Uveal Melanoma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Uveal Melanoma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Uveal Melanoma – Drugs In Development, 2022, provides an overview of the Uveal Melanoma (Oncology) pipeline landscape.

Uveal melanoma, the most common intraocular tumor, is a disease in which cancer (malignant) cells are found in the part of the eye called the uvea. The uvea contains cells called melanocytes. When these cells become cancerous, the cancer is called a melanoma. Symptoms include dark spot on the iris, glaucoma, eye pain and eye redness. Uveal melanoma is more common in people who have atypical mole syndrome, dysplastic nevus syndrome, and ocular or oculodermal melanocytosis. Treatment includes surgery, radiation and proton therapy.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Uveal Melanoma – Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Uveal Melanoma (Oncology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Uveal Melanoma (Oncology) pipeline guide also reviews of key players involved in therapeutic development for Uveal Melanoma and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 1, 29, 12, 1, 23, 1 and 1 respectively. Similarly, the Universities portfolio in Phase III, Phase II, Phase I and Preclinical stages comprises 1, 3, 2 and 1 molecules, respectively.

Uveal Melanoma (Oncology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Uveal Melanoma (Oncology).
  • The pipeline guide reviews pipeline therapeutics for Uveal Melanoma (Oncology) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Uveal Melanoma (Oncology) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Uveal Melanoma (Oncology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Uveal Melanoma (Oncology)
Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Uveal Melanoma (Oncology).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Uveal Melanoma (Oncology) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


Introduction
Global Markets Direct Report Coverage
Uveal Melanoma – Overview
Uveal Melanoma – Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Uveal Melanoma – Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Uveal Melanoma – Companies Involved in Therapeutics Development
A6 Pharmaceuticals LLC
Acrotech Biopharma LLC
Adagene Suzhou Ltd
Aeglea BioTherapeutics Inc
Alpine Immune Sciences Inc
Astellas Pharma Inc
Astex Pharmaceuticals Inc
Aura Biosciences Inc
Bellicum Pharmaceuticals Inc
Biogazelle NV
BioMed Valley Discoveries Inc
Bristol-Myers Squibb Co
Byondis BV
Codiak BioSciences Inc
Delcath Systems Inc
Dompe Farmaceutici SpA
Exelixis Inc
F. Hoffmann-La Roche Ltd
Faron Pharmaceuticals Oy
Foghorn Therapeutics Inc
Fusion Pharmaceuticals Inc
GSK plc
Hillstream BioPharma Inc
Ideaya Biosciences Inc
Immunocore Holdings Plc
Immunocore Limited
Inventiva SA
InxMed (Beijing) Co Ltd
iOnctura SA
Kezar Life Sciences Inc
Kymera Therapeutics Inc
Kyorin Pharmaceutical Co Ltd
Linnaeus Therapeutics Inc
Lyvgen Biopharma Ltd
Merck & Co Inc
Mereo Biopharma Group Plc
Modulation Therapeutics Inc
Novartis AG
Okogen Inc
Oncomatryx Biopharma SL
OncoSpherix Inc
Ono Pharmaceutical Co Ltd
Oxular Ltd
Pfizer Inc
Plexxikon Inc
Prelude Therapeutics Inc
Provectus Biopharmaceuticals Inc
Regeneron Pharmaceuticals Inc
Replimune Ltd
Rubius Therapeutics Inc
Sapience Therapeutics Inc
Seagen Inc
Statera Biopharma Inc
TriSalus Life Sciences Inc
Vanquish Oncology Inc
Verastem Inc
WPD Pharmaceuticals Inc
Uveal Melanoma – Drug Profiles
(nivolumab + relatlimab) – Drug Profile
ADG-126 – Drug Profile
Alocelyvir – Drug Profile
