Market Catalysts in DN
  • Appendix
    • Methodology
    • Methodology – Sales Forecasts
    • Methodology – Pricing and Reimbursement
    • Methodology – Phase Transition Success Rate and Likelihood of Approval Analysis
    • About the Authors
  • Contact us
    • Contact Us – A Global Network of Offices
    • About GlobalData

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