Diabetic Nephropathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Diabetic Nephropathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Diabetic Nephropathy - Drugs In Development, 2022, provides an overview of the Diabetic Nephropathy (Metabolic Disorders) pipeline landscape.

Diabetic nephropathy is the damage to the kidney occurring due to diabetes. It is characterized by albuminuria, reduction in glomerular filtration rate and high blood pressure. Risk factors include obesity, hypertension, high lipid and sugar levels and smoking. This condition is managed by medication and dietary modification.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Diabetic Nephropathy - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Diabetic Nephropathy (Metabolic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Diabetic Nephropathy (Metabolic Disorders) pipeline guide also reviews of key players involved in therapeutic development for Diabetic Nephropathy and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 1, 5, 30, 12, 1, 36 and 8 respectively. Similarly, the Universities portfolio in Phase I and Preclinical stages comprises 1 and 4 molecules, respectively.

Diabetic Nephropathy (Metabolic Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Diabetic Nephropathy (Metabolic Disorders).
  • The pipeline guide reviews pipeline therapeutics for Diabetic Nephropathy (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Diabetic Nephropathy (Metabolic Disorders) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Diabetic Nephropathy (Metabolic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Diabetic Nephropathy (Metabolic Disorders)
Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Diabetic Nephropathy (Metabolic Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Diabetic Nephropathy (Metabolic Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


Introduction
Global Markets Direct Report Coverage
Diabetic Nephropathy – Overview
Diabetic Nephropathy – Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Diabetic Nephropathy – Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Diabetic Nephropathy – Companies Involved in Therapeutics Development
Aadi Bioscience Inc
AIBIOS Co Ltd
Akebia Therapeutics Inc
Algomedix Inc
Anagenics Ltd
APT Therapeutics Inc
AptaBio Therapeutics Inc
Araim Pharmaceuticals Inc
Astellas Pharma Inc
AstraZeneca Plc
Bayer AG
Betagenon AB
Bird Rock Bio Inc
BLR Bio LLC
Boehringer Ingelheim International GmbH
Bristol-Myers Squibb Co
Caladrius Biosciences Inc
CCRP Therapeutics GmbH
Certa Therapeutics Pty Ltd
ChemoCentryx Inc
Chinook Therapeutics Inc
Corbus Pharmaceuticals Inc
CSL Ltd
Curacle Co Ltd
Daiichi Sankyo Co Ltd
DiaMedica Therapeutics Inc
Dimerix Ltd
Frontbio Co Ltd
Future Medicine Co Ltd
GenKyoTex SA
Gilead Sciences Inc
Glycadia Inc
Gmax Biopharm LLC
GNI Group Ltd
Goldfinch Bio Inc
Guangdong East Sunshine Pharmaceutical Co Ltd
Guangzhou Magpie Pharmaceutical Co Ltd
Guangzhou Nanxin Pharmaceutical Co Ltd
Hua Medicine Shanghai Ltd
Inovio Pharmaceuticals Inc
InSilico Medicine
Inversago Pharma Inc
Johnson & Johnson
Landos Biopharma Inc
MediPost Co Ltd
Merck & Co Inc
Mesoblast Ltd
Mitsubishi Tanabe Pharma Corp
Nanjing Aimeifei Biomedical Technology Co Ltd
Novartis AG
Novo Nordisk AS
Ono Pharmaceutical Co Ltd
Orbsen Therapeutics Ltd
PhytoHealth Corp
Poxel SA
Praetego Inc
ProKidney LLC
RAGE Biotech Pty Ltd
Reata Pharmaceuticals Inc
Rebus Holdings Inc
Scohia Pharma Inc
Secarna Pharmaceuticals GmbH & Co KG