Antisense Oligonucleotides for Oncology – Drug Profile
belinostat – Drug Profile
belzupacap sarotalocan – Drug Profile
bexmarilimab – Drug Profile
binimetinib – Drug Profile
BPX-701 – Drug Profile
cabozantinib s-malate – Drug Profile
Cell Therapy for Metastatic Uveal Melanoma – Drug Profile
Cell Therapy to Target GP100 for Melanoma and Non Small Cell Lung Cancer – Drug Profile
Cellular Immunotherapy for Solid Tumors – Drug Profile
Cellular Immunotherapy to Target Melan-A, MAGE-3 and Survivin for Melanoma and Uveal Melanoma – Drug Profile
crizotinib – Drug Profile
darovasertib – Drug Profile
davoceticept – Drug Profile
defactinib hydrochloride – Drug Profile
Drugs for Uveal Melanoma – Drug Profile
DYP-688 – Drug Profile
entolimod – Drug Profile
entrectinib – Drug Profile
etigilimab – Drug Profile
exoASO-STAT6 – Drug Profile
FHD-286 – Drug Profile
FPI-1434 – Drug Profile
gebasaxturev – Drug Profile
Gene Therapy to Target MAGE-C2 for Oncology – Drug Profile
ibudilast – Drug Profile
IMCF-106C – Drug Profile
IN-10018 – Drug Profile
IOA-244 – Drug Profile
ipilimumab – Drug Profile
ipilimumab + nivolumab – Drug Profile
KCN-1 – Drug Profile
KT-253 – Drug Profile
KZR-261 – Drug Profile
ladarixin – Drug Profile
LNS-8801 – Drug Profile
LVGN-6051 – Drug Profile
LVGN-7409 – Drug Profile
melphalan hydrochloride – Drug Profile
MTI-201 – Drug Profile
NAV-2729 – Drug Profile
niraparib – Drug Profile
nivolumab – Drug Profile
OMTX-703 – Drug Profile
OXU-004 SR – Drug Profile
OXU-005 – Drug Profile
PAC-1 – Drug Profile
pegzilarginase – Drug Profile
PLX-2853 – Drug Profile
PRT-811 – Drug Profile
PV-10 – Drug Profile
RP-2 – Drug Profile
RTX-240 – Drug Profile
salinomycin – Drug Profile
SD-101 – Drug Profile
SEA-CD40 – Drug Profile
Small Molecule for Uveal Melanoma – Drug Profile
Small Molecule to Inhibit HIF-1 and HIF-2 for Uveal Melanoma – Drug Profile
sotrastaurin acetate – Drug Profile
SSI-361 – Drug Profile
ST-101 – Drug Profile
sunitinib malate – Drug Profile
SYD-3521 – Drug Profile
tebentafusp – Drug Profile
ulixertinib – Drug Profile
Vaccine for Oncology – Drug Profile
VS-6766 – Drug Profile
WPD-102 – Drug Profile
Yap-Tead – Drug Profile
YM-254890 – Drug Profile
ziv-aflibercept – Drug Profile
Uveal Melanoma – Dormant Projects
Uveal Melanoma – Discontinued Products
Uveal Melanoma – Product Development Milestones
Featured News & Press Releases
Jun 08, 2022: Medison Pharma announces the approvals by Health Canada and Therapeutics Goods Administration of KIMMTRAK (tebentafusp) for the treatment of unresectable or metastatic uveal melanoma
Jun 07, 2022: Provectus Biopharmaceuticals announces acceptance of PV-10 immunotherapy abstract for metastatic uveal melanoma at American Society of Clinical Oncology (ASCO) 2022 Annual Meeting
Jun 07, 2022: Immunocore announces upcoming presentations at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting
Jun 07, 2022: iOnctura to present at ASCO encouraging phase Ib refractory uveal melanoma data for first semi-allosteric PI3Kd inhibitor, IOA-244
Jun 06, 2022: Positive initial results from CHOPIN Phase 1b Trial, FOCUS trial update and QoL Study presented at the 2022 ASCO Annual Meeting
Jun 06, 2022: Immunocore presents new data on KIMMTRAK (tebentafusp-tebn) in metastatic cutaneous (mCM) and uveal melanoma (mUM) at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting
May 27, 2022: iOnctura to present at ASCO IOA-244 showing highly promising impact on overall survival for patients with metastatic and refractory uveal melanoma
