Migraine Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Migraine Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Migraine - Drugs In Development, 2022, provides an overview of the Migraine (Central Nervous System) pipeline landscape.

Migraine is a disorder characterized by repeated attacks of severe headache. A migraine headache causes throbbing or pulsating pain, usually on only one side of the head. These headaches are often associated with nausea, vomiting, and extreme sensitivity to light and sound. Symptoms include problems speaking, tingling in face, arms, and shoulders, pain behind one of the eyes and pain that gets worse with routine physical activity.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Migraine - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Migraine (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Migraine (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Migraine and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 4, 3, 11, 18, 11, 2, 32, 6 and 5 respectively. Similarly, the Universities portfolio in Phase II, Phase I and Preclinical stages comprises 1, 1 and 3 molecules, respectively.

Migraine (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Migraine (Central Nervous System).
  • The pipeline guide reviews pipeline therapeutics for Migraine (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Migraine (Central Nervous System) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Migraine (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Migraine (Central Nervous System)
Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Migraine (Central Nervous System).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Migraine (Central Nervous System) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


Introduction
Global Markets Direct Report Coverage
Migraine – Overview
Migraine – Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Migraine – Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Migraine – Companies Involved in Therapeutics Development
4P Therapeutics LLC
AbbVie Inc
Acadia Pharmaceuticals Inc
Achelios Therapeutics Inc
Acherx LLC
AEON Biopharma Inc
AgoneX Biopharmaceuticals Inc
Allodynic Therapeutics LLC
Amgen Inc
Amneal Pharmaceuticals Inc
AOBiome LLC
Arovella Therapeutics Ltd
Asarina Pharma AB
AstraZeneca Plc
Astrocyte Pharmaceuticals Inc
Avanir Pharmaceuticals Inc
Axsome Therapeutics Inc
Benuvia Therapeutics Inc
Better Life Pharmaceuticals Inc
Biogen Inc
Biohaven Pharmaceutical Holding Company Ltd
Cerecin Pte Ltd
Ceruvia Lifesciences LLC
Charleston Laboratories Inc
Citragen Pharmaceuticals Inc
Corium Inc
Crossject SA
Crystec Ltd
Curatis AG
DelNova Inc
Dr. Reddy's Laboratories Ltd
Eli Lilly and Co
Epalex Corp
Exxel Pharma Inc
Gubra ApS
H. Lundbeck AS
HEC Pharma Co Ltd
IACTA Pharmaceuticals Inc
InStar Technologies AS
IntelGenx Corp
Invisio Ltd
Ionis Pharmaceuticals Inc
Kallyope Inc
Kissei Pharmaceutical Co Ltd
Klaria Pharma Holding AB
Lateral Pharma Pty Ltd
MannKind Corp
Merck & Co Inc
Microgen
Mydecine Innovations Group Inc
NAL Pharmaceuticals Ltd
NeurAxon Pharma Inc
NutriBand Inc
OWP Pharmaceuticals Inc
Panaxia Pharmaceutical Industries Ltd
PassPort Technologies Inc (USA)
Pharmnovo AB
Pherin Pharmaceuticals Inc
Pulmatrix Inc
Qingdao Chia Tai Haier Pharmaceutical Co Ltd
RAFT Pharmaceuticals
Revance Therapeutics Inc
Saniona AB
Satsuma Pharmaceuticals Inc
Seurat Therapeutics Inc
Shandong Boan Biotechnology Co Ltd
Shanghai Junshi Bioscience Co Ltd
Sorrento Therapeutics Inc
Teva Pharmaceutical Industries Ltd
Tremeau Pharmaceuticals Inc
Trevena Inc
Trigemina Inc
TrioxBio Inc
Vaxxinity Inc
Xoc Pharmaceuticals Inc
Zosano Pharma Corp
Migraine – Drug Profiles
(clonidine + naltrexone) – Drug Profile
(dextromethorphan + quinidine sulfate) – Drug Profile
(meloxicam + rizatriptan) – Drug Profile
(promethazine + sumatriptan) – Drug Profile
ABP-450 – Drug Profile
ACX-101 – Drug Profile
AMG-301 – Drug Profile
AST-003 – Drug Profile
atogepant – Drug Profile
