Alzheimer’s Disease: Eight-Market Drug Forecast and Market Analysis

Alzheimer’s Disease: Eight-Market Drug Forecast and Market Analysis

Summary

This report covers the 8 major markets and provides an Excel-based forecast model for the Alzheimer’s Disease market through 2033.

GlobalData estimates that the value of the Alzheimer’s Disease (AD) market in the 8MM in 2023 was $2.4 billion. This market is defined as sales of symptamatic and disease modifying (DMT) treatments including approval of anti-Aβmonoclonal antibodies (mAbs) across the 8MM (US, France, Germany, Italy, Spain, UK, Japan and China). The US and China markets make up the majority of total global sales, contributing $1.1 billion (44.7%) and $915.2 million (38.8%), respectively. The smallest market is France, contributing only 1.1% to total global sales, due to the lower AD prevalent population in the country, as well as the lack of reimbursement of the current AD symptomatic therapies resulting in lower treatment rates in France.By the end of the forecast period in 2033, GlobalData projects AD sales to rise to $19.3 billion in the 8MM, at a compound annual growth rate (CAGR) of 23.4%.

Scope

  • Overview of Alzheimer’s Disease, including epidemiology, symptoms, diagnosis, and disease management.
  • Annualized Alzheimer’s Disease therapeutics market revenue, cost of therapy per patient, and treatment usage patterns forecast from 2023 to 2033.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications of these factors for the migraine therapeutics market.
  • Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for migraine treatment. The most promising candidates in late-stage development are profiled.
  • Analysis of the current and future market competition in the global Alzheimer’s Disease therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
Reasons to Buy
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the 8MM Alzheimer’s Disease therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the 8MM Alzheimer’s Disease therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
Please Note: this is delivered as a zip file.


Table of Contents
List of Tables
List of Figures
1 Alzheimer’s Disease: Executive Summary
1.1 Alzheimer’s market forecast to see double-digit sales growth out to 2033
1.2 Eisai, Biogen, and Lilly are forecast to lead the AD market in 2033
1.3 Opportunities to fulfil key unmet needs will remain
1.4 Novel late-stage pipeline drugs will be a key driver of growth
1.5 What Do Physicians Think?
2 Introduction
2.1 Catalyst
2.2 Related reports
2.3 Upcoming reports
3 Disease Overview
3.1 Etiology
3.1.1 Risk genes
3.1.2 Deterministic genes
3.1.3 Protective genes
3.1.4 Metabolic disruption
3.2 Pathophysiology
3.2.1 Structural changes in the brain
3.2.2 Degenerative process
3.2.3 Aβ plaques
3.2.4 Neurofibrillary tangles
3.2.5 Neurotransmitter deficiencies
3.2.6 Oxidative stress
3.3 Biomarkers / targets of interest
3.4 Disease staging systems
3.5 Symptoms and prognosis
4 Epidemiology
4.1 Disease Background
4.2 Risk Factors and Comorbidities
4.3 Global and Historical Trends
4.4 Forecast Methodology
4.4.1 Sources
4.4.2 Forecast Assumptions and Methods
4.4.3 Forecast assumptions and methods: total prevalent cases of AD by DSM-IV criteria
4.4.4 Forecast assumptions and methods: total prevalent cases of AD by severity
4.4.5 Forecast assumptions and methods: total prevalent cases of preclinical AD
4.4.6 Forecast assumptions and methods: total prevalent cases of MCI
4.5 Epidemiological Forecast for AD (2023-33)
4.5.1 Total prevalent cases of AD by DSM-IV criteria
4.5.2 Age-specific total prevalent cases of AD by DSM-IV criteria
4.5.3 Sex-specific total prevalent cases of AD by DSM-IV criteria
4.5.4 Total prevalent cases of AD by severity
4.5.5 Total prevalent cases of preclinical AD
4.5.6 Age-specific total prevalent cases of preclinical AD
4.5.7 Sex-specific total prevalent cases of preclinical AD
4.5.8 Total prevalent cases of MCI
4.5.9 Age-specific total prevalent cases of MCI
4.5.10 Sex-specific total prevalent cases of MCI
4.6 Discussion
4.6.1 Epidemiological forecast insight
4.6.2 COVID-19 impact
4.6.3 Limitations of the Analysis
4.6.4 Strengths of the Analysis
5 Disease Management
5.1 Diagnosis and treatment overview
5.2 KOL insights on disease management
6 Current Treatment Options
6.1 Overview
7 Unmet Needs and Opportunity Assessment
7.1 Overview
7.2 More efficacious DMTs
7.3 Improved control of behavioral symptoms
7.4 Symptomatic drugs for cognition
7.5 Improving diagnosis earlier in the disease progression
7.6 Access to treatment
8 R&D Strategies
8.1 Overview
8.1.1 Targeting Aβ
8.1.2 Novel MOAs
8.1.3 Targeting agitation and psychosis
8.1.4 Targeting preclinical AD
8.1.5 Combination therapies
8.1.6 Non-pharmacological treatments
8.2 Clinical Trials Design
8.2.1 Inclusion/exclusion criteria
8.2.2 Endpoints
8.2.3 Use of biomarkers in trial design
9 Pipeline Assessment
9.1 Overview
9.2 Promising drugs in clinical development
10 Pipeline Valuation Analysis
10.1 Overview
10.2 Competitive Assessment
10.2.1 Potential DMTs
10.2.2 Therapies for agitation and psychosis associated with AD
11 Current and Future Players
11.1 Overview
11.2 Deal-Making Trends
12 Market Outlook
12.1 Global Markets
12.1.1 Forecast
12.1.2 Drivers and barriers - global issues
12.2 US
12.2.1 Forecast
12.2.2 Key Events
12.2.3 Drivers and Barriers
12.3 5EU
12.3.1 Forecast
12.3.2 Key Events
12.3.3 Drivers and Barriers
12.4 Japan
12.4.1 Forecast
12.4.2 Key events
12.4.3 Drivers and barriers
12.5 China
12.5.1 Forecast
12.5.2 Key events
12.5.3 Drivers and barriers
13 Appendix
13.1 Bibliography
13.2 Abbreviations
13.3 AD clinical development pipeline
13.4 Methodology
13.4.1 Forecasting methodology
13.5 Primary research - KOLs interviewed for this report
13.6 Primary research - prescriber survey
13.7 About the authors
13.7.1 Analyst
13.7.2 Therapy Area Director
13.7.3 Epidemiologist
13.7.4 Managing Epidemiologist
13.7.5 Vice President of Disease Intelligence and Epidemiology
13.7.6 Global Head of Pharma Research, Analysis, and Competitive Intelligence
About GlobalData
Contact Us

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook
Cookie Settings