May 02, 2022: IDEAYA Biosciences receives Orphan Drug Designation for Darovasertib, a PKC Inhibitor, for the treatment of Uveal Melanoma
Apr 20, 2022: MediciNova announces publication of MN-166 (ibudilast) data regarding prevention of metastasis in uveal melanoma in Molecular Cancer Research
Apr 13, 2022: Foghorn Therapeutics presents new preclinical data on novel BRG1/BRM inhibitor FHD-286 at the 2022 AACR Annual Meeting
Apr 04, 2022: European Commission approves KIMMTRAK (tebentafusp) for the treatment of unresectable or metastatic uveal melanoma
Apr 01, 2022: Foghorn Therapeutics to present preclinical data for FHD-286 at the 2022 AACR Annual Meeting
Mar 21, 2022: Aura Biosciences announces orphan drug designation granted to AU-011 by European Commission for the treatment of uveal melanoma (includes choroidal melanoma)
Mar 02, 2022: Hillstream BioPharma R&D day highlights ferroptosis, the non-genetic novel, emerging mechanism of action, targeting drug resistant and devastating cancers
Feb 26, 2022: Provectus Biopharmaceuticals announces acceptance of PV-10 metastatic uveal melanoma abstract for oral presentation at 2022 International Society of Ocular Oncology (ISOO) Congress
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Table 1: Number of Products under Development for Uveal Melanoma, 2022
Table 2: Number of Products under Development by Companies, 2022
Table 3: Number of Products under Development by Companies, 2022 (Contd..1)
Table 4: Number of Products under Development by Companies, 2022 (Contd..2)
Table 5: Number of Products under Development by Universities/Institutes, 2022
Table 6: Products under Development by Companies, 2022
Table 7: Products under Development by Companies, 2022 (Contd..1)
Table 8: Products under Development by Companies, 2022 (Contd..2)
Table 9: Products under Development by Companies, 2022 (Contd..3)
Table 10: Products under Development by Universities/Institutes, 2022
Table 11: Number of Products by Stage and Target, 2022
Table 12: Number of Products by Stage and Target, 2022 (Contd..1)
Table 13: Number of Products by Stage and Target, 2022 (Contd..2)
Table 14: Number of Products by Stage and Mechanism of Action, 2022
Table 15: Number of Products by Stage and Mechanism of Action, 2022 (Contd..1)
Table 16: Number of Products by Stage and Mechanism of Action, 2022 (Contd..2)
Table 17: Number of Products by Stage and Route of Administration, 2022
Table 18: Number of Products by Stage and Molecule Type, 2022
Table 19: Uveal Melanoma – Pipeline by A6 Pharmaceuticals LLC, 2022
Table 20: Uveal Melanoma – Pipeline by Acrotech Biopharma LLC, 2022
Table 21: Uveal Melanoma – Pipeline by Adagene Suzhou Ltd, 2022
Table 22: Uveal Melanoma – Pipeline by Aeglea BioTherapeutics Inc, 2022
Table 23: Uveal Melanoma – Pipeline by Alpine Immune Sciences Inc, 2022
Table 24: Uveal Melanoma – Pipeline by Astellas Pharma Inc, 2022
Table 25: Uveal Melanoma – Pipeline by Astex Pharmaceuticals Inc, 2022
Table 26: Uveal Melanoma – Pipeline by Aura Biosciences Inc, 2022
Table 27: Uveal Melanoma – Pipeline by Bellicum Pharmaceuticals Inc, 2022
Table 28: Uveal Melanoma – Pipeline by Biogazelle NV, 2022
Table 29: Uveal Melanoma – Pipeline by BioMed Valley Discoveries Inc, 2022
Table 30: Uveal Melanoma – Pipeline by Bristol-Myers Squibb Co, 2022
Table 31: Uveal Melanoma – Pipeline by Byondis BV, 2022
Table 32: Uveal Melanoma – Pipeline by Codiak BioSciences Inc, 2022
Table 33: Uveal Melanoma – Pipeline by Delcath Systems Inc, 2022
Table 34: Uveal Melanoma – Pipeline by Dompe Farmaceutici SpA, 2022
Table 35: Uveal Melanoma – Pipeline by Exelixis Inc, 2022