Serodus ASA
Shanghai Alebund Pharmaceuticals Ltd
Shanghai Pharmaceutical Group Co Ltd
siRNAgen Therapeutics Corp
Slate Bio Inc
Sulfateq BV
Unicyte AG
Vidasym Inc
Wuhan Hamilton Bio-technology Co Ltd
Wuhan LL Science and Technology Development Co Ltd
XORTX Therapeutics Inc
ZyVersa Therapeutics Inc
Diabetic Nephropathy – Drug Profiles
A-717 – Drug Profile
Antisense RNAi Oligonucleotide to Inhibit Amphiregulin for Diabetic Nephropathy – Drug Profile
AP-303 – Drug Profile
APT-602 – Drug Profile
APX-115 – Drug Profile
ARP-1536 – Drug Profile
AS-2444697 – Drug Profile
atrasentan hydrochloride – Drug Profile
bardoxolone methyl – Drug Profile
BI-685509 – Drug Profile
BI-690517 – Drug Profile
Biologic for Delayed Graft Function, Diabetic Nephropathy, Kidney Disease, Non Alcoholic Steatohepatitis and Oncology – Drug Profile
BLR-200 – Drug Profile
BMS-002 – Drug Profile
CAB-101 – Drug Profile
canagliflozin – Drug Profile
CHOP 1 – Drug Profile
cibinetide – Drug Profile
CLBS-201 – Drug Profile
cotadutide – Drug Profile
CRB-556 – Drug Profile
CSL-346 – Drug Profile
CU-01 – Drug Profile
DM-199 – Drug Profile
dorzagliatin – Drug Profile
Drugs for Central Nervous System, Immunology, Metabolic Disorders, Dermatology and Ophthalmology – Drug Profile
EPGN-696 – Drug Profile
esaxerenone – Drug Profile
FB-216A11 – Drug Profile
finerenone – Drug Profile
fluorofenidone – Drug Profile
FT-011 – Drug Profile
fulacimstat – Drug Profile
GFB-024 – Drug Profile
GFB-887 – Drug Profile
GLY-230 – Drug Profile
GMA-131 – Drug Profile
GMA-306 – Drug Profile
HEC-73077 – Drug Profile
IC-300 – Drug Profile
IL-233 – Drug Profile
ilacirnon sodium – Drug Profile
imarikiren – Drug Profile
INV-201 – Drug Profile
INV-202 – Drug Profile
IPG-008 – Drug Profile
ISM004-1057D – Drug Profile
JNJ-39933673 – Drug Profile
LABP-69 – Drug Profile
linagliptin – Drug Profile
LJ-2698 – Drug Profile
meflunidone hydrochloride – Drug Profile
MG-132 – Drug Profile
MK-0429 – Drug Profile
MPC-300IV – Drug Profile
MRI-1867 – Drug Profile
nidufexor – Drug Profile
nimacimab – Drug Profile
O-304 – Drug Profile
ONO-2910 – Drug Profile
Orbcel-M – Drug Profile
PHN-033 – Drug Profile
pirfenidone – Drug Profile
praliciguat – Drug Profile
propagermanium – Drug Profile
PTG-6 – Drug Profile
PXL-770 – Drug Profile
QR-060 – Drug Profile
razuprotafib – Drug Profile
RBR-07 – Drug Profile
REACT – Drug Profile
SCO-116 – Drug Profile
SCO-792 – Drug Profile
selonsertib – Drug Profile
SER-130 – Drug Profile
SER-140 – Drug Profile
SER-150 – Drug Profile
setanaxib – Drug Profile
Small Molecule to Block Cav1.3 and Free Radicals for Central Nervous System, Metabolic Disorders and Cardiovascular Diseases – Drug Profile
Small Molecule to Block TRPC6 for Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, Hypertrophy Cardiomyopathy and Kidney Disease – Drug Profile
Small Molecules for Diabetic Nephropathy – Drug Profile
Small Molecules to Agonize ADORA2 for Autoimmune Disorders, Anemia, Atherosclerosis, Infectious Diseases, Metabolic Disorders and Wounds – Drug Profile
Small Molecules to Antagonize Renin-Prorenin Receptor for End-Organ Damage – Drug Profile
Small Molecules to Block TRPC5 for Diabetic Nephropathy – Drug Profile
Small Molecules to Inhibit VAP-1 for Diabetic Nephropathy – Drug Profile
SMUPIV-01 – Drug Profile
SPH-3127 – Drug Profile
SRI-31277 – Drug Profile
Stem Cell Therapy for Pneumonia and Diabetic Nephropathy – Drug Profile
SUL-121 – Drug Profile
TBE-31 – Drug Profile