B-244 – Drug Profile
BETR-001 – Drug Profile
BG-00010 – Drug Profile
botulinum toxin type A – Drug Profile
CerSci compounds – Drug Profile
CGN-004 – Drug Profile
ClH-2T – Drug Profile
CR-601 – Drug Profile
dihydroergotamine – Drug Profile
dihydroergotamine mesylate – Drug Profile
dihydroergotamine mesylate (DHE) – Drug Profile
DKI-561 – Drug Profile
Drug for Migraine – Drug Profile
Drug to Agonize 5-HT1B and 5-HT1D Receptors for Migraine – Drug Profile
Elyxyb – Drug Profile
EP-102 – Drug Profile
eptinezumab – Drug Profile
erenumab – Drug Profile
flindokalner – Drug Profile
fospropofol – Drug Profile
fremanezumab – Drug Profile
frovatriptan succinate – Drug Profile
galcanezumab – Drug Profile
HEC-137076 – Drug Profile
histamine dihydrochloride – Drug Profile
InStrip – Drug Profile
IONIS-PKKRx – Drug Profile
JS-010 – Drug Profile
KCZ-1279 – Drug Profile
ketoprofen – Drug Profile
KL-00204 – Drug Profile
KL-003 – Drug Profile
KL-00406 – Drug Profile
lacosamide – Drug Profile
lasmiditan – Drug Profile
LAT-8881 – Drug Profile
LuAG-09222 – Drug Profile
LY-3451838 – Drug Profile
Migraine – Drug Profile
Migraine – Drug Profile
Monoclonal Antibody to Inhibit CGRP for Migraine – Drug Profile
MTR-106 – Drug Profile
naltrexone – Drug Profile
NXN-188 – Drug Profile
NYPRG-101 – Drug Profile
onabotulinumtoxinA biosimilar – Drug Profile
oxytocin – Drug Profile
PAR-650097 – Drug Profile
PGSN-010 – Drug Profile
PH-80M – Drug Profile
PH-81 – Drug Profile
picotamide – Drug Profile
PL-37 – Drug Profile
propofol hemisuccinate – Drug Profile
psilocybin – Drug Profile
pyridostigmine – Drug Profile
Recombinant Protein to Activate Insulin Like Growth Factor 1 Receptor for Migraine – Drug Profile
RFT-001 – Drug Profile
rimegepant sulfate ODT – Drug Profile
rizatriptan – Drug Profile
rizatriptan benzoate – Drug Profile
rizatriptan benzoate ODF – Drug Profile
rofecoxib – Drug Profile
RT-002 – Drug Profile
SAN-711 – Drug Profile
sepranolone – Drug Profile
Small Molecule to Inhibit GABA Transaminase for Migraine and Status Epilepticus – Drug Profile
Small Molecules to Agonize CB1 and CB2 for Migraine – Drug Profile
Small Molecules to Inhibit CGRP for Migraine and Osteoarthritis Pain – Drug Profile
SUD-019 – Drug Profile
sumatriptan – Drug Profile
sumatriptan succinate – Drug Profile
timolol – Drug Profile
topiramate – Drug Profile
tricaprilin – Drug Profile
TRV-250 – Drug Profile
UB-313 – Drug Profile
URB-597 – Drug Profile
URB-937 – Drug Profile
XC-101 – Drug Profile
zavegepant hydrochloride – Drug Profile
zolmitriptan – Drug Profile
Migraine – Dormant Projects
Migraine – Discontinued Products
Migraine – Product Development Milestones
Featured News & Press Releases
Sep 13, 2022: Vaxxinity announces first subjects dosed in phase 1 clinical trial of UB-313 for preventive treatment of migraine
Sep 11, 2022: AbbVie to present data from its robust migraine portfolio at the Migraine Trust International Symposium 2022
Sep 08, 2022: Studies show effectiveness of AJOVY (fremanezumab) for treatment of migraine in patients with co-morbid depression
Aug 31, 2022: Real-world administrative claims analysis demonstrates that almost half of migraine patients discontinue barbiturate use after initiation of Nurtec ODT
Aug 02, 2022: Satsuma Pharmaceuticals announces completion of enrollment in SUMMIT pivotal phase 3 efficacy trial of STS101 for the acute treatment of migraine
Aug 01, 2022: Tonix Pharmaceuticals announces issuance of U.S. patent covering potentiated intranasal oxytocin (TNX-1900) for the treatment of pain
Jul 18, 2022: AbbVie seeks EMA marketing authorisation for preventive migraine therapy
Jul 12, 2022: Pulmatrix announces first subject dosed in phase 1 study of PUR3100 for acute migraine
Jun 24, 2022: Teva announces promising interim results from its study PEARL, about the impact of AJOVY (fremanezumab)
Jun 21, 2022: Ceruvia Lifesciences submits FDA investigational new drug application for NYPRG-101 migraine prevention program