Table 36: Uveal Melanoma – Pipeline by F. Hoffmann-La Roche Ltd, 2022
Table 37: Uveal Melanoma – Pipeline by Faron Pharmaceuticals Oy, 2022
Table 38: Uveal Melanoma – Pipeline by Foghorn Therapeutics Inc, 2022
Table 39: Uveal Melanoma – Pipeline by Fusion Pharmaceuticals Inc, 2022
Table 40: Uveal Melanoma – Pipeline by GSK plc, 2022
Table 41: Uveal Melanoma – Pipeline by Hillstream BioPharma Inc, 2022
Table 42: Uveal Melanoma – Pipeline by Ideaya Biosciences Inc, 2022
Table 43: Uveal Melanoma – Pipeline by Immunocore Holdings Plc, 2022
Table 44: Uveal Melanoma – Pipeline by Immunocore Limited, 2022
Table 45: Uveal Melanoma – Pipeline by Inventiva SA, 2022
Table 46: Uveal Melanoma – Pipeline by InxMed (Beijing) Co Ltd, 2022
Table 47: Uveal Melanoma – Pipeline by iOnctura SA, 2022
Table 48: Uveal Melanoma – Pipeline by Kezar Life Sciences Inc, 2022
Table 49: Uveal Melanoma – Pipeline by Kymera Therapeutics Inc, 2022
Table 50: Uveal Melanoma – Pipeline by Kyorin Pharmaceutical Co Ltd, 2022
Table 51: Uveal Melanoma – Pipeline by Linnaeus Therapeutics Inc, 2022
Table 52: Uveal Melanoma – Pipeline by Lyvgen Biopharma Ltd, 2022
Table 53: Uveal Melanoma – Pipeline by Merck & Co Inc, 2022
Table 54: Uveal Melanoma – Pipeline by Mereo Biopharma Group Plc, 2022
Table 55: Uveal Melanoma – Pipeline by Modulation Therapeutics Inc, 2022
Table 56: Uveal Melanoma – Pipeline by Novartis AG, 2022
Table 57: Uveal Melanoma – Pipeline by Okogen Inc, 2022
Table 58: Uveal Melanoma – Pipeline by Oncomatryx Biopharma SL, 2022
Table 59: Uveal Melanoma – Pipeline by OncoSpherix Inc, 2022
Table 60: Uveal Melanoma – Pipeline by Ono Pharmaceutical Co Ltd, 2022
Table 61: Uveal Melanoma – Pipeline by Oxular Ltd, 2022
Table 62: Uveal Melanoma – Pipeline by Pfizer Inc, 2022
Table 63: Uveal Melanoma – Pipeline by Plexxikon Inc, 2022
Table 64: Uveal Melanoma – Pipeline by Prelude Therapeutics Inc, 2022
Table 65: Uveal Melanoma – Pipeline by Provectus Biopharmaceuticals Inc, 2022
Table 66: Uveal Melanoma – Pipeline by Regeneron Pharmaceuticals Inc, 2022
Table 67: Uveal Melanoma – Pipeline by Replimune Ltd, 2022
Table 68: Uveal Melanoma – Pipeline by Rubius Therapeutics Inc, 2022
Table 69: Uveal Melanoma – Pipeline by Sapience Therapeutics Inc, 2022
Table 70: Uveal Melanoma – Pipeline by Seagen Inc, 2022
Table 71: Uveal Melanoma – Pipeline by Statera Biopharma Inc, 2022
Table 72: Uveal Melanoma – Pipeline by TriSalus Life Sciences Inc, 2022
Table 73: Uveal Melanoma – Pipeline by Vanquish Oncology Inc, 2022
Table 74: Uveal Melanoma – Pipeline by Verastem Inc, 2022
Table 75: Uveal Melanoma – Pipeline by WPD Pharmaceuticals Inc, 2022
Table 76: Uveal Melanoma – Dormant Projects, 2022
Table 77: Uveal Melanoma – Dormant Projects, 2022 (Contd..1)
Table 78: Uveal Melanoma – Discontinued Products, 2022
List of Figures
Figure 1: Number of Products under Development for Uveal Melanoma, 2022
Figure 2: Number of Products under Development by Companies, 2022
Figure 3: Number of Products under Development by Universities/Institutes, 2022
Figure 4: Number of Products by Top 10 Targets, 2022
Figure 5: Number of Products by Stage and Top 10 Targets, 2022
Figure 6: Number of Products by Top 10 Mechanism of Actions, 2022
Figure 7: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Figure 8: Number of Products by Top 10 Routes of Administration, 2022
Figure 9: Number of Products by Stage and Top 10 Routes of Administration, 2022
Figure 10: Number of Products by Top 10 Molecule Types, 2022
Figure 11: Number of Products by Stage and Top 10 Molecule Types, 2022

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