tozorakimab – Drug Profile
VAR-200 – Drug Profile
VAR-400 – Drug Profile
VGX-1027 – Drug Profile
VS-105 – Drug Profile
XRX-225 – Drug Profile
zibotentan – Drug Profile
Diabetic Nephropathy – Dormant Projects
Diabetic Nephropathy – Discontinued Products
Diabetic Nephropathy – Product Development Milestones
Featured News & Press Releases
Feb 28, 2022: Goldfinch Bio announces positive preliminary data from phase 2 clinical trial evaluating GFB-887 as a precision medicine for patients with focal segmental glomerular sclerosis (FSGS)
Nov 08, 2021: Goldfinch Bio showcases biology, genetic and clinical programs at ASN Kidney Week demonstrating leadership in precision medicines for kidney diseases
Sep 17, 2021: adMare Portfolio Company, Inversago Pharma initiates a phase 1 clinical trial on INV-202, a next generation peripherally-acting CB1 Blocker
Sep 07, 2021: Inversago Pharma initiates a phase 1 clinical trial on INV-202, a next generation peripherally-acting CB1 blocker
Sep 01, 2021: XORTX announces grant of European patent supporting diabetic nephropathy
Aug 28, 2021: Bayer announces KERENDIA (finerenone) reduces the risk of cardiovascular outcomes in new phase III FIGARO-DKD study in adults with chronic kidney disease (Stages 1-4) associated with type 2 diabetes
Aug 17, 2021: Bayer to present late breaking data from Phase III FIGARO-DKD (finerenone) studies
Aug 02, 2021: Shanghai Pharmaceuticals SPH3127 tablets new indications received phase II clinical trial approval notice
Jul 27, 2021: Goldfinch Bio announces upcoming presentations at the 13th International Podocyte Conference
Jun 22, 2021: Caladrius Biosciences to assess its CLBS201 CD34+ cell therapy in diabetic kidney disease
May 13, 2021: Goldfinch Bio initiates phase 1 clinical trial of GFB-024, a novel precision medicine product candidate for patients with severe insulin resistant Diabetic Nephropathy (DN)
Mar 31, 2021: Mitsubishi Tanabe Pharma wins patent infringement lawsuit of Canagliflozin Hydrate in the U.S. district court
Feb 26, 2021: Canagliflozin (TA-7284) has been approved in Taiwan for diabetic nephropathy
Sep 21, 2020: New study offers hope for patients with diabetes and advanced kidney disease
Sep 08, 2020: Publication of a preclinical study: SCO-792, an enteropeptidase inhibitor, may be a new therapeutic agent for diabetic kidney disease
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Table 1: Number of Products under Development for Diabetic Nephropathy, 2022
Table 2: Number of Products under Development by Companies, 2022
Table 3: Number of Products under Development by Companies, 2022 (Contd..1)
Table 4: Number of Products under Development by Companies, 2022 (Contd..2)
Table 5: Number of Products under Development by Companies, 2022 (Contd..3)
Table 6: Number of Products under Development by Universities/Institutes, 2022
Table 7: Products under Development by Companies, 2022
Table 8: Products under Development by Companies, 2022 (Contd..1)
Table 9: Products under Development by Companies, 2022 (Contd..2)
Table 10: Products under Development by Companies, 2022 (Contd..3)
Table 11: Products under Development by Companies, 2022 (Contd..4)
Table 12: Products under Development by Companies, 2022 (Contd..5)
Table 13: Products under Development by Universities/Institutes, 2022
Table 14: Number of Products by Stage and Target, 2022
Table 15: Number of Products by Stage and Target, 2022 (Contd..1)
Table 16: Number of Products by Stage and Target, 2022 (Contd..2)