Jun 21, 2022: AbbVie submits supplemental new drug application to U.S. FDA for Atogepant (QULIPTA) to support label expansion for the preventive treatment of migraine
Jun 16, 2022: Results from the DELIVER study with Vyepti has been published in a top-ranking medical journal
Jun 16, 2022: Satsuma Pharmaceuticals Hosting Key Opinion Leader Webinar on the acute treatment of migraine, DHE, and STS101
Jun 15, 2022: Otsuka obtains approval in Japan for Auto-Injector dosage form for AJOVY subcutaneous injection 225 mg for preventive treatment of migraine
Jun 14, 2022: Tremeau receives may proceed notification from FDA For Phase III program in acute migraine for TRM-201 (Rofecoxib)
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Table 1: Number of Products under Development for Migraine, 2022
Table 2: Number of Products under Development by Companies, 2022
Table 3: Number of Products under Development by Companies, 2022 (Contd..1)
Table 4: Number of Products under Development by Companies, 2022 (Contd..2)
Table 5: Number of Products under Development by Companies, 2022 (Contd..3)
Table 6: Number of Products under Development by Universities/Institutes, 2022
Table 7: Products under Development by Companies, 2022
Table 8: Products under Development by Companies, 2022 (Contd..1)
Table 9: Products under Development by Companies, 2022 (Contd..2)
Table 10: Products under Development by Companies, 2022 (Contd..3)
Table 11: Products under Development by Companies, 2022 (Contd..4)
Table 12: Products under Development by Companies, 2022 (Contd..5)
Table 13: Products under Development by Companies, 2022 (Contd..6)
Table 14: Products under Development by Universities/Institutes, 2022
Table 15: Number of Products by Stage and Target, 2022
Table 16: Number of Products by Stage and Target, 2022 (Contd..1)
Table 17: Number of Products by Stage and Target, 2022 (Contd..2)
Table 18: Number of Products by Stage and Mechanism of Action, 2022
Table 19: Number of Products by Stage and Mechanism of Action, 2022 (Contd..1)
Table 20: Number of Products by Stage and Mechanism of Action, 2022 (Contd..2)
Table 21: Number of Products by Stage and Route of Administration, 2022
Table 22: Number of Products by Stage and Molecule Type, 2022
Table 23: Migraine – Pipeline by 4P Therapeutics LLC, 2022
Table 24: Migraine – Pipeline by AbbVie Inc, 2022
Table 25: Migraine – Pipeline by Acadia Pharmaceuticals Inc, 2022
Table 26: Migraine – Pipeline by Achelios Therapeutics Inc, 2022
Table 27: Migraine – Pipeline by Acherx LLC, 2022
Table 28: Migraine – Pipeline by AEON Biopharma Inc, 2022
Table 29: Migraine – Pipeline by AgoneX Biopharmaceuticals Inc, 2022
Table 30: Migraine – Pipeline by Allodynic Therapeutics LLC, 2022
Table 31: Migraine – Pipeline by Amgen Inc, 2022
Table 32: Migraine – Pipeline by Amneal Pharmaceuticals Inc, 2022
Table 33: Migraine – Pipeline by AOBiome LLC, 2022
Table 34: Migraine – Pipeline by Arovella Therapeutics Ltd, 2022
Table 35: Migraine – Pipeline by Asarina Pharma AB, 2022
Table 36: Migraine – Pipeline by AstraZeneca Plc, 2022
Table 37: Migraine – Pipeline by Astrocyte Pharmaceuticals Inc, 2022
Table 38: Migraine – Pipeline by Avanir Pharmaceuticals Inc, 2022
Table 39: Migraine – Pipeline by Axsome Therapeutics Inc, 2022
Table 40: Migraine – Pipeline by Benuvia Therapeutics Inc, 2022
Table 41: Migraine – Pipeline by Better Life Pharmaceuticals Inc, 2022
Table 42: Migraine – Pipeline by Biogen Inc, 2022
Table 43: Migraine – Pipeline by Biohaven Pharmaceutical Holding Company Ltd, 2022
Table 44: Migraine – Pipeline by Cerecin Pte Ltd, 2022
Table 45: Migraine – Pipeline by Ceruvia Lifesciences LLC, 2022
Table 46: Migraine – Pipeline by Charleston Laboratories Inc, 2022
Table 47: Migraine – Pipeline by Citragen Pharmaceuticals Inc, 2022
Table 48: Migraine – Pipeline by Corium Inc, 2022
Table 49: Migraine – Pipeline by Crossject SA, 2022
Table 50: Migraine – Pipeline by Crystec Ltd, 2022
Table 51: Migraine – Pipeline by Curatis AG, 2022
Table 52: Migraine – Pipeline by DelNova Inc, 2022