Table 17: Number of Products by Stage and Mechanism of Action, 2022
Table 18: Number of Products by Stage and Mechanism of Action, 2022 (Contd..1)
Table 19: Number of Products by Stage and Mechanism of Action, 2022 (Contd..2)
Table 20: Number of Products by Stage and Route of Administration, 2022
Table 21: Number of Products by Stage and Molecule Type, 2022
Table 22: Diabetic Nephropathy – Pipeline by Aadi Bioscience Inc, 2022
Table 23: Diabetic Nephropathy – Pipeline by AIBIOS Co Ltd, 2022
Table 24: Diabetic Nephropathy – Pipeline by Akebia Therapeutics Inc, 2022
Table 25: Diabetic Nephropathy – Pipeline by Algomedix Inc, 2022
Table 26: Diabetic Nephropathy – Pipeline by Anagenics Ltd, 2022
Table 27: Diabetic Nephropathy – Pipeline by APT Therapeutics Inc, 2022
Table 28: Diabetic Nephropathy – Pipeline by AptaBio Therapeutics Inc, 2022
Table 29: Diabetic Nephropathy – Pipeline by Araim Pharmaceuticals Inc, 2022
Table 30: Diabetic Nephropathy – Pipeline by Astellas Pharma Inc, 2022
Table 31: Diabetic Nephropathy – Pipeline by AstraZeneca Plc, 2022
Table 32: Diabetic Nephropathy – Pipeline by Bayer AG, 2022
Table 33: Diabetic Nephropathy – Pipeline by Betagenon AB, 2022
Table 34: Diabetic Nephropathy – Pipeline by Bird Rock Bio Inc, 2022
Table 35: Diabetic Nephropathy – Pipeline by BLR Bio LLC, 2022
Table 36: Diabetic Nephropathy – Pipeline by Boehringer Ingelheim International GmbH, 2022
Table 37: Diabetic Nephropathy – Pipeline by Bristol-Myers Squibb Co, 2022
Table 38: Diabetic Nephropathy – Pipeline by Caladrius Biosciences Inc, 2022
Table 39: Diabetic Nephropathy – Pipeline by CCRP Therapeutics GmbH, 2022
Table 40: Diabetic Nephropathy – Pipeline by Certa Therapeutics Pty Ltd, 2022
Table 41: Diabetic Nephropathy – Pipeline by ChemoCentryx Inc, 2022
Table 42: Diabetic Nephropathy – Pipeline by Chinook Therapeutics Inc, 2022
Table 43: Diabetic Nephropathy – Pipeline by Corbus Pharmaceuticals Inc, 2022
Table 44: Diabetic Nephropathy – Pipeline by CSL Ltd, 2022
Table 45: Diabetic Nephropathy – Pipeline by Curacle Co Ltd, 2022
Table 46: Diabetic Nephropathy – Pipeline by Daiichi Sankyo Co Ltd, 2022
Table 47: Diabetic Nephropathy – Pipeline by DiaMedica Therapeutics Inc, 2022
Table 48: Diabetic Nephropathy – Pipeline by Dimerix Ltd, 2022
Table 49: Diabetic Nephropathy – Pipeline by Frontbio Co Ltd, 2022
Table 50: Diabetic Nephropathy – Pipeline by Future Medicine Co Ltd, 2022
Table 51: Diabetic Nephropathy – Pipeline by GenKyoTex SA, 2022
Table 52: Diabetic Nephropathy – Pipeline by Gilead Sciences Inc, 2022
Table 53: Diabetic Nephropathy – Pipeline by Glycadia Inc, 2022
Table 54: Diabetic Nephropathy – Pipeline by Gmax Biopharm LLC, 2022
Table 55: Diabetic Nephropathy – Pipeline by GNI Group Ltd, 2022
Table 56: Diabetic Nephropathy – Pipeline by Goldfinch Bio Inc, 2022
Table 57: Diabetic Nephropathy – Pipeline by Guangdong East Sunshine Pharmaceutical Co Ltd, 2022
Table 58: Diabetic Nephropathy – Pipeline by Guangzhou Magpie Pharmaceutical Co Ltd, 2022
Table 59: Diabetic Nephropathy – Pipeline by Guangzhou Nanxin Pharmaceutical Co Ltd, 2022
Table 60: Diabetic Nephropathy – Pipeline by Hua Medicine Shanghai Ltd, 2022
Table 61: Diabetic Nephropathy – Pipeline by Inovio Pharmaceuticals Inc, 2022
Table 62: Diabetic Nephropathy – Pipeline by InSilico Medicine, 2022
Table 63: Diabetic Nephropathy – Pipeline by Inversago Pharma Inc, 2022
Table 64: Diabetic Nephropathy – Pipeline by Johnson & Johnson, 2022