Table 53: Migraine – Pipeline by Dr. Reddy's Laboratories Ltd, 2022
Table 54: Migraine – Pipeline by Eli Lilly and Co, 2022
Table 55: Migraine – Pipeline by Epalex Corp, 2022
Table 56: Migraine – Pipeline by Exxel Pharma Inc, 2022
Table 57: Migraine – Pipeline by Gubra ApS, 2022
Table 58: Migraine – Pipeline by H. Lundbeck AS, 2022
Table 59: Migraine – Pipeline by HEC Pharma Co Ltd, 2022
Table 60: Migraine – Pipeline by IACTA Pharmaceuticals Inc, 2022
Table 61: Migraine – Pipeline by InStar Technologies AS, 2022
Table 62: Migraine – Pipeline by IntelGenx Corp, 2022
Table 63: Migraine – Pipeline by Invisio Ltd, 2022
Table 64: Migraine – Pipeline by Ionis Pharmaceuticals Inc, 2022
Table 65: Migraine – Pipeline by Kallyope Inc, 2022
Table 66: Migraine – Pipeline by Kissei Pharmaceutical Co Ltd, 2022
Table 67: Migraine – Pipeline by Klaria Pharma Holding AB, 2022
Table 68: Migraine – Pipeline by Lateral Pharma Pty Ltd, 2022
Table 69: Migraine – Pipeline by MannKind Corp, 2022
Table 70: Migraine – Pipeline by Merck & Co Inc, 2022
Table 71: Migraine – Pipeline by Microgen, 2022
Table 72: Migraine – Pipeline by Mydecine Innovations Group Inc, 2022
Table 73: Migraine – Pipeline by NAL Pharmaceuticals Ltd, 2022
Table 74: Migraine – Pipeline by NeurAxon Pharma Inc, 2022
Table 75: Migraine – Pipeline by NutriBand Inc, 2022
Table 76: Migraine – Pipeline by OWP Pharmaceuticals Inc, 2022
Table 77: Migraine – Pipeline by Panaxia Pharmaceutical Industries Ltd, 2022
Table 78: Migraine – Pipeline by PassPort Technologies Inc (USA), 2022
Table 79: Migraine – Pipeline by Pharmnovo AB, 2022
Table 80: Migraine – Pipeline by Pherin Pharmaceuticals Inc, 2022
Table 81: Migraine – Pipeline by Pulmatrix Inc, 2022
Table 82: Migraine – Pipeline by Qingdao Chia Tai Haier Pharmaceutical Co Ltd, 2022
Table 83: Migraine – Pipeline by RAFT Pharmaceuticals, 2022
Table 84: Migraine – Pipeline by Revance Therapeutics Inc, 2022
Table 85: Migraine – Pipeline by Saniona AB, 2022
Table 86: Migraine – Pipeline by Satsuma Pharmaceuticals Inc, 2022
Table 87: Migraine – Pipeline by Seurat Therapeutics Inc, 2022
Table 88: Migraine – Pipeline by Shandong Boan Biotechnology Co Ltd, 2022
Table 89: Migraine – Pipeline by Shanghai Junshi Bioscience Co Ltd, 2022
Table 90: Migraine – Pipeline by Sorrento Therapeutics Inc, 2022
Table 91: Migraine – Pipeline by Teva Pharmaceutical Industries Ltd, 2022
Table 92: Migraine – Pipeline by Tremeau Pharmaceuticals Inc, 2022
Table 93: Migraine – Pipeline by Trevena Inc, 2022
Table 94: Migraine – Pipeline by Trigemina Inc, 2022
Table 95: Migraine – Pipeline by TrioxBio Inc, 2022
Table 96: Migraine – Pipeline by Vaxxinity Inc, 2022
Table 97: Migraine – Pipeline by Xoc Pharmaceuticals Inc, 2022
Table 98: Migraine – Pipeline by Zosano Pharma Corp, 2022
Table 99: Migraine – Dormant Projects, 2022
Table 100: Migraine – Dormant Projects, 2022 (Contd..1)
Table 101: Migraine – Dormant Projects, 2022 (Contd..2)
Table 102: Migraine – Dormant Projects, 2022 (Contd..3)
Table 103: Migraine – Dormant Projects, 2022 (Contd..4)
Table 104: Migraine – Dormant Projects, 2022 (Contd..5)
Table 105: Migraine – Discontinued Products, 2022
List of Figures
Figure 1: Number of Products under Development for Migraine, 2022
Figure 2: Number of Products under Development by Companies, 2022
Figure 3: Number of Products under Development by Universities/Institutes, 2022
Figure 4: Number of Products by Top 10 Targets, 2022
Figure 5: Number of Products by Stage and Top 10 Targets, 2022
Figure 6: Number of Products by Top 10 Mechanism of Actions, 2022
Figure 7: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Figure 8: Number of Products by Top 10 Routes of Administration, 2022
Figure 9: Number of Products by Stage and Top 10 Routes of Administration, 2022
Figure 10: Number of Products by Top 10 Molecule Types, 2022
Figure 11: Number of Products by Stage and Top 10 Molecule Types, 2022

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