Table 65: Diabetic Nephropathy – Pipeline by Landos Biopharma Inc, 2022
Table 66: Diabetic Nephropathy – Pipeline by MediPost Co Ltd, 2022
Table 67: Diabetic Nephropathy – Pipeline by Merck & Co Inc, 2022
Table 68: Diabetic Nephropathy – Pipeline by Mesoblast Ltd, 2022
Table 69: Diabetic Nephropathy – Pipeline by Mitsubishi Tanabe Pharma Corp, 2022
Table 70: Diabetic Nephropathy – Pipeline by Nanjing Aimeifei Biomedical Technology Co Ltd, 2022
Table 71: Diabetic Nephropathy – Pipeline by Novartis AG, 2022
Table 72: Diabetic Nephropathy – Pipeline by Novo Nordisk AS, 2022
Table 73: Diabetic Nephropathy – Pipeline by Ono Pharmaceutical Co Ltd, 2022
Table 74: Diabetic Nephropathy – Pipeline by Orbsen Therapeutics Ltd, 2022
Table 75: Diabetic Nephropathy – Pipeline by PhytoHealth Corp, 2022
Table 76: Diabetic Nephropathy – Pipeline by Poxel SA, 2022
Table 77: Diabetic Nephropathy – Pipeline by Praetego Inc, 2022
Table 78: Diabetic Nephropathy – Pipeline by ProKidney LLC, 2022
Table 79: Diabetic Nephropathy – Pipeline by RAGE Biotech Pty Ltd, 2022
Table 80: Diabetic Nephropathy – Pipeline by Reata Pharmaceuticals Inc, 2022
Table 81: Diabetic Nephropathy – Pipeline by Rebus Holdings Inc, 2022
Table 82: Diabetic Nephropathy – Pipeline by Scohia Pharma Inc, 2022
Table 83: Diabetic Nephropathy – Pipeline by Secarna Pharmaceuticals GmbH & Co KG, 2022
Table 84: Diabetic Nephropathy – Pipeline by Serodus ASA, 2022
Table 85: Diabetic Nephropathy – Pipeline by Shanghai Alebund Pharmaceuticals Ltd, 2022
Table 86: Diabetic Nephropathy – Pipeline by Shanghai Pharmaceutical Group Co Ltd, 2022
Table 87: Diabetic Nephropathy – Pipeline by siRNAgen Therapeutics Corp, 2022
Table 88: Diabetic Nephropathy – Pipeline by Slate Bio Inc, 2022
Table 89: Diabetic Nephropathy – Pipeline by Sulfateq BV, 2022
Table 90: Diabetic Nephropathy – Pipeline by Unicyte AG, 2022
Table 91: Diabetic Nephropathy – Pipeline by Vidasym Inc, 2022
Table 92: Diabetic Nephropathy – Pipeline by Wuhan Hamilton Bio-technology Co Ltd, 2022
Table 93: Diabetic Nephropathy – Pipeline by Wuhan LL Science and Technology Development Co Ltd, 2022
Table 94: Diabetic Nephropathy – Pipeline by XORTX Therapeutics Inc, 2022
Table 95: Diabetic Nephropathy – Pipeline by ZyVersa Therapeutics Inc, 2022
Table 96: Diabetic Nephropathy – Dormant Projects, 2022
Table 97: Diabetic Nephropathy – Dormant Projects, 2022 (Contd..1)
Table 98: Diabetic Nephropathy – Dormant Projects, 2022 (Contd..2)
Table 99: Diabetic Nephropathy – Dormant Projects, 2022 (Contd..3)
Table 100: Diabetic Nephropathy – Dormant Projects, 2022 (Contd..4)
Table 101: Diabetic Nephropathy – Discontinued Products, 2022
List of Figures
Figure 1: Number of Products under Development for Diabetic Nephropathy, 2022
Figure 2: Number of Products under Development by Companies, 2022
Figure 3: Number of Products under Development by Universities/Institutes, 2022
Figure 4: Number of Products by Top 10 Targets, 2022
Figure 5: Number of Products by Stage and Top 10 Targets, 2022
Figure 6: Number of Products by Top 10 Mechanism of Actions, 2022
Figure 7: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Figure 8: Number of Products by Top 10 Routes of Administration, 2022
Figure 9: Number of Products by Stage and Top 10 Routes of Administration, 2022
Figure 10: Number of Products by Top 10 Molecule Types, 2022
Figure 11: Number of Products by Stage and Top 10 Molecule Types, 2022

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